VALVES VALVES SERVICES

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1 7 The io-hem luidics rand MILY io-hem luidics is dedicated to providing instrument manufacturers and laboratories with the industry s best choice of inert, miniature fluid handling components. Under the io-hem Valve brand name we offer a complete fluid system solution for a wide range of industries including analytical chemistry, clinical diagnostics and medical device manufacturers as well as the scientific community. Inert solenoid VLVS and pumps, electric rotary VLVS micro-pumps Isolation valves flow selection VLVS pinch valves electric rotary VLVS manifold assemblies accessories customiztion SRVIS Trademarks Trinamic is a registered trademark of TRINMI Motion ontrol GmbH & o. KG. io-hem Valve is a trademark of io-hem luidics Inc.

2 Solenoid Operated Pinch Valves

3 2 Index Page 3 Page 4 Page 5 Page 6 Page 9 Page 13 Page 14 Page 15 Page 16 Page 18 Pinch Valve Selection Guide eatures of the io-hem Valve Pinch Valve ontoured body, choice of de-energized state, choice of tubing materials Pinch Valve pplications Prevention of shear, handling non-liquid effluents 075P Series Pinch Valves or use with soft-walled tubing with inner diameters from /0.3mm to 1/16 /1.6mm 100P Series Pinch Valves or use with soft-walled tubing with inner diameters from 1/32 /0.8mm to 1/4 /6.4mm 108P Series Multi-Tubing Pinch Valves or use with soft-walled tubing with inner diameters of 1/32 /0.8mm (simultaneous operation of 4, 6 or 8 tubes) Optical Position eedback Sensor & oolube Hit and Hold ircuit Pinch valve connector accessories Mounting Options Tubing for io-hem Valve Pinch Valves Material selection information, tubing sizing selection charts PINH VLVS GNRL INORMTION What is a Pinch Valve? The io-hem Valve Pinch Valve is a solenoid-operated device. It is designed to open and close tubing to achieve controlled fluid flow. Only the inside of the tubing contacts Solenoid rmature Plunger ody Spring Tubing the fluid. nergizing the solenoid retracts the valve plunger. This either opens the tubing (in the normally closed configuration, as shown left) or closes the tubing (normally open configuration). e-energizing the solenoid allows a spring to push the plunger back to its original position. This returns the tubing to its original closed or open position. 3-way valve has both a normally open and a normally closed flow path, which are operated simultaneously. The tubing is held in place by the plunger and precisely sized grooves in the valve body. Why choose a Pinch Valve? There are many reasons to use io-hem Valve Pinch Valves (refer to page 4 for more details) but pinch valves themselves have specific features that lend themselves to particular applications: Unobstructed flow path. Pinch valves create minimal pressure drop, which is important for controlling downstream instrumentation. Unobstructed flow is also important when handling fluids that might shear when forced to flow through complex valve internals (for more details see page 4). Tubing is soft yet durable. Pinch valves are highly tolerant of particulates in the fluid stream (for more details see page 4). Tubing is easy to change. The user can change tubes if a sterile fluid path is required (for instance, blood collection) or when chemicals create clogs (for instance, system waste lines). Zero dead volume. onsecutive samples are not contaminated by the previous one. luid contacts tubing only. The materials of construction of the body and plunger do not have to be highly corrosion resistant, which means pinch valves are often very economical when compared to alternatives. Simple. Pinch valves do not require complicated electronic controls - they are either energized or not. Pinch valves do support the use of Hit and Hold circuits which significantly reduce the power required to hold the valve in its energized position (for more detail see the oolube on page 14).

4 3 Pinch Valve Selection Guide Valves with io-hem Valve silicone or -lex tubing 1. Select the tubing material either silicone, -lex or tubeless. (See page 18 for additional information about these tubing material options.) 2. hoose your required tubing internal diameter or flow rate, then flow configuration - normally closed (N), normally open (NO), 3-way or multi-tube 3. Turn to the pages indicated to see full details and ordering information for each valve. Tubeless pinch valves io-hem Valve Pinch Valves can be supplied tubeless. These valves are manufactured identically to the silicone tubing version and are supplied without tubing. The designation for these valves is xx#, where xx is the size of tube that should be used. Tubing designation 10S/10# 23S/23# Internal diameter / 0.3mm / 0.6mm Silicone tubing / Tubeless low configuration 2-way N 2-way NO 3-way 2 or 3-way dual tube 01S/01# 1/32 / 0.8mm 075P2N (pg. 6) 075P2NO (pg. 6) 075P3MP (pg. 6) 50S/50# / 1.3mm 02S/02# 1/16 / 1.6mm 01S/01# 1/32 / 0.8mm 100P3MP (pg. 10) 100P (pg. 10) 02S/02# 1/16 / 1.6mm 100P2N (pg. 9) 100P2NO (pg. 9) 03S/03# 1/16 / 1.6mm 05S/05# 1/8 / 3.2mm 100P3MP (pg. 10) -lex tubing Tubing Internal low configuration designation diameter 2-way N 2-way NO 3-way 2 or 3-way dual tube / 0.6mm 01 1/32 / 0.8mm 075P2N (pg. 6) 075P2NO (pg. 6) 075P3MP (pg. 6) 02 1/16 / 1.6mm 01 1/32 / 0.8mm 100P3MP (pg. 10) 100P (pg. 10) 02 1/16 / 1.6mm 100P2N (pg. 9) 100P2NO (pg. 9) 03 1/16 / 1.6mm 05 1/8 / 3.2mm 100P3MP (pg. 10) 01 1/32 / 0.8mm Multi-tube 108P (pg. 13) Valves for customer-specific tubing If the customer intends to use the pinch valves with tubing other than io-hem luidics-supplied tubing, this can be easily accommodated. The customer should provide a sample of tubing to io-hem luidics, who will select the appropriate valve size and adjust the stroke and force settings to match the tubing diameter and durometer. io-hem luidics will assign a special part number to this valve - contact your local office for more details. Polymers referenced in this brochure: S/P = acrylonitrile styrene acrylate / polycarbonate PPS = polyphenelyne sulfide POM = polyoxymethylene (cetal resin) PK = polyetheretherketone

5 4 eatures of io-hem Valve Pinch Valves ontoured ody io-hem Valve Pinch Valves incorporate a contoured body which is designed to meet the market demand for better looking and easier to use valves. The contoured body features a smooth profile and enhanced aesthetics with features that benefit not only instrument designers but also the system end-user. hoice of de-energized state io-hem Valve Pinch Valves are supplied in the following standard configurations: 2-way normally closed 2-way normally open 3-way (where one tube, or set of tubes, is normally open and the other normally closed. When the valve is energized the operation is reversed so the normally open tube is closed and the normally closed tube is opened) ual tubing configurations (i.e. two tubes being operated simultaneously) are offered for smaller tubing sizes. Multi-tube pinch valves with 4, 6 or 8 tubes and normally open operation are also available. 2-way Normally losed 2-way Normally Open 3-way hoice of tubing materials io-hem luidics offers two high-purity medical grade tubing materials for pinch valves: Platinum cured silicone tubing -lex tubing io-hem Valve Pinch Valves can also be configured to use customer supplied tubing, within a recommended durometer range of Shore. asy tube insertion The tubing entry area of the valve body is contoured to guide the tubing into its seat. Tubing securely seated Molded grooves hold the tubing securely in the proper position. The gap between the valve plunger and the valve s anvil is slightly smaller than the tubing s outer diameter. The tubing is held in place during operation without need for mechanical locking features. luid flow and pressure drop are minimally affected, achieving approx. 95% of full flow given the nominal tubing inner diameter. ontinuous duty io-hem Valve Pinch Valves can remain in the fully energized state indefinitely without damage to the valve or the tubing. Valve body is contoured to aid tube insertion. Grooved insert clearly identifies the tubing size. Low power consumption The pinch valves efficient construction permits the use of low wattage solenoid coils, ranging from 2.8 Watt for 075-series valves to 8.1 Watt for 100-series valves, which in turn minimizes heat generation. oth power usage and heat generation can be lowered further by stepping down the voltage after actuation by using a oolube Hit and Hold circuit (refer to page 14 for more details).

6 5 Pinch Valve pplications Prevention of shear in sensitive materials Pinch Valves are typically used in on-off applications; applications that don t require flow control or modulation you just want to start and stop the flow. omplex flow path through conventional valve onventional on-off valves often require the fluid to be regulated to move through a convoluted / complex flow path, even when fully open. This can be an issue for biological materials (proteins, N, etc) which can be easily sheared when forced through complicated paths. Pinch Valves offer line-of-sight flow paths where the open tube, even if slightly pinched does not significantly block the flow path. ecause of the slight venturi effect produced by the pinch, flow through the tubing can actually be enhanced rather than restricted. X Line-of-sight flow path through pinch valve X ross-section at X-X, open. Handling of non-liquid effluents Pinch Valves are often used on the waste side of instrumentation, dumping solutions to a collection device or simply out of the instrument. The waste stream can have many components; liquid, particulates, precipitates and coagulations inadvertently formed from mixtures of chemicals. These accumulated non-liquids can lead to coating on the inner surface of a conventional valve. The coating process is uneven and can eventually lead to the valve becoming clogged. Pinch Valves offer a three-fold solution to this problem: 1. The tubing can be pre-treated to prevent the build-up of films. io-hem Valve silicone tubing is Platinum cured which significantly reduces the possibility of film build-up. 2. The tubing is subjected to a very hard squeeze when the valve is closed. This squeeze is particularly effective in removing any film build-up 3. If the tubing does become blocked it can quickly and easily be replaced without having to remove the valve from service. ustomized Solutions We understand that many applications require customized solutions. Our design and prototyping expertise enables us to offer simple modifications of standard products as well as completely customized designs. Many of the pinch valves we sell are customized to one extent or another. ustomizable options include (but are not limited to): Materials of construction Operating voltage (115/220 V) ustomer supplied tubing Mounting options Tagging / labeling Length and/or style of connecting leads lectrical connections We look forward to working with you to meet your design engineering objectives!

7 6 075P Series PINH VLVS or use with soft-walled tubing with inner diameters from /0.3mm to 1/16 /1.6mm ontinuous duty solenoid operated valve. an remain fully energized for indefinite time period Precise stroke and closing force setting to protect tubing and extend valve life hemically resistant PPS plunger and S/P body materials 24 (610mm) lead wires Low power consumption (3.6 Watts or less) and minimal heat generation 075P2N (2-way Normally losed) 075P2NO (2-way Normally Open) 075P3 (3-way) NOT: 1. or 24 V, replace 075P2Nx12 with 075P2Nx24 (or for a 3-way valve replace 075P3MP12 with 075P3MP24) in any of the part numbers listed.. 2-way normally closed valves INNR OUTR PRT NO. IMTR IMTR inch/mm inch/mm MIN PRSSUR inhg vac. MX PRSSUR psi/bar POWR T 21 c Watts. 2-way normally open valves INNR OUTR PRT NO. IMTR IMTR inch/mm inch/mm MIN PRSSUR inhg vac. MX PRSSUR psi/bar POWR T 21 c Watts 12 V valves with silicone tubing, 12 (305mm) length of silicone tubing is installed in the valve P2N12-10S / / 30 / P2N12-23S / / 20 / P2N12-01S 1/32 / 0.8 3/32 / / P2N12-50S / / 15 / P2N12-02S 1/16 / 1.6 1/8 / / V valves with silicone tubing, 12 (305mm) length of silicone tubing is installed in the valve P2NO12-10S / / 30 / P2NO12-23S / / 20 / P2NO12-01S 1/32 / 0.8 3/32 / / P2NO12-50S / / 15 / P2NO12-02S 1/16 / 1.6 1/8 / / V valves with -lex tubing, 12 (305mm) length of -lex tubing is installed in the valve. 075P2N / / 20 / P2N /32 / 0.8 3/32 / / P2N /16 / 1.6 1/8 / / V valves with -lex tubing, 12 (305mm) length of -lex tubing is installed in the valve. 075P2NO / / 20 / P2NO /32 / 0.8 3/32 / / P2NO /16 / 1.6 1/8 / /

8 7 075P Series PINH VLVS continued. 3-way valves (one port normally open, other port normally closed) 2 PRT NO. INNR IMTR inch/mm OUTR IMTR inch/mm MIN PRSSUR inhg vac. MX PRSSUR psi/bar POWR T 21 c Watts 12 V valves with silicone tubing, two 6 (152mm) lengths of silicone tubing joined by Y connector installed in the valve / / 20 / 075P3MP12-23S / 075P3MP12-01S 1/32 / 0.8 3/32 / / / 15 / 075P3MP12-50S / 075P3MP12-02S 1/16 / 1.6 1/8 / V valves with -lex tubing, two 6 (152mm) lengths of -lex tubing joined by Y connector installed in the valve. 075P3MP / / 20 / P3MP /32 / 0.8 3/32 / / P3MP /16 / 1.6 1/8 / / NOTS: 1. or tubeless version use # in place of S 2. The operation of 3-way valves can be compromised by extended continuous operation. Hit and Hold circuit is strongly recommended to reduce heat generation in extended use applications P3MP12-50S Pinch Valve is not molded. vailable options, 075P series pinch valves 1. Quiet operation (suffix = Q ). The quiet option reduces the valve noise level from about 72 d () to less than 50 d (). The quiet option is available for: a. 075P2N 2-way normally closed valves b. 075P2NO 2-way normally open valves The quiet option cannot be used on 075P3MP 3-way valves. The noise level of the 3-way valves is inherently attenuated by the tubing which dampens the motion in both directions. 2. Mounting holes (suffix = M ). Threaded holes situated on the bottom of the valve body. Refer to installation drawing (page 8) for details and dimensions. The mounting holes cannot be used in combination with the manual override button. 3. Position feedback sensor (suffix = ). The feedback sensor provides secondary, independent confirmation of the plunger position (more details on page 14). The feedback option is available for: a. 075P2N 2-way normally closed valves b. 075P3 3-way valves 4. actory-installed mounting flange (suffix = L ). The mounting flanges are available for all 075P pinch valve configurations. They will be installed at a 90º angle to the tubing with the orientation to the outside of the bulkhead. This mounting flange can be purchased as a stand-alone item under part number MU-075 (more details on page 16).. Hit and Hold voltage reduction Within 100 ms of valve actuation, the voltage required to hold the valve in position can be reduced. The voltage step-down results in the dual benefits of power conservation and heat reduction. The amount of the voltage reduction possible is 66% (i.e. 24 Vdc to 8 Vdc or 12 Vdc to 4 Vdc) for all 075P pinch valves that do not incorporate the quiet feature. This results in a power usage reduction of 89%, resulting in a correspondingly large drop in heat generation. or the 075P pinch valves with the quiet feature, voltage can be reduced by 50% (i.e. 24 Vdc to 12 Vdc and 12 Vdc to 6 Vdc) after 100 ms for a power usage drop of 75%. This voltage reduction can be accomplished using the io-hem luidics oolube hit-and-hold circuit (more details on page 14). Quiet Option Option Highlight PT disc rmature ody eatures: Reduces the valve noise level from about 72 d () to less than 50 d (). How it works: PT disc is inserted between the internal components. The disc cushions the motion of the plunger, leading to a substantial reduction in noise. vailability: 075P2N, 075P2NO, 100P2N and 100P2NO valves. Ordering info: dd suffix Q to part number.

