SMC - The Pharmaceutical Industry in the Spotlight. SMC a one-shop-stop for the pharmaceutical industry

Transcription

1 SMC - The Pharmaceutical Industry in the Spotlight SMC a one-shop-stop for the pharmaceutical industry

2 SMC - working in the pharmaceutical industry: As the world s leading experts in pneumatics, with more than 360 sales offices in 78 countries, we have developed a truly impressive and extensive portfolio of highly sophisticated automation related products. Today, our standard product range exceeds items, with over variant forms, with many specifi ed and used in a growing number of pharmaceutical applications throughout the world. With a focus on component quality and long life-cycle performance SMC products can help increase your productivity, guarantee the highest levels of manufacturing quality and also reduce both waste and energy consumption. By selecting an SMC product for your next pharmaceutical application outstanding operational performance is a given and peace of mind is ensured. Understanding the needs of the pharmaceutical industry: The pharmaceutical industry is one of the most highly regulated industries in the world. As leaders in our fi eld, our highly trained pharmaceutical industry experts recognise and fully understand the strict standards set by organisations like the FDA (USA s Food and Drug Administration) and the GMP (Good Manufacturing Practise) guidelines from the International Society for Pharmaceutical Engineering. With more than1.360 dedicated R&D engineers located at our Technical Centres around the world, we are an organisation committed to continuous product development and product improvement. And for this reason, the introduction of the PAT initiative (process analytical technology) from the FDA, which promotes the tangible benefi ts of using new technology in pharmaceutical manufacturing processes to increased yields, reduce waste and save money, is path that we also follow and fully applaud. Through our industry knowledge, we recognise the pharmaceutical industry s unique mix of both process and discreet manufacturing processes, including the growing use of automation in R&D laboratories seen during the last decade. From process automation applications used in primary manufacturing, through to secondary manufacturing applications, including formulation and fi nal packaging, and fi nally the use of automation in laboratories, SMC can provide you with accurate, high quality, cutting edge product solutions to meet all your pharmaceutical needs. 2

3 A selection of SMC products developed and used in the pharmaceutical industry: Flow and pressure switches Series PFM 2-Colour Display Flow Switch For air, N 2, Ar and CO 2 A compact digital flow switch that uses MEMS sensor for detecting the flow Improved visibility with two colour display indication Two piping directions are possible Integrated flow adjustment valve Multiple mounting combinations Flow rate range: 10, 25, 50, 100 l/min Series PFMV Flow Sensor and Voltage Monitor Suction check of very small workpieces PFMV5: Flow sensor PFMV3: Voltage monitor for PFMV5 Reduced piping space Response speed: 5 ms or less Applicable fluid: Dry air, N 2 and Ar Flow rate range: 0.5, 1, 3 l/min Series PF2D Digital Flow Switch for Deionised Water & Chemicals Dust generation of 3 particles/cc or less (average number) Karman vortex eliminates moving parts and allows low dust generation Swept flow characteristics Tapered side seal minimises dead volume to reduce accumulation of liquid pool Body and Sensor: New PFA Tube: Super PFA Three type of flow range: 0.4 ~ 4 l/min, 1.8 ~ 20 l/min, 4.0 ~ 40 l/min Series PF3W Digital Flow Switch for Water Integrated temperature sensor Space saving, reduced piping space 3 colour/2 screen integrated or remote display Rotatable display: easy operation, improved visibility Analogue output: 1-5 V or 4-20 ma Switch output: PNP/NPN Integrated flow adjustment valve Accumulated pulse output (NPN/PNP) Accumulated flow output (NPN/PNP) External input (NPN/PNP) Four type of flow range: 0.5 ~ 4 l/min, 2 ~ 16 l/min, 5 ~ 40 l/min, 10 ~ 100 l/min 3

