98 동방하이테크상사 T.(02) F.(02)

Transcription

1 98 동방하이테크상사 T.(0)57-69 F.(0)

2 troduction to Upchurch Scientific Valves Valves troduction Valves jection and Selection Valves for Pressures to,000 psi (69 bar) Switching and Shut-Off Valves for Pressures to 500 psi ( bar) Directly Connect /6 or /8 OD Tubing with Flangeless Fittings (included) Manual and Actuated Versions Upchurch Scientific Valves are available for /6 or /8 OD tubing in sample injection or six-way flow selection versions. These valves have completely biocompatible flow paths and are perfect for systems where the pressure does not exceed 500,000 psi ( 69 bar), including flow injection analysis (FIA) and some chromatography applications. These valves come in manual (with or without a bulkhead mounting option) and electronically actuated versions. For more details on these valves, please see pages The Valve series also includes our (rated to 500 psi, bar) which offer several options for directional flow control. The most popular is the L style a two-way switching valve that could be used for mobile phase, column or detector selection between two inlets or outlets. Use the T style valve with a plug to change a three-way open connection to a two-way selection valve. The D style valve is a two position four-way switching valve where adjacent ports are connected by a flow path which rotates 90 to change position. Applications for this valve include protection of column or other sensitive instrument components during a cleaning cycle. These biocompatible four-port switching valves are available for manual control or mounted onto an electronic actuator. Polymer inline shut-off valves are also available for /8 or /6 OD tubing to quickly turn a flow stream on or off. For more information on medium-pressure Switching and Shut-Off valves, please see pages 0 0. Micro-Metering and Micro-Splitter Needle Valves Fine Control of Flow in Two-way or Three-way Valves Applicable to a Wide Range of Applications, including terfacing LC/MS Systems Ability to Adjust and Change Split Flow Ratio Versions for Capillary up to /8 OD Tubing Upchurch Scientific Needle Valves control flow of either the output of a two-port valve (Micro-Metering) or on the split stream of a three-port valve (). Use one of these valves to regulate gas flow in a helium sparging system or to split post-column flow to a mass spectrometer. Several versions are available for connecting different tubing sizes, and biocompatible equivalents of each are offered. For more information on the different valve styles and functions, please see pages Electronic Actuators With Factory Premounted Valve Safety Tested and Rated to Conform to ETL, CSA, and CE Specifications All of our valves listed on pages 0 0 are available premounted on compact Electronic Actuators to automate valve positioning. Our valves are coupled with a DC gear motor which offers outstanding rotational accuracy and low actuation times. Upchurch Scientific actuated valves can be conveniently operated by keypad or computer controlled through contact closure and RS- communication. LED indicators on the actuator keypad specify valve position. Additionally, valves may be multiplexed (daisy-chained) for custom automation solutions when using RS- communication. Each actuator is provided with an inline power adapter which allows operation from both 0/0V (North American) and 0/0V (European) AC power. All actuators come with a one-year parts and labor warranty. DC Gear Motor Actuated Valves The user s guide, shipped with each actuated valve, is also available online: DC Gear Motor Actuator Valves User Guide at Prime/Purge Valves Upchurch Scientific also offers two styles of pump Prime/Purge Valves, one for use with Waters HPLC instruments and a universal low pressure version. Both feature easy, luer-actuated operation, and are on page 06. Actuator dimensions, excluding valve (H x W x D): 7mm x 56mm x 65mm (.8 x. x 6.5 ) Actuators cannot be purchased separately they are only available custom programmed for the appropriate premounted valve. Please contact Upchurch Scientific for information on optional stepper motor actuators. Order Tel: /

3 jection Valves jection Valves Biocompatible and ert Low Swept Volume Minimal Dispersion Upchurch Scientific 6-Port jection Valves feature easy, external sample loop customization. Simply clean-cut a piece of tubing that represents the volume of sample you wish to inject, taking into account the port-to-port volume of the valve. Please refer to the Tubing ternal Diameters and Volumes chart on page 7 for assistance in calculating the volume of a length of tubing. Two biocompatible injection valve options are available: Long-Life Ceramic Featuring ceramic-to-ceramic sealing surfaces, these new long-life valves have been tested to over one million actuations with no change in performance.* The wetted materials are chemically resistant ceramic and PEEK polymer and the valves are rated to 500 psi ( bar). Each valve includes /-8 Flangeless Fittings for /6 OD tubing. Economical Polymer These economical valves have chemically resistant Vespel and DuPont Teflon brand resin wetted surfaces and are rated for a maximum pressure of,000 psi (69 bar). Each valve includes /-8 Flangeless Fittings for /6 or /8 OD tubing. Both valve options are available in three configurations: standard manual, bulkhead mountable manual and actuated. A valve mounting bracket (M-65-) is listed on page 0, and bulkhead mounting specifications are available at Refer to page 99 for information regarding the DC Gear motor actuators. Please contact Upchurch Scientific for stepper motor actuated options, as well as custom configurations for instrument manufacturers. High