Corporate Presentation

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1 Corporate Presentation

2 In a few words Contract Development & Manufacturing Organization Focused on key pharmaceuticals niches Independent company 32,8% owned by Management / 67,2% Private Equity funds Growing company 220 million Euros in 2014 and 1150 staff of Global company Products sold in more than 85 countries (USA / China / etc. ) Worldwide leader on BFS technology 2 Billon doses manufactured in 2014 Liquid Stick-pack pioneer Capacity of 260 Million liquid Stick-packs

3 History 1993 Acquisition of Amiens plant 1997 Start of Export activities 2005 Acquisition of Créapharm 2007 BFS Transfer from Boehringer Ingelheim 2011 FDA Inspection of Coutances plant 2013 Acquisition of Rochester Plant (NY USA) 1995 Focus on BFS technology 2002 Acquisition of Coutances Plant 2006 Launch of UNISTICK 2009 Acquisition of Colomiers plant 2011 Creation Commercial Office Unither do Brasil (Sao Paulo)

4 Equity Management Private equity funds 32,8 67,2 Private Equity Funds Equistone Parquest CIC Finance Picardie Investissements

5 Sales & Employees Revenues (k ) Employees

6 Global organization 5 Manufacturing sites Amiens France Colomiers France Coutances France Gannat France Rochester - USA Production Commercial Office 1 R&D center Bordeaux France Rochester, NY USA 3 Commercial Offices Paris France Rochester USA Sao Paulo - Brazil Sao Paulo BRAZIL

7 BFS Amiens France Coutances France Rochester USA Liquid Stick-Pack Colomiers France Rochester USA Global organization Production Commercial Office Bottles Colomiers France Rochester USA Rochester, NY USA Powder Stick-Pack Gannat France Effervescent Tablets Gannat France Sao Paulo BRAZIL Pharmaceutical Development Bordeaux France

8 European Locations FDA Approved BFS Coutances Amiens Paris (Commercial Office) Bordeaux Gannat Toulouse Powder Stick-Pack Effervescent Tablets Pharmaceutical Development Bottles Liquid Stick-Pack 8

9 TECHNOLOGIES Dedicated sites AMIENS France COUTANCES France COLOMIERS France GANNAT France ROCHESTER NY, USA BORDEAUX France PLANT m2 300 Staff of EU GMP / ISO m2 200 Staff of FDA / EU GMP / ISO m2 230 Staff of EU GMP / ISO m2 120 Staff of EU GMP / ISO m2 200 Staff of FDA GMP & EU m2 50 Staff of European GMP / ISO BFS (Sterile unit Doses) Liquid Stick-Pack Powder Stick-Pack Bottles Development Clinical batches Effervescent tablets EQUIPMENTS 10 BP Rotative 3 BP Alternative 1,5 Billion SDU / Year 8 BP Rotative 1 Billion SDU / Year 2 Stick-Pack Lines 250 Million Sticks / Year 5 Bottle Lines 50 Million bottles / Year Effervescent Line Powder Stick-Pack Line 450 Million tablets / Year Liquid Stick-Pack Line 1 BP Rotative line Bottle lines Capsules fillers & tablets presses Dry forms Primary packaging Drug delivery systems DEVELOPMENT 1 Dedicated team 1 Pilot workshop 1 Dedicated team 1 Pilot workshop (2015) 1 Dedicated team 1 Pilot workshop 1 Dedicated team 1 Pilot workshop 1 Dedicated team 1 Pilot workshop Formulation Validation Analytics Stability studies Quality control

10 Amiens - France TECHNOLOGY BFS (Sterile unit Doses) PLANT 13,700 m2 300 Staff of 3 & 5 shifts European GMP / ISO EQUIPMENTS 10 BP Rotative 3 BP Alternative 1.5 Billion SDU / Year Development 1 dedicated team 1 Pilot workshop

11 Coutances - France TECHNOLOGY BFS (Sterile unit Doses) PLANT 15,000 m2 200 Staff of 3 & 5 shifts FDA / European GMP / ISO EQUIPMENTS 8 BP Rotative 1 Billion SDU / Year Development 1 dedicated team 1 pilot workshop (2015)

12 Colomiers - France TECHNOLOGY Liquid Stick-Pack Bottles PLANT 17,000 m2 230 Staff of 2, 3 & 5 shifts European GMP / ISO EQUIPMENTS 3 Stick-Pack Line 250 Million Sticks / Year 5 Bottle Lines 50 Million bottles / Year Development 1 dedicated team 1 Pilot workshop

13 Gannat - France TECHNOLOGY Effervescent tablets Powder Stick-Pack PLANT 10,000 m2 100 Staff of 2 & 3 shifts European GMP / ISO EQUIPMENT Effervescent Line Powder Stick-Packs Line 450 Million tablets / Year Development 1 dedicated team

14 Rochester - USA TECHNOLOGY BFS (Sterile unit Doses) Liquid Stick-Pack Bottles / Powder PLANT 40,000 m2 200 Staff of US & European GMP EQUIPMENT Liquid Stick-Pack Line 1 BP Rotative line 2 Bottle lines/tablets presses & capsules fillers Development 1 dedicated team 1 Pilot workshop

15 R&D center Pharmaceutical Development Clinical batches Bordeaux - France Plant 1,800 m2 50 Persons European GMP / ISO Formulation and Clinical Batches Dry forms Primary Packaging Drug delivery systems Analytic Development Validation ICH Stability Quality Control

16 Our Mission To deliver to our customers Innovative Solutions Focus on key pharmaceuticals niches Competitive Solutions Dual Business Model Sustainable Solutions Partnership

17 Collaboration type Dual Business model Contract Development and Manufacturing Organization for strategy outsourcing Turn-key products & Dossiers for licensing in

18 Our Technologies Liquid Stick-Pack Technology Blow-Fill-Seal Technology CONSULTING PHARMACEUTICAL DEVELOPMENT Powder Stick-Pack Technology Bottle Technology INNOVATIVE SOLUTIONS MANUFACTURING Effervescent tablet Technology

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