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1 Isolation Valves

2 2 TL OF ONTNTS Page 2 Isolation Valves General Information Page 3 Page 4 Page 5 Why choose an Isolation Valve and ommon pplications Isolation Valve Selection Guide 038T Series Isolation Valves Page 7 075T Series Isolation Valves Page 9 100T Series Isolation Valves Page 11 Manifolds & oolube Hit and Hold ircuit ISOLTION VLVS GNRL INFORMTION What is an Isolation Valve? io-hem Valve Isolation Valves are solenoid-operated devices. The valves Spring diaphragm to isolate the solenoid actuation mechanism Solenoid path. Isolation Valves are available in rmature Fluid Outlet iaphragm Fluid Inlet normally closed, normally open and 3-way. When the valve is energized, the solenoid retracts the armature that is attached diaphragm. In a normally closed 3-way valves have three ports referred to as normally closed, normally closed and the common port. Features of an Isolation Valve hoice of valve function. 2-way normally closed 2-way normally open 3-way Isolation Valve can be made entirely from extremely inert materials such as PTF and PK. hoice of materials. Valve bodies are available in PPS, PK and PTF. iaphragms are available in FFKM, PM and PTF. (Not all combinations of materials are available in all sizes or Precisely machined valve appropriate design for your application can be selected from i-directional. io-hem Valve Isolation Valves identify the preferred inlet port on the valve label. However, all valves can inlet and outlet ports. For a normally open valve, the operation is reversed. When the valve is energized, the diaphragm presses down

3 3 Why choose an Isolation Valve? Maximum inertness The use of high performance plastics and polymers such as PTF, PK and FFKM ensures that the liquid being handled by the valve is always in a highly inert environment. There is no contact with any metallic surfaces within the valve. Fast response times Switching time from port-to-port is generally less than 20ms across the range of Isolation Valves. Small footprint in tight spaces within instruments. The largest valve diameter is 1.25 and longest overall length is less than 3. Minimal dead volume Small overall size also helps keep the internal volumes minimized. The pplications Precise, repeatable dispensing of reagents Normally closed Isolation valve Inert Gas Reagent bottle ispense ustom cap Maintaining a repeatable dispense of aggressive (and often very expensive) reagents into an analytical instrument can be problematic with conventional pumping equipment. Some forward thinking instrument designers have abandoned the concept of using a pump and have instead turned to using a io-hem Fluidics Isolation Valve. In such applications, a standard 2-way normally closed isolation valve is connected to a dip tube, which is inserted into the bottom of a reagent bottle. Low pressure nitrogen (or other appropriate inert gas) is introduced separately to blanket the volume above the liquid in the reagent bottle. The pressure inside the bottle (maintained precisely at a calibrated low value) is dispensed is dependent only on the time the valve is open. spirate and ispense ( sip and spit ) Sometimes the volume of liquid to be dispensed needs to be either a) very small, b) extremely precise or c) both. In these situations it is very common to use a precision machined syringe to control the dispense volume. io-hem Fluidics 3-way isolation valves are commonly used as the link between the liquid reservoir, the syringe and the instrument. 3-way valve has three ports; normally open (NO in illustration), normally closed (N) and common (om). The common port is connected to the syringe. When the reservoir and the syringe via the NO port (aspiration or sip ). e-energized ( sip ) om N Flow path NO nergized ( spit ) om N NO Flow path path switches to the N port, which is connected to the instrument (dispense or spit ). lthough standard threaded port valves are common in this application, io- Syringe motion Syringe motion

4 4 Isolation Valve Selection Guide 1. Select valve function: 2-way Normally losed (N), 2-way Normally Open (NO) or 3-way Turn to the page indicated to see full details and ordering information for each valve. 2-way N ody material PTF PPS PK / N- 038T2 (pg. 5) / N- 038T2 (pg. 5) / T2N (pg. 7) / T2N (pg. 7) / T2N (pg. 9) / T2N (pg. 9) -N- 100T2N (pg. 9) / T2N (pg. 9) -N- -N- 2-way NO ody material PTF PPS PK / T2NO (pg. 7) / T2NO (pg. 7) / T2NO (pg. 9) / T2NO (pg. 9) -N- 100T2NO (pg. 9) 3-way ody material PTF PPS PK / T3MP (pg. 7) / T3MP (pg. 7) / T3MP (pg. 9) / T3MP (pg. 9) Polymers referenced in this brochure: PM = ethylene - propylene - diene PK = polyetheretherketone Trademarks oolube is a trademark of io-hem Fluidics Inc. io-hem Valve is a trademark of io-hem Fluidics Inc.