9 8 075P Series PINH VLVS continued INSTLLTION RWINGS Lead wires not to scale Wires are 26 WG, min 24 (610mm) long View on X showing optional mounting holes..75in 19.1mm.2in 5.1mm 2X #2-56 UN threaded holes Set screw position variable to +.25" (6.4mm) X.5in 12.7mm 1.89in 48.0mm.62in 15.7mm.125in 3.2mm 075P2N 2-way Normally losed View on X showing optional mounting holes. Lead wires not to scale Wires are 26 WG, min 24 (610mm) long.75in 19.1mm.2in 5.1mm 2X #2-56 UN threaded holes G X.5in 12.7mm G H 2.2in 55.9mm.62in 15.7mm.125in 3.2mm 075P2NO 2-way Normally Open H I Lead wires not to scale Wires are 26 WG, min 24 (610mm) long.75in 19.1mm.6in 15.2mm.21in 5.3mm View on X showing optional mounting holes. 2X #2-56 UN threaded holes I J X.5in 12.7mm J K L Set screw position variable to +.25" (6.4mm) 2.12in 53.8mm.84in 21.3mm 075P3 3-way.132in 3.4mm Pinch Valves 075P series K L

10 9 100P Series PINH VLVS or use with soft-walled tubing with inner diameters from 1/32 /0.8mm to 1/8 /3.2mm ontinuous duty solenoid operated valve. an remain fully energized for indefinite time period Precise stroke and closing force setting to protect tubing and extend valve life hemically resistant PPS plunger and S/P body materials (unless otherwise noted) 24 (610mm) lead wires Low power consumption (mostly 4.0 Watts) and minimal heat generation NOT: 1. or 24 V, replace 100P2Nx12 with 100P2Nx24 (or for a 3-way valve replace 100P3MP12 with 100P3MP24) in any of the part numbers listed.. 2-way normally closed valves. 2-way normally open valves PRT NO. 100P2N (2-way Normally losed) INNR IMTR inch/mm OUTR IMTR inch/mm MIN PRSSUR inhg vac. MX PRSSUR psi/bar 100P2NO (2-way Normally Open) POWR T 21 c Watts PRT NO. INNR IMTR inch/mm 100P3 (3-way) OUTR IMTR inch/mm MIN PRSSUR inhg vac. MX PRSSUR psi/bar POWR T 21 c Watts 12 V valves with silicone tubing, 12 (305mm) length of silicone tubing is installed in the valve P2N12-01S 1/32 / 0.8 3/32 / / P2N12-02S 1/16 / 1.6 1/8 / / P2N12-03S 1/16 / 1.6 3/16 / / P2N12-05S 1/8 / 3.2 1/4 / / V valves with silicone tubing, 12 (305mm) length of silicone tubing is installed in the valve P2NO12-01S 1/32 / 0.8 3/32 / / P2NO12-02S 1/16 / 1.6 1/8 / / P2NO12-03S 1/16 / 1.6 3/16 / / P2NO12-05S 1/8 / 3.2 1/4 / / V valves with -lex tubing, 12 (305mm) length of -lex tubing is installed in the valve. 100P2N /32 / 0.8 3/32 / / P2N /16 / 1.6 1/8 / / P2N /16 / 1.6 3/16 / / P2N /8 / 3.2 1/4 / / V valves with -lex tubing, 12 (305mm) length of -lex tubing is installed in the valve. 100P2NO /32 / 0.8 3/32 / / P2NO /16 / 1.6 1/8 / / P2NO /16 / 1.6 3/16 / / P2NO /8 / 3.2 1/4 / /

11 10. 3-way valves (one port normally open, other port normally closed) 2 PRT NO. INNR IMTR inch/mm OUTR IMTR inch/mm MIN PRSSUR inhg vac. MX PRSSUR psi/bar POWR T 21 c Watts PRT NO. INNR IMTR inch/mm OUTR IMTR inch/mm MIN PRSSUR inhg vac. MX PRSSUR psi/bar POWR T 21 c Watts 12 V valves with silicone tubing, two 6 (152mm) lengths of silicone tubing joined by Y connector installed in the valve. 100P3MP12-01S 1/32 / 0.8 3/32 / / P3MP12-02S 1/16 / 1.6 1/8 / / P3MP12-05S 1/8 / 3.2 1/4 / / V valves with silicone tubing, two 6 (152mm) lengths of -lex tubing joined by Y connector installed in the valve. 100P3MP /32 / 0.8 3/32 / / P3MP /16 / 1.6 1/8 / / P3MP /8 / 3.2 1/4 / / Valves with dual tubing or use with soft-walled tubing with inner diameters of 1/32 / 0.8mm and 1/16 / 1.6mm. eatures of standard 100P series dual-tubing pinch valves are identical to those of single-tubing pinch valves except: The body and plunger material is POM There are two sets of tubing in every valve 100P2N (2-way Normally losed, ual tubing) NOT: 1. or 24 V, replace 100P2Nx12 with 100P2Nx24 (or for a 3-way valve replace 100P3MP12 with 100P3MP24) in any of the part numbers listed. PRT NO. INNR IMTR inch/mm OUTR IMTR inch/mm MIN PRSSUR inhg vac. MX PRSSUR psi/bar POWR T 21 c Watts PRT NO. INNR IMTR inch/mm OUTR IMTR inch/mm MIN PRSSUR inhg vac. MX PRSSUR psi/bar POWR T 21 c Watts 2-way normally closed 12 V valves with silicone tubing, two 12 (305mm) lengths of silicone tubing are installed in the valve P2N12-01S 1/32 / 0.8 3/32 / / P2N12-02S 1/16 / 1.6 1/8 / / way normally closed 12 V valves with -lex tubing, two 12 (305mm) lengths of -lex tubing are installed in the valve. 100P2N /32 / 0.8 3/32 / / P2N /16 / 1.6 1/8 / / way normally open 12 V valves with silicone tubing, two 12 (305mm) lengths of silicone tubing are installed in the valve P2NO12-01S 1/32 / 0.8 3/32 / / P2NO12-02S 1/16 / 1.6 1/8 / / way normally open 12 V valves with -lex tubing, two 12 (305mm) lengths of -lex tubing are installed in the valve. 100P2NO /32 / 0.8 3/32 / / P2NO /16 / 1.6 1/8 / / way 12 V valves with silicone tubing, four 6 (152mm) lengths of silicone tubing joined by Y connectors installed P3MP12-01S 1/32 / 0.8 3/32 / / P3MP12-02S 1/16 / 1.6 1/8 / / way 12 V valves with -lex tubing, four 6 (152mm) lengths of -lex tubing joined by Y connectors installed. 100P3MP /32 / 0.8 3/32 / / P3MP /16 / 1.6 1/8 / / NOTS: 1. or tubeless version use # in place of S 2. The operation of 3-way valves can be compromised by extended continuous operation. Hit and Hold circuit is strongly recommended to reduce heat generation in extended use applications.

12 11. vailable options, 100P series pinch valves 1. Quiet operation (suffix = Q ). The quiet option reduces the valve noise level from about 72 d () to less than 50 d (). The quiet option is available for: a. 100P2N 2-way normally closed valves b. 100P2NO 2-way normally open valves The quiet option cannot be used on 100P3 3-way valves. The noise level of the 3-way valves is inherently attenuated by tubing dampening the motion in both directions. 2. Mounting holes (suffix = M ). Threaded holes situated on the bottom of the valve body. Refer to installation drawing (page 12) for dimensions. The mounting holes cannot be used in combination with the manual override button. 3. Position feedback sensor (suffix = ). The feedback sensor provides secondary, independent confirmation of the plunger position (more details on page 14). The feedback option is available for: a. 100P2N 2-way normally closed valves b. 100P3 3-way valves c. 100P dual tubing valves 4. actory-installed mounting flange (suffix = L ). The mounting flanges are available for all 100P pinch valve configurations. They will be installed at a 90º angle to the tubing with the orientation to the outside of the bulkhead. This mounting flange can be purchased as a stand-alone item under part number MU-100 (more details on page 16).. Hit and Hold voltage reduction Within 100 ms of valve actuation, the voltage required to hold the valve in position can be reduced. The voltage step-down results in the dual benefits of power conservation and heat reduction. The amount of the voltage reduction possible is 66% (i.e. 24 Vdc to 8 Vdc or 12 Vdc to 4 Vdc) for all 100P pinch valves that do not incorporate the quiet feature. This results in a power usage reduction of 89%, resulting in a correspondingly large drop in heat generation. or the 100P pinch valves with the quiet feature, voltage can be reduced by 50% (i.e. 24 Vdc to 12 Vdc and 12 Vdc to 6 Vdc) after 100 ms for a power usage drop of 75%. This voltage reduction can be accomplished using the io-hem luidics oolube hit-and-hold circuit (more details on page 14).

13 12 100P Series PINH VLVS continued INSTLLTION RWINGS Lead wires not to scale Wires are 26 WG, min 24 (610mm) long View on X showing optional mounting holes. 1.0in [ 25.4mm].26in [ 6.6mm ] 2X #4-40 UN threaded holes Set screw position variable to +.25" (6.4mm) X.69in [17.5mm] 2.54in [ 64.5mm ].88in [ 22.4mm ].2in [5.1mm] 100P2N 2-way Normally losed View on X showing optional mounting holes. Lead wires not to scale Wires are 26 WG, min 24 (610mm) long 1.0in [25.4mm].26in [6.6mm] 2X #4-40 UN threaded holes G X.69in [17.5mm] G H 2.85in [72.4mm].88in [22.4mm].2in [5.1mm] 100P2NO 2-way Normally Open H I Lead wires not to scale Wires are 26 WG, min 24 (610mm) long 1.0in [25.4mm].62in [15.7mm].24in [6.1mm] View on X showing optional mounting holes. 2X #4-40 UN threaded holes I J Set screw position variable to +.25" (6.4mm) X.69in [17.5mm] J K L 2.52in [64.0mm].85in [21.6mm] 100P3 3-way.2in [5.1mm] Pinch Valves 100P series K L Installation drawings for 100P series are available on request.

14 13 108P Series MULTI-TUING PINH VLVS or use with soft-walled tubing with inner diameter of 1/32 /0.8mm. Simultaneous operation of 4, 6 or 8 tubes. ontinuous duty solenoid operated valve. an remain fully energized for indefinite time period Precise stroke and closing force setting to protect tubing and extend valve life hemically resistant PK plunger and POM body materials 15-inch (38cm) lead wires Low power consumption (3.5 Watts) and minimal heat generation Integrated flange with mounting holes Stainless steel push bar -lex tubing (silicone tubing is not available for this pinch valve series) NOT: 1. or 24 V, replace 108PxNO12 with 108PxNO24 in any of the part numbers listed. 4, 6 & 8 - tube normally open valves with -lex tubing PRT NO. INNR IMTR inch/mm OUTR IMTR inch/mm MIN PRSSUR inhg vac. MX PRSSUR psi/bar POWR T 21 c Watts PRT NO. 108P8NO (8-tube Normally Open) INNR IMTR inch/mm OUTR IMTR inch/mm MIN PRSSUR inhg vac. MX PRSSUR psi/bar POWR T 21 c Watts 4 tube, 12 V valves with -lex tubing, each length of tubing is 12 (305mm) long. 108P4NO /32 / 0.8 3/32 / / tube, 12 V valves with -lex tubing, each length of tubing is 12 (305mm) long. 108P6NO /32 / 0.8 3/32 / / tube, 12 V valves with -lex tubing, each length of tubing is 12 (305mm) long. 108P8NO /32 / 0.8 3/32 / / INSTLLTION RWINGS Lead wires not to scale Wires are 26 WG, min 24 (610mm) long 1.0in [25.4mm].16in [4.1mm].38in [9.7mm].15in TYP. [3.8mm] Tube is placed in between pins.06in [1.5mm].28in TYP. [7.1mm] Set screw position variable to +.25" (6.4mm) 2.25in [57.2mm] 1.31in 1.69in [33.3mm] [42.9mm] 2.17in [55.1mm].5in [12.7mm] R1.0in [25.4mm].31in.125 [7.9mm].16in THRU 4.1mm.35in [8.9mm] Maximum extension shown will reduce to.32 when actuated Pinch Valve 108P series

15 14 optical position feedback sensor Position feedback is provided through a compact, factory-mounted infrared optical sensor that instantaneously detects the position of the pinch valve pusher/armature assembly. n electrical signal is transmitted back to the instrument control system, confirming whether the valve is open or closed. With no moving parts, the optical sensor has a virtually unlimited life. The position feedback sensor is an essential feature in many critical operations, such as in medical applications. vailability: 075P2N, 100P2N, 075P3, 100P3 and 100P valves lectrical specifications: Input voltage: Maximum output voltage: Maximum output current: 5.0 V 30.0 V 50.0 m Proper valve function is indicated by a drop in feedback voltage when the valve is open. Typical set-up diagram: Voltage Source V max = 30 V I max = 50m Sensor Signal Pull-up resistor ontrol Power Sensor 5 V White wire System Power + _ + Pinch Valve _ 12 or 24 V Red wire lack wire rown wire lue wire eedback Sensor Pinch Valve eedback sensor mounted on 100P2N valve oolube hit and hold circuit The oolube Hit and Hold circuit steps down voltage through Pulse Width Modulation after 100 ms. This reduces power consumption and heat generation while in hold setting and permits faster response and greater force through brief use of voltage above valve nominal rating. There is no power storage and the valve turns off immediately when power is cut to the circuit. The oolube includes terminal pins for easy in-line installation. vailability: oolube is available for LL pinch valve configurations. 100P range pinch valves, 108P range pinch valves and pinch valves with quiet option require the oolube-50r, otherwise select the oolube-r. Specifications: Series coolcube-r coolcube-50r Time from hit to hold voltage: 100 ms 100 ms Voltage step down percentage: 67% 50% Max input voltage: 36 V 36 V Max input current: 1 amp 1 amp Hold voltage with 36 V input: 12 V 18 V Hold voltage with 24 V input: 8 V 12 V Hold voltage with 12 V input: 4 V 6 V Power consumption reduction: 89% 75% oolube or more information please refer to oolube spec sheet.