pressure injection valve options are available starting on page 78. * Tested using room-temperature water as the solvent. jection Port Adapter Our simple, biocompatible adapter converts any /-8 flat-bottom port into a port that can accept a standard gauge HPLC injection needle. This injection port adapter is adjustable, so you can create a snug fit around the needle to prevent any leaking of the analyte. addition, this product features an internal stop that prevents you from inserting the needle too far, eliminating the possibility of damaging the valve with the needle tip. P-96 Replaceable Tubing and Ferrule Assembly (cluded) V-6-DC Viewpoint from rotary knob Pump Sample (Needle Port) Pump Position A (LOAD) V-5-DC Flow path of jection Valve (highlighting flow through sample loop in each position) jection Valves, manual M-60 jection Valve, Ceramic, for /6 OD tubing.00 thru-hole, 6.9µL swept volume, Black M-6 Bulkhead version of M-60 V-50 jection Valve, Polymer, for /6 OD tubing.00 thru-hole, 5.µL swept volume, Black V-5 Bulkhead version of V-50 V-50 jection Valve, Polymer, for /8 OD tubing.06 thru-hole,.7µl swept volume, Red V-5 Bulkhead version of V-50 V-0 5/6 Allen Wrench (replacement) Sample Waste 5 Position B (INJECT) jection Valves, actuated V-5 Manual Valve Dimensions (excluding fittings) Valve Type Sealing Surfaces Dimensions (L x W) Standard Bulkhead Mountable Polymer Ceramic Polymer Ceramic Width of the knob, which is slightly wider than the valve body..7 x. (69. x.5 mm).75 x.0 (69.8 x.0 mm).9 x. (7. x.5 mm).00 x.0 (76. x.0 mm) Sample (Needle Port) Sample Waste 00 Adapter Body P-95 jection Port Adapter Needle Port Order Tel: / V-5-DC Actuated version of V-5, DC Gear (premounted) V-5-DC Actuated version of V-5, DC Gear (premounted) V-6-DC Actuated version of M-6, DC Gear (premounted) jection Port Adapter P-95 Adjustable jection Port Adapter P-96 Replacement Tubing/Ferrule Assembly Comes complete with P-5/P-00 Flangeless Fittings. Per pathway. Three pathways per valve. Comes complete with P-5/P-0 Flangeless Fittings. Actuated valves also include: () serial port adapter; () each RS- and contact closure communications cables; () power adapter; () each North American style and European style power cord. DC gear actuated valves come with a communication cable for multiplex (daisy-chain) operations.

4 Selection Valves V--DC V-7-DC 6-Way Selection Valves Biocompatible and ert Low Swept Volume Excellent Choice for Mobile Phase Selection Patented Upchurch Scientific 6-Way Selection Valves have a common inlet (or outlet) port connected to six different ports. Use these valves to select between multiple solvent reservoirs without having to disconnect and reconnect lines (see Application Note). Or, use two valves in conjunction with each other to serve as a column selection system in a moderate pressure semi-prep or high-flow analytical application. These ceramic valves are ideal for biocompatible instrumentation and can be used in flash chromatography for the preparation of proteomics samples. Two biocompatible selection valve options are available: V-0 Long-Life Ceramic Featuring ceramic-to-ceramic sealing surfaces, these new long-life valves have been tested to over one million actuations with no change in performance.* The wetted materials are chemically resistant ceramic and PEEK polymer and the valves are rated to 500 psi ( bar). Each valve includes /-8 Flangeless Fittings for /6 OD tubing. Use our 6-Way Selection Valve to easily select different solvents with an isocratic pump. The setup below involves an isocratic pump used for two separate assays, each requiring a prerinsing step prior to use. Using our Selection Valve in this setup, the system can be primed with the solvent in the first reservoir. Then, solvent from the second reservoir can be used as the mobile phase for the first application. Later, the system can be rinsed with an intermediate buffer solution from the third reservoir, followed by switching over to the second mobile phase in reservoir number. At the end of the day, the system can be rinsed with water from a fifth reservoir to avoid the possibility of precipitation on wetted surfaces. Follow this rinse with a final rinse of methanol from the sixth reservoir for system storage. # Mobile Phase 6-Way Valve # Priming Solution Economical Polymer These economical valves have chemically resistant Vespel and DuPont Teflon brand resin wetted surfaces and are rated for a maximum pressure of,000 psi (69 bar). Each valve includes /-8 Flangeless Fittings for /6 or /8 OD tubing. If your application does not require all six outer ports, seal the extra port(s) with any flat-bottom /-8 plug from page 60. Both valve options are available in three configurations: standard manual, bulkhead mountable manual and actuated. A valve mounting bracket (M-65-) is listed on page 0, and bulkhead mounting specifications are available at Refer to page 99 for information regarding the DC Gear motor actuator. Dimensions of the manual selection valves are the same as that of the injection valves please refer to the dimensions chart on page 00. Please contact Upchurch Scientific for stepper motor actuated options, as well as custom configurations for instrument manufacturers. High pressure selection valve options are available starting on page 78. * Tested using room-temperature water as the solvent. # termediate Buffer Solution # Mobile Phase Isocratic Pump #5 Rinse Water #6 MeOH Sample jection Valve 6-Way Selection Valves, Manual M-70 6-Way Selection Valve, Ceramic, for /6 OD tubing.00 thru-hole, 6.µL swept volume, Black M-7 Bulkhead version of M-70 V-0 6-Way Selection Valve, Polymer, for /6 OD tubing.00 thru-hole,.5µl swept volume, Black V- Bulkhead version of V-0 V-0 6-Way Selection Valve, Polymer, for /8 OD tubing.06 thru-hole, 8.µL swept volume, Red V- Bulkhead version of V-0 V-0 5/6 Allen Wrench (replacement) Waste medium Pressure 6-Way Selection Valves, actuated Data Recording Device V--DC Actuated version of V-, DC Gear (premounted) V--DC Actuated version of V-, DC Gear (premounted) V-7-DC Actuated version of V-7, DC Gear (premounted) Comes complete with P-5/P-00 Flangeless Fittings. Comes complete with P-5/P-0 Flangeless Fittings. Actuated valves also include: () serial port adapter; () each RS- and contact closure communications cables; () power adapter; () each North American style and European style power cord. DC gear actuated valves come with a communication cable for multiplex (daisy-chain) Order Tel: / operations. 0