5 5 038T SRIS ISOLTION MINI S 038T Isolation Mini-Valves are 2-way Normally losed valves They are available with either side-located (038T2S) or bottomlocated (038T2) threaded ports hemically resistant PPS or PK body with a choice of PTF, PM or FFKM diaphragm Low power consumption (1.9 Watts, V; 1.9 Watts, V) and minimal heat generation Maximum operating pressure = 20 psig Suitable for vacuum service to 28 Hg 038T2 PK body 038T2S PK body Ordering info, 038T2S series Ordering info, 038T2 series PRT NO. OY MT L I. MT L INT. VOL (µl) PRT NO. OY MT L I. MT L INT. VOL (µl) 12V, threaded side connections, Normally losed, 12V, threaded bottom connections, Normally losed, 038T2S PPS PTF T2S PPS PM T2S P PPS FFKM T2S PK PTF T2S PK PM T2S P PK FFKM T PPS PTF T PPS PM T P PPS FFKM T PK PTF T PK PM T P PK FFKM 18 12V, threaded side connections, Normally losed, 12V, threaded side connections, Normally losed, 038T2S PPS PTF T2S PPS PM T2S P PPS FFKM T2S PK PTF T2S PK PM T2S P PK FFKM T PPS PTF T PPS PM T P PPS FFKM T PK PTF T PK PM T P PK FFKM 35 For 24V replace 038T2x12 with 038T2x24 where x=s (side) or (bottom) ports

6 6 038T SRIS ISOLTION VLVS continued INSTLLTION RWINGS [10.7] 0.93 [24.0] 2.17 [55.0] imensions are in inches [mm] Lead wires not to scale Wires are 28 WG, min 24 [610] long 0.10 [2.5] Ø0.38 [Ø9.5] 0.19 [4.8] 0.75 [19.0] 0.53 [13.5] Ø0.11 / [2.8] hole thru Ø0.22 / [5.6] 0.06 / [1.5] 0.37 [9.4] 0.30 [7.6] Set screw position 038T2 Isolation Valve [10.7] 0.82 [20.8] 2.09 [53.0] imensions are in inches [mm] Lead wires not to scale Wires are 28 WG, min 24 [610] long Ø0.38 [Ø9.5] 0.75 [19.0] 0.53 [13.5] Ø0.11 / [2.8] hole thru Ø0.22 / [5.6] 0.06 / [1.5] 0.62 [15.7] 0.35 [8.9] 0.30 [7.6] Set screw position 038T2S Isolation Valve

7 7 075T SRIS ISOLTION VLVS 075T Isolation Valves are available in 2-way Normally losed, 2-way Normally Open and 3-way styles Widest choice of chemically resistant body materials, PTF, PPS or PK body with a choice of PTF, PM or FFKM diaphragm Low power consumption (2.9 Watts, V; 2.9 Watts, V) and minimal heat generation 075T2N (2-way Normally losed), PTF body 075T2NO (2-way Normally Open), PPS body 075T3MP (3-way), PK body Ordering info, 075T series PRT NO. OY MT L I. MT L M. PRS. (psig) INT. VOL (µl) PRT NO. OY MT L I. MT L M. PRS. (psig) INT. VOL (µl) 12V, threaded side connections, Normally losed, 12V, threaded side connections, Normally Open, T2N12-32 PTF PTF T2N PPS PTF T2N PPS PM T2N P PPS FFKM T2N PK PTF T2N PK PM T2N P PK FFKM V, threaded side connections, Normally losed, 075T2N12-62 PTF PTF T2N PPS PTF T2N PPS PM T2N P PPS FFKM T2N PK PTF T2N PK PM T2N P PK FFKM V, threaded side connections, Normally Open, T2NO12-32 PTF PTF T2NO PPS PTF T2NO PK PTF T2NO12-62 PTF PTF T2NO PPS PTF T2NO PK PTF v = T3MP12-32 PTF PTF T3MP PPS PTF T3MP PPS PM T3MP P PPS FFKM T3MP PK PTF T3MP PK PM T3MP P PK FFKM v = T3MP12-46 PTF PTF T3MP PPS PTF T3MP PPS PM T3MP P PPS FFKM T3MP PK PTF T3MP PK PM T3MP P PK FFKM For 24 V, replace 075Txxx12-xx with 075Txxx24-xx in any of the part numbers listed.

8 8 075T SRIS ISOLTION VLVS continued INSTLLTION RWINGS View on Y Lead wires not to scale Wires are 26 WG, 24 [610] long typ LL models 0.20 [5.1] Set screw position ody dia Ø Y (180 apart) 075T2Nxx T2Nxx-62 Ø 0.88 [22.2] 1.83 [46.5] 1.83 [46.5] 075T2N Normally losed View on Y 0.20 [5.1] F ody dia Ø Y F G (180 apart) G H I 0 075T2NOxx T2NOxx [11.4] Ø 0.88 [22.2] 2.15 [54.6] 2.15 [54.6] Set screw position 075T2NO Normally Open H I J ody dia Ø View on Y Y 0.76 [19.3] 1/4-28 UNF ports typ. 3 places at 0, 90 and T3MP 3-way J K L 075T3MP PTF body 075T3MP PPS/PK body 2.34 [59.4] 2.34 [59.4] Ø 0.88 [22.2] 1.27 [32.2] 1.27 [32.2] imensions are in inches [mm] 075T series Isolation Valves K L