16 15 PINH VLV ONNTOR SSORIS io-hem Valve Pinch Valves are designed to allow for fast and easy replacement of the tubing that makes up the fluid path through the valve. Inevitably the soft wall tubing has to interface with either other tubing or a threaded port. io-hem luidics offers the following options to provide connectivity between the pinch valve and ancillary instrumentation and equipment. Y-connectors Straight connectors Use to split one soft wall tube into two streams or to combine two inputs into one output. Polypropylene construction, three sizes available: escription PRT no. PK SIZ Y-connector for 1/32 I Y-01P 10 Y-connector for 1/16 I Y-02P 10 Y-connector for 1/8 I Y-05P 10 Use to connect two equal sized tubes. Polypropylene construction, three sizes available: Reducers arbed daptors escription PRT no. PK SIZ Straight connector for 1/32 I S-01P 10 Straight connector for 1/16 I S-02P 10 Straight connector for 1/8 I S-05P 10 Use to connect two un-equal sized tubes. Polypropylene construction, two sizes available: escription PRT no. PK SIZ Reducer for 1/16 I to 1/32 I R-02/-01P 10 Reducer for 1/8 I to 1/16 I R-05/-02P 10 Use to connect soft-walled tubing to threaded port. cetal construction, three sizes available: escription PRT no. PK SIZ daptor for 1mm I to 1/4-28 thread 008N daptor for 1.5mm I to 1/4-28 thread 008N daptor for 3.2mm I to 1/4-28 thread 008N Tubing Replacement tubing for Pinch Valves. io-hem Valve silicone tubing and -lex tubing (refer to page 18 for more details on standard tubing) Silicone tubing dims. PRT no. Oil SIZ I x O S 50 ft I x O S 50 ft 1/32 I x 3/32 O S 50 ft 0.05 I x O S 50 ft 1/16 I x 1/8 O S 50 ft 1/16 I x 3/16 O S 50 ft 1/8 I x 1/4 O S 50 ft -lex tubing dims. PRT no. Oil SIZ I x O ft 1/32 I x 3/32 O ft 1/16 I x 1/8 O ft 1/16 I x 3/16 O ft 1/8 I x 1/4 O ft

17 16 mounting options io-hem Valve Pinch Valves are easy to mount using one of our stock mounting accessories. The MU-series mounting flanges were designed specifically with these pinch valves in mind. The flanges allow direct attachment to a bulkhead - either inside or outside the panel. Screw hole spacing matches dimensions from other manufacturers for simple replacement in existing systems. eatures of MU-series mounting flange: onstructed from sturdy, glass-filled Polypropylene Spring steel retainer and set screw ensure a secure fit Surface withstands alcohol, bleaches and other common cleaning agents Screw hole orientation relative to tubing can be adjusted to fit available system space MU-series mounting flanges Outside bulkhead mounted Inside bulkhead mounted Other options: Mounting rings (MR-075 & MR-100) and mounting clips (M-075 & M-100) are also available. oth provide economic options for securing the valves within an instrument. eatures of MR-series mounting rings: onstructed from luminum Set screw secures ring firmly to valve but can be loosened for re-positioning an be bulkhead mounted, inside or outside Screw hole orientation relative to tubing can be adjusted to fit available system space MR-series Mounting ring eatures of M-series mounting clips: onstructed from Spring Steel Simple construction - no tools required to secure valve into position Holds valve securely inside instrument M-series Mounting clip

18 17 INSTLLTION RWINGS G H Ø MU / 1.00 / 1.25 / 1 8 / 0.32 / 0.22 / 5 64 / 0.10 / MU / 1.25 / 1.58 / 5 32 / 0.42 / 0.32 / 5 64 / 0.12 / ØG imensions are in inches mm MU-series flanges represents round holes on MU-075 and slots (0.20 /5mm long) on MU-100 2x H x Ø MR / 0.75 / 1.13 / 0.20/ 0.50 / MR / 1.00 / 1.38 / 0.20/ 0.50 / Ø imensions are in inches mm MR-series rings H G G H J M / 0.75 / 0.39 / 0.51/ 0.02 / 0.75 / 0.38/ 0.19 / 0.15 / Ø 2 x ØJ M / 1.00 / 0.51 / 0.68/ 0.03 / 0.75 / 0.38/ 0.19 / 0.14 / imensions are in inches mm M-series clips Mounting holes Option Highlight eatures: Mounting holes allow a valve to be mounted directly to a plate or base. How it works: Small tapped holes are drilled directly into the bottom of the valve body. vailability: ll 075P and 100P valves. Ordering info: dd suffix M to part number.

19 18 Tubing for io-hem Valve Pinch Valves Platinum-cured silicone tubing 1. Test Standards. io-hem Valve silicone tubing is tested in accordance to the standards set by the United States Pharmacopoeia National ormulary XVII, 1990, lass VI iological Test for Plastics. It is Masterfile listed (M 819). 2. urability. This tubing has been selected for use with pinch valves. Platinum curing performed on the tubing during the extrusion process imparts superior strength and durability. The tubing has a low compression set and resists sticking shut even after prolonged periods in the closed position. xcellent memory characteristics ensure full opening and unencumbered flow. The silicone tubing is rated for 500,000 pinch valve cycles. 3. Sterilization. The silicone tubing can be sterilized through steam autoclaving, boiling, dry heat, and gamma radiation. 4. Gas permeability. Silicone tubing has a poor gas permeability rating. io-hem Valve Pinch Valves with an S suffix have silicone tubing already installed. The tubing is also available in 50-foot (15-meter) coils. The coils can be ordered under the part numbers listed below: Tubing esignation iameter Pressure Nominal urometer* Inner Outer Minimum Maximum S /0.3mm /2.4mm 28.2 inhg vac. 30 psi / 2.0 bar S /0.6mm /2.4mm 28.2 inhg vac. 20 psi / 1.3 bar S 1/32 /0.8mm 3/32 /2.4mm 28.2 inhg vac. 25 psi / 1.6 bar S 0.05 /1.3mm /3.4mm 28.2 inhg vac. 15 psi / 1.0 bar S 1/16 /1.6mm 1/8 /3.2mm 28.2 inhg vac. 25 psi / 1.6 bar S 1/16 /1.6mm 3/16 /4.8mm 28.2 inhg vac. 25 psi / 1.6 bar S 1/8 /3.2mm 1/4 /6.4mm 28.2 inhg vac. 20 psi / 1.3 bar 50 * Shore -lex tubing 1. Test Standards. The -lex tubing used in io-hem Valve pinch valves is tested in accordance to the standards set by the United States Pharmacopoeia National ormulary XVII, 1990, lass VI iological Test for Plastics. It is Masterfile listed. 2. Material. -lex tubing is made from a thermoplastic elastomer based on styrene-ethylene-butylene. It does not contain leachable plasticizers. 3. hemical compatibility. -lex can be used with many acids and alkalis. It is not recommended for use with oils and organic solvents. 4. urability. This tubing has been selected for use with pinch valves. The tubing has a low compression set and resists sticking shut even after prolonged periods in the closed position. Good memory characteristics ensure full opening and unencumbered flow. -lex tubing is rated for 200,000 pinch valve cycles. 5. Sterilization. -lex tubing can be sterilized through steam autoclaving, ethylene oxide (TO), and gamma radiation. 6. Gas permeability. -lex tubing has a fair gas permeability rating. It has lower gas permeability than silicone. io-hem Valve Pinch Valves with a suffix have -lex tubing already installed. The tubing is also available in 50-foot (15-meter) coils. The coils can be ordered under the part numbers listed below: Tubing esignation iameter Pressure Nominal urometer* Inner Outer Minimum Maximum /0.6mm /2.4mm 28.2 inhg vac. 20 psi / 1.3 bar /32 /0.8mm 3/32 /2.4mm 28.2 inhg vac. 25 psi / 1.6 bar /16 /1.6mm 1/8 /3.2mm 28.2 inhg vac. 25 psi / 1.6 bar /16 /1.6mm 3/16 /4.8mm 28.2 inhg vac. 25 psi / 1.6 bar /8 /3.2mm 1/4 /6.4mm 28.2 inhg vac. 20 psi / 1.3 bar 50 * Shore

20 19 The io-hem luidics rand Mily io-hem luidics is dedicated to providing instrument manufacturers and laboratories with the industry s best choice of inert, miniature fluid handling components. Under the io-hem Valve brand name we offer a complete fluid system solution for a wide range of industries including analytical chemistry, clinical diagnostics and medical device manufacturers as well as the scientific community. Inert solenoid Vlves and pumps, electric rotary Vlves micro-pumps IsolTion valves flow selection Vlves pinch valves electric rotary Vlves manifold assemblies accessories customization services Trademarks -lex is a registered trademark of Saint-Gobain Performance Plastics. oolube is a trademark of io-hem luidics Inc. io-hem Valve is a trademark of io-hem luidics Inc.

21 Isolation Valves

22 2 table of contents Page 2 Isolation Valves General Information Page 3 Page 4 Page 5 Page 7 Page 9 Page 11 Why choose an Isolation Valve and ommon pplications Isolation Valve Selection Guide 038T Series Isolation Valves / 0.81mm and /1.4mm orifice sizes 075T Series Isolation Valves / 0.81mm and /1.4mm orifice sizes (2-way) and / 0.81mm and /1.2mm orifice sizes (3-way) 100T Series Isolation Valves / 1.6mm, / 2.3mm and /3.2mm orifice sizes (2-way N), / 1.6mm and / 2.3mm orifice sizes (2-way NO) and / 0.81mm and /1.6mm orifice sizes (3-way) Manifolds & oolube Hit and Hold ircuit ISOLTION VLVS GNRL INORMTION What is an Isolation Valve? io-hem Valve Isolation Valves are solenoid-operated devices. luid Outlet Spring Solenoid rmature iaphragm luid Inlet The valves use a flexible diaphragm to isolate the solenoid actuation mechanism from the fluid path. Isolation Valves are available in three different configurations; normally closed, normally open and 3-way. When the valve is energized, the solenoid retracts the armature that is attached to a flexible diaphragm. In a normally closed valve, this raises the diaphragm allowing fluid to flow between the inlet and outlet ports. or a normally open valve, the operation is reversed. When the valve is energized, the diaphragm presses down to close the fluid path. 3-way valves have three ports referred to as normally closed, normally open and common. When the valve is de-energized, fluid flows between the normally open and the common port. When the valve is energized, the valve switches and fluid flows between the normally closed and the common port. eatures of an Isolation Valve hoice of valve function. 2-way normally closed 2-way normally open 3-way Inert fluid path. The fluid path in a io-hem Valve Isolation Valve can be made entirely from extremely inert materials such as PT and PK. hoice of materials. Valve bodies are available in PPS, PK and PT. iaphragms are available in KM, PM and PT. (Not all combinations of materials are available in all sizes or configurations). hoice of valve orifice sizes. Precisely machined valve orifice sizes from (0.81mm) to (3.2mm) in three different dimensional frames ensures that the most appropriate design for your application can be selected from standard configurations. i-directional. io-hem Valve Isolation Valves identify the preferred inlet port on the valve label. However, all valves can be used in any flow direction.

23 3 Why choose an Isolation Valve? Maximum inertness The use of high performance plastics and polymers such as PT, PK and KM ensures that the liquid being handled by the valve is always in a highly inert environment. There is no contact with any metallic surfaces within the valve. ast response times Switching time from port-to-port is generally less than 20ms across the range of Isolation Valves. Small footprint io-hem luidics Isolation Valves are specifically designed to be fitted in tight spaces within instruments. The largest valve diameter is 1.25 and longest overall length is less than 3. Minimal dead volume Small overall size also helps keep the internal volumes minimized. The valves are machined precisely to ensure that they have very low internal volumes (refer to specific product pages for details). pplications Precise, repeatable dispensing of reagents Normally closed Isolation valve Inert Gas Reagent bottle ispense ustom cap Maintaining a repeatable dispense of aggressive (and often very expensive) reagents into an analytical instrument can be problematic with conventional pumping equipment. Some forward thinking instrument designers have abandoned the concept of using a pump and have instead turned to using a io-hem luidics Isolation Valve. In such applications, a standard 2-way normally closed isolation valve is connected to a dip tube, which is inserted into the bottom of a reagent bottle. Low pressure nitrogen (or other appropriate inert gas) is introduced separately to blanket the volume above the liquid in the reagent bottle. The pressure inside the bottle (maintained precisely at a calibrated low value) is sufficient to force the reagent liquid up the dip tube. Under normal conditions, the valve is not energized and remains closed so there is no flow. When the valve is energized the diaphragm opens and flow through the valve is established. The isolation valve now becomes a very repeatable fluid dispenser - the amount of liquid dispensed is dependent only on the time the valve is open. spirate and ispense ( sip and spit ) Sometimes the volume of liquid to be dispensed needs to be either a) very small, b) extremely precise or c) both. In these situations it is very common to use a precision machined syringe to control the dispense volume. io-hem luidics 3-way isolation valves are commonly used as the link between the liquid reservoir, the syringe and the instrument. 3-way valve has three ports; normally open (NO in illustration), normally closed (N) and common (om). The common port is connected to the syringe. When the plunger is withdrawn, the valve is not energized and the flow is between the reservoir and the syringe via the NO port (aspiration or sip ). When the syringe is pushed in, the valve is simultaneously energized. The flow path switches to the N port, which is connected to the instrument (dispense or spit ). lthough standard threaded port valves are common in this application, io- hem luidics can, as an option, supply valves with luer fittings to allow direct coupling to the syringe (contact your regional sales office for more details). e-energized ( sip ) om N Syringe motion low path NO N nergized ( spit ) low path om NO Syringe motion

24 4 Isolation Valve Selection Guide 1. Select valve function: 2-way Normally losed (N), 2-way Normally Open (NO) or 3-way 2. Select the orifice size / v valve 3. onfirm that the appropriate materials of construction are available in the specified valve series. 4. Turn to the page indicated to see full details and ordering information for each valve. 2-way N ody material Valve orifice / v PT PPS PK / N- 038T2 (pg. 5) / N- 038T2 (pg. 5) / T2N (pg. 7) / T2N (pg. 7) / T2N (pg. 9) / T2N (pg. 9) -N- 100T2N (pg. 9) / T2N (pg. 9) -N- -N- 2-way NO ody material Valve orifice / v PT PPS PK / T2NO (pg. 7) / T2NO (pg. 7) / T2NO (pg. 9) / T2NO (pg. 9) -N- 100T2NO (pg. 9) 3-way ody material Valve orifice / v PT PPS PK / T3MP (pg. 7) / T3MP (pg. 7) / T3MP (pg. 9) / T3MP (pg. 9) Polymers referenced in this brochure: PM = ethylene - propylene - diene KM = perfluoro elastomer PK = polyetheretherketone PPS = polyphenelyne sulfide PT = polytetrafluoroethylene Trademarks oolube is a trademark of io-hem luidics Inc. io-hem Valve is a trademark of io-hem luidics Inc.

