Table of Contents. FlexGro Rocker Style Biocontainer Assemblies... Standard Port Options L FlexGro Biocontainer Assemblies...

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Table of Contents FlexGro Rocker Style Biocontainer Assemblies... Biocontainer s Standard Port Options... Basic Option Expanded Basic Option Standard Option 0 L FlexGro Biocontainer Assemblies... Basic Option Expanded Basic Option Standard Option 20 L FlexGro Biocontainer Assemblies... Basic Option Expanded Basic Option Standard Option 22 L FlexGro Biocontainer Assemblies... Basic Option Expanded Basic Option Standard Option 50 L FlexGro Biocontainer Assemblies... Basic Option Expanded Basic Option Standard Option 3 3 5 5 6 7 8 8 9 0 2 3 5 6 2

FlexGro Biocontainer Assemblies FlexGro rocker style biocontainer assemblies are ideal for various cell culture applications and can be ordered from our standards portfolio in 0, 20, 22 and 50 liter nominally rated volumes that accommodate working volumes up to 25 liters. FlexGro assemblies can be deployed on common rocking hardware. FlexGro biocontainers are manufactured from Meissner s ultraclean TepoFlex polyethylene (PE) based multi-layer film. TepoFlex PE film delivers an exceedingly low extractables profile and is devoid of slip agents, providing robust and repeatable performance for your cell culture process. It is the ideal choice for cell cultivation in process development, small scale production and seed train applications. FlexGro biocontainer assemblies can be easily customized to include specific sampling and process connections, as well as tubing and port options, to cater to your process. Meissner also offers complementary products, such as FlexFill assemblies which cater to applications that require aseptic fluid transfer from a bottle to a single-use system, and multi-stage filtration assemblies that are optimized for harvest applications. More information can be found at www.meissner.com/flexfill. Our applications engineering team can assist in both the customization of a FlexGro biocontainer assembly for your specific needs, as well an overall optimization of your process from inoculation to harvest. Biocontainer s Nominal Biocontainer Working * GE Healthcare Sartorius Stedim Biotech 0 L 0.5 L - 5 L System 2/0, System 20/50 with Kit 20 RM 20/50 with Holder 20 20 L L - 0 L System 20/50 with Kit 20 RM 20/50 with Holder 20 22 L L - 0 L System 20/50 with Kit 50 N/A 50 L 5 L - 25 L System 20/50 with Kit 50 N/A * Working volume is a maximum 50% of nominal biocontainer volume. 3

FlexGro Biocontainer Assemblies Basic Option Meissner s Basic Option for the FlexGro biocontainer assembly includes ports: a gas inlet filter, an outlet vent filter with a check valve, a needleless sampling or inoculation port and a weldable line with an MPC fitting, which is often used for media feed or harvest applications. Port Port 2 Port 3 Port Inlet Air Filter Outlet Air Filter, Check Valve 2" Tubing (5. cm Tubing), Needleless Sampling Valve 0" Length (0.6 cm Length), /" x 7/6" TPE Tubing (6. mm x. mm TPE Tubing), Female QDC + Plug 2 Expanded Basic Option Meissner s Expanded Basic Option for the FlexGro biocontainer assembly includes 5 ports: a gas inlet filter, an outlet vent filter with a check valve, a needleless sampling or inoculation port, a weldable line with an MPC fitting, which is often used for media feed or harvest applications, and an additional smaller bore weldable line with luer connectivity via a female luer fitting. Port Port 2 Port 3 Port Port 5 Inlet Air Filter Outlet Air Filter, Check Valve 2" Tubing (5. cm Tubing), Needleless Sampling Valve 0" Length (0.6 cm Length), /" x 7/6" TPE Tubing (6. mm x. mm TPE Tubing), Female QDC + Plug 0" Length (0.6 cm Length), /8" x /" TPE Tubing (3.2 mm x 6. mm TPE Tubing), Female Luer + Plug 3 Standard Option Meissner s Standard Option for the FlexGro biocontainer assembly includes 6 ports: a gas inlet filter, an outlet vent filter with a check valve, a needleless sampling or inoculation port, a weldable line with an MPC fitting, which is often used for media feed or harvest applications, and two additional lines with luer connectivity via a female luer fitting one is a smaller bore weldable line and the other provides minimal hold up volume. Port Port 2 Port 3 Port Port 5 Port 6 Inlet Air Filter Outlet Air Filter, Check Valve 2" Tubing (5. cm Tubing), Needleless Sampling Valve 0" Length (0.6 cm Length), /" x 7/6" TPE Tubing (6. mm x. mm TPE Tubing), Female QDC + Plug 0 Length (0.6 cm Length), /8 x / TPE Tubing (3.2 mm x 6. mm TPE Tubing), Female Luer + Plug 2" Tubing (5. cm Tubing), Female Luer + Plug

