Max Pressure (psi) Max Pressure (psi) Max Guidewire (in) Embolic Compatibility " Coils/ 0.018" HydroPearl. 800 ± 75 µm

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3 Progreat Microcatheters PROGREAT MICROCATHETER Includes hemostaticvalve and shaping mandrel Fr Size Product Code Length Pressure (psi) RO Markers Hydrophilic Coating Length MC"PB2411Y Fr MC"PB2413Y MC"PV2415Y MC"PC2711Y Fr 750 MC"PC2713Y MC"PB2811Y Fr MC'PB2813Y MC"PV2815Y PROGREAT COAXIAL MICROCATHETER SYSTEM Includes unique 0.021" GLIDEWIRE" GT, wire stopper, guidewire introducer, hemostatic valve, 2.5ml syringe and shaping mandrel Fr Size Product Code Length Pressure (psi) RO Markers Hydrophilic Coating Length 0.021" GLIDEWIRE"GT Length 2.7Fr MC"PE27111 Y 110 MC"PE27131 Y Fr MC"PE28111 YB 110 MC"PE28131 YB Fr MC"PE28151 YV PRODUCT SPECIFICATIONS Catheter OD Distal/ Proximal (Fr/mm) Length Inner Diameter (in/mm) Guidewire (in) Embolic Compatibility Dead Space Volume (ml) Actual Flow Rate (ml/sec) 750 psi 900 psi 2.4/2.9Fr (0.80/0.97mm) 150 cm 0.022",IJ.57m m 0.018" HydroPearl 600 ± 75 µm /2.9Fr (0.90/0.97mm) 0.025",IJ.65mm 0.021" HydroPearl 800 ± 75 µm /3.0Fr (0.93/1.00mm) 150 cm 0.027",1J.70mm 0.021" HydroPearl 800 ± 75 µm *Flow rates taken at 37 using ISO VUE 300. FIND OUT MORE I Phone: terumois.com e Fax: Terumo Medical Corporation. AJI r hts reserved. All bran d names are trademarks er registered trademarks of thbr respective cmners. ISOVUE 300 is a regetered trademark of BRACCO Diagnostics. PM RUMO INTERVENTIDNAL SYSTEMS

4 PROGREAT ALPHA EXPAND YOUR OPTIONS IN ACCESS & EMBOLIC DELIVERY PROGREAT ALPHA TM 2.0 Fr size for small peripheral vessels Designed to enhance access to small peripheral vessels 1,2 Low profile distal OD smallest microcatheter specifically for peripheral vasculature 1,2 TERUMO Glide Technology for navigation through tortuous anatomy 1,2 Designed to confidently deliver embolotherapy 3 Thin-wall design with large lumen 1,2 Tungsten coil reinforcement for kink resistance mm/0.019in DMSO compatible 4 Designed to improve the efficiency of your embolization procedures 2 Supports the delivery of large embolics up to 500 µm spherical particles, and the AZUR CX Peripheral Coil System 2 Designed to provide clear images, with superior PSI, compared to similar-sized microcatheters 1,2 0.67mm/2.0Fr Designed for small vessel embolization procedures such as: Prostate artery embolization (PAE) Pre Y-90 embolization Gastrointestinal bleeds

5 PUSHING BOUNDARIES Terumo Interventional Systems is committed to your success with innovative procedural solutions and ongoing support for your most challenging cases. We are relentlessly seeking new ways to help you apply effective solutions and achieve better outcomes for more patients. PROGREAT ALPHA TM 2.0 Fr Peripheral Microcatheter ORDERING INFORMATION PROGREAT ALPHA PERIPHERAL MICROCATHETER Fr SIZE 2.0 Fr PRODUCT CODE LENGTH MAX PRESSURE (PSI) RO MARKERS TIP SHAPE HYDROPHILIC COATING LENGTH MC*PC2011Y Straight 50 MC*PC2013Y Straight 70 MC*PC2015Y Straight 90 PRODUCT SPECIFICATIONS Catheter OD Distal/Proximal (Fr/mm) 2.0/2.7 Fr (0.67/ 0.90mm) LENGTH INNER DIAMETER (in/mm) MAX GUIDEWIRE (in) EMBOLIC COMPATIBILITY DEAD SPACE VOLUME (ml) ACTUAL FLOW RATE* (ml/sec) 750 psi 110 AZUR CX / Coils/ HydroPearl ± 75 μm *Flow rates taken at 37 using ISOVUE 300 Shapeable tip includes shaping mandrel PROGREAT MICROCATHETER Also available in 2.4 Fr / 2.7 Fr / 2.8 Fr (without guidewire) Includes hemostatic valve and shaping mandrel PROGREAT COAXIAL MICROCATHETER SYSTEM Available in 2.7 Fr / 2.8 Fr (coaxial type with catheter and guidewire) Includes unique GLIDEWIRE GT Guidewire, wire stopper, guidewire introducer, hemostatic valve, 2.5 ml syringe, and shaping mandrel References: 1. Catheter [Instructions for Use]. Somerset, NJ: Terumo Medical Corporation; Data on File. Terumo Medical Corporation. 3. PROGREAT Catheter 510(k); PROGREAT DMSO Compatibility Statement Letter. terumopublic/products/progreat/progreat_dmso_compatibility_statement_letter.pdf. September 8, Accessed July 28, Terumo Medical Corporation. All rights reserved. All brand names are trademarks or registered trademarks of their respective owners. PM-00114

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