25 5 038T Series ISOLTION mini-vlvs 038T Isolation Mini-Valves are 2-way Normally losed valves They are available with either side-located (038T2S) or bottomlocated (038T2) threaded ports Two orifice sizes are available: / 0.81mm and / 1.4mm esign based on 0.38 (9.5mm) diameter high efficiency solenoid hemically resistant PPS or PK body with a choice of PT, PM or KM diaphragm Low power consumption (1.9 Watts, V; 1.9 Watts, V) and minimal heat generation Maximum operating pressure = 20 psig Suitable for vacuum service to 28 Hg 038T2 PK body 038T2S PK body Ordering info, 038T2S series Ordering info, 038T2 series PRT NO. OY MT L I. MT L INT. VOL (µl) PRT NO. OY MT L I. MT L INT. VOL (µl) 12V, threaded side connections, Normally losed, orifice, v = T2S PPS PT T2S PPS PM T2S P PPS KM T2S PK PT T2S PK PM T2S P PK KM 20 12V, threaded bottom connections, Normally losed, orifice, v = T PPS PT T PPS PM T P PPS KM T PK PT T PK PM T P PK KM 18 12V, threaded side connections, Normally losed, orifice, v = T2S PPS PT T2S PPS PM T2S P PPS KM T2S PK PT T2S PK PM T2S P PK KM 42 12V, threaded side connections, Normally losed, orifice, v = T PPS PT T PPS PM T P PPS KM T PK PT T PK PM T P PK KM 35 or 24V replace 038T2x12 with 038T2x24 where x=s (side) or (bottom) ports

26 6 038T Series ISOLTION VLVS continued INSTLLTION RWINGS [10.7] 1/4-28 UN ports typ. 2 places 0.93 [24.0] 2.17 [55.0] imensions are in inches [mm] Lead wires not to scale Wires are 28 WG, min 24 [610] long 0.10 [2.5] Ø0.38 [Ø9.5] 0.19 [4.8] 0.75 [19.0] 0.53 [13.5] Ø0.11 / [2.8] hole thru Ø0.22 / [5.6] 0.06 / [1.5] 0.37 [9.4] 0.30 [7.6] Set screw position variable to [6.4] 038T2 Isolation Valve [10.7] 0.82 [20.8] 2.09 [53.0] imensions are in inches [mm] Lead wires not to scale Wires are 28 WG, min 24 [610] long Ø0.38 [Ø9.5] 0.75 [19.0] 0.53 [13.5] Ø0.11 / [2.8] hole thru Ø0.22 / [5.6] 0.06 / [1.5] 1/4-28 UN ports typ. 2 places 0.62 [15.7] 0.35 [8.9] 0.30 [7.6] Set screw position variable to [6.4] 038T2S Isolation Valve

27 075T Ser ies ISOLTION VLVS 7 075T Isolation Valves are available in 2-way Normally losed, 2-way Normally Open and 3-way styles Two orifice sizes are available: / 0.81mm and / 1.6mm (0.032 / 0.81mm and / 1.2mm in the 3-way valve) esign based on 0.75 (19.1mm) diameter high efficiency solenoid Widest choice of chemically resistant body materials, PT, PPS or PK body with a choice of PT, PM or KM diaphragm Low power consumption (2.9 Watts, V; 2.9 Watts, V) and minimal heat generation 075T2N (2-way Normally losed), PT body 075T2NO (2-way Normally Open), PPS body 075T3MP (3-way), PK body Ordering info, 075T series PRT NO. OY MT L I. MT L MX. PRS. (psig) INT. VOL (µl) PRT NO. OY MT L I. MT L MX. PRS. (psig) INT. VOL (µl) 12V, threaded side connections, Normally losed, orifice, v = T2N12-32 PT PT T2N PPS PT T2N PPS PM T2N P PPS KM T2N PK PT T2N PK PM T2N P PK KM V, threaded side connections, Normally losed, orifice, v = T2N12-62 PT PT T2N PPS PT T2N PPS PM T2N P PPS KM T2N PK PT T2N PK PM T2N P PK KM V, threaded side connections, Normally Open, orifice, v = T2NO12-32 PT PT T2NO PPS PT V, threaded side connections, Normally Open, orifice, v = T2NO12-62 PT PT T2NO PPS PT T2NO PK PT V, threaded side connections, 3-way, orifice, v = T3MP12-32 PT PT T3MP PPS PT T3MP PPS PM T3MP P PPS KM T3MP PK PT T3MP PK PM T3MP P PK KM V, threaded side connections, 3-way, orifice, v = T3MP12-46 PT PT T3MP PPS PT T3MP PPS PM T3MP P PPS KM T3MP PK PT T3MP PK PM T2NO PK PT T3MP P PK KM or 24 V, replace 075Txxx12-xx with 075Txxx24-xx in any of the part numbers listed.

28 8 075T Series ISOLTION VLVS continued INSTLLTION RWINGS View on Y Lead wires not to scale Wires are 26 WG, 24 [610] long typ LL models 0.20 [5.1] Set screw position variable to [6.4] ody dia Ø Y X Solenoid dia ØS 1/4-28 UN ports typ. 2 places (180 apart) View on X 075T2Nxx T2Nxx-62 Ø ØS 0.75 [19.1] 0.88 [22.2] 1.83 [46.5] 1.83 [46.5] 0.75 [19.1] 0.75 [19.1] 075T2N Normally losed View on Y 0.20 [5.1] ody dia Ø Y X Solenoid dia ØS G 1/4-28 UN ports typ. 2 places (180 apart) View on X G H I 0 075T2NOxx T2NOxx [11.4] Ø ØS 0.75 [19.1] 0.88 [22.2] 2.15 [54.6] 2.15 [54.6] 0.75 [19.1] 0.75 [19.1] Set screw position variable to [6.4] 075T2NO Normally Open H I J ody dia Ø View on Y Y 0.76 [19.3] 1/4-28 UN ports typ. 3 places at 0, 90 and 180 X View on X Solenoid dia ØS 075T3MP 3-way J K L 075T3MP PT body 075T3MP PPS/PK body 2.34 [59.4] 2.34 [59.4] Ø 0.88 [22.2] 0.75 [19.1] 1.27 [32.2] 1.27 [32.2] ØS 0.75 [19.1] 0.75 [19.1] imensions are in inches [mm] 075T series Isolation Valves K L

29 9 100T Series ISOLTION VLVS 100T Isolation Valves are available in 2-way Normally losed, 2-way Normally Open and 3-way styles Multiple orifice sizes are available: 2-way N / 1.6mm, / 2.3mm and / 3.2mm 2-way NO / 1.6mm and / 2.3mm 3-way / 0.81mm and / 1.6mm esign based on 1.0 (25.4mm) diameter high efficiency solenoid hemically resistant body materials, PT, PPS or PK body with a choice of PT, PM or KM diaphragm Low power consumption (4.0 Watts, V; 4.0 Watts, V) and minimal heat generation 100T2N (2-way Normally losed), PT body Ordering info, 100T series PRT NO. OY MT L I. MT L MX. PRS. (psig) 100T2NO (2-way Normally Open), PK body 100T3MP (3-way), PT body INT. VOL (µl) PRT NO. OY MT L I. MT L MX. PRS. (psig) INT. VOL (µl) 12V, threaded side connections, Normally losed, orifice, v = T2N12-62 PT PT T2N PPS PT T2N PPS PM T2N P PPS KM T2N PK PT T2N PK PM T2N P PK KM V, threaded side connections, Normally Open, orifice, v = T2NO12-62 PT PT T2NO PPS PT T2NO PPS PM T2NO P PPS KM T2NO PK PT T2NO PK PM T2NO P PK KM V, threaded side connections, Normally losed, orifice, v = T2N12-92 PT PT T2N PK PT V, threaded side connections, Normally Open, orifice, v = T2NO12-92 PT PT T2NO PK PT V, threaded side connections, Normally losed, orifice, v = T2N12-125* PT PT * 100T2N & 100T2N valves have 8.0 Watts solenoid coils. or 24 V, replace 100Txxx12-xx with 100Txxx24-xx in any of the part numbers listed. 12V, threaded side connections, 3-way, orifice, v = T3MP12-32 PT PT T3MP PPS PT T3MP PK PT V, threaded side connections, 3-way, orifice, v = T3MP12-62 PT PT T3MP PPS PT T3MP PK PT 30 95

30 10 100T Series ISOLTION VLVS continued INSTLLTION RWINGS View on Y Lead wires not to scale Wires are 26 WG, 24 [610] long typ LL models 0.20 [5.1] Set screw position variable to [6.4] ody dia Ø Y X Solenoid dia ØS 1/4-28 UN ports typ. 2 places (180 apart) 100T2Nxx T2Nxx T2Nxx-125 Ø ØS 1.00 [25.4] 1.00 [25.4] 1.25 [31.2] 2.20 [56.0] 2.20 [56.0] 2.20 [56.0] 1.00 [25.4] 1.00 [25.4] 1.00 [25.4] View on X 100T2N Normally losed View on Y 0.20 [5.1] ody dia Ø Y X Solenoid dia ØS G 1/4-28 UN ports typ. 2 places (180 apart) View on X G H I 0 Ø ØS 100T2NO LL 2.54 [64.5] 1.00 [25.4] 1.00 [25.4] 0.45 [11.4] Set screw position variable to [6.4] 100T2NO Normally Open H I J ody dia Ø View on Y Y 0.76 [19.3] 1/4-28 UN ports typ. 3 places at 0, 90 and 180 X View on X Solenoid dia ØS 100T3MP 3-way J K L Ø 100T3MP LL 2.69 [68.3] 1.00 [25.4] 1.67 [42.4] ØS 1.00 [25.4] imensions are in inches [mm] 100T series Isolation Valves K L

31 11 manifold mounting The io-hem Valve Isolation Valves described elsewhere in this brochure are supplied with threaded ports making them suitable for installation with standard 1/4-28 UN fittings and flexible tubing. However it is common within modern analytical instruments to use manifolds instead of tubing and multiple fittings. ustom manifolds save space and eliminate complicated plumbing inside instruments. To meet this demand, io-hem luidics offers both normally closed and normally open isolation valves with a manifold mounting option. Typically, manifold mounted valves have a threaded collar that attaches the valve to the manifold. locating pin ensures the correct orientation and an elastomer gasket seals the flow path. ontact your local io-hem luidics office for more information and complete manifold interface details. oolube hit and hold circuit The io-hem luidics oolube Hit and Hold circuit has been used very successfully with the full range of Isolation Valves to reduce opening times. The oolube provides the ability to use a temporary higher voltage hit at the start of the energizing cycle. This over-voltage can significantly reduce the valve opening time - depending on the conditions and voltage applied the opening time can be reduced by 50% or more. oolube fter 100ms the oolube automatically reverts to the normal voltage acting as a fuse to protect the circuitry of the valve. There is no power storage and the valve turns off immediately when power is cut to the circuit. The oolube includes terminal pins for easy in-line installation. vailability: oolube is available for LL Isolation Valve configurations. 038T2 Isolation Mini-Valves require the oolube-50r, all other sizes use the oolube-r. Specifications: Series coolcube-r OOLube-50r Time from hit to hold voltage: 100 ms 100 ms Voltage step down percentage: 67% 50% Max input voltage: 36 V 36 V Max input current: 1 amp 1 amp or more information please refer to oolube spec sheet. 079N manifold mounted isolation Valve, showing collar and locating pin ustomized Solutions We understand that many applications require customized solutions. Our design and prototyping expertise enables us to offer simple modifications of standard products as well as completely customized designs. Many of the Isolation Valves we sell are customized to one extent or another. ustomizable options include (but are not limited to): Materials of construction Mounting options Tagging / labeling Length and/or style of connecting leads lectrical terminations ustom manifolds We look forward to working with you to meet your design engineering objectives!

