e- 생물산업 29 권 3 호 / 2016 년 5 월
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![e- 생물산업 29 권 3 호 / 2016 년 5 월 한국미생물 생명공학회웹진 [ 신진과학자 ] 이주영 (Lee, Ju Young) 한국화학연구원바이오화학연구센터 E-mail: juylee@krict.re.](/docs-images/92/108332989/images/1-0.jpg "kr [ 약력 ] 1998-2003 경북대학교유전공학과 ( 학사 ) 2003-2005 KAIST 생명과학과 ( 석사 ) 2005-2010 KAIST 생명과학과 ( 박사 ) 2010-2015 삼성전자종합기술원바이오소재랩 ( 전문연구원 ) 2015-2015 삼성바이오에피스세포주그룹 ( 책임연구원 ) 2016-현재 한국화학연구원바이오화학연구센터 ( 선임연구원")
1 e- 생물산업 29 권 3 호 / 2016 년 5 월 한국미생물 생명공학회웹진 [ 신진과학자 ] 이주영 (Lee, Ju Young) 한국화학연구원바이오화학연구센터 juylee@krict.re.kr [ 약력 ] 경북대학교유전공학과 ( 학사 ) KAIST 생명과학과 ( 석사 ) KAIST 생명과학과 ( 박사 ) 삼성전자종합기술원바이오소재랩 ( 전문연구원 ) 삼성바이오에피스세포주그룹 ( 책임연구원 ) 2016-현재 한국화학연구원바이오화학연구센터 ( 선임연구원 ) [ 연구분야 ] 고효율플랫폼균주개발연구 대장균의 phenotype engineering을위한 zinc finger 단백질기반의 artificial transcription factors tool 개발 유전체재설계를통한최소유전체플랫폼대장균개발 고부가대사산물 / 바이오의약품대량생산맞춤형균주개발 1
2 미생물기반정밀 / 특수기능성화학, 식품, 화장품, 의약물질생산연구 대장균기반바이오에너지 ( 부탄올 ) 생산연구 Yeast를이용하여바이오플라스틱전구체 (Lactic acid) 대량생산연구 대장균기반항체의약품고효율 / 대량생산플랫폼기술개발연구 [ 연구성과 ] Le Minh Bui, Ju Young Lee, Almando Geraldi, Ziaur Rahman, Jun Hyoung Lee and Sun Chang Kim (2015) Improved n-butanol tolerance in Escherichia coli by controlling membrane related functions. J. Biotechnol., 204, Ju Young Lee, Chang Duk Kang, Seung Hyun Lee, Young Kyoung Park and Kwang Myung Cho (2015) Engineering cellular redox balance in Saccharomyces cerevisiae for improved production of L-lactic acid. Biotechnol. Bioeng., 112, Su A Jang, Hyun Kim, Ju Young Lee, Ju Ri Shin, Da Jung Kim, Ju Hyun Cho and Sun Chang Kim (2012) Mechanism of action and specificity of antimicrobial peptides designed based on buforiniib. Peptides, 34, Ju Young Lee, Kyung Seok Yang, Su A Jang, Bong Hyun Sung and Sun Chang Kim (2011) Engineering butanol-tolerance in Escherichia coli with artificial transcription factor libraries. Biotechnol. Bioeng., 108, Ju Young Lee, Bong Hyun Sung, Byung Jo Yu, Jun Hyoung Lee, Sang Hee Lee, Mi Sun Kim, Michael D. Koob and Sun Chang Kim (2008) Phenotypic engineering by reprogramming gene transcription using novel artificial transcription factors in Escherichia coli. Nucleic Acids Res., 36: e102. 2
3 Bong Hyun Sung, Choong Hoon Lee, Byung Jo Yu, Jun Hyoung Lee, Ju Young Lee, Mi Sun Kim, Frederick R. Blattner and Sun Chang Kim (2006) Development of a biofilm production-deficient Escherichia coli strain as a host for biotechnological applications. Appl. Environ. Microbiol., 72, Byung Jo Yu, Bong Hyun Sung, Ju Young Lee, Sung Hwa Son, Mi Sun Kim and Sun Chang Kim (2006) sucab and succd are mutually essential genes in Escherichia coli. FEMS Microbiol. Lett., 254, Ju Young Lee, Chang Duk Kang, Ji Yoon Song, Seung Hyun Lee, Jin Hwan Park and Kwang Myung Cho (2014) Yeast cell producing lactate comprising reduced activity of rim15 and igo2, method of producing yeast cell and method of producing lactate using the same. P Ji Yoon Song, Chang Duk Kang, Joon Song Park, Sung Soo Kim, Young Kyoung Park, Sung Haeng Lee, So Young Lee, Ju Young Lee, Kwang Myung Cho and Woo Yong Lee (2014) Genetically engineered yeast cell producing lactate including acetaldehyde dehydrogenase, method of producing yeast cell, and method of producing lactate using the same. P Woo Yong Lee, Chang Duk Kang, Ju Young Lee and Kwang Myung Cho (2014) Polypeptide conferring acid tolerant property to yeast cell, polynucleotide encoding the same, yeast cell having increased amount of the polypeptide, method of producing a product by using the yeast cell, and method of producing acid-tolerant yeast cell. US14/ Young Kyoung Park, Chang Duk Kang, Ji Yoon Song, Ju Young Lee, Seung Hyun Lee and Kwang Myung Cho (2014) Yeast cell with increased 3