5 Switching and Shut-Off Valves -Port Shut-Off Valves Switching Valve Applications With three versions to choose from, Upchurch Scientific Switching Valves offer many flow distribution options. Each valve has a low swept volume, can withstand pressures to 500 psi ( bar) and is chemically inert and biocompatible. The PEEK and DuPont Teflon brand resin construction results in a valve as durable as it is economical. Each V-00 Series Switching Valve has.00 thru-holes and is supplied with Flangeless Fittings for use with /6 OD tubing. To use these valves with /8 OD tubing, simply replace the supplied fittings with /-8 Flangeless Fittings found on page 57. You may notice a slight back pressure at higher flow rates, due to the.00 thru-holes in these valves. Protect sensitive system components (such as a column) during a cleaning cycle with our Diagonal Flow Switching Valve ( D ). This valve eliminates the need to remove, plug and reconnect a low pressure column (see below). Pump To operate, all ports must be either connected to a line of your system or plugged. Built-in positioning detents allow these valves to snap into place, ensuring the thru-hole is properly aligned. V-0D-DC Position Each of the Upchurch Scientific -Port is available in standard manual and bulkhead mountable manual configurations. Bulkhead mounting specifications are included and are also available at The bulkhead mountable manual configuration can also be mounted on our M-65- Valve Bracket (see below). DC gear motor actuated versions are also available please see page 0 for actuator information. Selected applications for our are listed on the following page. However, there are also several other possible uses for these valves. Please contact your local authorized Distributor or Upchurch Scientific directly to discuss your particular application. Valve Brackets Mount the bulkhead mountable manual valves presented on pages 00 0 with these Brackets. Once mounted, a valve will be positioned horizontally. Extra holes are provided for valve accessories. Made of sturdy anodized aluminum, these brackets can be attached to any lab surface. Each bracket comes with the required valve mounting hardware and instructions. -Way Diagonal Flow (V-00D, V-0D, V-0D-DC) Right Angle Flow (V-00L, V-0L, V-0L-DC) -Way Flow (V-00T, V-0T, V-0T-DC) Swept Volume V-00D -Way Diagonal Flow Switching Valve.µL V-00L Right Angle Flow Switching Valve 6.µL V-00T -Way Flow Switching Valve V-0D Bulkhead Version of V-00D.µL V-0L Bulkhead Version of V-00L 6.µL V-0T Bulkhead Version of V-00T V Allen Wrench (replacement) Swept Volume V-0D-DC Actuated version of V-0D,.µL V-0L-DC Actuated version of V-0L, 6.µL V-0T-DC Actuated version of V-0T, Valve Bracket.9 shown with an M-6 jection Valve (not included) 0 Order Tel: / V-00L Valve # M-65- M-65- Mounting Bracket for (this page) Mounting Bracket for jection and Selection Valves (pages 0 0) Comes complete with P-8BLK/P-0 Flangeless Fittings. L and T valve versions also include a P-09 Plug. Actuated valves also include: () serial port adapter; () each RS- and contact closure communications cables; () power adapter; () each North American style and European style power cord. DC gear actuated valves come with a communication cable for multiplex (daisy-chain) operations..5 diameter.07 V-00L Valve # # Plug switching application may require the flexibility of routing the column effluent to both detectors simultaneously while retaining the ability to isolate each detector. Use our -Way Flow Switching Valve ( T ), plugging off the fourth port with the included plug (see right). # Plug Position P-7 PEEK Shut-Off Valve.50 P-78 ETFE Shut-Off Valve Position Your detector Medium pressure -Port, Actuated M-65- Valve Bracket, Medium pressure -Port, Manual.0 Position A typical application for a Right Angle Flow Switching Valve ( L ) is column switching, allowing two columns to use one detector. switching is another common application for this valve (see below). Plug off the extra port with the included plug. Switching Valve Options: Please contact Upchurch Scientific for stepper motor actuated options, as well as custom configurations for instrument manufacturers. High pressure switching valve options are available starting on page 78. Connect semi-rigid or rigid tubing, such as PEEK, stainless steel or DuPont Teflon brand resin, with the /-8 Flangeless Fittings provided. Soft tubing, such as Pharmed or Tygon (see pages ), may be connected to these valves using our /-8 barbed adapters, found on page 8. n lum Co n lum Co V-0L Standard manual valves (V-00D, V-00L and V00T) measure.80 (5.7 mm) in length. Bulkhead versions (V-0D, V-0L and V-0T) are.8 (55. mm) long.. Pump Stop a flow stream quickly with Upchurch Scientific biocompatible Shut-Off Valves. The bodies are manufactured from either PEEK or Tefzel (ETFE) with a Kel-F rotor, making them highly resistant to chemical