32 The io-hem luidics rand MILY io-hem luidics is dedicated to providing instrument manufacturers and laboratories with the industry s best choice of inert, miniature fluid handling components. Under the io-hem Valve brand name we offer a complete fluid system solution for a wide range of industries including analytical chemistry, clinical diagnostics and medical device manufacturers as well as the scientific community. Inert solenoid VLVes and pumps, eletric rotry VLVes micro-pumps Isolation VLVes flow seletion VLVes pinch VLVes electric rotry VLVes manifold assemblies accessories customization services io-hem luidics Inc 85 ulton Street, oonton NJ US t: (973) f: e: sales.us@biochemfluidics.com io-hem luidics Technology (Shanghai) o. Ltd South Metropolis Industrial Park, Jindu Road, Minhang istrict, Shanghai, PR t: f: IVat r1 June 2012 io-hem luidics 2012 / created by dsm-llc.com

33 Solenoid Operated Micro-Pumps 130SP Series Micro-Pump

34 2 Index Page 3 Page 4 Page 5 Micro-Pump Selection Guide Micro-Pump pplications Waste effluent removal, chemcial dosing, pumping of sterlizing solution 120SP Series Micro-Pump Ported Micro-Pumps (1/4-28 UN) for precise dispense volumes from 10 to 60µl Page 7 130SP Series Micro-Pump Ported Micro-Pumps (1/4-28 UN) for precise dispense volumes from 10 to 60µl (inert body) Page 9 Page 11 Page 13 Page SP Series Micro-Pump Ported Micro-Pumps (5/16-24 UN) for precise dispense volumes from 100 to 250µl 139SP Series Micro-Pump Manifold mounted Micro-Pumps for precise dispense volumes from 10 to 60µl Manifolds and Mounting Options Micro-Pumps Tech Tips - operation and installation micro-pumps general informtion What is a Micro-Pump? Micro-Pump is a solenoid operated device designed to provide a precise, repeatable and discrete dispensed volume of fluid. The luid outlet heck valve element Spring Solenoid heck valve element iaphragm luid inlet flow path is isolated from the operating mechanism by a flexible diaphragm. When the solenoid is energized, the diaphragm is retracted creating a partial vacuum within the pump body. This pulls liquid through the inlet check valve () and simultaneously closes the outlet check valve (). When the solenoid is de-energized a spring pushes the diaphragm down, expelling a discrete volume of liquid through check valve while simultaneously closing check valve. Micro-Pumps require a complete on-off cycle for each discrete dispense. Repeatedly cycling the solenoid creates a pulsed flow (refer to ccurate discrete dispense volumes in next column). eatures of the io-hem Valve Micro-Pump Inert materials Our pumps provide a non-metallic inert fluid path for the dispensing of high purity or aggressive fluids. There is a range of different materials available for all the wetted parts of the pumps - body, diaphragm and check valve. Material combinations can be chosen to suit the application (refer to individual product selection pages for standard combinations - custom combinations are available, refer to page 14). ody materials: PPS, PT, PK, POM iaphragm materials: PM, PT heck valve materials: PM, KM, KM Self-priming t start-up, pumps are able to draw air. The suction created by the pumps is sufficient to pull liquids from an unpressurized container located up to 4 3 (1.3m) beneath the pump. Once the pump is primed, it is able to generate around 5psi (0.3bar) pressure, equating to 11 6 (3.5m) of water. ontinuous duty The pumps are capable of continuous duty. They are suitable for up to 20 million actuations, corresponding to nearly 3,000 hours of continuous use at a 2 Hz cycle rate. ccurate discrete dispense volumes ispense volumes range from 20µl to 250µl per cycle. The pumps can be cycled at up to 2 Hz for the smallest version and 1.6 Hz for the largest. Pumps can be operated at less than the maximum cycle rate by increasing the length of the off time. The on time should remain unchanged to retain dispense accuracy.

35 3 Micro-Pump Selection Guide 1. Select pump style; either Ported or Manifold mount and work from the appropriate table: Ported for direct connection with 1/4-28 fittings (5/16-24 for 150SP) Manifold mount for use with manifolds (see page 13) Then: 2. Locate the volumetric characteristics that best suit your needs 3. hoose your preferred body material depending on the level of chemical inertness you require 4. Turn to the pages indicated to see full details and ordering information for each pump. Ported Volumetric output ody Material iscrete Max flow ispense rate (ml/ Vol (µl) min) PT PPS PK POM SP (pg. 7) 120SP (pg. 5) 120SP (pg. 5) 130SP (pg. 7) SP (pg. 9) 150SP (pg. 9) Manifold mounted Volumetric output iscrete Max flow ispense rate (ml/ Vol (µl) min) ody Material PT PPS PK POM SP (pg. 11) 139SP (pg. 11) 139SP (pg. 11) Polymers referenced in this brochure: PM = ethylene-propylene-diene T = ethylene tetrafluoroethylene P = fluorinated ethylene propylene KM = fluorinated elastomer KM = perfluoro elastomer PK = polyetheretherketone POM = polyoxymethylene (cetal resin) PPS = polyphenelyne sulfide PT = polytetrafluoroethylene.

36 4 Micro-Pump pplications Waste effluent removal Many types of analytical instruments incorporate a waste sump or container that collects any liquids that may have leaked inside the instrument. These waste streams can have Level control many constituents and could be regarded as a biohazard if allowed to collect in the bottom of the instrument. Waste sump Micro-Pump Waste solvent container io-hem luidics Micro-Pumps lend themselves to this application because they offer a completely inert flow path capable of handling the most aggressive of effluents, while maintaining repeatable and consistent pumping rates. Micro-Pump can be hooked up to the level control sensor and be cycled as necessary to empty the sump to an external waste solvent container. hemical dosing In this application io-hem luidics Micro-Pumps are used to pre-treat a liquid stream prior to analysis. The pumps are capable of pumping highly aggressive chemical reagents from a remote location (outside of the instrument) and accurately dispense predetermined volumes of the reagents directly into the main liquid stream. This eliminates the need for an intermediate mixing step inside the instrument. Micro-Pumps can be used in either continuous or intermittent mode depending on the demands of the instrument. ggressive chemical reagents Micro-Pump #1 Micro-Pump #2 Water stream Water analyzer Sterilizing application Sterilizing solution can be of a very high purity which almost always translates to additional expense. In this application a io-hem luidics Micro-Pump takes small amounts of the sterilizing liquid Sterilizing liquid Micro-Pump Heating panel Sterilizing box from a reservoir and dispenses very accurate drips onto a heating panel inside a sterilizing chamber. When the liquid hits the panel, it instantly vaporizes forming a sterilizing vapor inside the chamber. The vapor is very efficient at sterilizing the internals of complicated components. The Micro-Pumps provide highly repeatable and consistent delivery of the sterilizing fluid into the chamber. This safe and cost effective method of pumping high purity liquids has proved very successful.

37 5 120SP Series MIRO-pump or precise dispensing between 20 and 60µl and flow rates up to 7.2 ml/min Self-priming 20-60µl discrete dispense volumes Up to 7.2 ml/min maximum flow rate 1/4-28 UN threaded ports The 120SP series Micro-Pumps are solenoid operated, with the operating mechanism isolated from the flow path by a diaphragm. heck valves situated at the inlet and outlet of the pump control the direction of flow. The combination of materials for each component can be selected to best suit your specific application. RRNGMNT Lead wires Solenoid Materials available for the wetted parts are: ody materials: PPS, PK iaphragm materials: PT, PM heck valve materials: PM, KM, KM 120SP series options NOT: or 24 V, replace 120SP12 with 120SP24 in any of the part numbers listed. ody 1/4-28 Inlet & Outlet ports PRT NO. ispense Vol (μl) body Material diaphragm MTerial check Vlve MTerial PRT NO. ispense Vol (μl) body Material diaphragm MTerial check Vlve MTerial 12 V; 20µl dispense 120SP PPS PM PM 120SP1220-4TV 20 PPS PT KM 120SP1220-4TP 20 PPS PT KM 120SP PK PM PM 120SP1220-5TV 20 PK PT KM 120SP1220-5TP 20 PK PT KM 12 V; 30µl dispense 120SP PPS PM PM 120SP1230-4TV 30 PPS PT KM 120SP1230-4TP 30 PPS PT KM 120SP PK PM PM 120SP1230-5TV 30 PK PT KM 120SP1230-5TP 30 PK PT KM 12 V; 40µl dispense 120SP PPS PM PM 120SP1240-4TV 40 PPS PT KM 120SP1240-4TP 40 PPS PT KM 120SP PK PM PM 120SP1240-5TV 40 PK PT KM 120SP1240-5TP 40 PK PT KM 12 V; 50µl dispense 120SP PPS PM PM 120SP1250-4TV 50 PPS PT KM 120SP1250-4TP 50 PPS PT KM 120SP PK PM PM 120SP1250-5TV 50 PK PT KM 120SP1250-5TP 50 PK PT KM 12 V; 60µl dispense (Note: PM diaphragm for all 60 µl options) 120SP PPS PM PM 120SP PK PM PM

38 6 INSTLLTION RWING Lead wires not to scale Wires are 26 WG and min 24 (610mm) long 2x 1/4-28 UN lat bottom port epth of port =.25 min. (6.4mm) Ø1.0 (Ø25.4mm).49 (12.4mm) Outlet.72 (18.3mm) Set screw position variable to +.25 (6mm) (2.5 ) (63.5mm).84 (21.3mm).688 (17.5mm) 2x #4-40 UN Mounting holes Inlet 1.4 (35.6mm) Micro-Pump 120SP series SPIITIONS 120SP luid ata ispense Volume (μl) Set-point accuracy +/- 10% +/- 10% +/- 10% +/- 10% +/- 10% Repeatability +/- 5% +/- 5% +/- 5% +/- 5% +/- 5% Max flow rate (μl/min) Internal vol (μl) Voltage (21 ) 120SP lectrical ata (21 ) ffective continuous max cycle rate 12 V 4.0 Watts 0.32 amps 1.2 Watts 24 V 4.0 Watts 0.16 amps 1.2 Watts 120SP ycle Rates ixed on time Min off time Max cycle rate 150 msec 350 msec 2.0 Hz Recommended tubing for 120SP Inlet & outlet, 1/32 (0.80mm) I, hardwall tubing, PRT NO. 008T SP Micro-Pumps can be cycled at up to 2 Hz. To maintain pumping precision the voltage on time should remain fixed - the pumping rate can be changed by increasing the off time. Voltage (v) a = 150 msec (fixed) b = 350 msec (minimum, adjustable) a b Time (msec)

39 7 130SP Series MIRO-pump or precise dispensing between 20 and 60µl and flow rates up to 7.2 ml/min Self-priming 20-60µl discrete dispense volumes Up to 7.2 ml/min maximum flow rate 1/4-28 UN threaded ports Most inert body material for harshest applications The 130SP series Micro-Pumps are solenoid operated, with the operating mechanism isolated from the flow path by a diaphragm. heck valves situated at the inlet and outlet of the pump control the direction of flow. The combination of materials for each component can be selected to best suit your specific application. RRNGMNT Lead wires Solenoid Materials available for the wetted parts are: ody materials: PT, POM iaphragm materials: PT, PM heck valve materials: PM, KM, KM 130SP series options NOT: or 24 V, replace 130SP12 with 130SP24 in any of the part numbers listed. PRT NO. ispense Vol (μl) body MTerial diaphrgm MTerial check valve MTerial 12 V; 20µl dispense 130SP1220-1TP 20 PT PT KM 130SP1220-6TV 20 POM PT KM 130SP POM PM PM 12 V; 30µl dispense 130SP1230-1TP 30 PT PT KM 130SP1230-6TV 30 POM PT KM 130SP POM PM PM 12 V; 40µl dispense 130SP1240-1TP 40 PT PT KM 130SP1240-6TV 40 POM PT KM 130SP POM PM PM 12 V; 50µl dispense 130SP1250-1TP 50 PT PT KM 130SP1250-6TV 50 POM PT KM 130SP POM PM PM 12 V; 60µl dispense 130SP POM PM PM ody PK support plates (not wetted, PT body only) 1/4-28 Inlet & Outlet ports (shown with Omni-Lok fittings, see page 17)

40 8 INSTLLTION RWING Lead wires not to scale Wires are 26 WG and min 24 (610mm) long Ø1.0 (Ø25.4mm) 2x 1/4-28 UN lat bottom port epth of port =.25 min (6.4mm) Set screw position variable to +.25 (6mm) (2.67 ) (67.8mm) 1.0 (25.4mm) 1.5 (38.1mm) Outlet Inlet 1.0 (25.4mm) Micro-Pump 130SP series PT body POM/PK body im.280 (7.1mm).345 (8.8mm) SPIITIONS 130SP Volumetric ata ispense Volume (μl) Set-point accuracy +/- 10% +/- 10% +/- 10% +/- 10% +/- 10% Repeatability +/- 5% +/- 5% +/- 5% +/- 5% +/- 5% Max flow rate (μl/min) Internal vol (μl) Voltage (21 ) 130SP lectrical ata (21 ) ffective continuous max cycle rate 12 V 4.0 Watts 0.32 amps 1.2 Watts 24 V 4.0 Watts 0.16 amps 1.2 Watts 130SP ycle Rates ixed on time Min off time Max cycle rate 150 msec 350 msec 2.0 Hz Recommended tubing for 130SP Inlet & outlet, 1/32 (0.80mm) I, hardwall tubing, PRT NO. 008T SP Micro-Pumps can be cycled at up to 2 Hz. To maintain pumping precision the voltage on time should remain fixed - the pumping rate can be changed by increasing the off time. Voltage (v) a = 150 msec (fixed) b = 350 msec (minimum, adjustable) a b Time (msec)

41 9 150SP Series miro-pump or precise dispensing between 100 and 250µl and flow rates up to 24 ml/min RRNGMNT Self-priming µl discrete dispense volumes Up to 24 ml/min maximum flow rate 5/16-24 UN threaded ports The 150SP series Micro-Pumps are solenoid operated, with the operating mechanism isolated from the flow path by a diaphragm. heck valves situated at the inlet and outlet of the pump control the direction of flow. The combination of materials for each component can be selected to best suit your specific application. Lead wires Solenoid Materials available for the wetted parts are: ody materials: PPS, PK iaphragm materials: PM heck valve materials: PM ody 150SP series options NOT: or 24 V, replace 150SP12 with 150SP24 in any of the part numbers listed. PRT NO. ispense Vol (μl) body MTerial diaphrgm MTerial check valve MTerial 12 V; 100µl dispense 150SP PPS PM PM 150SP PK PM PM 12 V; 125µl dispense 150SP PPS PM PM 150SP PK PM PM 12 V; 150µl dispense 150SP PPS PM PM 150SP PK PM PM 5/16-24 Inlet & Outlet ports 12 V; 175µl dispense 150SP PPS PM PM 150SP PK PM PM 12 V; 200µl dispense 150SP PPS PM PM 150SP PK PM PM 12 V; 225µl dispense 150SP PPS PM PM 150SP PK PM PM 12 V; 250µl dispense 150SP PPS PM PM 150SP PK PM PM