4 Sensors Series PSE550 Low Differential Pressure Sensor For air or dry gases Measures ± 2 kpa (0.3 Psi) 1-5 V or 4-20 ma analogue output options Direct connection of 4 mm ID tubing Typical applications, filter back pressure monitoring or fan output checking Mounting bracket available Integrated indicator light Series PSE560 Pressure Sensor for General Fluids Pressure sensor for general purpose fluids (controller: PSE300) Wetted material: SUS316L Pressure range: positive pressure [0 to 500] kpa and [0 to 1] MPa, vacuum [0 to101] kpa, compound pressure [ 100 to 100] kpa Series PSE200 Multi-channel Controller Sensor controller unit for 4 sensor inputs Automatic sensor recognition Auto shift function Series ISE30A Adjustable Positive Pressure Switch with Display For use with air and nitrogen Enclosure IP40 2 colour (green/red), large, easy-to-read display Easy operation: 3-step setting and copy function Analogue output: 4-20 ma or 1-5 V Switch output: 2 PNP/NPN or 1 PNP/NPN Series ISE40A Adjustable Positive Pressure Switch with Display For use with air and nitrogen Enclosure IP65 2 colour (green/red) display Easy operation: 3 step setting and copy function Outputs: analogue (1-5 V, 4~20 ma), 1/2 x PNP/NPN 4 Series ISE80/ZSE80 2-Colour Display Digital Pressure Switch 4 Rated pressure range: 0.0 to kpa; to kpa; to MPa; to 2.00 MPa Stainless diaphragm (Oil-free Single-layer diaphragm) Sensor parts: Stainless steel 630 Fitting parts: Stainless steel 304 For use with water, hydraulic fluid, silicon oil, lubricant, fluorocarbon, Ar, ammonia, CO 2, air-containing drainage and N 2 Outputs: analogue (1-5 V, 4~20 ma), 1/2 x PNP/NPN

5 Stainless steel products Series SRH Contamination Controlled Stainless Steel 316/316L Regulator Outstanding corrosion resistance Oil-free Low particulate contamination Two types of diaphragm materials: PTFE, Fluororubber Designed to minimize residual fluid Pulsation suppressing design Consistent clean room production Wetted parts (metal): Stainless steel 316 (Body is SUS316L) On demand: all wetted parts in 316L / Tri-Clamp connections Series KQG2 Stainless Steel 316 One-touch Fittings Material: Metal parts: Stainless steel 316 Seal parts: Special FKM Can be used with air, water and steam Operating fluid temperature: 5 to 150 C Grease-free Applicable tubing material: FEP, PFA, nylon, softnylon, polyurethane, polyolefin Series KFG2 Stainless Steel 316 Insert Fittings Material: Stainless Steel 316 Operating fluid temperature 65 to 260 C Can be used with steam Grease-free Applicable tubing material: FEP, PFA, modified PTFE nylon, softnylon, polyolefin polyurethane, soft polyurethane, hard polyurethane, soft polyolefin, antistatic softnylon, antistatic polyurethane Series ASG Stainless Steel 316 Controller (Elbow type) Stainless steel 316 and special FKM construction to improve the resistance to corrosion Elbow design to allow the rotation of the tubing connection ports and suit installation to air cylinders Meter-in and meter-out type control One-touch fittings and 5 body sizes 5

6 Series CJ5-S/CG5-S Stainless Steel Cylinder SUS304 - stainless steel Special scrapers provide optimum piston rod sealing Seals either NBR or FKM FDA approved grease suitable for food processing applications CG5 can be disassembled, therefore maintenance-friendly HYB Round type HYC ISO standard type HYQ Compact type HYG Guide rod type Series HY Hygienic Design Cylinder Four body types, compact, ISO/VDMA, guide rounded profile Water resistant to resist washdowns No external grooves or crevices to trap dirt External switch rail and IP67 autoswitches available Mounting dimensions meet ISO/VDMA standards NBR or FKM external seals with food grade grease option Hygienic smooth design for easy cleaning Clearance under switch rail to avoid trapping debris Mounting brackets are available, plus cover plates for HYQ Bore sizes from 20 mm to 100 mm Air filtration 6 Series AF Filter In stacking manifold or as single device Filtration degree 5 μm Optional manual or automatic drain 3 bowl materials for different types of use (polycarbonate, nylon, metal) Filter cartridge element can be changed quickly. Temperature range -5 to 60 C Vertical mounting position Series AFM Mist Separator In stacking manifold or as single device Filtration degree 0.3 μm Residual oil concentration at the outlet max. 1 mg/m³ Filter cartridge element can be changed quickly Temperature range -5 to 60 C Vertical mounting position Series AFD Micro-Mist Separator Filtration 0.01 μm Residual oil concentration at the outlet max. 0.1 mg/m³ Filter cartridge element can be changed quickly Temperature range -5 to 60 C Vertical mounting position