attack. The blue colorant used in some valve configurations has proven not to leach out with common HPLC solvents. Three Flow Configurations to Choose From Biocompatible Flow Paths For Applications Biocompatible, All-Polymer Flow Path Available for /6 and /8 OD Tubing # # Position stall a Shut-Off Valve between the solvent reservoir and pump. Then, when it is necessary to disconnect the solvent line, a simple twist of the valve lever eliminates the potential of a hazardous spill. # # Position Shut-Off Valves # ternal Material OD Tubing Thru-hole Volume P-7 PEEK, Natural /6.00.5µL P-7 PEEK, Natural / µL P-78 ETFE, Blue /6.00.5µL P-78 ETFE, Blue / µL P-7 ETFE, Natural / µL # Position Maximum internal volume, with valve fully open. Comes complete with P-5/P-00 Fittings. Comes complete with P-5/P-00 Fittings. Comes complete with P-5/P-00N Fittings. Pressure Rating 500 psi ( bar) 500 psi ( bar) 500 psi ( bar) 500 psi ( bar) 500 psi ( bar) Order Tel: /

6 Switching and Shut-Off Valves -Port Shut-Off Valves Switching Valve Applications With three versions to choose from, Upchurch Scientific Switching Valves offer many flow distribution options. Each valve has a low swept volume, can withstand pressures to 500 psi ( bar) and is chemically inert and biocompatible. The PEEK and DuPont Teflon brand resin construction results in a valve as durable as it is economical. Each V-00 Series Switching Valve has.00 thru-holes and is supplied with Flangeless Fittings for use with /6 OD tubing. To use these valves with /8 OD tubing, simply replace the supplied fittings with /-8 Flangeless Fittings found on page 57. You may notice a slight back pressure at higher flow rates, due to the.00 thru-holes in these valves. Protect sensitive system components (such as a column) during a cleaning cycle with our Diagonal Flow Switching Valve ( D ). This valve eliminates the need to remove, plug and reconnect a low pressure column (see below). Pump To operate, all ports must be either connected to a line of your system or plugged. Built-in positioning detents allow these valves to snap into place, ensuring the thru-hole is properly aligned. V-0D-DC Position Each of the Upchurch Scientific -Port is available in standard manual and bulkhead mountable manual configurations. Bulkhead mounting specifications are included and are also available at The bulkhead mountable manual configuration can also be mounted on our M-65- Valve Bracket (see below). DC gear motor actuated versions are also available please see page 0 for actuator information. Selected applications for our are listed on the following page. However, there are also several other possible uses for these valves. Please contact your local authorized Distributor or Upchurch Scientific directly to discuss your particular application. Valve Brackets Mount the bulkhead mountable manual valves presented on pages 00 0 with these Brackets. Once mounted, a valve will be positioned horizontally. Extra holes are provided for valve accessories. Made of sturdy anodized aluminum, these brackets can be attached to any lab surface. Each bracket comes with the required valve mounting hardware and instructions. -Way Diagonal Flow (V-00D, V-0D, V-0D-DC) Right Angle Flow (V-00L, V-0L, V-0L-DC) -Way Flow (V-00T, V-0T, V-0T-DC) Swept Volume V-00D -Way Diagonal Flow Switching Valve.µL V-00L Right Angle Flow Switching Valve 6.µL V-00T -Way Flow Switching Valve V-0D Bulkhead Version of V-00D.µL V-0L Bulkhead Version of V-00L 6.µL V-0T Bulkhead Version of V-00T V Allen Wrench (replacement) Swept Volume V-0D-DC Actuated version of V-0D,.µL V-0L-DC Actuated version of V-0L, 6.µL V-0T-DC Actuated version of V-0T, Valve Bracket.9 shown with an M-6 jection Valve (not included) 0 Order Tel: / V-00L Valve # M-65- M-65- Mounting Bracket for (this page) Mounting Bracket for jection and Selection Valves (pages 0 0) Comes complete with P-8BLK/P-0 Flangeless Fittings. L and T valve versions also include a P-09 Plug. Actuated valves also include: () serial port adapter; () each RS- and contact closure communications cables; () power adapter; () each North American style and European style power cord. DC gear actuated valves come with a communication cable for multiplex (daisy-chain) operations..5 diameter.07 V-00L Valve # # Plug switching application may require the flexibility of routing the column effluent to both detectors simultaneously while retaining the ability to isolate each detector. Use our -Way Flow Switching Valve ( T ), plugging off the fourth port with the included plug (see right). # Plug Position P-7 PEEK Shut-Off Valve.50 P-78 ETFE Shut-Off Valve Position Your detector Medium pressure -Port, Actuated M-65- Valve Bracket, Medium pressure -Port, Manual.0 Position A typical application for a Right Angle Flow Switching Valve ( L ) is column switching, allowing two columns to use one detector. switching is another common application for this valve (see below). Plug off the extra port with the included plug. Switching Valve Options: Please contact Upchurch Scientific for stepper motor actuated options, as well as custom configurations for instrument manufacturers. High pressure switching valve options are available starting on page 78. Connect semi-rigid or rigid tubing, such as PEEK, stainless steel or DuPont Teflon brand resin, with the /-8 Flangeless Fittings provided. Soft tubing, such as Pharmed or Tygon (see pages ), may be connected to these valves using our /-8 barbed adapters, found on page 8. n lum Co n lum Co V-0L Standard manual valves (V-00D, V-00L and V00T) measure.80 (5.7 mm) in length. Bulkhead versions (V-0D, V-0L and V-0T) are.8 (55. mm) long.. Pump Stop a flow stream quickly with Upchurch Scientific