ELECTROSPINNING FROM THE LABORATORY. Produced by the Biomedical Division of Linari Engineering S.r.l..

Transcription

1 ELECTROSPINNING FROM THE LABORATORY Produced by the Biomedical Division of Linari Engineering S.r.l.. Visit the website to discover the other products RTColl.2En Ed. 11/2010 1

2 Linari Engineering proposes a complete kit to create a professional Electrospinning system from the laboratory, starting from liquid solutions according to the classic scheme shown in the figure. Safe, easy installation Parameters that mainly affect the electrical drawing of polymers in liquid solution: Molecular weight and structure of the polymer (linear, ramified...); Physical properties of the solution (viscosity, electrical conductibility and surface tension); Environmental parameters (pressure, humidity, temperature); Applied potential difference; Distance between the end of the syringe needle and the collector; Configuration of the electrical field lines around the syringe; Syringe solution capacity; Collector speed (translation and/or rotation). Appliance components Control unit based on OMRON industrial electronics (PLC & Motor drivers); Software with graphic interface and deposition programming based on industrial SCADA; Linear sliding guide with stroke equal to 250 mm and maximum speed of 1 m/s and resolution of 0.1 mm; Rotating axis in two directions up to 4500 rpm. Rotating diameters between 1 and 70 mm. All the electrical equipment is powered by mains voltage 230 or 110 V. RT Collector originates pre-set up for connection to the HV generators supplied by Linari Engineering in our Starter kit, or to existing devices. The system has been designed to provide maximum protection against the high voltages that may be used in the work area of the RT Collector with the use of insulating materials and specific construction techniques. To guarantee that access to the equipment takes place in absolute safety, a safety switch must be attached to the access door/window to the work area, which also intervenes on the high voltage generator, turning it off. A red light will notify the operator of the function condition of the experiment. Customisation and service All our kits are packaged and tested to comply with the specific customer requirements. The following are available on request: o Increased stroke (up to 1 m); o Rotation speed up to rpm; o Collectors in geometries and materials on request; o Remote control of the high voltage generators towards existing analogue or digital type systems; o Systems controlling room air temperature and solution; o o Inverter systems to partition hood suction; Development of mechanical and electrical interfaces for experiments or existing plants. Technical assistance and installation service are managed directly by Linari Engineering staff, with no agents or intermediaries worldwide. RTColl.2En Ed. 11/2010 2

3 Applications Given the facility and flexibility of use and integration of the machine within the articulated experiments, the RT Collector can be used in all applications today involving the use of electrospinning. The system, including the HV generators, is entirely controlled by the specific software that provides a monitoring of operative conditions and the programming of complex deposition cycles, which can last several hours, through intuitive wizards designed for the production of tubular and flat structures. Fabric engineering and regenerative medicine; Study of nano spun fiber polymer materials; Scaffold production; Spun fiber production; Production of filters and membranes; Production of innovative nano materials; Fuel cell; Coaxial electrospinning. To implement the deposition parameters, all system variables can also be 'manually' managed by simple commands that are safe, thereby guaranteeing a successful outcome of tests and the safety of people and machinery. PVA fibers aligned at 3000 rpm on mandrel Ø4 mm Method of use The system can be used both as a simple sliding system by removing the end arch, illustrated below in the figure, and fixing a plate in its place by means of the specific calipers (This is the only available solution for BASE configuration). Thanks to a wide customization of each feature the RT Collector is the ideal solution for every R&D activity where scientists want to control every boundary condition without geometrical limit like pump orientation, volume accessibility and special shape of electric field with auxiliary metallic electrodes. RTColl.2En Ed. 11/2010 3