42 10 INSTLLTION RWING Lead wires not to scale Wires are 22 WG and min 15 (381mm) long Set screw position variable to +.25 (6mm) Ø1.5 (Ø38.1mm) (3.9 ) (99.1mm) 1.35 (34.3mm).51 (13.0mm) 2x 5/16-24 UN lat bottom port epth of port =.31 (7.9mm) Outlet 1.13 (28.7mm) 2x #8-32 UN Mounting holes Inlet 1.13 (28.7mm) 2.16 (54.9mm) Micro-Pump 150SP series SPIITIONS 150SP luid ata ispense Volume (μl) Set-point accuracy +/- 10% +/- 10% +/- 10% +/- 10% +/- 10% +/- 10% +/- 10% Repeatability +/- 5% +/- 5% +/- 5% +/- 5% +/- 5% +/- 5% +/- 5% Max flow rate (μl/min) Internal vol (μl) Voltage (21 ) 150SP lectrical ata (21 ) ffective continuous max cycle rate 12 V 8.0 Watts 0.66 amps 3.2 Watts 24 V 8.0 Watts 0.33 amps 3.2 Watts 150SP ycle Rates ixed on time Min off time Max cycle rate 200 msec 400 msec 1.6 Hz Recommended tubing for 150SP Inlet & outlet, 1/8 (3.2mm) I, hardwall tubing, PRT NUMR 008T SP Micro-Pumps can be cycled at up to 1.6 Hz. To maintain pumping precision the voltage on time should remain fixed - the pumping rate can be changed by increasing the off time. Voltage (v) a = 200 msec (fixed) b = 400 msec (minimum, adjustable) a b Time (msec)

43 11 139SP Series miro-pump or precise dispensing between 20 and 60µl and flow rates up to 7.2 ml/min in a manifold mountable design RRNGMNT Self-priming 20-60µl discrete dispense volumes Up to 7.2 ml/min maximum flow rate Manifold mountable This sibling to the 130SP Micro-Pump duplicates the performance characteristics but is supplied ready for mounting in your manifold. Please contact us if you would like us to supply the manifold (see page 12). Materials available for the wetted parts are: ody materials: PT, POM, PK iaphragm materials: PT, PM heck valve materials: PM, KM, KM 139SP series options NOT: or 24 V, replace 139SP12 with 139SP24 in any of the part numbers listed. Lead wires Solenoid ody PK support plate (not wetted, PT version only) Mounting screws Locating pin PRT NO. ispense Vol (μl) body MTerial diaphrgm MTerial check valve MTerial PRT NO. ispense Vol (μl) body MTerial diaphrgm MTerial check valve MTerial 12 V; 20µl dispense 139SP1220-1TP 20 PT PT KM 139SP1220-5TP 20 PK PT KM 139SP1220-5TV 20 PK PT KM 139SP1220-5T 20 PK PT PM 139SP1220-6TV 20 POM PT KM 139SP POM PM PM 12 V; 30µl dispense 139SP1230-1TP 30 PT PT KM 139SP1230-5TP 30 PK PT KM 139SP1230-5TV 30 PK PT KM 139SP1230-5T 30 PK PT PM 139SP1230-6TV 30 POM PT KM 139SP POM PM PM 12 V; 40µl dispense 139SP1240-1TP 40 PT PT KM 139SP1240-5TP 40 PK PT KM 139SP1240-5TV 40 PK PT KM 139SP1240-5T 40 PK PT PM 139SP1240-6TV 40 POM PT KM 139SP POM PM PM 12 V; 50µl dispense 139SP1250-1TP 50 PT PT KM 139SP1250-5TP 50 PK PT KM 139SP1250-5TV 50 PK PT KM 139SP1250-5T 50 PK PT PM 139SP1250-6TV 50 POM PT KM 139SP POM PM PM 12 V; 60µl dispense 139SP POM PM PM SPIITIONS The 139SP has the same specifications as the 130SP (see page 7)

44 12 INSTLLTION RWING PT body POM/PK body im Ø.096 (2.4mm).125 (3.2mm) im.50 (12.7mm).34 (8.6mm) im.59 (15.0mm).62 (15.7mm) Lead wires not to scale Wires are 26 gauge and min 24 (610mm) long Ø1.0 Ø25.4mm Set screw position variable to +.25 (6mm) (2.10 ) (53.3mm) heck valves and screws included Outlet Ø Locating pin Inlet 2 x #4-40 Socket head cap screw.40 (10.2mm) 2x Ø.125 (3.2mm) thru hole mm mm or other dimensions refer to manifold drawing Micro-Pump 139SP series MNIOL INTR RWING PT body POM/PK body im.280 (7.11mm).345 (8.76mm) im.280 (7.11mm).350 (8.89mm) im Ø.106 (2.69mm).136 (3.45mm) im.600 (15.2mm).380 (9.65mm) Valve outlet Valve inlet 2x.600 ±.005 (15.24mm ±.13mm) ±.003 (±.08mm) ±.003 (±.08mm) Z Z.050 (1.27mm).230 (5.84mm) Section on Z-Z 2x #4-40 UN (16.5mm) MIN THR Ø.145 ±.003 (3.68mm ±.08mm) 2x Ø.063 ±.003 (1.60mm ±.08mm) 2xØ.210 ±.003 (5.33mm ±.08mm) Ø ±.002 (±.05mm) deep Manifold 139SP series

45 13 manifolds ustom-built manifolds are used to organize multiple Micro-Pumps and other luid ontrol evices such as Isolation Valves into an efficient, pre-assembled, space-saving module that is designed to meet your specific flow needs. Manifolds can range from simple blocks for two devices to complex shapes with intricate flow paths for many devices. io-hem luidics has produced complex manifolds for as many as 84 Micro-Pumps on a single block. eatures: Reduction of internal equipment space requirements. llows for the combining of valves, tubing, pumps and connectors into a single, pre-assembled component. limination of unsightly and unmanageable wiring and tubing. Helps to reduce inventory. Reduces production time and costs associated with testing, handling and assembling multiple components. Materials of construction to suit fluid characteristics including, but not limited to; PT, POM, PK, acrylic and PPS. Please contact your local io-hem luidics facility to discuss your manifold requirements with one of our engineers. ustom manifold for (1) 139SP Micro-Pump (shown) and (3) isolation valves (not shown). lue lines indicate the fluid path; the red dots are ruby balls used as plugs. ustom manifold for (2) 139SP Micro- Pumps (not shown). mounting options io-hem Valve Solenoid Operated Micro-Pumps can be installed into your equipment with a variety of mounting options including mounting clips, rings and flanges. Some of the pumps can be mounted directly via mounting holes that are drilled into the pump body. or more details refer to the Mounting ccessories & Options spec sheet. MU-Series Mounting lange M-Series Mounting lip onstructed from sturdy, glassfilled Polypropylene Spring steel retainer ring and set screw ensure a secure fit Surface withstands alcohol, bleaches and other common cleaning agents an be bulkhead mounted, inside or outside Screw hole orientation relative to tubing can be adjusted to fit available system space MR-Series Mounting Ring onstructed from luminum Tightening screw secures ring firmly to pump but can be loosened for re-positioning an be bulkhead mounted, inside or outside Screw hole orientation relative to tubing can be adjusted to fit available system space onstructed from Spring Steel Simple construction - no tools required to secure pump into position Holds pump securely inside instrument Integral Mounting Holes Threaded mounting holes in the base of the pump provide a more permanent way to mount directly to a plate or base Mounting holes are standard on 120SP and 150SP Micro- Pumps

46 14 MIRO-PUMP TH TIPS OPRTING PRMTRS & INSTLLTION TIPS Output volume and accuracy: number of factors influence the output volume of our pumps. In our factory the pump s setpoint is determined using the following test conditions: luid: e-ionized water at 70 /21 ittings: Omni-Lok 1/4-28 inverted cone fittings for the 120SP and 130SP pump families and 5/16-24 inverted cone fittings for the 150SP pumps (see page 13). Tubing: PT tubing with the following dimensions: 120SP and 130SP pump families: Internal diameter of 1/32, 3 /8cm tubing length 14 /35cm. 150SP pumps: Internal diameter of 1/8 on the inlet and 1/16 on the outlet, 3 /8cm tubing length 10 /25cm Pressure: Negligible pressure on both the inlet and outlet ports. ycle rates: 120SP & 130SP pump families: 250ms on / 350ms off 150SP pump family: 250ms on / 750ms off No air or gas bubbles in the line once the priming process is complete. (See the Priming section on right) If your application parameters deviate significantly from the above, you may experience dispense rates that are different from the setpoint. In that case, please contact io-hem luidics to discuss your application and we will make appropriate adjustments for you. Pressure limits: lthough Micro-Pumps are capable of producing outlet pressures of up to 5 psi (0.35 bar) while a dispense is taking place, for optimal dispense accuracy, the pressure on both the inlet and the outlet side of the pump should be kept between ± 0.5 psi (0.035 bar), equivalent to a head of ± 12 (300mm) water. uring the pump s up-stroke, suction is created on the inlet. Positive pressure is generated at the outlet during the down-stroke. When the pump is not actuated, it will shut-off flow as long as the pressure on the inlet does not exceed the maximum holding pressure. To ensure correct operation, pressure on the inlet side should never exceed 2 psi (0.14 bar) even when the pump is in the closed position. The check valves in the pump prevent fluid from flowing against the intended flow direction. Orientation: Pumps should be installed with the solenoid portion of the pump pointing upwards, downwards or in a horizontal position with the outlet on top. This ensures that any air in the system will be evacuated quickly and also minimizes the effects of a pressure head acting to keep the check elements open when they should be closed. Outlet Inlet Preferred mounting positions Lead Wires: s a standard all lead wires are PT coated. Lead wires are provided with stripped ends for easy wiring into your control system - refer to drawings on product pages for more details. ifferent lengths and terminal connectors can be provided - refer to customization notes below. Priming: Micro-Pumps must be fully primed prior to operation to ensure that all air is removed from the pump cavity. Priming is achieved by cycling the pump until no air bubbles are seen in the dispense. This normally takes seconds. xcessive air bubbles in the dispense are generally caused by air leaks due to loose fittings - check all the fittings in the system and tighten accordingly. ustomized Solutions We understand that many applications require customized solutions. Our design and prototyping expertise enables us to offer simple modifications of standard products as well as completely customized designs. Over 90% of the Micro-Pumps we sell are customized to one extent or another. ustomizable options include (but are not limited to): Materials of construction Operating voltage ispense volume Mounting options Tagging / labeling Length and/or style of connecting leads ustom manifolds We look forward to working with you to meet your design engineering objectives!

47 15 The io-hem luidics rand Mily io-hem luidics is dedicated to providing instrument manufacturers and laboratories with the industry s best choice of inert, miniature fluid handling components. Under the io-hem Valve brand name we offer a complete fluid system solution for a wide range of industries including analytical chemistry, clinical diagnostics and medical device manufacturers as well as the scientific community. Inert solenoid Vlves and pumps, electric rotary Vlves micro-pumps IsolTion valves flow selection Vlves pinch valves electric rotary Vlves manifold assemblies accessories customiztion services Trademarks PK is a registered trademark of Victrex plc. io-hem Valve is a trademark of io-hem luidics Inc.

48 low Selection Valves

49 2 table of contents Page 2 low Selection Valve General Information Page 3 Why hoose a low Selection Valve and ommon pplications Page 4 Page 5 Page 6 Page 9 low Selection Valve Selection Guide 040T Series low Selection Valves Valves with [0.81mm] and [1.4mm] orifices and 1.9 Watt solenoids 080T Series low Selection Valves Valves with [0.81mm] and [1.6mm] orifices and 2.6 Watt solenoids 105T Series low Selection Valves Valves with [3.2mm] orifices and 8.0 Watt solenoids LOW SLTION VLVS GNRL INORMTION What is a low Selection Valve? io-hem Valve low Selection Valves combine multiple valve actuators into a single, compact unit. ecause each actuator operates independently, low Selection Valves can combine or select any combination of between 2 and 8 individual source streams. Valves are situated around a central block, providing flow paths of equal length. Spring Solenoid rmature iaphragm ommon port Inlet / outlet ody block 4 port low Selection Valve (1 common port, 4 inlets/outlets) low Selection Valves are similar in construction to io-hem Valve solenoid operated Isolation Valves. flexible diaphragm isolates the solenoid actuation mechanism from the fluid path. When a valve is energized, the solenoid retracts the armature that is attached to the flexible diaphragm. This raises the diaphragm allowing fluid to flow between the common port and an outlet. When de-energized a spring forces the diaphragm down, closing off the flow path. ecause the fluid path can be made from extremely inert materials (such as PT and PK), io-hem Valve low Selection Valves are particularly suitable for use in highly aggressive and / or high purity fluid applications. eatures of a io-hem Valve low Selection Valve. Range of orifice sizes and power ratings. The io-hem Valve low Selection Valve range covers orifice sizes from (0.8mm) to (3.2mm) with solenoids rated from less than 2 Watts to 8 Watts in continuous operation. This range means that standard valves can handle many mixing and flow selection applications. Precise flow characteristics. ach solenoid actuator on the low Selection Valve is individually adjusted at the factory to ensure equal flow rates at the same pressure. ompact, robust construction. ombining 2, 3, 4, 5, 6 or 8 valves into one manifold block saves significant space within an instrument. The integral construction eliminates the need for tubing sets between valves. Minimal dead volume. The manifold is specifically designed to reduce the internal volume of the valve leading to minimal dead volume when compared to single, stand-alone valves or compared to manifolds with removable valves. The elimination of tubing sets further reduces the total internal volume of the system. qual length flow paths. The radial layout of the manifold block ensures that all flow paths are identical. There are no differences in flow path length and timing as would be found in linear manifolds. Inert fluid path. io-hem Valve low Selection Valves employ the same method of construction as the range of Isolation Valves. ll wetted parts are manufactured from inert, non-metallic materials.