biocompatible Shut-Off Valves. The bodies are manufactured from either PEEK or Tefzel (ETFE) with a Kel-F rotor, making them highly resistant to chemical attack. The blue colorant used in some valve configurations has proven not to leach out with common HPLC solvents. Three Flow Configurations to Choose From Biocompatible Flow Paths For Applications Biocompatible, All-Polymer Flow Path Available for /6 and /8 OD Tubing # # Position stall a Shut-Off Valve between the solvent reservoir and pump. Then, when it is necessary to disconnect the solvent line, a simple twist of the valve lever eliminates the potential of a hazardous spill. # # Position Shut-Off Valves # ternal Material OD Tubing Thru-hole Volume P-7 PEEK, Natural /6.00.5µL P-7 PEEK, Natural / µL P-78 ETFE, Blue /6.00.5µL P-78 ETFE, Blue / µL P-7 ETFE, Natural / µL # Position Maximum internal volume, with valve fully open. Comes complete with P-5/P-00 Fittings. Comes complete with P-5/P-00 Fittings. Comes complete with P-5/P-00N Fittings. Pressure Rating 500 psi ( bar) 500 psi ( bar) 500 psi ( bar) 500 psi ( bar) 500 psi ( bar) Order Tel: /

7 Micro-Splitter Valve Applications & Notes Upchurch Scientific offers a line of Micro-Splitter Needle Valves designed to accurately split and control a low-flow stream off a single incoming supply. P-70 The biocompatible are perfect for LC-MS and other multidetector systems and fraction collectors. The ideal placement of these valves is on the effluent side of the detector flow cell, at a maximum pressure of. Choose between /-8 and 0- threaded versions. A valve is also available to accommodate applications involving capillary tubing. M-05S The High Pressure are designed to operate under pressures up to,000 psi (76 bar). These products are well suited for running two analytical devices in parallel. The High Pressure Capillary may also be used to adapt an analytical HPLC system to handle microbore applications. P-50 Our Graduated Valves offer many of the benefits and features of our original, plus the ability to adjust and set the split flow to repeatable settings. This allows documentation of settings and the resulting flow rates for easier method development. The graduations also make it easier to employ the valve in a system used to run multiple analyses that require different split flow rates. Choose from regular High Pressure and Capillary versions. All have been tested at flow rates to 00mL/min., with a maximum resulting pressure drop of only 5 psi (. bar). his valve has a MicroTight 6- threaded fitting on the split stream. Select the appropriately sized T MicroTight Tubing Sleeve from page 8 to connect your capillary tubing. Preasure drop measured when valves fully opened. P-5 Micro-Splitter Valve Thumbscrew Back Pressure Considerations Our are designed to work when both effluent flow path pressures are nearly identical. However, the split flow path will often have higher back pressure than the waste flow path, making it hard to achieve any split flow at all. There are two possible solutions. Place a back pressure regulator (see pages 08 0) on the waste flow path that is equal to or slightly greater than the pressure on the split flow path. Or, switch the two effluent pathways such that the split flow pathway is attached to the waste port on the valve and the waste flow pathway is attached to the split port on the valve. This second method may result in a loss of adjustment sensitivity. For fine control of fluid flow rates, our Micro-Metering Needle Valves can reduce outgoing flow to as low as.5µl/min*. These needle valves are perfect for use with peristaltic pump fluid-transfer applications, mass spectrometry, and fraction collection. Upchurch Scientific can also be used to regulate gas flow in helium sparging lines and as a flow-dependent variable back pressure regulator. For flow independent regulation of back pressure, please see pages Please request our Flow Control Valve Applications Guide for more details. Flow path materials are PEEK polymer and Teflon (O-rings). All versions of this valve have.00 thru-holes. *At.0mL/min incoming flow rate with room temperature water. Prime/Purge Valve Micro Splitter Valve formation: ternal Max. Volume Operating (closed/ Pressure Min. Split Valve Type Threads fully open) (psi/bar) Flow Rate P-50 /-8. /. µl µl/min P /.8 µl µl/min P-5 Medium Pres. Capillary 0- / 6-. /. µl µl/min P-60S,T High Pressure 0-. /.8 µl,000 / 76.8µL/min P-70 High Pres. Graduated 0-. /.8 µl,000 / 76.8µL/min M-05S,T High Pres. Capillary 0- / 6-. /. µl,000 / 76.8µL/min M-7 High Pres. Cap. Grad. 0- / 6-. /. µl,000 / 76.8µL/min The supply and waste port thru-holes have IDs of.00. The ID for the split-stream port thruhole is.00 in standard versions; in capillary versions it is.00. All tests conducted at an incoming flow rate of ml/min. using room temperature water, with equal pressures on both effluent streams. Lower incoming flow rates will result in a gradual loss of sensitivity when setting the split rate. Air within the pump head can cause noisy pump operation and flow instability. Solve this problem by placing a High Pressure Micro-Splitter Valve or High Pressure Universal Prime/Purge Valve (page 06) inline between the pump and the injector valve. You can then safely divert pump flow to a waste container at a sufficient rate to dislodge the air. Remove air from the solvent line leading to the pump with a Low Pressure Prime/Purge Valve (page 06). Multi- and Systems M-05S High Pressure Capillary, 0-/6-, with stainless steel needle cludes: () F-0 PEEK Fingertight Fittings for /6 OD tubing and () F-5 PEEK Micro Fingertight for capillary tubing * M-05T High Pressure Capillary, 0-/6-, with titanium needle cludes: () F-0 