4 Use with two HV generators RT Collector is able to manage until two different HV generators from its hardware and software interface. While the first one is applied to the needle, the second one (usually with opposite polarity) can be connected directly to rotary/translating collector. This configuration is available thanks to high dielectric strength of materials used to support the collector itself to cut leakage current to motors and control system. With the second generator the user can obtain two different results: Increase electric field around tip without risk of ground discharge with a reduction of primary voltage level, thanks to the sum of secondary filed. Active drain of charges from nanofiber collected thanks to voltage level lowers than 0V of the ground. It increases diameter stability of nanofibers during long deposition session. generator. This configuration reduces the self-shield effect of the target and maintains a more uniform diameter during long electrospinning session and it reduces dependencies from environmental conditions like temperature and humidity. Dielectric collector is suitable for special electrostatic configurations where ground (or reverse polarity) is applied to blades, plates or tip placed rear the collector itself to obtain special orientation of electric field lines. Dielectric material produce only a small deviation of electric field generated form needle and plaques to maintain the designed configuration. Collectors: rod, drum, disks and other shapes On RT Collectors grips it s possible to mount different collectors made in several materials, both conductive and dielectric. Our in stock collectors are made in Teflon, fiber glass, stainless steel, aluminum and chrome plated brass. Every piece is made with special ends to allow the mounting over the standard grips. Thanks to good quality machining and low inertia these collectors can run at high speed without excessive noise and vibrations. We Electric field throw dielectric and between conductors are available to develop and manufacture custom design for your collectors with special materials and geometries like polygonal to place scaffold or samples to be covered with nanofibers deposition for electronic sensors and biosensors. With metallic collector it s possible to drain the electric charge of nanofibers to ground or to reverse polarity HV RTColl.2En Ed. 11/2010 4

5 Technical data Sliding movement BASE Version Unit Value Notes Motor Type Brushless AC Power supply Volts 110/230 V AC Feed speed mm/s Transmission type Toothed belt Direct socket on engine Sliding guide Steel wheels Tempered steel guides Mechanical run mm Useful run mm constant speed Position accuracy mm +/- 0.1 Total mobile mass Kg 2.0 at maximum speed Rotation movement - Optional Power supply Volts 110/230 V AC Enabling Type Brushless AC Rotation speed Rpm Optional up to rpm Speed accuracy Rpm +/- 1 Rotating axis support Ball bearings Life lubricated SUPPORT ARCH AND COLLECTION SYSTEMS Unit Value Notes Net sample length mm standard Rotating mandrel collection system Self-centring or Customised on request Dremel callipers Diameter that can be clutched mm Customised on request Rotating diameter in the arch mm Customised on request Electrical connection on mobile arch YES M3 x 6 Dismountable arch YES Interchangeable grip mandrels YES Dremel MOTION CONTROL BOARD Unit Value Notes Controller Industrial PLC Omron Power supply Volts 110/230 V AC IEC connector Maximum power consumption W 700 Without HV generators Communication interface RS485 RS232, USB or Ethernet as option 0..10V output for HV generators control No. 2 Opto-isolated as option 0..10V inputs for monitoring No. 4 Generators feedback for V and I, as option PC-controlled digital inputs No Option PC-controlled digital outputs No Option Light warning system YES Software for PC with Windows 7/Vista/XP YES 1 license included Languages available for software No. 3 Italian, English, Spanish PC - controller connection cable m 5 Serial or USB or Ethernet Width cm 50 Depth cm 25 Height cm 70 Weight Kg 15 Full optional RTColl.2En Ed. 11/2010 5

6 AVAILABLE DEPOSITION PROGRAMMES Unit Value Notes Movement management strategies No. 3 Voltage management strategies No. 3 Optional Combination of movement & voltage strategies Any 9 combinations Dimensions of RT Collector with rotating mandrel and 150 mm arc RTColl.2En Ed. 11/2010 6

7 Linari Biomedical Division PRODUCTION Electrospinning equipment o High Voltage generators o Rotary-sliding mandrel system o Shaped collectors and screens for directing electrical field o Coaxial and multiple needles o Fitting out of complete systems and hoods for experiments on request Bioreactors for cell culture o Perfusion with innovative flexible flow system o Rotating walls with single and dual culture chamber o Digital peristaltic pumps adjustable up to 1/100,000 of maximum capacity Data acquisition system and sensors o Low cost data acquisition systems on PC o Miniature sensors RTColl.2En Ed. 11/2010 7

8 Contact us LINARI ENGINEERING S.r.l. Registered offices: via dei Colatori, Valpiana (Grosseto) - Italy Manufacturing site: via Umberto Forti 24/ Pisa - Italy VAT no.: IT Tel. (+39) Fax (+39) Skype: linari_engineering e mail: info@linarisrl.com web: RTColl.2En Ed. 11/2010 8