7 Series AMF Odour Removal Active carbon filter for filtering odours Filtration degree 0.01 μm Residual oil concentration at the outlet max mg/m³ 13 layers of active carbon ensure optimum effectiveness Operating pressure range 0.05 to 1.0 MPa Temperature range 5 to 60 C Modular connection (AMF150C to 550C) Series SFA Clean Gas Filter Cartridge Type / Disc Style Precision filtration for general gases: compressed air, nitrogen, etc PTFE membrane element is made into a cartridge (polyester holder and fluorine rubber/fkm gasket) Filtration 0.01 μm Elements are replaceable Series SFB Clean Gas Filter Cartridge Type / Straight Style SFB100/200 Disposable Type / Straight Style SFB300 Precision filtration for general gases: compressed air, nitrogen, etc Element: PTFE membrane (SFB100/300), stainless steel 316 sintered metal (SFB200) Nominal filtration: 0.01 μm (SFB100/300), 120 μm (SFB200) Bracket is included as standard Series SFC Clean Gas Filter Disposable Type / Multiple Disc Style Precision filtration for general gases: compressed air, nitrogen PTFE membrane with high reliability Filtration 0.01 μm Series SFD Clean Gas Filter Disposable Type / Straight Style SFD100 Cartridge Type / Straight Style SFD200/SFD101/SFD102 Filtration in a clean environment for air or nitrogen Hollow fibre element Case material: resin (SFD100/200), aluminium (SFD101), stainless steel (SFD102) Filtration 0.01 μm 7

8 Series LLB Clean Air Module Modular clean equipment (reduction of piping labour/space-saving). Easily available clean air Nominal filtration rating: 0.01 μm Wetted parts: Grease-free, Silicon-free Assembled in a clean room, shipped and packed in duplicate packaging 24 combinations available Temperature control Series HRS Circulating Fluid Temperature Controller Thermo-Chiller Compact Type Compact and lightweight Power supply options for global applications Energy saving (with heating function) Easy maintenance: tool-less maintenance of filter Self diagnosis function and check display Convenient functions: - Timer operation function - Low tank level detection function - Power failure auto-restart function - Anti-freezing operation function Communication function: RS232C, RS485 and contact I/Os as standard Series HEB Thermostatic Bath High-precision temperature-regulation thermostatic chamber that employs Peltier elements Compact and low vibration Unique agitation method keeps up-down temperature distribution to a minimum 8 Series HEC Thermo-con For applications requiring high-precision temperature control High-precision, refrigerant-free temperature control equipment employing Peltier elements Simple structure and high reliability Can easily be built into equipments with compact and low-vibration design Compatible with wide range of power supply voltages Conforms to UL standard, CE marking

9 Tubing Series TD Soft Fluoropolymer Tubing Improved flexibility by approximately 20% Material: Denatured PTFE. Operating temperature max. 260 C Conforms to FDA Ten different diameter sizes - in both imperial and metric Series TL High Purity Fluoropolymer Tubing Outstanding corrosion resistance Compatable with max fluid temperature up to 260 C High purity and low particulate generation Erfüllt die Vorgaben der FDA Material PFA 451HP-J Fourteen different diameter sizes - in both imperial and metric Series TH FEP (Fluoropolymer) Tubing Heat resistance to 200 C 4 Colour variations General pneumatic piping applications (Food, Semiconductor, Medical care and Automotive) Erfüllt die Vorgaben der FDA Material FEP 130-J Nineteen different diameter sizes - in both imperial and metric Grippers Series MHZJ2 Parallel Air Gripper with Dust Cover ø6, 10, 16, 20, 25 Applicables in alimentary industry, assembly lines, machine tool, etc Dust tight, drip proof construction Dust cover material selectable Series MHK2 Wedge Cam Operation Slide Guide Air Gripper ø12, 16, 20, 25 Gripper fingers have robust slide bearing Elastic guide cover in 3 different materials as protection against soiling by dust, chips, liquids, etc 2 Series: MHK2 standard, MHKL2 larger finger opening stroke 9