Basic 0 L FlexGro Biocontainer TepoFlex Acrylic/ 3 3/6" x 3/8" Tubing, 2" Length (.8 mm x 9.5 mm Tubing, 5. cm Length) Platinum-Cured 5 Slide Clamp, Medium HDPE 3 6 Male Luer Cap Polycarbonate 7 Swabable Valve / Needleless Injection Site Polycarbonate/ 8 /" Hose Barb x Female Luer Adapter 9 Ratchet Pinch Clamp, Medium 0 /" x 7/6" Tubing, 0" Length (6. mm x. mm Tubing, 0.6 cm Length) Coupling Body, /" Hose Barb, MPC (Coupling Body, 6. mm Hose Barb, MPC) Polycarbonate 2 Sealing Plug, MPC Polycarbonate DRA305B-N0-B025-0 0 L Basic FlexGro Assembly 0.5 L 5 L 5

Expanded Basic 0 L FlexGro Biocontainer TepoFlex Acrylic/ 3 3/6" x 3/8" Tubing, 2" Length (.8 mm x 9.5 mm Tubing, 5. cm Length) Platinum- Cured 5 5 Slide Clamp, Medium HDPE 3 6 Male Luer Cap Polycarbonate 7 Swabable Valve / Needleless Injection Site Polycarbonate/ 8 /" Hose Barb x Female Luer Adapter 9 /" x /8" Hose Barb Reduction Fitting (6. mm x 3.2 mm Hose Barb Reduction Fitting) 0 Ratchet Pinch Clamp, Small /8" x /" Tubing, 0" Length (3.2 mm x 6. mm Tubing, 0.6 cm Length) 2 /8" Hose Barb x Female Luer Adapter (3.2 mm Hose Barb x Female Luer Adapter) 3 Male Luer Plug Protective Cover, Small Vinyl 5 Ratchet Pinch Clamp, Medium 6 /" x 7/6" Tubing, 0" Length (6. mm x. mm Tubing, 0.6 cm Length) 7 Coupling Body, /" Hose Barb, MPC (Coupling Body, 6. mm Hose Barb, MPC) Polycarbonate 8 Sealing Plug, MPC Polycarbonate DRA5305B-N0-B025-0 0 L Expanded Basic FlexGro Assembly 0.5 L 5 L 6

Standard 0 L FlexGro Biocontainer TepoFlex Acrylic/ 3 3/6" x 3/8" Tubing, 2" Length (.8 mm x 9.5 mm Tubing, 5. cm Length) Platinum- Cured 6 5 Slide Clamp, Medium HDPE 6 Protective Cover, Small Vinyl 2 7 Male Luer Plug Polypropylene 2 8 /" Hose Barb x Female Luer Adapter Polypropylene 2 9 Male Luer Cap Polycarbonate 0 Swabable Valve / Needleless Injection Site Polycarbonate/ /" x /8" Hose Barb Reduction Fitting (6. mm x 3.2 mm Hose Barb Reduction Fitting) 2 Ratchet Pinch Clamp, Small 3 /8" x /" Tubing, 0" Length (3.2 mm x 6. mm Tubing, 0.6 cm Length) /8" Hose Barb x Female Luer Adapter (3.2 mm Hose Barb x Female Luer Adapter) 5 Ratchet Pinch Clamp, Medium 6 /" x 7/6" Tubing, 0" Length (6. mm x. mm Tubing, 0.6 cm Length) 7 Coupling Body, /" Hose Barb, MPC (Coupling Body, 6. mm Hose Barb, MPC) Polycarbonate 8 Sealing Plug, MPC Polycarbonate DRA6305B-N02-B025-0 0 L Standard FlexGro Assembly 0.5 L 5 L 7

