Reagents on Roche/Hitachi Systems
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1 ~mg/dl ~mg/dl ~mg/dl ~µmol/l ~µmol/l ~µmol/l Turbidity ACP Acid Phosphatase X ACP-NPP Non-protstatic Acid Phosphatase X Acetaminophen 5µg/mL X X X X <1 <1 <10 <17 <17 < Acetaminophen Acetaminophen 30µg/mL X X X X no Acetaminophen 50µg/mL X X X X no Albumin Albumin BCP X X X Albumin plus Albumin BCG X X X Albumin Tina-quant Albumin (turbidimetric) X X X Amikacin ONLINE TDM Amikacin X *5 X *5 X * ALP IFCC liquid Alkaline phosphatase IFCC X X ALP opt Alkaline phosphatase opt X X ALT/GPT IFCC Alanine Aminotransferase IFCC X X X Ammonia Ammonia X n/a under evaluation - 1 -
2 AMYL liquid α Amylase X X X P-AMYL liquid α-amylase Pancreatic X X X APOA1 Tina-quant Apolipoprotein A-1 X X X APOB Tina-quant Apolipoprotein B X X X ASLO Tina-quant Antistreptolysin O X X X AST/GOT IFCC Aspartate Aminotransferase IFCC X X X ATIII Antithrombin III X a1-antitrypsin α1-antitrypsin X X X X b2-microglobulin β2-microglobulin X X X BICARB liquid Bicarbonate X X BIL-D Gen. 2 X X X n/a n/a n/a n/a 25 n/a n/a BILI-Total DPD Total (R/Hitachi 902 only) X X X n/a n/a n/a n/a 10 n/a n/a 6 75 BILI-Total DPD Total X X X n/a n/a n/a n/a 50 n/a n/a
3 TBILI liquid Total liquid X X X n/a n/a n/a n/a 1000 n/a n/a BILT3 Total Gen. 3 X X 4) X 8) n/a n/a n/a n/a 800 n/a n/a BILT3 Total Gen. 3 for Neonates X X 4) X 8) n/a n/a n/a n/a 1000 n/a n/a C3c Tina-quant Complement C3c X X X C4 Tina-quant Complement C4 X X X Ca Calcium X 6) X 4) Ca2 Calcium Gen. 2 X 6) X 4) CARB II CEDIA Carbamazepine X X X CDT Tina-quant Carbohydrate Deficient Transferrin X CHE 2 Cholinesterase 2nd generation X X CHE butyryl Cholinesterase X X X CHOL Cholesterol X X X CHOL Cholesterol HiCo X X X Cl Chloride Gen. 2 *5 X X 4) CK liquid Creatine Kinase X X X CK-MB liquid Creatine Kinase-MB X X X
4 Ceruloplasmin Tina-quant Crea Crea Ceruloplasmin X X X n/a Creatinine Jaffé rate blanked + compensated Creatinine Jaffé STAT compensated Intralipid not measured 2 X X X X X X Crea plus Creatinine enzymatic X X X CRPLX Tina-quant C-Reactive Protein (latex) X X X CRPHS Tina-quant C-Reactive Protein (latex) high sensitive X X X (2 mg/l) CRPHS Tina-quant C-Reactive Protein (latex) high sensitive X X X (4 mg/l) CRPHS Tina-quant C-Reactive Protein (latex) high sensitive X X X (5 mg/l) D-Bil Jendrassik Direct (Jendrassik) X X X n/a n/a n/a n/a 25 n/a n/a D-Dimer Tina-quant D-Dimer X X D-Dimer Tina-quant Gen. 2 D-Dimer Gen. 2 X 7) X 7) Digoxin II CEDIA Digoxin X X X Digoxin Tina-quant Digoxin X X X
5 Digitoxin CEDIA Digitoxin X X Digitoxin OnLine Digitoxin X X Ethyl Alcohol Ethanol (R/Hitachi 902) X X X X Ethyl Alcohol Ethanol (R/Hitachi 904, 911,912,917) X X X X Fe Iron X X FERRI Tina-quant Ferritin X X X X FRUCT Fructosamine X X X Gentamycin OnLine Gentamycin X X X GGT liqid γ-glutamyltransferase X X X GGT HiCo liquid γ-glutamyltransferase X X X GLDH Glutamate Dehydrogenase X X X GLU HK Glucose (Hexokinase) X X X X GLU GOD PAP Glucose (GOD PAP) X X X X
