Thermo Scientific HyPerforma Single-Use Mixer DS 300. Achieve greater. process flexibility

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1 Thermo Scientific HyPerforma Single-Use Mixer DS 300 Achieve greater process flexibility

2 Increased mobility smaller footprint The Thermo Scientific HyPerforma Single-Use Mixer DS 300 (S.U.M.) is built upon the proven legacy design of our single-use mixer and docking station S.U.M. It has been optimized for lower-cost, high throughput applications. The smaller footprint and lighter weight of the HyPerforma S.U.M. DS 300 provide mobility and flexibility in mixing applications not currently available in the market. Technology Modular mixing for enhanced process efficiency The HyPerforma S.U.M. DS 300 is a modular mixing station with purposely designed features. Mobility this ergonomically designed mixing station provides enhanced ease of use. Modularity choose from multiple drum sizes, mixing shafts and mixing head heights to configure the modular solution for your bioprocessing applications. Interoperability specifically designed to combine mixing across multiple scales in one mixing station by attaching to drums of four different sizes (50, 100, 200, and 300L). The system utilizes a top-mounted mixing motor with an angular drive shaft. This industry-accepted design eliminates vortices, ensures efficient mixing and provides more power. 2

3 Applications Preparation has never been simpler The S.U.M. DS 300 can be used in powderliquid and liquid-liquid mixing applications. By integrating our proven technology, you can use the same top-mounted mixing design to assure quality and eliminate the need for multiple mixers in your processes. The same system can be used for: Hydration powdered media and buffers Sterile mixing buffer solutions, cell culture media with sera and reagents, or other process fluids Pooling sterile liquid fractions 3

4 Benefits Do more with less Investment capital and space are precious resources the S.U.M. DS 300 addresses both. Reduce capital investment across multiple mixing applications by docking and mixing in multiple plastic drums Adapt your process with 50, 100, 200 and 300L sizes of mixing drums Mix efficiently at lower volumes with the 5:1 turndown ratio Direct drive design drastically reduces particulate generation Increase mobility with a smaller footprint and lighter weight Capable of open- and closed-top mixing Suitable for both powder-liquid and liquid-liquid applications Utilize S.U.M. BioProcess Containers from our world-class single-use film portfolio 4

5 Accessories Create the custom solution that meets your needs Plastic Drums Mix and move Use all or a few of the portable, plastic drums in the sizes that you need. These multi-functional drums are easily moved to cold rooms and stored until you need them. BioProcess Containers Ship and store Implement industry-proven Thermo Scientific BPC systems in the overall process of shipping and storing your liquid-liquid and powder-liquid bioprocess mixing applications. BPC liners come in open-and closed-top design, are manufactured using our high-performance single-use film and easily fit in every plastic drum size. Find out more about the S.U.M. DS 300 The complete S.U.M. DS 300 mixing platform consists of a portable mixing station, a drum, and a BPC. To learn more about the entire platform or to request a demo, please visit our website: thermoscientific.com/sumds300 5

6 Specification All you need to know about the S.U.M. DS 300 and its accessories S.U.M. DS 300 Electrical Power Supply Requirement (voltage, frequency, phase) Input Amperage Footprint VAC, 50-60Hz, single phase 15 amps 76.2cm (30 ) Wide x 86.4cm (34 ) Deep Height 122.4cm (48.2 ) Low 162.4cm (63.9 ) High Weight Control Box 398lbs (180kg) Built to IP65 standards Lift Range 400mm (15.75 ) Flow Type Mixing Rate Impeller to BPC Location Impeller (quantity x blade count) Counterclockwise Mixing Flow Direction Mixing Containers Radial/Axial rpm 5:1 off center 1 x 3 Down-pumping Drum Size 50L 100L 200L 300L Turndown Ratio 5:1 5:1 5:1 4:1* Footprint (D x H) Hardware Material Impeller Sleeve Impeller Material Impeller Sleeve with Quick Connect *5:1 turndown ratio with adjustable motor head 60 x 58cm (23.5 x 23 ) USP Class VI, HDPE C-Flex tubing 60 x 76cm (23.5 x ) Plastic (LLDPE) 60 x 114cm (23.5 x ) 61 x 122cm (24 x 48 ) 6

7 Options Place your order from the options below S.U.M. DS 300 Product Number Description SUMDS DS 300 Units; VAC 50-60Hz SUMDS DS 300 Units; VAC 50-60Hz with Drum Positioner SUMDS DS 300 Units; VAC 50-60Hz with Adjustable Motor Head SUMDS DS 300 Units; VAC 50-60Hz Drum Locator and Adjustable Motor Head Drums SH L SH L Drum with bottom drain port SH L SH L Drum SH L-200L Support plate for drum drain port Drum Dollies SH L-200L Plastic Dolly (Single Pack) SH L-200L Plastic Dolly (2-Pack of SH ) SH L Stainless Steel Dolly BPC Tank Liners, Irradiated SH L SH L Open top, bottom drain SH L SH L Open top, top drain BPC Tank Liners, Non-irradiated SH L SH L Open top, bottom drain SH L BPC Tank Liners, Irradiated SH L SH L Closed top, bottom drain SH L Impeller Sleeve SH L, 35.3cm (13.9 ) SH L, 53.1cm (20.9 ) SH L, 77.0 cm (30.3 ) For use with open-top liners SH L, 94.9cm (37.8 ) Reuseable Hub SV L For use with impeller sleeve and open-top liners 7

8 Integrated Solutions for BioProduction Single-Use Mixers (S.U.M.) A variety of options up to 2000 L for both upstream and downstream applications. Powdered & Liquid Media We offer both custom manufacturing and a full range of standard media and supplement products. BioProcess Containers A variety of configurations up to 2000 L for liquid harvest, storage, and transportation. Sera Our serum is the industry standard for consistent quality and reliability. Single-Use Bioreactors (S.U.B.) L bioreactor capacity capable of integrating with an existing control system. Buffers & Process Liquids Custom and standard buffers and process liquids, including WFI Quality Water. Contact your Thermo Scientific HyClone product representative for more information. Cell Culture and BioProcessing In the Americas and Asia 925 West 1800 South Logan, Utah USA Tel: +1 (435) Toll-Free: +1 (800) Fax: +1 (435) thermoscientific.com/sumds300 In Europe Industriezone III, Industrielaan Erembodegem Belgium Tel: Fax: SM Thermo Fisher Scientific Inc. All rights reserved. C-Flex is a registered trademark of Saint- Gobain Performance Plastics. All other trademarks are the property of Thermo Fisher Scientific Inc.