Basic 20 L FlexGro Biocontainer TepoFlex Acrylic/ 3 3/6" x 3/8" Tubing, 2" Length (.8 mm x 9.5 mm Tubing, 5. cm Length) Platinum-Cured 5 Slide Clamp, Medium HDPE 3 6 Male Luer Cap Polycarbonate 7 Swabable Valve / Needleless Injection Site Polycarbonate/ 8 /" Hose Barb x Female Luer Adapter 9 Ratchet Pinch Clamp, Medium 0 /" x 7/6" Tubing, 0" Length (6. mm x. mm Tubing, 0.6 cm Length) Coupling Body, /" Hose Barb, MPC (Coupling Body, 6. mm Hose Barb, MPC) Polycarbonate 2 Sealing Plug, MPC Polycarbonate DRA306B-N0-B025-0 20 L Basic FlexGro Assembly L 0 L 8

Expanded Basic 20 L FlexGro Biocontainer TepoFlex Acrylic/ 3 3/6" x 3/8" Tubing, 2" Length (.8 mm x 9.5 mm Tubing, 5. cm Length) Platinum- Cured 5 5 Slide Clamp, Medium HDPE 3 6 Male Luer Cap Polycarbonate 7 Swabable Valve / Needleless Injection Site Polycarbonate/ 8 /" Hose Barb x Female Luer Adapter 9 /" x /8" Hose Barb Reduction Fitting (6. mm x 3.2 mm Hose Barb Reduction Fitting) 0 Ratchet Pinch Clamp, Small /8" x /" Tubing, 0" Length (3.2 mm x 6. mm Tubing, 0.6 cm Length) 2 /8" Hose Barb x Female Luer Adapter (3.2 mm HB x Female Luer Adapter) 3 Male Luer Plug Protective Cover, Small Vinyl 5 Ratchet Pinch Clamp, Medium 6 /" x 7/6" Tubing, 0" Length (6. mm x. mm Tubing, 0.6 cm Length) 7 Coupling Body, /" Hose Barb, MPC (Coupling Body, 6. mm Hose Barb, MPC) Polycarbonate 8 Sealing Plug, MPC Polycarbonate DRA5306B-N07-B025-0 20 L Expanded Basic FlexGro Assembly L 0 L 9

Standard 20 L FlexGro Biocontainer TepoFlex Acrylic/ 3 3/6" x 3/8" Tubing, 2" Length (.8 mm x 9.5 mm Tubing, 5. cm Length) Platinum- Cured 6 5 Slide Clamp, Medium HDPE 6 Protective Cover, Small Vinyl 2 7 Male Luer Plug Polypropylene 2 8 /" Hose Barb x Female Luer Adapter Polypropylene 2 9 Male Luer Cap Polycarbonate 0 Swabable Valve / Needleless Injection Site Polycarbonate/ /" x /8" Hose Barb Reduction Fitting (6. mm x 3.2 mm Hose Barb Reduction Fitting) 2 Ratchet Pinch Clamp, Small 3 /8" x /" Tubing, 0" Length (3.2 mm x 6. mm Tubing, 0.6 cm Length) /8" Hose Barb x Female Luer Adapter (3.2 mm Hose Barb x Female Luer Adapter) 5 Ratchet Pinch Clamp, Medium 6 /" x 7/6" Tubing, 0" Length (6. mm x. mm Tubing, 0.6 cm Length) 7 Coupling Body, /" Hose Barb, MPC (Coupling Body, 6. mm Hose Barb, MPC) Polycarbonate 8 Sealing Plug, MPC Polycarbonate DRA6306B-N02-B025-0 20 L Standard FlexGro Assembly L 0 L 0

