E-Fiber Modular electrospinning platform

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Millicent Barnett
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ADVANCED VERSION E-fiber electrospinning advanced version is optimal for research centers, companies and universities whose needs are to produce nanomaterials intended both for commercial and

1 ADVANCED VERSION E-fiber electrospinning advanced version is optimal for research centers, companies and universities whose needs are to produce nanomaterials intended both for commercial and research purposes. E-fiber is a fully-customisable electrospinning platform consisting of injection stages and application-specific collectors (static or movable), for the laboratory-scale manufacturing of polymeric-nanofibrous matrices. This device creates a powerful and highly versatile technique for the creation of various fibrous architectures with controlled fibre diameter and orientation. Its technology minimises influence on the electrospinning process. E-fiber offers various technological solutions to accurately control each process guaranteeing batch-to-batch reproducibility and precise control of fibre parameters such as diameter, orientation and texture. The equipment is user-friendly and safe thanks to the automatic safety devices that protect the operator.

The Advanced Version includes all the necessary instrumentation for a complete and ready to use setup, to rapidly begin your electrospinning sessions.

2 The Advanced Version includes all the necessary instrumentation for a complete and ready to use setup, to rapidly begin your electrospinning sessions. E-Fiber Desktop advanced version, includes: desktop fume-hood, high voltage power supply 0-40 kvolt, control system with LCD console, 2-channel syringe pump* with external control, insulating base with distance adjusting, double spinneret support, collector support, coaxial spinneret and disposable kit. Disposable kit includes 2 stainless steel spinneret of 2 different diameters, 100 syringes, tygon/ptfe tubing (7.5m), polypropylene male and female luer connectors (15+15). E-Fiber can be equipped with a variety of add-on modules and accessories to extend and best fit user requirements and applications, such as complex movimentation, coaxial needles, multispinneret systems, additional sensors, custom-shaped targets etc. Double high-voltage power supply options for specific requirements or applications : -30kvolt / + 30kVolt * System is installed in a TUV certified fume-hood with active carbon filter (customizable for specific solvent and chemical agents). System is also available in Standalone Version. 1

3 TECHNICAL DATA High-voltage power supply (CE and UL mark) Voltage * Current * Power * Arc and Short-circuit protection Safety Interlock Voltage Stability Single supply 0-40 kv Dual supply +/- 30 kv Single supply 1.5mA Dual supply 4mA Single supply 60 W Dual supply 120W Yes Yes 0,02% per 8 h * Fully customizable features Syringe pump Programmable Channels 2 Syringe up to 60 ml Flow rates from µl/hr (1 ml syringe) to 7515 ml/hr (60 ml syringe) Accuracy +/ % Channels 6 Syringe up to 60 ml Flow rates from µl/hr (1 ml syringe) to 1451 ml/hr (60 ml syringe) Accuracy +/ % Collector Shape * square Size * 120 [W] x 120 [D] x 2 [H] mm Material * stainless steel * Fully customizable features Spinneret Spinneret type* Spineret range size* Material* Single or coaxial spinneret 30G up to 10G stainless steel AISI304D * Fully customizable features 2

Interchangeable size rotating collector system Rotating collector used to electrospin cylindrical or big planar structures with oriented and non-oriented fibers (depending on rotation speed).

4 ACCESSORIES E-Fiber can be upgraded with a variety of add-on modules and accessories to extend and best fit user requirements and applications. Custom collectors and spinnerets Collectors and spinnerets of various sizes, shapes, materials and surface finishes. Fully customizable and made according to customer specifications. Interchangeable size rotating collector system Rotating collector used to electrospin cylindrical or big planar structures with oriented and non-oriented fibers (depending on rotation speed). This version can house cylindrical collectors (mandrels) with different diameters and lengths and, because it is highly flexible and versatile, it is ideal for research applications. Supplied with 5 collectors of different diameters. Easy keypad and LCD based user interface. Entirely made in plastic, in order to guarantee no interferences with electrical field and electrospinning process. Electronic feedback for a precise control over speed rotation, in order to guarantee highly reproducible batch-to-batch conditions. 3

Custom rotating collectors Variable mandrels made according to customer specifications regarding length, diameter, material and surface

Spinneret linear motion Spinneret linear motion device to achieve greater static or rotating surface coverage.