50 3 Why choose a low Selection Valve? liminate tubing between valves io-hem Valve low Selection Valves eliminate the need for tubing sets to connect between individual valves thereby reducing the number of connections and potential leak points. quivalence of internal flow paths Unlike linear manifolds or valves connected by tubing sets, low Selection Valve flow paths are all the same length which means they have equal pressure drop, equal response times and equal internal volumes. Individual control of flow paths Unlike other valves with multiple ports, each flow path has its own associated actuation mechanism and can be controlled individually. This means that there is no need to pass one port to connect to another as with rotary valves. conomic considerations low Selection Valves offer an economic alternative to either: a) multiple single valves and their associated, necessary tubing sets, or b) multi-port valves that require sophisticated control systems for operation. pplications 080T6 low Selection Valve. Note: Ports are equidistant from center common port ensuring that all flow paths are identical. io-hem Valve low Selection Valves are typically used in one of two main applications: low Mixing (flow from multiple inlets to one common outlet), and low Selection (flow from common inlet split into multiple outlets). low Mixing When io-hem Valve low Selection Valves are used as flow mixing devices the flow from the inlets can be mixed together into a single stream under a variety of conditions: ach inlet can be selected individually so the outlet is one singular outgoing stream. ny combination of inlets can be selected so the outlet is a mixture of the incoming streams. Outlet composition will depend on pressure and fluid viscosity in each stream. low Selection / Stream Splitting When the flow pattern is reversed, low Selection Valves are used to divert flow from a common port to either a single or multiple outlets: In flow selection applications, the common inlet is diverted to one of the available outlets. or stream splitting, the common inlet is split between the available outlets either in a fixed or adjustable percentage. The split can be controlled from one outlet up to the maximum number of outlets in that valve. ach inlet can be constantly adjusted to form a flow gradient. (Please discuss this special application with your regional sales office) 080T4 low Selection Valve used as flow mixing device 080T4 low Selection Valve in flow splitting application

51 4 low Selection Valve Selection Guide 1. Select the number of valves / inlet ports. ll low Selection Valves have the specified number of inlet ports PLUS a common port. or example, a 3-port valve has a total of four ports (three inlet and one common). 2. Select the orifice size. Orifice sizes range from Ø0.032 (0.81mm) to Ø0.125 (3.2mm). 3. onfirm that the appropriate materials of construction are available in the specified valve series (for material combinations not shown please contact your regional sales office). 4. Turn to the pages indicated to see full details and ordering information for each valve. No. of valves Series: 040T (pg. 5) 080T (pg. 6) 105T (pg. 9) Orifice: ody Mat l PPS PK PPS PK PT PPS PK PT PPS PK PT PT PT PT PT PT PM PM PT PM PM PT KM KM KM KM PT PT PT PT PT PT PT PT PM PM PM PM PT PM PM PT PM PM PT KM KM KM KM KM KM KM KM iaphragm Material PT PT PT PT PT PT PT PT PM PM PM PM PT PM PM PT PM PM PT KM KM KM KM KM KM KM KM PT PT PT PT PT PM PM PT PM PM KM KM KM KM PT PT PT PT PT PM PM PT PM PM PT KM KM KM KM PT PT PT PT PT PM PM PT PM PM KM KM KM KM Polymers referenced in this brochure: PM = ethylene - propylene - diene monomer KM = perfluoro elastomer PK = polyetheretherketone PPS = polyphenelyne sulfide PT = polytetrafluoroethylene

52 5 040t Series low SelTIon VLVS 040T low Selection Valve available with either 3 or 4 valves / inlet ports and two orifice sizes (0.032 / 0.81mm and / 1.4mm) esign based on 0.38 (9.5mm) diameter high efficiency solenoid Valve life above 2 million cycles hemically resistant PPS or PK body with choice of PT, PM or KM diaphragm Low power requirements (1.9 Watts, V; 1.9 Watts, V) and minimal heat generation Maximum operating pressure = 20 psi Ordering info, 040T series PRT NO. OY MT L I. MT L INT. VOL (µl) OM. PORT INLT PORT(ea) 040T low Selection Valve (4 inlet ports, orifice, PPS body, PM diaphragm) PRT NO. OY MT L I. MT L INT. VOL (µl) OM. PORT INLT PORT(ea) 12V, 3-port, orifice 040T PPS PT T PPS PM T P PPS KM T PK PT T PK PM T P PK KM V, 4-port, orifice 040T PPS PT T PPS PM T P PPS KM T PK PT T PK PM T P PK KM V, 3-port, orifice 040T PPS PT T PPS PM T P PPS KM T PK PT T PK PM T P PK KM V, 4-port, orifice 040T PPS PT T PPS PM T P PPS KM T PK PT T PK PM T P PK KM * for 24V replace 040Tx12 with 040Tx24 where x=number of ports Set screw position variable to [6.4] Lead wires not to scale. Wires are 28WG, 24 [610] long Ø0.375 [9.5] ommon port 1/4-28 UN 3 040T3 040T4 1 common port as shown 3 inlets ports at 0, 90 & 270 im 3 = 2.78 [70.6] 1 common port as shown 4 inlets ports as shown im 4 = 3.98 [101.1] [40.1] [8.8] Mounting holes Ø0.156 [4.0] thru typ 2 places [14.2] Inlet ports 1/4-28 UN typ on 0.76 [19.3] P 0.54 [13.7] 0.75 [19.1] 4 low Selection Valve 040T series

53 6 080t Series low Selection VLVS 080T low Selection Valve available with either 2, 3, 4, 5, 6 or 8 valves / inlet ports and two orifice sizes (0.032 / 0.81mm and / 1.6mm) esign based on 0.75 (19.1mm) diameter high efficiency solenoid Valve life above 2 million cycles hemically resistant PT, PPS or PK body with choice of PT, PM or KM diaphragm Low power requirement (2.9 Watts, V; 2.9 Watts, V) and minimal heat generation Maximum operating pressure = 20 psi rom left to right, 080T6 low Selection Valve (PT body), 080T2 low Selection Valve (PT body), 080T4 low Selection Valve (PK body) Ordering info, 080T series PRT NO. OY MT L I. MT L INT. VOL (µl) OM. PORT INLT PORT(ea) PRT NO. OY MT L I. MT L INT. VOL (µl) OM. PORT INLT PORT(ea) 12V, 2-port, orifice 080T PT PT T PPS PT T PPS PM T P PPS KM T PK PT T PK PM T P PK KM V, 4-port, orifice 080T PT PT T PPS PT T PPS PM T P PPS KM T PK PT T PK PM T P PK KM V, 2-port, orifice 080T PT PT T PPS PT T PPS PM T P PPS KM T PK PT T PK PM T P PK KM V, 4-port, orifice 080T PT PT T PPS PT T PPS PM T P PPS KM T PK PT T PK PM T P PK KM V, 3-port, orifice 080T PT PT T PPS PT T PPS PM T P PPS KM T PK PT T PK PM T P PK KM V, 5-port, orifice 080T PT PT T PPS PT T PPS PM T P PPS KM T PK PT T PK PM T P PK KM V, 3-port, orifice 080T PT PT T PPS PT T PPS PM T P PPS KM T PK PT T PK PM T P PK KM V, 5-port, orifice 080T PT PT T PPS PT T PPS PM T P PPS KM T PK PT T PK PM T P PK KM

54 7 Ordering info, 080T series (continued) PRT NO. OY MT L I. MT L INT. VOL (µl) OM. PORT INLT PORT(ea) PRT NO. OY MT L I. MT L INT. VOL (µl) OM. PORT INLT PORT(ea) 12V, 6-port, orifice 080T PT PT T PPS PT T PPS PM T P PPS KM T PK PT T PK PM T P PK KM V, 8-port, orifice 080T PT PT T PPS PT T PPS PM T P PPS KM T PK PT T PK PM T P PK KM V, 6-port, orifice 080T PT PT T PPS PT T PPS PM T P PPS KM T PK PT T PK PM T P PK KM V, 8-port, orifice 080T PT PT T PPS PT T PPS PM T P PPS KM T PK PT T PK PM T P PK KM * for 24V replace 080Tx12 with 080Tx24 where x=number of ports INSTLLTION RWING 080T2 SRIS Ø0.75 [19.1] Set screw position variable to [6.4] Lead wires not to scale. Wires are 26WG, 24 [610] long ommon port 1/4-28 UN 3.13 [79.5] 0.62 [15.7] Inlet ports 1/4-28 UN 2 places typ Ø0.875 [22.2] low Selection Valve 080T2 series

55 8 080T Series low Selection VLVS continued INSTLLTION RWING 080T3-080T Set screw position Lead wires not to scale. Wires are 26WG, 24 [610] long, typ LL models 0 variable to [6.4] typ LL models Inlet ports 1/4-28 UN typ on 0.8 [20.3] P 080T3 1 common port on bottom face at 180 ommon port 3 inlets ports at 0, 90 & 270 1/4-28 UN im 3 = 2.52 [64.0] Mounting holes Ø0.156 [4.0] thru typ 2 places LL models 0.56 [14.2] 0.34 [8.6] SQ. [31.8] 4 080T4 1 common port as shown 4 inlets ports as shown im 4 = 3.78 [96.0] [15.0] typ LL models 1.03 [26.2] typ LL models 300 ommon port 1/4-28 UN Ø0.75 [19.1] typ LL models 60 Inlet ports 1/4-28 UN typ on 1.05 [26.7] P 1.50 [38.1] 5 080T5 080T6 1 common port as shown 5 inlets ports at 0, 60, 120, 240 & 300 im 5 = 2.80 [71.1] 1 common port as shown 6 inlets ports as shown im 6 = 4.10 [104.1] G [15.9] G H 180 H I 1.00 [25.4] I J K Inlet ports 1/4-28 UN typ on 1.55 [39.4] P ommon port 1/4-28 UN 2.00 [50.8] 4.6 [116.8] 080T8 1 common port as shown 8 inlets ports as shown low Selection Valves 080T3-8 series J K L 180 L

56 9 105t Series low Selection VLVS 105T low Selection Valve available with either 2, 3, 4 or 6 valves / inlet ports and a / 3.2mm orifice esign based on 1.0 (25.4mm) diameter high efficiency solenoid Valve life above 2 million cycles hemically resistant PT body with PT diaphragm Low power requirement (8.0 Watts, 0.66 amps at 12V; 8.0 Watts, 0.33 amps at 24V) and minimal heat generation Maximum operating pressure = 10 psi Ordering info, 105T series PRT NO. OY MT L I. MT L INT. VOL (µl) OM. PORT INLT PORT(ea) 105T3 low Selection Valve (3 inlet ports, orifice, PT body, PT diaphragm) PRT NO. OY MT L I. MT L INT. VOL (µl) OM. PORT INLT PORT(ea) 12V, 2-port, orifice 105T PT PT V, 3-port, orifice 105T PT PT V, 4-port, orifice 105T PT PT V, 6-port, orifice 105T PT PT * for 24V replace 105Tx12 with 105Tx24 where x=number of ports INSTLLTION RWING 105T2 SRIS Ø1.00 [25.4] Set screw position variable to [6.4] Lead wires not to scale. Wires are 26WG, 24 [610] long ommon port 1/4-28 UN 4.07 [103.4] 1.12 [28.4] Inlet ports 1/4-28 UN 2 places typ Ø1.25 [31.8] low Selection Valve 105T2 series

57 10 105T Series low Selection VLVS continued INSTLLTION RWING 105T3-105T Set screw position variable to [6.4] typ LL models 0 Lead wires not to scale. Wires are 26WG, 24 [610] long, typ LL models Inlet ports 1/4-28 UN typ on 0.81 [20.6] P 3.19 [81.0] 105T3 1 common port on bottom face at inlets ports at 0, 90 & SQ. [38.1] Mounting holes Ø0.156 [4.0] thru typ 2 places LL models [14.2] 0.34 [8.6] ommon port 1/4-28 UN 0.63 [15.9] 1.19 [30.2] 0 Ø1.00 [25.4] typ LL models Inlet ports 1/4-28 UN typ on 0.81 [20.6] P ommon port 1/4-28 UN SQ. [38.1] 4.80 [121.9] 105T4 1 common port as shown 4 inlets ports as shown G 0.56 [14.2] 0.34 [8.6] G H [15.9] 1.19 [30.2] H I I J ommon port 1/4-28 UN Inlet ports 1/4-28 UN typ on 1.32 [33.5] P 2.00 [50.8] 5.38 [136.7] 105T6 1 common port as shown 6 inlets ports as shown J K L [38.1] [18.8] 1.30 [33.0] low Selection Valves 105T3-6 series K L

58 11 The io-hem luidics rand MIly io-hem luidics is dedicated to providing instrument manufacturers and laboratories with the industry s best choice of inert, miniature fluid handling components. Under the io-hem Valve brand name we offer a complete fluid system solution for a wide range of industries including analytical chemistry, clinical diagnostics and medical device manufacturers as well as the scientific community. Inert solenoid Vlves and pumps, electric rotry Vlves micro-pumps IsolTIon valves flow selection Vlves pinch valves electric rotry Vlves manifold assemblies accessories customiztion SRVIS Trademarks io-hem Valve is a trademark of io-hem luidics Inc.

59 lectric Rotary Valves 6 Port Switching lectric Rotary Valve w/ Stepper motor and controller P

60 2 Index Page 3 Page 4 Page 5 Page 6 lectric Rotary Valve Selection Guide RV- Series lectric Rotary Valves PT/PT rotary valve head assembly (supplied without motor or P) RV-SN Series lectric Rotary Valves - valve with motor PT/PT rotary valve supplied with Trinamic stepper motor RV-S Series lectric Rotary Valves - valve with motor and controller P PT/PT rotary valve supplied with Trinamic stepper motor and intelligent motor controller LTRI ROTRY VLVS GNRL INORMTION What is an lectric Rotary Valve? The io-hem luidics lectric Rotary Valve is a stepper motor operated device used in sample collection, loop injection or flow path selection applications. It is designed to provide an inert flow path for aggressive and/or reactive fluids. The inert path is achieved by aligning holes in a PT rotor with holes in the PT valve body (stator). The rotor is pressed into the valve body creating a tight interference fit seal. The rotor is turned by a close-coupled two-phase hybrid stepper motor. n optoelectronic position sensor inside the valve provides the position of the rotor to a controller P. The P makes fine adjustments as necessary to provide an uninterrupted path. The end-user can program the valve controller to perform desired position sequences - the rotor can move clockwise or counterclockwise to the desired port position. (The io-hem luidics lectric Rotary Valve can also be supplied without the motor and controller - refer to page 4 for more details). eatures of a io-hem luidics lectric Rotary Valve Inert fluid path - the fluid in the valve is in contact with only two components; the PT valve body and the PT rotor. This ensures a completely non-metallic, corrosion-resistant path and means that the non-contact parts can be sourced economically from industry standard components. Multiple flow configurations - the io-hem luidics lectric Rotary Valve is available in five different flow configurations (see page 3 for more details) which ROTOR OY means that the most appropriate design for your application can be selected from standard configurations. Unobstructed flow path - careful and precise machining results in an unobstructed flow path through the valve ensuring minimized dead volumes and providing a lower pressure drop than conventional solenoid mixing valves. Industry standard stepper motor - io-hem luidics lectric Rotary Valves utilize Trinamic QMOT stepper motors and PNdrive motor controllers. OM focused - the RV series lectric Rotary Valve is designed specifically with OM customers in mind. The flow configurations match the most commonly found applications and the 1/4-28 UN fluid port connections allow easy integration into sophisticated systems. Polymers referenced in this brochure: PT = polychlorotrifluoroethylene PT = polytetrafluoroethylene

