TURNOVER 26,505 41,613. Cost of sales (8,585) (13,479) Gross profit 17,920 28,134

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Income statement Year ended 31 December 2013 TURNOVER 26,505 41,613 Cost of sales (8,585) (13,479) Gross profit 17,920 28,134 Selling, general and administration (8,480) (13,314) Research and development (3,923) (6,159) Royalty income 387 608 Other operating income 1,124 1,765 OPERATING PROFIT 7,028 11,034 Finance income 61 96 Finance expense (767) (1,204) Profit on disposal of interest in associates and joint ventures 282 443 Share of after tax profits of associates and joint ventures 43 67 PROFIT BEFORE TAXATION 6,647 10,436 Taxation (1,019) (1,600) PROFIT AFTER TAXATION FOR THE YEAR 5,628 8,836 Profit attributable to non-controlling interests 192 301 Profit attributable to shareholders 5,436 8,535 5,628 8,836 EARNINGS PER SHARE 112.5p 176.6 Diluted earnings per share 110.5p 173.5 US dollar amounts shown above are a convenience translation of the sterling amounts. m $m

Income statement Three months ended 31 December 2013 TURNOVER 6,906 11,235 Cost of sales (2,526) (4,088) Gross profit 4,380 7,147 Selling, general and administration (2,200) (3,580) Research and development (1,070) (1,737) Royalty income 98 160 Other operating income 1,233 1,934 OPERATING PROFIT 2,441 3,924 Finance income 17 28 Finance expense (176) (288) Profit on disposal of interest in associates and joint ventures 253 398 Share of after tax profits of associates and joint ventures 11 17 PROFIT BEFORE TAXATION 2,546 4,079 Taxation (41) (84) PROFIT AFTER TAXATION FOR THE PERIOD 2,505 3,995 Profit attributable to non-controlling interests 44 71 Profit attributable to shareholders 2,461 3,924 2,505 3,995 EARNINGS PER SHARE 51.3p 83.6 Diluted earnings per share 50.4p 82.2 US dollar amounts shown above are a convenience translation of the sterling amounts. m $m

Turnover Pharmaceuticals Year ended 31 December 2013 USA Europe EMAP ROW USA Europe EMAP ROW m m m m $m $m $m $m Respiratory 7,516 3,655 1,907 877 1,077 11,800 5,738 2,994 1,377 1,691 Avamys/Veramyst 249 42 69 71 67 391 66 108 112 105 Flixonase/Flonase 110 7 31 49 23 173 11 49 77 36 Flixotide/Flovent 796 482 117 58 139 1,250 757 184 91 218 Seretide/Advair 5,274 2,769 1,458 429 618 8,280 4,347 2,289 674 970 Serevent 129 51 55 4 19 203 80 87 6 30 Ventolin 642 291 127 171 53 1,008 457 199 269 83 Xyzal 137 - - 18 119 215 - - 28 187 Zyrtec 76 - - 41 35 119 - - 64 55 Anti-virals 667 57 66 293 251 1,047 89 104 460 394 Hepsera 96 - - 70 26 151 - - 110 41 Valtrex 224 45 29 40 110 352 71 45 63 173 Zovirax 81 1 19 35 26 127 2 30 55 40 Zeffix 182 13 12 140 17 286 20 19 220 27 Central nervous system 1,483 440 355 341 347 2,328 691 557 535 545 Imigran/Imitrex 188 80 63 7 38 295 125 99 11 60 Lamictal 557 276 110 78 93 874 433 173 122 146 Requip 125 7 52 14 52 196 11 82 22 81 Seroxat/Paxil 285-53 79 153 447-83 124 240 Wellbutrin 97 16 51 30-152 25 80 47 - Cardiovascular and urogenital 2,239 1,244 533 281 181 3,515 1,953 837 441 284 Arixtra 167 50 84 28 5 262 78 132 44 8 Avodart 857 312 273 104 168 1,345 490 428 163 264 Coreg 131 130 - - 1 206 204 - - 2 Fraxiparine 221-138 83-347 - 217 130 - Lovaza 584 581 - - 3 917 912 - - 5 Metabolic 174 4 42 68 60 273 6 66 107 94 Anti-bacterials 1,239 27 393 750 69 1,945 42 617 1,178 108 Augmentin 630 1 203 393 33 989 2 318 617 52 Oncology and emesis 969 380 339 149 101 1,522 597 532 234 159 Arzerra 75 46 27-2 118 72 43-3 Promacta 186 73 55 22 36 292 115 86 34 57 Tyverb/Tykerb 207 55 82 47 23 325 86 129 74 36 Votrient 331 144 130 37 20 520 226 204 58 32 Dermatology 770 140 170 397 63 1,209 220 267 623 99 Bactroban 98 29 24 38 7 154 45 38 60 11 Duac 72 15 29 16 12 113 24 45 25 19 Rare diseases 495 113 129 48 205 777 177 203 75 322 Volibris 147-82 11 54 231-129 17 85 Flolan 103 25 18-60 162 39 29-94 Immuno-inflammation 161 148 8 1 4 253 232 13 2 6 Benlysta 146 134 8 1 3 229 210 12 2 5 Other pharmaceuticals 799 6 175 369 249 1,255 10 275 579 391 Vaccines 3,420 978 1,049 1,124 269 5,369 1,535 1,647 1,765 422 Boostrix 288 183 65 20 20 452 287 102 31 32 Cervarix 172 6 61 92 13 270 9 96 145 20 Fluarix, FluLaval 251 146 35 43 27 394 229 55 68 42 Hepatitis 629 263 198 123 45 988 413 311 193 71 Infanrix, Pediarix 862 271 398 132 61 1,353 425 625 207 96 Rotarix 375 108 59 164 44 589 170 93 257 69 Synflorix 405-48 350 7 636-75 550 11 19,932 7,192 5,166 4,698 2,876 31,293 11,290 8,112 7,376 4,515 ViiV Healthcare (HIV) 1,386 552 526 171 137 2,176 867 826 268 215 Combivir 116 35 39 35 7 182 55 61 55 11 Epivir 43 10 16 11 6 68 16 25 17 10 Epzicom/Kivexa 763 269 328 78 88 1,198 422 515 123 138 Selzentry 143 58 63 6 16 225 91 99 10 25 Trizivir 97 58 32 4 3 152 91 50 6 5 21,318 33,469 Pharmaceutical turnover includes co-promotion income. US dollar amounts shown above are a convenience translation of the sterling amounts.