PEEK Fingertight Fittings for /6 OD tubing and () F-5 PEEK Micro Fingertight for capillary tubing* P-50, /-8, biocompatible cludes: () P-00 Tefzel (ETFE) Ferrules and () P-5 PEEK Flangeless Nuts for /6 OD tubing P-5, 0-, biocompatible cludes: () F-0 PEEK Fingertight Fittings for /6 OD tubing P-5 Capillary, 0-/6-, biocompatible cludes: () F-0 PEEK Fingertight Fittings for /6 OD tubing () F-5 PEEK Micro Fingertight for capillary tubing* P-60S High Pressure, 0-, with stainless steel needle cludes: () F-0 PEEK Fingertight Fittings for /6 OD tubing P-60T High Pressure, 0-, with titanium needle cludes: () F-0 PEEK Fingertight Fittings for /6 OD tubing OUT.7 Does your work require analyses with multiple columns and detectors that use the same mobile phase? If so, install one of our High Pressure after your injector. A single injection can then be split to two separate columns and detector systems, at two different flow rates. This economical set-up eliminates the need for an additional pump and injector valve, while allowing data to be obtained simultaneously. Post- terfacing.0. Flow Rates as Low as.5µl/min* /-8 and 0- Designs Available PEEK Polymer Construction, with DuPont Teflon Brand Resin Seals Use a Micro-Splitter Valve to route fluid exiting an initial detector to other devices, such as a mass spectrometer and a fraction collector. The valve will split and reduce the flow rate to that required for MS interfacing, while diverting the remainder of the flow to the collector (a back pressure regulator may also be required for this set up, available on pages 08 0). Order Tel: / P-70 High Pressure Graduated, 0-, with stainless steel needle cludes: () F-0 PEEK Fingertight Fittings for /6 OD tubing M-7 High Pressure Capillary Graduated, 0-/6-, with stainless steel needle cludes: () F-0 PEEK Fingertight Fittings for /6 OD tubing and () F-5 PEEK Micro Fingertight for capillary tubing* * Use with our MicroTight Tubing Sleeves, found on page 8. IN.9 Thumbscrew.8 P-5 /-8 threaded PEEK Micro-Metering Valve Other Applications See a flow diagram on page 7 of sample purification and concentration that includes use of a Micro-Splitter Valve. These valves are also suited for other applications, such as adapting a standard HPLC system to handle microbore analyses. For more information and plumbing diagrams for this application and those listed above, please request our Flow Control Valve Applications Guide. ternal Material OD Tubing Thru-hole Volume P-5 PEEK, Black / µL P-6 PEEK, Black / µL P-7 PEEK, Black / µL graduated 0 For terfacing LC-MS Systems Adjustable Split Stream Flow Rates Medium and High Pressure Versions Maximum internal volume, with valve fully open. Comes complete with /-8 P-0/P-00 Flangeless Fittings Comes complete with 0- F-0 One-Piece Fingertight Fittings. Comes complete with /-8 P-0/P-00 Flangeless Fittings. Pressure Rating Order Tel: /

8 Micro-Splitter Valve Applications & Notes Upchurch Scientific offers a line of Micro-Splitter Needle Valves designed to accurately split and control a low-flow stream off a single incoming supply. P-70 The biocompatible are perfect for LC-MS and other multidetector systems and fraction collectors. The ideal placement of these valves is on the effluent side of the detector flow cell, at a maximum pressure of. Choose between /-8 and 0- threaded versions. A valve is also available to accommodate applications involving capillary tubing. M-05S The High Pressure are designed to operate under pressures up to,000 psi (76 bar). These products are well suited for running two analytical devices in parallel. The High Pressure Capillary may also be used to adapt an analytical HPLC system to handle microbore applications. P-50 Our Graduated Valves offer many of the benefits and features of our original, plus the ability to adjust and set the split flow to repeatable settings. This allows documentation of settings and the resulting flow rates for easier method development. The graduations also make it easier to employ the valve in a system used to run multiple analyses that require different split flow rates. Choose from regular High Pressure and Capillary versions. All have been tested at flow rates to 00mL/min., with a maximum resulting pressure drop of only 5 psi (. bar). his valve has a MicroTight 6- threaded fitting on the split stream. Select the appropriately sized T MicroTight Tubing Sleeve from page 8 to connect your capillary tubing. Preasure drop measured when valves fully opened. P-5 Micro-Splitter Valve Thumbscrew Back Pressure Considerations Our are designed to work when both effluent flow path pressures are nearly identical. However, the split flow path will often have higher back pressure than the waste flow path, making it hard to achieve any split flow at all. There are two possible solutions. Place a back pressure regulator (see pages 08 0) on the waste flow path that is equal to or slightly greater than the pressure on the split flow path. Or, switch the two effluent pathways such that the split flow pathway is attached to the waste port on the valve and the waste flow pathway is attached to the split port on the valve. This second method may result in a loss of adjustment sensitivity. For fine control of fluid flow rates, our Micro-Metering Needle Valves can reduce outgoing flow to as low as.5µl/min*. These needle valves are perfect for use with peristaltic pump fluid-transfer applications, mass spectrometry, and fraction collection. Upchurch Scientific can also be used to regulate gas flow in helium sparging lines and as a flow-dependent variable back pressure regulator. For flow independent regulation of back pressure, please see pages Please request our Flow Control Valve