61 pump pump 3 lectric Rotary Valve Selection Guide The io-hem luidics RV series of lectric Rotary Valves is available in three versions; the RV- series comprises the valve head assembly only with no motor or controller, the RV-SN series couples the valve head assembly to a two-phase hybrid stepper motor to drive the valve s rotor and the RV-S series adds an intelligent controller / driver P board with the stepper motor. The RV-S can be used in two distinct modes; Stand lone-mode where external programs can be downloaded directly in the controller s PROM memory, and irect-mode where the controller acts as a slave board in conjunction with a master external control system. (More details on operating modes on page 6). low Switching onfigurations and Part Numbers low configurations xial port 4 1 xial port xial port Part nos. Valve version 4 port switching 4-way selection / distribution Valve head assy. (page 4) Valve w/motor (page 5) Valve w/motor and controller (page 6) pplications io-hem luidics lectric Rotary Valves are typically used in one of two main applications; fluid selection/distribution applications where either one stream is diverted to one of multiple ports or multiple streams are diverted to one outlet, and sample injection applications where the valve can be used to load and inject fluids into a sample loop in two discrete steps. luid Selection/istribution Sample Injection io-hem luidics lectric Rotary Valves used as selection / distribution valves allow for accurate and repeatable flow redirection. One input can be diverted to any one of multiple outlets, or, multiple separate inputs can be diverted to one common outlet. One input... 4-way combination 6 port switching 6-way selection / distribution RV-N0-J4-PTN RV-N0-S4-PTN RV-N0-N4-PTN RV-N0-J6-PTN RV-N0-S6-PTN RV-SN2-J4-PTN RV-SN2-S4-PTN RV-SN2-N4-PTN RV-SN2-J6-PTN RV-SN2-S6-PTN RV-S2-J4-PTN RV-S2-S4-PTN RV-S2-N4-PTN RV-S2-J6-PTN RV-S2-S6-PTN io hem luidics switching rotary valves can be used as sample injection valves for analytical systems. They can facilitate loading of a liquid sample into a loop, and injecting the sample into an analysis module. This is especially useful in low-pressure chromatography and Life Science applications. 6 1 Step 1 - the sample can be loaded into the sample loop while the mobile phase is pumped directly 5 2 through to the column. sample loop column sample in...diverted to one of multiple outlets Load 4 3 sample waste Multiple inputs... Step 2 - when the valve switches to the inject position, the pump connects to the sample loop and the sample is carried onto and through the column. The sample in and waste ports are joined but are isolated from the loop. sample loop column sample in...diverted to one outlet Inject 4 3 sample waste

62 4 RV- Series LTRI ROTRY VLVS - (Valve head assembly - no motor) conomic PT/PT Rotary Valve option for OM clients with knowledge and experience with mounting their own stepper motors. Inert flow path - only the PT valve body and PT rotor are in contact with the fluid 1/4-28 UN, flat bottomed fluid connection ports with stainless steel threaded inserts for extra strength and durability two-channel optoelectronic position sensor and optical encoder disc are incorporated into the valve. This position sensor allows for referencing the home position after the unit is powered up and for signalling that the valve has reached a valid port position Incorporates an internal coupling that mates the valve s rotor to the driving source Mounting dimensions fit NM 17 stepper motors Part number 4 port switching RV-N0-J4- PTN Valve specifications 4 port valve 6 port valve 4-way selection / distribution RV-N0-S4- PTN 4-way Selection Valve Head ssembly 4-way combination RV-N0-N4- PTN 6 port switching RV-N0-J6- PTN 6-way selection / distribution RV-N0-S6- PTN Operating pressure (max) 200 psi (13.6 bar) 150 psi (10.3 bar) low path/orifice diameter/v* (1.32mm) / (1.32mm) / Internal volume** 19.5 μl 21.2 μl 19.6 μl 19.4 μl 22.2 μl Weight 100g * nominal v value at 100 psi (13 bar). v value may differ at different pressures. **one complete path [6.6] View on Z View on X xial port M3 x (N4, S tapped hole [31.0] [5.6] & S6 only) [42.4] (3x) 0.68 [17.3] 0.68 [17.3] 1.22 [31.0] Z Ø1.25 [31.8] X 0.39 [9.9] 1.81 [46.0] 0.79 [20.1] 0.34 [8.6] 0.94 ± 0.04 [24.0 ± 1.0] 0.79 [20.0] Wire egress from optical encoder Ø / [ /-0.05] Y 0.85 [21.5] 0.14 [3.5] ccess port / drain Ø0.24 / [6.1] 1/4-28 ports Ø1/8 / [3.2] mounting thru holes, Ø0.23 / [5.8] 0.16 / [4.1] (4x) im im im J4 2.05/ / /13.9 S4 2.17/ / /13.9 N4 2.17/ / /13.9 J6 2.05/ / /19.3 S6 2.34/ / / [4.5] 0.08 Ø0.20 [2.0] [5.0] Recommended motor shaft dimensions 0.79 [20.0] 0.39 [10.0] Notes: 1. ll dims inches / [mm] 2. Ports have stainless steel threaded inserts RV-N lectric Rotary Valve M3 x tapped hole [12.5] (3x) View on Y

63 5 RV-SN Series LTRI ROTRY VLVS - (Valve with motor) lectric Rotary Valve close-coupled to industry standard two-phase, hybrid stepper motor ll valve features as shown on page 4 Trinamic QMOT Stepper motor Motor features: 1.8 step angle Optimized for microstep operation 4 wire connection Neodymium magnets for maximum torque Valve functionality details: Life of assembly - up to 1,000,000 port-to-port cycles Port-to-port move time ms Maximum duty cycle (recommended) % 4 Port Switching Valve with Motor Motor specifications 4 port valve 6 port valve 4 port switching 4-way selection / distribution 4-way combination 6 port switching 6-way selection / distribution Part number RV-SN2-J4- PTN RV-SN2-S4- PTN RV-SN2-N4- PTN RV-SN2-J6- PTN RV-SN2-S6- PTN Motor part number QSH Rated voltage 5.0V Rated phase current 1.0 Phase resistance 5.0v Ω Phase induction 8.0 mh Holding torque 49 cn. m / 69 oz. in Weight (motor & valve) 475g View on X xial port M3 x 0.5 (N4, S tapped hole & S6 only) [42.4] (3x) 0.68 [17.3] 0.68 [17.3] Ø1.25 [31.8] X 0.39 [9.9] 1.81 [46.0] 0.79 [20.1] Wire egress from optical encoder Wire egress from motor Y 0.85 [21.5] 0.14 [3.5] 1/4-28 ports im im im J4 3.90/ / /13.9 S4 4.02/ / /13.9 N4 4.02/ / /13.9 J6 3.90/ / /19.3 S6 4.20/ / /19.3 ccess port / drain Ø0.24 / [6.1] View on Y 0.49 [12.5] M3 x 0.5 tapped hole (3x) 0.39 [10.0] RV-SN lectric Rotary Valve [20.0] Notes: 1. ll dims inches / [mm] 2. Ports have stainless steel threaded inserts

64 6 RV-S Series LTRI ROTRY VLVS - (Valve with motor and controller P) lectric Rotary Valve close-coupled to industry standard two-phase, hybrid stepper motor with intelligent motor controller and driver Valve and motor features as pages 4 & 5 Trinamic PNdrive Motor controller and driver ontroller features: P-based software development environment (Trinamic I) High level commands RS-232 communications protocol On board PROM for stand-alone operation Modes of operation: Stand-alone In Stand-alone mode the controller is used to provide operating signals to the valve from programs downloaded into the on-board PROM memory. The end-user has the option to start the programs automatically with poweron (uto-start ON) or to have them start upon receiving an 6 Port Switching Valve with Motor & ontroller external trigger (uto-start O). irect mode In irect mode commands from a master controller are issued one-at-a-time to the valve controller which is operating as a slave unit only. lthough the valve controller is still responsible for sending signals to the valve, it retains no instructions on-board. Note: Part numbers are the same for both modes of operation. Part number Motor part number ontroller / drive module part no. Weight (motor, valve & controller) 4 port switching RV-S2-J4- PTN 4 port valve 6 port valve 4-way selection / distribution RV-S2-S4- PTN 4-way combination RV-S2-N4- PTN QSH P g 6 port switching RV-S2-J6- PTN 6-way selection / distribution RV-S2-S6- PTN View on X xial port M3 x 0.5 (N4, S tapped hole & S6 only) [42.4] (3x) 0.68 [17.3] 0.68 [17.3] Ø1.25 [31.8] X 0.39 [9.9] 1.81 [46.0] 0.79 [20.1] Wire routes along bottom of motor to P Y 0.85 [21.5] 0.14 [3.5] 1/4-28 ports im im im J4 4.60/ / /13.9 S4 4.72/ / /13.9 N / / /13.9 J6 4.60/ / /19.3 S6 4.90/ / /19.3 ccess port / drain Ø0.24 / [6.1] View on Y 0.49 [12.5] M3 x 0.5 tapped hole (3x) Notes: 1. ll dims inches / [mm] 2. Ports have stainless steel threaded inserts RV-S lectric Rotary Valve [10.0] 0.79 [20.0]

65 7 The io-hem luidics rand MILY io-hem luidics is dedicated to providing instrument manufacturers and laboratories with the industry s best choice of inert, miniature fluid handling components. Under the io-hem Valve brand name we offer a complete fluid system solution for a wide range of industries including analytical chemistry, clinical diagnostics and medical device manufacturers as well as the scientific community. Inert solenoid VLVS and pumps, electric rotary VLVS micro-pumps Isolation valves flow selection VLVS pinch valves electric rotary VLVS manifold assemblies accessories customiztion SRVIS Trademarks Trinamic is a registered trademark of TRINMI Motion ontrol GmbH & o. KG. io-hem Valve is a trademark of io-hem luidics Inc.

66 0.57 [14.5mm] oolube hit and hold circuit TURS Provides a hit and hold circuit for solenoid valves by stepping down voltage Reduces power consumption (Wattage) while in the hold setting Overdrive function permits faster response time Turns valve off immediately when power is cut to the circuit Terminal pins permit easy installation an be mounted directly to most io-hem Valve 075 and 100 series solenoid valves specifications Series coolcube-r coolcube-50r Time from hit to hold voltage: 100 ms 100 ms Input voltage step down to: 1/3 1/2 Max input voltage: 36 V 36 V Max input current: 1 amp 1 amp Hold voltage with 36 V input: 12 V 18 V Hold voltage with 24 V input: 8 V 12 V Hold voltage with 12 V input: 4 V 6 V Power consumption reduction to: 1/9 1/4 dimensions Voltage Step-down unction The compact oolube solenoid control modules provide an easy way to achieve a hit and hold circuit independent of the rated voltage. When a oolube is connected between a solenoid valve and a power supply, it delivers a pulse width modulated (PWM) step-down function. It accepts a range of inputs from 12 to 36 V and passes the input on to energize the solenoid valve with full power for 100ms. fter 100ms, the oolube drops the voltage and current to a level sufficient to hold the solenoid in the energized position. The benefits are less power consumption and lower heat generation. The oolube can remain under power indefinitely without being damaged. When the power to the oolube is cut, the valve is turned off immediately, as though the oolube was not in the system. Overdrive unction 0.75 [19.1mm] The oolube enables an overdrive voltage to be placed on a solenoid valve. This means that a solenoid valve rated for 12 V or 24 V can be energized with a voltage as high as 36 V. Since the oolube automatically drops the voltage after 100ms, the solenoid will not be impaired in any way. The benefits of this are: [0.5mm] round pins Trademarks: io-hem Valve and oolube are trademarks of io-hem luidics Inc. MP is a trademark of Tyco lectronics orporation Molex is a trademark of Molex Incorporated [5.1mm] 1.25 [31.8mm] minimum clearance required 0.65 [16.5mm] aster response time - the valve opening response time can be decreased by up to 60%. Increased pressure rating - the operating pressure rating can be dramatically increased*. Pinch valve tubing - allows the use of larger tubing and / or custom tubing material*. * Requires additional valve customization. Please contact io-hem luidics to discuss your custom requirements.

67 installation instructions Solenoid Valve oolube - Load Input + Return (Neg.) - Relay ontact or Switch + 12 to 36 V + Power Supply Note: lways connect with power off. 1. Using an MP, Molex or similar connector, connect the oolube to the power supply. aution: Note the polarity indicated on the input side of the oolube. If power is reversed, the unit will not function correctly and the chip set may be damaged. 2. Using an MP, Molex or similar connector, connect the valve lead wires to the oolube. No polarity to the solenoid coil is required. 3. Turn on the power supply. aution: do not turn on the power supply before the oolube is connected to the valve. * onnectors are available with 15 of 26 WG PT coated wire as P/N LW-2 for the input pins and the load pins. oolube installed on a typical 100P2N pinch valve (shown with Molex connector) Ordering Information: Part Number OOLU-50R OOLU-R an be used with: ll io-hem Valve solenoid valve products ll io-hem Valve solenoid valve products, except 038, 039 and 040 series isolation valves and quiet type pinch valves

68 Mounting Options io-hem luidics offers four different ways to mount your solenoid operated valve or pump in your instrument. ll four styles can be used across the range of io-hem Valve solenoid operated valves and pumps and are designed to be installed with minimum tooling or effort. MU-Series Mounting lange MR-Series Mounting Ring M-Series Mounting lip Integral Mounting Holes ulkhead Mount Wall Mount ase Mount Mu-series mounting flange onstructed from sturdy, glass-filled Polypropylene Spring steel retainer ring and set screw ensure a secure fit Surface withstands alcohol, bleaches and other common cleaning agents Screw hole orientation relative to tubing can be adjusted to fit available system space Mc-series mounting clip onstructed from Spring Steel Simple construction - no tools required to secure valve into position Holds valve securely inside instrument MR-series mounting ring integral mounting holes onstructed from luminum Tightening screw secures ring firmly to valve but can be loosened for re-positioning an be bulkhead mounted, inside or outside Screw hole orientation relative to tubing can be adjusted to fit available system space Threaded mounting holes in the base of the valve or pump provide a more permanent way to mount directly to a plate or base Order mounting holes by adding the suffix M to the standard part number