9 9 100T SRIS ISOLTION VLVS 100T Isolation Valves are available in 2-way Normally losed, 2-way Normally Open and 3-way styles 2-way N / 1.6mm, / 2.3mm and / 3.2mm 2-way NO / 1.6mm and / 2.3mm 3-way / 0.81mm and / 1.6mm hemically resistant body materials, PTF, PPS or PK body with a choice of PTF, PM or FFKM diaphragm Low power consumption (4.0 Watts, V; 4.0 Watts, V) and minimal heat generation 100T2N (2-way Normally losed), PTF body Ordering info, 100T series PRT NO. OY MT L I. MT L M. PRS. (psig) 100T2NO (2-way Normally Open), PK body 100T3MP (3-way), PTF body INT. VOL (µl) PRT NO. OY MT L I. MT L M. PRS. (psig) INT. VOL (µl) 12V, threaded side connections, Normally losed, 12V, threaded side connections, Normally Open, T2N12-62 PTF PTF T2N PPS PTF T2N PPS PM T2N P PPS FFKM T2N PK PTF T2N PK PM T2N P PK FFKM T2NO12-62 PTF PTF T2NO PPS PTF T2NO PPS PM T2NO P PPS FFKM T2NO PK PTF T2NO PK PM T2NO P PK FFKM V, threaded side connections, Normally losed, 12V, threaded side connections, Normally Open, T2N12-92 PTF PTF T2N PK PTF T2NO12-92 PTF PTF T2NO PK PTF V, threaded side connections, Normally losed, 100T2N12-125* PTF PTF * 100T2N & 100T2N valves have 8.0 Watts solenoid coils. For 24 V, replace 100Txxx12-xx with 100Txxx24-xx in any of the part numbers listed. v = T3MP12-32 PTF PTF T3MP PPS PTF T3MP PK PTF v = T3MP12-62 PTF PTF T3MP PPS PTF T3MP PK PTF 30 95

10 10 100T SRIS ISOLTION VLVS continued INSTLLTION RWINGS View on Y Lead wires not to scale Wires are 26 WG, 24 [610] long typ LL models 0.20 [5.1] Set screw position ody dia Ø Y (180 apart) 100T2Nxx T2Nxx T2Nxx-125 Ø 1.25 [31.2] 2.20 [56.0] 2.20 [56.0] 2.20 [56.0] 100T2N Normally losed View on Y 0.20 [5.1] F ody dia Ø Y F G (180 apart) G H I 0 Ø 100T2NO LL 2.54 [64.5] 0.45 [11.4] Set screw position 100T2NO Normally Open H I J ody dia Ø View on Y Y 0.76 [19.3] 1/4-28 UNF ports typ. 3 places at 0, 90 and T3MP 3-way J K L Ø 100T3MP LL 2.69 [68.3] 1.67 [42.4] imensions are in inches [mm] 100T series Isolation Valves K L

11 11 MNIFOL MOUNTING The io-hem Valve Isolation Valves described elsewhere in this brochure are supplied with threaded ports making them suitable for installation with standard ¼ However it is common within modern analytical instruments to use save space and eliminate complicated plumbing inside instruments. and normally open isolation valves with a manifold mounting option. Typically, manifold mounted valves have a threaded collar that attaches the valve to the manifold. locating pin ensures the complete manifold interface details. oolube HIT N HOL IRUIT The io-hem Fluidics oolube Hit and Hold circuit has been used very successfully with the full range of Isolation Valves to reduce opening times. The oolube provides the ability to use a temporary higher voltage hit at the start of the energizing cycle. This over-voltage can opening time - depending on the conditions and voltage applied the opening time can be reduced by 50% or more. oolube fter 100ms the oolube automatically reverts to the normal voltage acting as a fuse to protect the circuitry of the valve. There is is cut to the circuit. The oolube includes terminal pins for easy in-line installation. vailability: Isolation Mini-Valves require the oolube-50r, all other sizes use the oolube-r. SRIS OOLU OOLU Time from hit to hold voltage: 100 ms 100 ms Voltage step down percentage: 67% 50% Max input voltage: 36 V 36 V Max input current: 1 amp 1 amp For more information please refer to oolube spec sheet. 079N manifold mounted isolation Valve, showing collar and locating pin USTOMIZ SOLUTIONS W Many of the Isolation Valves we sell are customized to one extent or another. ustomizable options include (but are not limited to): Materials of construction Mounting options Tagging / labeling Length and/or style of connecting leads lectrical terminations ustom manifolds We look forward to working with you to meet your design engineering objectives!