Class II biological safety cabinets
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1 Bulletin No Class II biological safety cabinets Advanced technology for personnel, environment and product protection
2 Applications Biological safety cabinets are defined in Australian standard AS as the primary barrier against exposure to aerosols that may be produced from common microbiology procedures. In addition to protection for personnel and the room environment, many work programmes require that products are protected from airborne contamination. Ultima series cabinets provide personnel, environment and product protection in applications involving hazardous biological agents which AS classifies in Risk Groups 2 and 3. These cabinets are not designed for use with biological agents of extreme hazard. For applications involving cytotoxic drugs, CG2000 Series Cytogard cabinets (AS2567) should be specified. Australian Standards AS2252, Part 2 specified requirements for Class II cabinets, and AS is a guide to their installation and use. Test procedures for safety cabinets are described in AS1807. Ultima Series cabinets are designed and manufactured to comply with AS2252, Part 2, and each cabinet is factory certified by a NATA Accredited laboratory to meet the specified performance requirements. Description Ultima Series cabinets are part-recirculating laminar air flow enclosures with high efficiency particulate air (HEPA) filtration of exhaust air and an air barrier at the work opening. HEPA filtered vertical laminar air flow which is recirculated in the work zone creates an ultra-clean work environment for product protection. An air barrier between the operator and the work zone is maintained by a flow of room air into a full-width grille in the work opening. The barrier air mixes with the laminar flow air in a sump underneath the work surface, and is exhausted via a HEPA filter. All positive pressure zones and filter seals are surrounded by negative pressure zones, so as to contain potentially hazardous aerosols. Purchasers may specify cabinet exhaust discharge on the right-hand side, left-hand side, front or top. Cabinets are produced with work zone width of 90cm, 120cm and 180cm, and may be installed on standard laboratory benches or on optional floor stands. Embodying advanced system monitoring technology, enhanced ergonomics and styling, The Ultima Class II sets a new standard in safety cabinet design and performance. Construction Cabinet. Constructed in electro-galvanised steel with joints welded using a gas-shielded arc process. This method produces a robust, gas-tight housing which is able to withstand the rigours of transport and handling. Exterior finish is in a special baked enamel which had been developed for laboratory equipment. Work zone. Constructed in Grade 304 stainless steel with 2B finish. Corners are radiused and crevice-free for ease of cleaning and all surfaces are carefully dressed to remove sharp edges. The removable work tray is designed to allow cleaning access to its underside without removing it from the cabinet. A removable panel provides cleaning and service access to the rear plenum. A pneumatic mechanism assists the opening and closing of the viewing window without the need for external fasteners or catches. The window is self supporting in the fully-opened position to facilitate cleaning and access for large items. Opening the window with the cabinet running automatically engages a boost mode for enhanced containment by activating maximum exhaust airflow and the alarm systems.
3 Electrical and diagnostics. Cabinets operate on a single-phase 240V, 50 Hz power via a 10A outlet. Alternative electrical specification is available for overseas installations. The electrical system complies with Australian Standard AS3100. Fans. Separate direct-drive fans are provided for the exhaust and laminar flow HEPA filters. Fans are speed-controlled to enable airflows to be maintained through filter life. The fan control circuits are interlocked so that the laminar flow system will not operate until the exhaust system has achieved containment condition. An audible alarm with rechargeable battery back-up and visible indicators signify any reduction in airflows. A manometer gauge located in the work zone monitors fan / filter system pressures. HEPA Filters. Clyde-Apac Microseal HEPA filters are designed and manufactured to comply fully with AS4260 and are classified in this standard as Grade 2. Each filter is individually certified to achieve an arrestance efficiency of not less than % to the stringent BS3948 Sodium Flame test and to be leak-free in accordance with AS All testing is conducted in a NATA-Accredited factory laboratory and a NATA-endorsed test label, being an extract of the test report, is affixed to each filter. A low-voltage touch-control panel is located on the front of the cabinet. The Optima 2000 microprocesor controlled control and diagnostic system provides continous monitoring of critical cabinet functions with a digital display indicating the nature of any malfunction. The boost mode and a post-use over-run mode may be manually selected from the control panel. A real-time clock in the control panel may be programmed to function as an experiment timer. An integral fluorescent lamp housing reduces heat build-up near the operator. Glare-free lamps provide a minimum lighting intensity of 800 lux at the work floor. A germicidal UV lamp provides radiation intensity of not less than 400mW/m2. A splashproof power outlet is fitted in the work zone. Note: 1. For activated carbon exhaust filter option, width (W) on the side exhaust and the (H) on the top exhaust cabinets will increase by 260mm and that the front exhaust can not be fitted with this option. 2. The exhaust discharge recommended clearance is 600mm 3. Stand height is nominally 900mm
4 Standard Features Optima 2000 programmable control and diagnostics system with digital display Low-voltage touch controls Real-time clock and experiment timer Alarms and boost mode automatically engaged when viewing window is open Boost mode selectable at control panel Selectable post-use over-run timer Germicidal UV lamp with automatic switch-off timer Provision for interface with building management systems Pneumatically-assisted viewing window Hourmeter to record operating time Magnehelic gauge to monitor fan systems Splashproof power outlet in work zone Stainless steel work opening cover Comprehensive operation and maintenance manual Options Additional power outlet Glass sides Floor stand Gas tap with.02um filter Activated-carbon exhaust filter Fumigation adaptor panels for work opening and exhaust On site testing Ultima series cabinets are factory-tested and certified by a NATA-registered laboratory. Additional testing and certification is recommended as follows: (a) On site prior to use (b) After any electrical or mechanical maintenance (c) After filter replacement (d) After re-location (e) At least annually (f) In special circumstances, e.g. if faulty operation is suspected. Control Panel 1. Fan/post use over run switch 2. Power outlet switch 3. Gas reset switch* 4. Fluorescent light switch 5. UV lamp switch* 6. Boost mode switch 7. Display panel 8. Mains power indicator 9. Alarm indicator *optional function
5 AES Environmental Laminar Flow Service AES Environmental, a NATA-Accredited laboratory, provides comprehensive on-site maintenance, testing and certification services for safety cabinets, laminar flow work stations, cleanrooms and HEPA filter installations. This service is available from fully-equipped laboratories in major Australian centres. Similar services are provided by appointed service agents in other regions. Quality control Clyde-Apac laminar flow and HEPA filter products are manufactured in Australia by AES Environmental, under an accredited Quality Management system that complies with the international standard ISO 9001:2008. Other products HWS Series horizontal laminar flow cabinets VWS Series vertical laminar flow cabinets BSC2000 Class I biological safety cabinets CG2000 cytotoxic drug safety cabinets PCR laminar flow cabinets Recirculating fume cabinets TFP Series HEPA filter cleanroom modules A Division of AES Environmental 9A Pembury Road, Minto NSW 2566 Visit us at: Distributors throughout Asia For all enquiries please contact us on; Phone: Fax: sales@clydeapac.com.au Note: In keeping with our policy of continuing product improvement, we reserve the right to alter specifications without notice Clyde Apac 2015 Bulletin No REV2
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