Basic 22 L FlexGro Biocontainer TepoFlex High Flow Check Valve, 9.5 mm Hose Barb Acrylic/ 3 3/6" x 3/8" Tubing, 2" Length (.8 mm x 9.5 mm Tubing, 5. cm) Length Platinum-Cured 5 Slide Clamp, Medium HDPE 3 6 Male Luer Cap Polycarbonate 7 Swabable Valve / Needleless Injection Site Polycarbonate/ 8 /" Hose Barb x Female Luer Adapter 9 Ratchet Pinch Clamp, Medium 0 /" x 7/6" Tubing, 0" Length (6. mm x. mm Tubing, 0.6 cm) Length Coupling Body, /" Hose Barb, MPC Coupling Body, 6. mm Hose Barb, MPC Polycarbonate 2 Sealing Plug, MPC Polycarbonate DRA306B-N0-B025-0 22 L Basic FlexGro Assembly L 0 L

Expanded Basic 20 L FlexGro Biocontainer TepoFlex Acrylic/ 3 3/6" x 3/8" Tubing, 2" Length (.8 mm x 9.5 mm Tubing, 5. cm Length) Platinum-Cured 5 5 Slide Clamp, Medium HDPE 3 6 Male Luer Cap Polycarbonate 7 Swabable Valve / Needleless Injection Site Polycarbonate/ 8 /" Hose Barb x Female Luer Adapter 9 /" x /8" Hose Barb Reduction Fitting (6. mm x 3.2 mm Hose Barb Reduction Fitting) 0 Ratchet Pinch Clamp, Small /8" x /" Tubing, 0" Length (3.2 mm x 6. mm Tubing, 0.6 cm Length) 2 /8" Hose Barb x Female Luer Adapter (3.2 mm Hose Barb x Female Luer Adapter) 3 Male Luer Plug Protective Cover, Small Vinyl 5 Ratchet Pinch Clamp, Medium 6 /" x 7/6" Tubing, 0" Length (6. mm x. mm Tubing, 0.6 cm Length) 7 Coupling Body, /" Hose Barb, MPC (Coupling Body, 6. mm Hose Barb, MPC) Polycarbonate 8 Sealing Plug, MPC Polycarbonate DRA5306B-N08-B025-0 22 L Expanded Basic FlexGro Assembly L 0 L 2

Standard 22 L FlexGro Biocontainer TepoFlex Acrylic/ 3 3/6" x 3/8" Tubing, 2" Length (.8 mm x 9.5 mm Tubing, 5. cm Length) Platinum-Cured 6 5 Slide Clamp, Medium HDPE 6 Protective Cover, Small Vinyl 2 7 Male Luer Plug Polypropylene 2 8 /" Hose Barb x Female Luer Adapter Polypropylene 2 9 Male Luer Cap Polycarbonate 0 Swabable Valve / Needleless Injection Site Polycarbonate/ /" x /8" Hose Barb Reduction Fitting (6. mm x 3.2 mm Hose Barb Reduction Fitting) 2 Ratchet Pinch Clamp, Small 3 /8" x /" Tubing, 0" Length (3.2 mm x 6. mm Tubing, 0.6 cm Length) /8" Hose Barb x Female Luer Adapter (3.2 mm Hose Barb x Female Luer Adapter) 5 Ratchet Pinch Clamp, Medium 6 /" x 7/6" Tubing, 0" Length (6. mm x. mm Tubing, 0.6 cm Length) 7 Coupling Body, /" Hose Barb, MPC Coupling Body, 6. mm Hose Barb, MPC Polycarbonate 8 Sealing Plug, MPC Polycarbonate DRA6306B-N05-B025-0 22 L Standard FlexGro Assembly L 0 L 3