10 High Purity Teflon Series LVA LVH LVC Series LV HIgh Purity Chemical Valve Piston damper to minimise particle generation PTFE diaphragm to prevent micro-bubble generation New PFA body provides outstanding corrosion resistance Threaded Ports Series LVA Wetted parts material: PFA, Stainless steel or PPS (body), NBR, EPR or PTFE (diaphragm) Integral Fittings Series LVC High temperature chemical fluid handling possible (100ºC) Wetted parts material: PFA (body), PTFE (diaphragm) Manual Operation Series LVH Locking and non-locking types available Integral fitting type / Threaded type LVD Series LVD 2 Port Air Operated Compact valve: dimension across inlet/outlet ports reduced by up to 25%. Minimal internal dead volume. Integral fitting construction: Hyper Fitting Series. Piston damper to minimise particle generation. Piping from 4 directions possible. Wide range of valve variations available. Wetted parts materials: PFA / PTFE. Process Pump Series Series PAF3000/5000 Automatically Operated Type Excellent corrosion resistance - Body material: new PFA; Diaphragm, seal material: PTFE. Automatically operated (discharge flow rate max. 45 l/min) / air operated (discharge flow rate max. 38 l/min) Series PB1313A Process Pump, Air Operated Single acting pump Compact, high capacity diaphragm pump to transfer and deliver a wide variety of fluids Discharge flow rate: max. 1 l/min Wetted part material: Polypropylene SUS316 10

11 Valves Series Series LVM Gas and Chemical Liquid Valve Direct operated diaphragm type valve Valve chamber volume up to 20 μl or less Minimal internal dead volume Compactness (width: 13 mm) and lightweight (30 g or less) Energy saving: low power consumption (1-2.5 W) Service life of 10 million cycles. (Based on SMC test conditions) Body ported and base mounted valve options Wetted parts material: PEEK or PFA. Base mounted valve only (plate) and EPDM, FKM, or Kalrez (diaphragm) Other voltages available (DC) Series SY3000/5000 Solenoid Valves 5 Port, Manifold Type Highly flexible Long life circle Inside cabinet mounting is possible with bottom type Energy saving: 0.1 W with power saving circuit 0.35 W standard Space saving: 10 mm width Top, bottom, side porter available Wiring, piping and operation are integrated in one side Direction, size and type of the piping can be changed Ionizer Series Series IZS31 Ionizer Three ion emission modes: sensing DC, pulsed DC or DC modes Maximum 60 Hz ion generation frequency Two types of compact sensors are available: Autobalance sensor and Feedback sensor Aerodynamic cross section Air purge function for even faster static electricity elimination Three types of needle material: Tungsten (standard), silicon and stainless steel Replaceable electrode needles Dirt detection 11

12 Electric drivers Series Series LE Easy Setting Electric Actuators Our expanding range of high performance electric actuators, combine the best features of pneumatic cylinders with the accuracy and strengths of electric drives. Easy to programme thanks to their in-built easy setting software - these actuators can be installed and fully operational within minutes when used in conjunction with our new LECP1 Controller. Available in comprehensive range of model options these electric actuators, which can accommodate up to 64 speed and positioning settings, really do offer outstanding operational performance. Series LE options include: linear actuator model types electric grippers types - including our LEHZJ models, which incorporate special protective covers for dust protection rotary actuator model types LECP1 easy to use controller Series LAT3 NEW PRODUCT Card Motor Similar in size to a credit card, this extremely compact linear actuator offers outstanding speed and accuracy. Gas handling components AP Tech a specialist business within the SMC Corporation: AP Tech, also known as Advanced Pressure Technology, manufactures a wide array of gas handling components used predominately in the Semiconductor, Life Science and Pharmaceutical markets. Pressure regulators, valves, check valves and a variety of flow devices are available for applications ranging from the source cylinder cabinet, bulk delivery systems through point of use including VMB distribution boxes and process tool gas trays. Products can be tailored for specific needs with custom fittings, dimensions, porting or testing with an option of multi-port, mono-block and surface mount configurations. For more information on the AP Tech range contact your nearest SMC office today. 12