6 GPROT Tina-quant α1-acid Glycoprotein X X X HBDH Hydroxybutyrate Dehydrogenase X X X HDL-C plus 2nd gen. HDL-Cholesterol X X HDL-C plus 3rd gen. HDL-Cholesterol X X X HAPT Tina-quant Haptoglobin X X X n/a n/a n/a 1000 IGA Tina-quant Immunoglobulin A X X X IGA 2 Tina-quant Immunoglobulin A X X X IGAP 2 Tina-quant Immunoglobulin A - sensitive application X X X IGE Tina-quant Immunoglobulin E X X X X IGG Tina-quant Immunoglobulin G X X X IGG 2 Tina-quant Immunoglobulin G X X X IGGC Tina-quant Immunoglobulin G - sensitive application X n/a n/a - 6 -
7 IGM Tina-quant Immunoglobulin M X X X IGM 2 Tina-quant Immunoglobulin M X X X IGMP2 Tina-quant Immunoglobulin M - sensitive application X X X K Potassium Gen. 2 *5 X X 4) Kappa Tina-quant Kappa Light Chains X X X Lactate Lactate X Lambda Tina-quant Lambda Light Chains X X X LDH opt Lactate Dehydrogenase opt X X X LDH IFCC liquid Lactate Dehydrogenase IFCC X X LDL-C plus 2nd gen. LDL-Cholesterol X X Lidocaine ONLINE TDM Lidocaine X X X
8 LIP colourimetric Lipase X X LP(a) Tina-quant Lipoprotein (a) X X X n/a Intralipid not measured 2 LP(a) Tina-quant Gen. 2 Lipoprotein (a) Gen. 2 X X *9) X *9) MG Magnesium X X 4) Myoglobin Tina-quant Myoglobin X X X X Na Sodium Gen. 2 * 5 X X 4) NAPA CEDIA N-Acetyl Procainamide X X X Prealbumin Tina-quant Prealbumin X X X PHENO CEDIA Phenobarbital X X X PHENY OnLine Phenytoin X X X PHOS UV Phosphate (inorganic) X X X X PROC CEDIA Procainamide X X X QUIN OnLine Quinidine X X X RF II Tina-quant Rheumatoid Factors X X X
9 Salicylate 4mg/dL X Salicylate Salicylate 20mg/dL X Salicylate 30mg/dL X stfr Tina-quant Soluble Transferrin Receptor X X T Uptake CEDIA T Uptake X X X T4 CEDIA Total T4 X X X TP Total Protein X X X TG Triglycerides X X X n/a n/a THEO OnLine Theophylline X X X TOBR II CEDIA Tobramycin X X X Transferrin ver. 2 Tina-quant Transferrin X X X UA plus Uric Acid X X X UIBC Unsaturated Iron Binding Capacity X X
10 eagents on Roche/Hitachi Systems R Urea liquid Urea X X X Vancomycin ONLINE Vancomycin X X X VPA II CEDIA Valproic Acid X X X n/a = not applicable 1 Interferences were tested with the following substances added to samples: I Hemolysate up to 621 µmol/l (1000 mg/dl) hemoglobin up to 1026 µmol/l (60 mg/dl) Lipemia up to 20 g/l (2000 mg/dl). Lipemia has no units as it is a measure of turbidity. Only significant interferences (>10%) are listed in the package inserts Reference: Glick MR, Ryder KW, Jackson SA. Graphical Comparisons of Interferences in Clinical Chemistry Instrumentation. Clin Chem 1986;32: L index not measured with Intralipid, interference measured as Triglycerides (see package insert) Significant additions or changes (where present) are indicated by a change bar in the margin. 3 measured on Hitachi only Lithium 4 if Intereference for ISE-methods with Gentamycin reagent is necessary, please Contact Roche Cooperation Group 5 unhemolyzed 6 fresh serum collected in the fasting state is the preferred specimen 7 Li-Heparin / K2-EDTA / K3-EDTA / Citrat- Pasma 8 K2-EDTA / K3-EDTA / the use of EDTA-plasma may lead to slightly lower values 9 K2-EDTA / K3-EDTA / Li-Heparin
I ACET2 Acetaminophen Gen. 2 5µg/mL X24) X 23) X 23) I
eagents on cobas c 501 & c 311 & c 502 within specification up to within specification Lipemia ~mg/dl ~mg/dl ~mg/dl ~µmol/l ~µmol/l ~µmol/l Turbidity AAGP2 α1-acid Glycoprotein Gen.2 X X X 650 1000 60
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