Accelerator for medical applica/ons CAS 15
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1 Accelerator for medical applica/ons CAS 15 CAS Working group #2 Jenny Dueck (PSI) Sejla Mizic- Bajric (MedAustron) Dr. Viktor Iakovenko (Kiev InsGtute for Nuclear Research) Luis Mora Vallejo (CERN) Dr. Xander Janssen (VDL) Stefano BenedeO (CERN)
2 Introduc/on We have chosen Canada as the country for our hadron therapy facility We propose a facility for both carbon ion and proton therapy. Other ion species, with Q/m=1/2 (or slightly different, i.e. C11) could be used as well The accelerator technology that we propose is a full linear solu1on Given the absence of an available commercial facility, we propose a 2 years- long design study (same scheme of the PIMMS study), at the end of which a commi^ee will decide whether to turn into construcgon phase or to stop the project Budget has to be allocated for the design study (see dedicated slide) MAPLE Medical Accelerator for Protons and Light ions for ExGncGon of cancer
3 Number of pa/ents Total populagon 36.16M 62% South- East Ontario 22.4M South Quebec 1% Cancer pagent 224k 20% Radio therapy 44.8k 15% Hadron therapy 7k GPTC (NL) 600 p/y Scandion clinic (SE) 1000 p/y MedAustron (A) 1400 p/y 5 min/fracgon 12 fracgon/hour 12 hours/day 144 fracgon/day 250 days/year fracgon/year 20 fracgon/pagent 1800 pagents/year
4 ! Ra/onale of a full linear solu/on BEAM ENERGY. Can be varied acgvely, at the machine level, from pulse to pulse. 200 Hz repeggon rate is doable. BEAM QUALITY. No need of degraders, i.e. no beam size spreading. COST- EFFECTIVE SOLUTION. A 3- room facility (without gantries) would cost around 40 M (source: ADAM) COMPACT SOLUTION. Bo^om right picture has the footprint of CNAO.
5 Main design parameters Final beam energy: 450 MeV/u Energy variagon range: 70 MeV/u 450 MeV/u Average beam intensity: 1-2 na Spot size: FWHM adjustable 4 mm 12 mm Field size: 30 x 30 cm AcGve scanning, energy adjustable each 5 ms
6 Technical specifica/ons ION SOURCE. EBIS type. High frequency intense pulsed C6+ and other species. RepeGGon rate (eventually with two sources) up to 400 Hz. Pulse length: 5 µs. Number of ions per µs: 2e+8. Pulse stability: <5%. Beam emi^ance: 0.1 to 0.2 mm.mrad. INJECTOR. RFQ. Frequency: 750 MHz. Input energy: 20 KeV/u. Output energy: 2.5 MeV/u. Transmission: >95%. INTERMEDIATE β STRUCTURE. IH type. Frequency: 3 GHz. Output energy: 70 MeV/u. Transmission: >15%. FODO laoce: PMQs. HIGH β STRUCTURE. CCL type. Frequency: 3 GHz. Output energy: 450 MeV/u. Transmission: >95%. FODO laoce: PMQs. Transfer lines: 180 MEBT with two 90 SC (?) dipoles and quadrupole in between to close dispersion. HEBT. Straight HEBT à la MedAustron.
7 RF power consump/on es/ma/on W= Z LP CCL: Delta energy gain = 450 MeV/u 70 MeV/u = 380 MeV/u = 760 MeV Approx. length = 35 m Avg Shunt Impedance= 100 Mohm/m Peak power: 165 MW ish - > Avg. gradient 22 MV/m H- structure: Delta energy gain = 70 MeV/u 2.5 MeV/u = 67.5 MeV/u = 135 MeV Approx. length = 15 m Avg Shunt Impedance= 60 Mohm/m Peak power: 20 MW ish - > Avg. gradient 10 MV/m Total RF peak power ( with 1 MW RFQ) = 186 MW (225 with 20% wg losses) D.C. = 4 µs x 400 Hz = 1.6e- 3 Average RF power consump6on = 360 kw
8 RF power source M3 ScandiNova modulator K1 ScandiNova modulator KIU- 147/BAC No oil tank. Possibility to operate klystron at a distance No focusing solenoid (3 kw) Weight 90 kg Length 0.90 m
9 Timeline and business plan Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Design Study Construction Accelerator Installation Beam commisioning Acceptance tests Total costs Fixed Variable/running - Ground (3 ha) 15 - Maintenance / consumables 6 - Building 20 - Energy (2MW x 16h/d) 1 - Accelerator 25 - Personnel (120 persons) 8-2x Gantry 20 - PaGent hotel (100 pagents for 250 days) Commissioning incl personnel 10 - Treatment planning 7 - PaGent posigoning 10 - Imaging systems (1 MRI, CT, 1 PET- CT, 4 CBCT) 2 - Permits Decomissioning including removal of ac6vated material??? A Brahme et al. Nucl. Instr. And Meth. In Phys. Res. B um Fixed Total income Variable/running pagents x
10 Exper/se needed BOARD HR RadioprotecGon FDA cergficagons and quality Safety Clinical Dep. Radiotherapy Dep. Medical Physics Dep. Imaging Dep. Radiobiology Dep. Bioengineering Dep. AdministraGve Dep. Finance Dep. Infrastracture Dep. (Electr, Mech, IT ) Accelerator Dep. R&D Dep. OperaGon Dep. Maintenance Dep. Around 120 FTE (Full Time Equivalent) needed
11 Process map Manpower ConstrucGon Room # Gantry Power unit Accelerator Decision to build a hadron facility PR research MoGvaGon Proposal to build facility Budget Design Study ExperGse Budget Approval of the proposal Cure cancer Income, CuOng edge technology Imaging with protons Research PET Dosimetry RadiaGon protecgon and safety Environment Canada Health Canada Province permit to build Hydro Canada (Assessment of the power line) Ministry of economics ConstrucGon
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