Basic 50 L FlexGro Biocontainer TepoFlex Acrylic/ 3 3/6" x 3/8" Tubing, 2" Length (.8 mm x 9.5 mm Tubing, 5. cm Length) Platinum-Cured 5 Slide Clamp, Medium HDPE 3 6 Male Luer Cap Polycarbonate 7 Swabable Valve / Needleless Injection Site Polycarbonate/ 8 /" Hose Barb x Female Luer Adapter 9 Ratchet Pinch Clamp, Medium 0 /" x 7/6" Tubing, 0" Length (6. mm x. mm Tubing, 0.6 cm Length) Coupling Body, /" Hose Barb, MPC (Coupling Body, 6. mm Hose Barb, MPC) Polycarbonate 2 Sealing Plug, MPC Polycarbonate DRA307B-N0-B025-0 50 L Basic FlexGro Assembly 5 L 25 L

Expanded Basic 50 L FlexGro Biocontainer TepoFlex Acrylic/ 3 3/6" x 3/8" Tubing, 2" Length (.8 mm x 9.5 mm Tubing, 5. cm Length) Platinum- Cured 5 5 Slide Clamp, Medium HDPE 3 6 Male Luer Cap Polycarbonate 7 Swabable Valve / Needleless Injection Site Polycarbonate/ 8 /" Hose Barb x Female Luer Adapter 9 /" x /8" Hose Barb Reduction Fitting (6. mm x 3.2 mm Hose Barb Reduction Fitting) 0 Ratchet Pinch Clamp, Small /8" x /" Tubing, 0" Length (3.2 mm x 6. mm Tubing, 0.6 cm Length) 2 /8" Hose Barb x Female Luer Adapter (3.2 mm Hose Barb x Female Luer Adapter) 3 Male Luer Plug Protective Cover, Small Vinyl 5 Ratchet Pinch Clamp, Medium 6 /" x 7/6" Tubing, 0" Length (6. mm x. mm Tubing, 0.6 cm Length) 7 Coupling Body, /" Hose Barb, MPC (Coupling Body, 6. mm Hose Barb, MPC) Polycarbonate 8 Sealing Plug, MPC Polycarbonate DRA5307B-N0-B025-0 50 L Expanded Basic FlexGro Assembly 5 L 25 L 5

Standard 50 L FlexGro Biocontainer TepoFlex Acrylic/ 3 3/6" x 3/8" Tubing, 2" Length (.8 mm x 9.5 mm Tubing, 5. cm Length) Platinum-Cured 6 5 Slide Clamp, Medium HDPE 6 Protective Cover, Small Vinyl 2 7 Male Luer Plug Polypropylene 2 8 /" Hose Barb x Female Luer Adapter Polypropylene 2 9 Male Luer Cap Polycarbonate 0 Swabable Valve / Needleless Injection Site Polycarbonate/ /" x /8" Hose Barb Reduction Fitting (6. mm x 3.2 mm Hose Barb Reduction Fitting) 2 Ratchet Pinch Clamp, Small 3 /8" x /" Tubing, 0" Length (3.2 mm x 6. mm Tubing, 0.6 cm Length /8" Hose Barb x Female Luer Adapter (3.2 mm Hose Barb x Female Luer Adapter) 5 Ratchet Pinch Clamp, Medium 6 /" x 7/6" Tubing, 0" Length (6. mm x. mm Tubing, 0.6 cm Length) 7 Coupling Body, /" Hose Barb, MPC Coupling Body, 6. mm Hose Barb, MPC Polycarbonate 8 Sealing Plug, MPC Polycarbonate DRA6307B-N02-B025-0 50 L Standard FlexGro Assembly 5 L 25 L 6

FlexGro, FlexFill, TepoFlex and One-Touch are registered trademarks of Meissner Filtration Products, Inc. Pallflex is a registered trademark of Pall Corporation. 205 Meissner Filtration Products, Inc. All Rights Reserved. FG.0 00 Flynn Road Camarillo, CA 9302 USA +.805.388.99 +.805.388.598 Fax www.meissner.com