Renewable Diesel: Fueling the Future in a Green Economy
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1 Renewable Diesel: Fueling the Future in a Green Economy Joel Velasco velasco@amyris.com May 13, 2011 [ 1 ]
2 Safe Harbor Summary This presentation includes forward-looking statements that are subject to many risks and uncertainties. These forward-looking statements, such as statements about Amyris s short-term and long-term growth strategies, total addressable market expectations, and efforts to develop and commercialize products, can sometimes be identified by use of terms such as intend, expect, plan, estimate, future, strive, and similar words. These statements involve many risks and uncertainties that may cause actual results to differ from what may be expressed or implied in these statements. These risks are discussed in Amyris s Securities and Exchange Commission filings and reports, including the risks identified under the section captioned Risk Factors in its annual report on Form 10-K filed March 14, 2011 and its quarterly report on Form 10-Q filed May 11, Amyris disclaims any obligation to update information contained in these forward-looking statements whether as a result of new information, future events, or otherwise. [ 2 ]
3 Amyris Leading the next generation of renewable products! Headquartered in California, Amyris is an integrated renewable products company focused on providing sustainable alternatives to a broad range of petroleum-based products.! Through our proprietary technology platform, we convert plant sugars into a variety of hydrocarbon molecules - flexible building blocks that can be used in a variety of markets, including cosmetics, flavors and fragrances, polymers, consumer products, renewable fuels and lubricants.! Our innovation is the practical integration of biology with chemistry to create novel solutions to address global, regional and local challenges. ANY BIOMASS FEEDSTOCK INDUSTRIAL SYNTHETIC BIOLOGY PLATFORM RENEWABLE CHEMICALS AND FUELS [ 3 ]
4 Building of our Technology Innovation from the lab to commercialization! Started in 2004 based on molecular engineering work from University of California - Berkeley Professor Jay Keasling s laboratory! Initially funded in 2005 by a grant from the Gates Foundation to develop a lower cost, consistent supply of artemisinin, key component of a malaria drug! Every year, malaria kills 1 million people mostly children under the age of five in Africa! Drugs exists but are in short supply and unaffordable to poorest populations! Expanded products to broad suite of petroleum replacements; issued patents covering diesel, jet, polymer and lubricant products Artemisia annua Annual Wormwood O O O Micrograph of fermentation fluids from production of Amyris Diesel H O H O H! Successful public offering in 2010 in the NASDAQ! Marketing and distribution channels to deliver products in the United States and other global markets Amyris engineered yeasts Diesel precursor [ 4 ]
5 Synthetic Biology The Technology of this Century Synthetic Biology: The Technology of this Century YEAST CELL ISOPRENOID PATHWAY ANTI-MALARIAL DRUG FARNESENE C-15 (DIESEL) SUGAR SOURCE ISOPRENE PINENE C-10 (JET FUEL) [ 5 ]
6 Our Vision How Amyris is enabling a bio-based economy Traditional Fossil Fuels Oil + Refinery Fermentation using Amyris engineered yeast = Petroleum products Hydro-processing Gasoline (Otto Cycle) Others to replace/reduce +20% Jet fuel 2020 est: 124 BGY ($300B) Bio-derived products Diesel 2020 est: 450 BGY ($800B) Chemicals Polymers, lubes & surfactants + = Hydrocarbon products Cosmetics Squalane & Fragances Biomass Sugars Amyris genetically engineered yeast Anti-malaria drug non-profit: treat over millions [ 6 ]
7 Amyris Platform Producing High-Value Products Through Low-Cost Fermentation High- Throughput Yeast Strain Design and Testing 2 LITER Research Emeryville, CA 300 LITER Pilot Plant Emeryville, CA 300 LITER Pilot Plant Campinas, Brazil 5,000 LITER 60, ,000 LITER 600,000 LITER Demo Facility Campinas, Brazil Contract Manufacturing (T&L in Illinois, Antibioticos in Spain & Biomin in Brazil) Capital Light Production São Martinho JV (Target Q2 2012) Operating [ 7 ]
8 Amyris Renewable Diesel Approved by EPA for 35% Blends Validated by external labs as a best-in-class product, meeting ASTM D975 fuel properties with zero sulfur. Cloud Point degrees Celsius Cetane Number Energy Density 1000 BTU/gal -9 to-30 Petroleum diesel Petroleum diesel Petroleum diesel Today s Biodiesel Today s Biodiesel 47 Today s Biodiesel 118 < 50 Amyris Amyris 58.6 Amyris Temperature below which wax in diesel form a cloudy appearance. Solidified waxes thickens the oil and clogs fuel filters and injectors in engines Measure of fuel s ignition delay higher cetane number has lower ignition delay Amount of energy stored per unit volume directly impacts miles per gallon (km per liter) Amyris diesel will be used in blends with conventional fuels; values shown for Amyris diesel is for biomass derived blending component. [ 8 ]
9 Amyris Renewable Diesel Significant reductions in NOx, PM, CO, and HC emissions - OEM validated % Amyris in Federal Diesel* % % Amyris FAME in CARB in Fed. Diesel* Diesel* % Amyris in Federal Diesel* % % Amyris FAME in CARB in Fed. Diesel* Diesel* NOx Change vs. Baseline 15% 10% 5% 0% -5% -10% -15% 5% 20% 50% 20% 20% -1.9% -4.7% -12% -0.11% +2.0% PM Change vs. Baseline 0% -2% -4% -6% -8% -10% -12% 5% 20% 50% 20% 20% -0.26% -1.5% -5.7% -3.1% -10.1% 0% 0% CO Change vs. Baseline -3% -6% -9% -12% -15% -2.1% -7.1% -15% -15% -11% HC Change vs. Baseline -5% -10% -15% -20% -25% -6.6% -3.6% -12% -20% -21% * Detroit Diesel Series 60 engine (5 gram NOx) no EGR, tested at SwRI May 2008 ** Source: EPA ( [ 9 ]
10 Amyris Renewable Diesel No Compromise Fuels: Drop-in and Better Performance! Derived using diverse, sustainable feedstocks Direct sugar to hydrocarbon fermentation! Hydrocarbons, not alcohols or esters Can be used in existing engines with no performance trade-offs Can be delivered using existing distribution infrastructure! Superior properties No sulfur Lower particulates, HC, CO and NOx Excellent cold flow characteristics Comparable energy density 80%+ lower GHG emissions than fossil fuels! OEM Validated Cummins Mercedes Benz Volkswagen Amyris diesel fuel (clear) in front; petroleum diesel (yellow) in the back [ 10 ]
11 Amyris Fuels Domestic feedstocks under evaluation with Dept of Energy! Syrups and Juice Sorghum Syrup (Ceres, USA) FL and TN Cane Syrup Florida-derived Sweet Sorghum Sugar Cane! Hydrolyzates Sorghum Bagasse NREL, USA, FL and TN Sorghum Bagasse [ 11 ]
12 U.S. R&D, Production & Processing Existing facilities in the United States [ 13 ]
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