Applications Guide for more details. Flow path materials are PEEK polymer and Teflon (O-rings). All versions of this valve have.00 thru-holes. *At.0mL/min incoming flow rate with room temperature water. Prime/Purge Valve Micro Splitter Valve formation: ternal Max. Volume Operating (closed/ Pressure Min. Split Valve Type Threads fully open) (psi/bar) Flow Rate P-50 /-8. /. µl µl/min P /.8 µl µl/min P-5 Medium Pres. Capillary 0- / 6-. /. µl µl/min P-60S,T High Pressure 0-. /.8 µl,000 / 76.8µL/min P-70 High Pres. Graduated 0-. /.8 µl,000 / 76.8µL/min M-05S,T High Pres. Capillary 0- / 6-. /. µl,000 / 76.8µL/min M-7 High Pres. Cap. Grad. 0- / 6-. /. µl,000 / 76.8µL/min The supply and waste port thru-holes have IDs of.00. The ID for the split-stream port thruhole is.00 in standard versions; in capillary versions it is.00. All tests conducted at an incoming flow rate of ml/min. using room temperature water, with equal pressures on both effluent streams. Lower incoming flow rates will result in a gradual loss of sensitivity when setting the split rate. Air within the pump head can cause noisy pump operation and flow instability. Solve this problem by placing a High Pressure Micro-Splitter Valve or High Pressure Universal Prime/Purge Valve (page 06) inline between the pump and the injector valve. You can then safely divert pump flow to a waste container at a sufficient rate to dislodge the air. Remove air from the solvent line leading to the pump with a Low Pressure Prime/Purge Valve (page 06). Multi- and Systems M-05S High Pressure Capillary, 0-/6-, with stainless steel needle cludes: () F-0 PEEK Fingertight Fittings for /6 OD tubing and () F-5 PEEK Micro Fingertight for capillary tubing * M-05T High Pressure Capillary, 0-/6-, with titanium needle cludes: () F-0 PEEK Fingertight Fittings for /6 OD tubing and () F-5 PEEK Micro Fingertight for capillary tubing* P-50, /-8, biocompatible cludes: () P-00 Tefzel (ETFE) Ferrules and () P-5 PEEK Flangeless Nuts for /6 OD tubing P-5, 0-, biocompatible cludes: () F-0 PEEK Fingertight Fittings for /6 OD tubing P-5 Capillary, 0-/6-, biocompatible cludes: () F-0 PEEK Fingertight Fittings for /6 OD tubing () F-5 PEEK Micro Fingertight for capillary tubing* P-60S High Pressure, 0-, with stainless steel needle cludes: () F-0 PEEK Fingertight Fittings for /6 OD tubing P-60T High Pressure, 0-, with titanium needle cludes: () F-0 PEEK Fingertight Fittings for /6 OD tubing OUT.7 Does your work require analyses with multiple columns and detectors that use the same mobile phase? If so, install one of our High Pressure after your injector. A single injection can then be split to two separate columns and detector systems, at two different flow rates. This economical set-up eliminates the need for an additional pump and injector valve, while allowing data to be obtained simultaneously. Post- terfacing.0. Flow Rates as Low as.5µl/min* /-8 and 0- Designs Available PEEK Polymer Construction, with DuPont Teflon Brand Resin Seals Use a Micro-Splitter Valve to route fluid exiting an initial detector to other devices, such as a mass spectrometer and a fraction collector. The valve will split and reduce the flow rate to that required for MS interfacing, while diverting the remainder of the flow to the collector (a back pressure regulator may also be required for this set up, available on pages 08 0). Order Tel: / P-70 High Pressure Graduated, 0-, with stainless steel needle cludes: () F-0 PEEK Fingertight Fittings for /6 OD tubing M-7 High Pressure Capillary Graduated, 0-/6-, with stainless steel needle cludes: () F-0 PEEK Fingertight Fittings for /6 OD tubing and () F-5 PEEK Micro Fingertight for capillary tubing* * Use with our MicroTight Tubing Sleeves, found on page 8. IN.9 Thumbscrew.8 P-5 /-8 threaded PEEK Micro-Metering Valve Other Applications See a flow diagram on page 7 of sample purification and concentration that includes use of a Micro-Splitter Valve. These valves are also suited for other applications, such as adapting a standard HPLC system to handle microbore analyses. For more information and plumbing diagrams for this application and those listed above, please request our Flow Control Valve Applications Guide. ternal Material OD Tubing Thru-hole Volume P-5 PEEK, Black / µL P-6 PEEK, Black / µL P-7 PEEK, Black / µL graduated 0 For terfacing LC-MS Systems Adjustable Split Stream Flow Rates Medium and High Pressure Versions Maximum internal volume, with valve fully open. Comes complete with /-8 P-0/P-00 Flangeless Fittings Comes complete with 0- F-0 One-Piece Fingertight Fittings. Comes complete with /-8 P-0/P-00 Flangeless Fittings. Pressure Rating Order Tel: /

9 Prime/Purge Valves Prime/Purge Valve for Waters Pumps Automatic Valve Operation with a Simple Twist of a Luer Lock Syringe No Tubing to Cut or Ferrules to Swage No Wear on the ternal Seal The Upchurch Scientific Prime/Purge Valve for Waters pumps automatically opens when a luer syringe is attached and closes when the syringe is removed. No valve rotation is required after the initial installation, so wear on the internal seal is eliminated. addition, our Waters-compatible Prime/Purge Valve is simpler to operate and more economically priced than alternative valves available for Waters systems. This valve is constructed of rugged materials, including a PEEK valve body. The component structure ensures compatibility with virtually all common solvents used in HPLC analyses. A Waters-compatible internal DuPont Teflon brand resin seal is included with the valve. This seal can also be purchased separately. It can be used both with the Upchurch Scientific valve and the original valve supplied with the pump. Attaching Removing the syringe Automatically