Ideal for scaling-up application and small medium scale of manufacturing requirements.

Entirely made in plastic, in order to guarantee no interferences with electrical field and electrospinning process.

5 Custom rotating collectors Variable mandrels made according to customer specifications regarding length, diameter, material and surface finish. Compatible with the interchangeable size rotating collector system. Spinneret linear motion Spinneret linear motion device to achieve greater static or rotating surface coverage. It is used to electrospin large planar formats (for example, A4 size or bigger) or long cylinders. Ideal for scaling-up application and small medium scale of manufacturing requirements. Fully compatible with our E-Fiber platform and our rotating collector. Easy keypad and LCD based user interface. Entirely made in plastic, in order to guarantee no interferences with electrical field and electrospinning process. Electronic feedback for a precise control over speed rotation, in order to guarantee highly reproducible batch-to-batch conditions. Multispinneret support Insulating support to house up to a maximum of 12 spinnerets, used for large planar formats or continuous strip electrospinning machines. Compatible with multi-channel syringe pump E-Fiber version. 4

Coaxial spinneret needle Coaxial spinneret needle made of two coaxial needles, used to simultaneously electrospin up to two different polymers.

Detachable options for easy cleaning operations. Minimum dead volume.

Generally used to create fibers with core and shell made of different materials. Ideal for research purposes.

6 Coaxial spinneret needle Coaxial spinneret needle made of two coaxial needles, used to simultaneously electrospin up to two different polymers. This is generally used to create fibers whose core and shell are made of different materials. Ideal for research purposes. Detachable options for easy cleaning operations. Minimum dead volume. Triaxial spinneret needle Triaxial spinneret needle, made of three coaxial needles, used to simultaneously electrospin up to three different polymers. Generally used to create fibers with core and shell made of different materials. Ideal for research purposes. Detachable options for easy cleaning operations. Minimum dead volume. Multichannel Syringe pump Replaces the standard supplied syringe pump and is used to electrospin high quantity of solution through multiple syringes, for big target collectors, or to use co- or tri-axial spinneret. Available with two, four, eight channels. Compatible with multispinneret support. 5

High voltage power supply with controller HIgh voltage power supply 0-40 kvolt, other voltage on

Double high voltage power supply options for needleless technology upgrade or specific applications:

100kVolt electric field). CE and UL certified.

7 High voltage power supply with controller HIgh voltage power supply 0-40 kvolt, other voltage on request. Double high voltage power supply options for needleless technology upgrade or specific applications: -30kvolt / +30kVolt, -40kvolt / +40kVolt, -50kvolt / +50kVolt, (resulting in a 60kVolt, 80kVolt or 100kVolt electric field). CE and UL certified. Benchtop fume-hood TUV certified fume-hood with active carbon filter (customizable for specific solvent and chemical agents), in Desktop or standalone version. E-fiber can be completely integrated in the fume-hood. Available in different dimensions and versions. 6

Pump remote control Control pedal or push button for the remote activation of the syringe pump's ON OFF function, useful outside hoods with lowered glass panel.

8 Pump remote control Control pedal or push button for the remote activation of the syringe pump's ON OFF function, useful outside hoods with lowered glass panel. Other accessories, moving devices and systems are custom designed and manufactured according to the application or customer specifications. All the technical specifications of each single accessory can be provided upon request. E-Fiber - Order information E-fiber Advanced Version Order Code E-Fiber Advanced Desktop Version (0-40KVolt) E103-1 E-Fiber Advanced Desktop Version (+/- 30KVolt) E103-2 E-Fiber Advanced Standalone Version (0-40KVolt) E104-1 E-Fiber Advanced Standalone Version (+/- 30KVolt) E104-2 E-fiber accessories Order Code Custom collectors E201 Custom spinnerets E202/203 Interchangeable size rotating collector E211 Customized mandrels E212/215 Spinneret linear movement E216 Multispinneret support E217 Coaxial spinneret E218 Triaxial spinneret E219 Multichannel syringe pump E205-1/6 High voltage power supply with controller E221/222 Spare parts/replacement Disposable pack Order Code E204 SKE Research Equipment C/O Leonardino Srl via Don Giovanni Minzoni, Milano Italy tel/fax: website: For information: info@ske.it Sales request: sales@ske.it 7

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