4 pyruvate pool in cytosol and method of producing pyruvate-based metabolite using the same. US14/ Sung Soo Kim, So Young Lee, Chang Duk Kang, Ju Young Lee and Kwang Myung Cho (2014) Yeast cell with activated lactate dehydrogenase and method of producing lactate using the yeast cell. US14/ Ju Young Lee, Hyun Min Koo, Jae Chan Park, Jie Un Kim, Joon Song Park, Soon Chun Chung and Byung Kwan Cho (2014) Acid-resistance in Kluyveromyces marxianus by engineering transcriptional factor. US14/ Hui Sub Lim, Sung Soo Kim, Ji Yoon Song, So Young Lee, Ju Young Lee and Kwang Myung Cho (2014) Genetically engineered and acid resistant yeast cell with ehanced radiation sensitivity complementing kinase activity and method for producing lactate using the same. P Ju Young Lee, Chang Duk Kang, Jin Kyu Kang, Seung Hyun Lee and Kwang Myung Cho (2014) Yeast cell with inactivated NADH dehydrogenase and method of producing lactate using the yeast cell. US14/ Hyun Young Shin, Chang Duk Kang, Ju Young Lee, Seung Hyun Lee and Kwang Myung Cho (2014) Yeast cell with reduced pentose phosphate pathway and method for producing lactate using the same. P Ju Young Lee, Hyun Young Shin, Chang Duk Kang, Seung Hyun Lee and Kwang Myung Cho (2014) Acid resistant yeast cell with reduced fps1 activity and method for producing lactate using the same. P Soon Chun Chung, Hyun Min Koo, Ji Eun Kim, Jae Chan Park, Joon Song Park and Ju Young Lee (2014) Method of construction of recombinant organisms using multiple genes co-integration. US14/
5 Jae Young Kim, Jin Kyu Kang, Chang Duk Kang, Sung Soo Kim, Jae Chan Park, Byung Jo Yu, Ju Young Lee and Hui Sub Lim (2014) Microorganism over-expressing lactic acid transporter gene and having inhibitory pathway of lactic acid degradation, and method of producing lactic acid using the microorganism. US A1. Jae Young Kim, Jin Kyu Kang, Chang Duk Kang, Sung Soo Kim, Ju Young Lee, Hyun Ah Kang, Jae Chan Park, Hui Sub Lim and Jin Ho Choo (2013) Cassette including promoter sequence of target gene and method of gene manipulation using the same. US A1. Young Kyoung Park, Chang Duk Kang, Ji Yoon Song, Ju Young Lee, Seung Hyun Lee, Kwang Myung Cho (2013) Yeast cell with inactivated or depressed pyruvate carboxylase and method of producing latate using the same. P Sung Soo Kim, Ji Yoon Song, Chang Duk Kang, Ju Young Lee, Seung Hyun Lee and Kwang Myung Cho (2013) Yeast cell with inactivated glycerol-3- phosphate dehydrogenase and activated glyceraldehyde-3-phosphate dehydrogenase and method of producing lactate using the same. P Ju Young Lee, Chang Duk Kang, So Young Lee, Young Kyoung Park, Ji Yoon Song, Seung Hyun Lee and Kwang Myung Cho (2013) A genetically engineered yeast cell capable of producing lactate, a method for producing the same, and a method for producing lactate using the cell. P Hwa Young Jo, Byung Jo Yu, Jae Chan Park, Sung Min Park, Hyun Min Goo and Ju Young Lee (2012) High throughput screening of lactic acidproducing microorganism. US13/
6 Sun Chang Kim, KuiHyeon Kang, Byung Jo Yu, Jun Hyoung Lee, Bong Hyun Sung, ChoongHoon Lee, Sang Hee Lee, Ju Young Lee and MyungKeun Park (2008) A recombinant vector for deleting specific regions of the chromosome and a method for deleting specific chromosomal regions of chromosome in the microorganism using the same. EP B1. Sun Chang Kim, Su A Jang, Jung Min Kim, Bong Hyun Sung, Ki Jung Lim, JuRi Shin and Ju Young Lee (2008) Method for the mass expression of a antimicrobial peptide by using a translational coupling system. US B2. Sun Chang Kim, Ju Young Lee, Bong Hyun Sung, Jun Hyoung Lee, Sang Hee Lee and KuiHyeon Kang (2006) A preparation of an artificial transcription factor comprising zinc finger protein and transcription factor of prokaryote, and a use thereof. US B2. 6
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