Opens and Closes the Valve: Syringe (not included) Universal Prime/Purge Valves For Any Style HPLC System Automatic Luer Syringe Operation Featuring Handy Mounting Holes Upchurch Scientific Universal Prime/Purge Valves are easy to operate. Simply install a valve along the flow path with the included fittings and attach a luer-tipped syringe. Then, withdraw the plunger and watch as solvent and residual bubbles are removed from the solvent line. The valves automatically close when the syringe is removed. The low pressure version of the valve is designed to be used with /8 OD tubing, while the high pressure version accommodates /6 OD tubing. Optional mounting is made easy by the handy holes in the body of each unit. Air in the let Solvent Line stall the Low Pressure Universal Prime/Purge Valve along the inlet solvent path near the pump to remove bubbles from the inlet solvent line. The valve can also be used to rapidly wet your solvent inlet filter. When a new filter is installed, it often contains a substantial amount of air within its pores. At standard flow rates, it may require several minutes before the inlet fluid pathway is completely free of gas. Using this valve you are able to rapidly draw solvent through the inlet filter, dislodging the gas and minimizing downtime. Air in the Pumphead Air within the pumphead can cause flow instability and noisy pump operation. Place the High Pressure Prime/Purge Valve between the pump and the sample injector, where it can be used to remove bubbles that have become lodged within your pump. This valve is rated for a maximum pressure of 5,000 psi (5 bar). Luer Port Check Valve Assembly.8.9 V- Low Pressure Universal Prime/Purge Valve Mounting holes are.75 apart 06 The wetted materials for our Waters-compatible and Universal Prime/Purge Valves are ruby, sapphire, PEEK, Teflon and stainless steel. For another luer check valve option, see the Quick-Stop Luer line Check Valve on page. Order Tel: / Prime/Purge Valves V-0 Prime/Purge Valve for Waters Pumps cludes () V-0-06 Teflon seal V-0-06 Replacement Teflon Seal (for V-0) V- Low Pressure Universal Prime/Purge Valve cludes () P-00N Tefzel Ferrules & () P-5 PEEK Nuts, for /8 OD tubing V- High Pressure Universal Prime/Purge Valve cludes () F-0 Fittings for /6 OD tubing B-0 0cc Disposable Luer-Tipped Syringe

10 Prime/Purge Valves Prime/Purge Valve for Waters Pumps Automatic Valve Operation with a Simple Twist of a Luer Lock Syringe No Tubing to Cut or Ferrules to Swage No Wear on the ternal Seal The Upchurch Scientific Prime/Purge Valve for Waters pumps automatically opens when a luer syringe is attached and closes when the syringe is removed. No valve rotation is required after the initial installation, so wear on the internal seal is eliminated. addition, our Waters-compatible Prime/Purge Valve is simpler to operate and more economically priced than alternative valves available for Waters systems. This valve is constructed of rugged materials, including a PEEK valve body. The component structure ensures compatibility with virtually all common solvents used in HPLC analyses. A Waters-compatible internal DuPont Teflon brand resin seal is included with the valve. This seal can also be purchased separately. It can be used both with the Upchurch Scientific valve and the original valve supplied with the pump. Attaching Removing the syringe Automatically Opens and Closes the Valve: Syringe (not included) Universal Prime/Purge Valves For Any Style HPLC System Automatic Luer Syringe Operation Featuring Handy Mounting Holes Upchurch Scientific Universal Prime/Purge Valves are easy to operate. Simply install a valve along the flow path with the included fittings and attach a luer-tipped syringe. Then, withdraw the plunger and watch as solvent and residual bubbles are removed from the solvent line. The valves automatically close when the syringe is removed. The low pressure version of the valve is designed to be used with /8 OD tubing, while the high pressure version accommodates /6 OD tubing. Optional mounting is made easy by the handy holes in the body of each unit. Air in the let Solvent Line stall the Low Pressure Universal Prime/Purge Valve along the inlet solvent path near the pump to remove bubbles from the inlet solvent line. The valve can also be used to rapidly wet your solvent inlet filter. When a new filter is installed, it often contains a substantial amount of air within its pores. At standard flow rates, it may require several minutes before the inlet fluid pathway is completely free of gas. Using this valve you are able to rapidly draw solvent through the inlet filter, dislodging the gas and minimizing downtime. Air in the Pumphead Air within the pumphead can cause flow instability and noisy pump operation. Place the High Pressure Prime/Purge Valve between the pump and the sample injector, where it can be used to remove bubbles that have become lodged within your pump. This valve is rated for a maximum pressure of 5,000 psi (5 bar). Luer Port Check Valve Assembly.8.9 V- Low Pressure Universal Prime/Purge Valve Mounting holes are.75 apart 06 The wetted materials for our Waters-compatible and Universal Prime/Purge Valves are ruby, sapphire, PEEK, Teflon and stainless steel. For another luer check valve option, see the Quick-Stop Luer line Check Valve on page. Order Tel: / Prime/Purge Valves V-0 Prime/Purge Valve for Waters Pumps cludes () V-0-06 Teflon seal V-0-06 Replacement Teflon Seal (for V-0) V- Low Pressure Universal Prime/Purge Valve cludes () P-00N Tefzel Ferrules & () P-5 PEEK Nuts, for /8 OD tubing V- High Pressure Universal Prime/Purge Valve cludes () F-0 Fittings for /6 OD tubing B-0 0cc Disposable Luer-Tipped Syringe