13 Plastic Manifold & Valve Custom Engineered Plastic Manifold & Valve Technology To help: Reduce space Reduce weight Reduce installation time and error Reduce cost of ownership SMC offers you the benefit of single source supply of plastic manifolds and valves. With a wide selection of valves to meet our customers needs Using our highly experienced in-house design resource Cleanroom Products SMC Pneumatic Clean Series By recognising the needs of specialist industry sectors, we have developed one of the largest portfolios of clean room manufactured products around. With our state-of-the-art manufacturing facilities and highly trained clean room technicians, we guaranteed that any product selected from our SMC Clean Series will meet the right standards and levels for all your applications needs. Our Clean Series Catalogue (CAT.E02-23A) includes: Air Cylinders Rotary Actuators Air Grippers Directional Control Valves Flow Control Equipment Filters and Pressure Control Equipment Fittings and Tubing Air Preparation Equipment Pressure Switches Clean Gas Filters For information on our extensive range of clean room manufactured products please contact your nearest SMC office. 13

14 Applications Series HRS Series HRS is a new range of thermo chiller units that are ideal for use in blister packaging machines. When used in these applications, the HRS thermo chiller can heat the blister tooling at beginning of the process and then cool the tooling during production. Advantages of using an HRS in your blister packing machine: - Only one device needed for both heating and cooling - Overall weight reduction - Less installation space required - Cost savings Atomizing device Temperature control of sample and device Concentrating equipment Temperature control of concentration fluid Reagent cooling equipment Temperature control of reagent Series SRH As a part of our gas regulator range Series SRH, we have developed a clean gas option Series SRH4011, with all wetted parts made of stainless steel 316L. This regulator is the perfect solution for applications that require clean air flow such as drying vials. Available with optional Tri Clamp connections, subject to order, this regulator has been designed to meet the needs of a growing number of pharmaceutical applications. Clean rooms 14

15 Series AXT115 Quick-acting valve for high speed sorting applications Given the increasing demand from the industry we have developed a range of quick-acting valves with a switching time of ON/OFF 2.5 ms respectively. They are ideal for tablet presses and sorting applications, both before and after pressing. These valves are available as a flange version and can be used for numerous applications. CAD Model AXT115 SMC a one-shop-stop for the pharmaceutical industry Three of the most important demands from the pharmaceutical industry are: reliability, flexibility and speed. SMC has the resources and capability to meet these demands. With a comprehensive range of products and innovative solutions we can support our pharmaceutical customers throughout the complete process production, packaging and analysis. SMC offers products with FDA certified materials and has: - the widest range of pneumatic products on the market - an expanding range of new easy to programme electric drives - an extensive portfolio of process valves - a large selection of instrumentation components including pressure and flow sensors - Clean room and high purity products - a growing range of high performance thermo chiller and thermo controllers - an extensive range of products developed for analytical devices and laboratories see our Life Science catalogue for more details 15

16 EMC-PHARMA01 -UK SMC CORPORATION (Europe) Austria +43 (0) Belgium +32 (0) Bulgaria +359 (0) Croatia +385 (0) Czech Republic Denmark Estonia Finland France +33 (0) Germany +49 (0) Greece Hungary Ireland +353 (0) Italy Latvia Lithuania info@smclt.lt Netherlands +31 (0) info@smcpneumatics.nl Norway post@smc-norge.no Poland +48 (0) office@smc.pl Portugal postpt@smc.smces.es Romania smcromania@smcromania.ro Russia info@smc-pneumatik.ru Slovakia +421 (0) office@smc.sk Slovenia +386 (0) office@smc.si Spain post@smc.smces.es Sweden +46 (0) post@smc.nu Switzerland +41 (0) info@smc.ch Turkey info@smcpnomatik.com.tr UK +44 (0) sales@smcpneumatics.co.uk SMC CORPORATION Akihabara UDX 15F, , Sotokanda, Chiyoda-ku, Tokyo , JAPAN Phone: FAX: st printing QU printing QU 05 Printed in Spain Specifications are subject to change without prior notice and any obligation on the part of the manufacturer.