Turnover Pharmaceuticals Three months ended 31 December 2013 USA Europe EMAP ROW USA Europe EMAP ROW m m m m $m $m $m $m Respiratory 1,982 975 483 238 286 3,223 1,584 787 387 465 Avamys/Veramyst 54 6 16 18 14 89 10 26 30 23 Flixonase/Flonase 25 4 7 10 4 41 6 12 16 7 Flixotide/Flovent 209 124 30 17 38 340 202 49 28 61 Seretide/Advair 1,398 741 368 119 170 2,272 1,204 599 193 276 Serevent 31 13 14 1 3 51 21 24 1 5 Ventolin 175 80 33 47 15 284 130 53 77 24 Xyzal 36 - - 5 31 58 - - 8 50 Zyrtec 20 - - 11 9 32 - - 17 15 Anti-virals 202 17 16 71 98 326 27 26 116 157 Hepsera 23 - - 15 8 38 - - 25 13 Valtrex 59 15 7 10 27 96 25 11 16 44 Zovirax 20-4 10 6 32-7 16 9 Zeffix 43 3 3 33 4 71 5 5 54 7 Central nervous system 384 116 86 90 92 625 189 140 146 150 Imigran/Imitrex 46 18 15 2 11 75 29 25 3 18 Lamictal 152 77 28 20 27 246 124 46 32 44 Requip 29 1 11 3 14 47 2 18 5 22 Seroxat/Paxil 69-12 19 38 112-19 31 62 Wellbutrin 26 6 14 8 (2) 42 9 23 13 (3) Cardiovascular and urogenital 548 296 135 67 50 894 484 220 109 81 Arixtra 33 7 20 6-54 11 33 10 - Avodart 226 80 72 27 47 367 130 117 44 76 Coreg 29 29 - - - 48 48 - - - Fraxiparine 55-34 21-90 - 56 34 - Lovaza 140 139 - - 1 229 227 - - 2 Metabolic 43 2 12 16 13 70 3 20 26 21 Anti-bacterials 309 6 102 184 17 503 9 166 301 27 Augmentin 165 1 53 101 10 268 2 86 164 16 Oncology and emesis 266 102 89 46 29 432 166 145 74 47 Arzerra 19 13 5-1 31 21 9-1 Promacta 52 19 16 6 11 84 31 26 9 18 Tyverb/Tykerb 49 11 19 14 5 80 18 31 23 8 Votrient 90 39 35 11 5 146 63 57 17 9 Dermatology 171 21 42 93 15 281 35 69 152 25 Bactroban 23 7 6 7 3 38 11 10 12 5 Duac 19 4 8 4 3 31 7 13 6 5 Rare diseases 130 27 34 14 55 211 44 56 22 89 Volibris 40-21 3 16 65-34 5 26 Flolan 23 6 4-13 38 10 7-21 Immuno-inflammation 46 41 2-3 75 67 4-4 Benlysta 37 33 2-2 60 54 3-3 Other pharmaceuticals 255 4 54 98 99 412 7 87 159 159 Vaccines 967 243 275 389 60 1,567 396 447 626 98 Boostrix 91 65 15 7 4 147 104 25 11 7 Cervarix 45 1 19 25-73 1 31 41 - Fluarix, FluLaval 87 36 21 22 8 140 59 33 35 13 Hepatitis 152 55 52 34 11 249 91 85 55 18 Infanrix, Pediarix 208 61 101 32 14 339 99 165 52 23 Rotarix 100 24 15 46 15 163 40 25 74 24 Synflorix 161-12 147 2 258-19 236 3 5,303 1,850 1,330 1,306 817 8,619 3,011 2,167 2,118 1,323 ViiV Healthcare (HIV) 385 171 135 41 38 624 276 220 66 62 Combivir 31 11 7 11 2 50 18 11 18 3 Epivir 9 3 4 2-15 5 6 3 1 Epzicom/Kivexa 211 80 88 18 25 342 129 143 30 40 Selzentry 37 14 17 1 5 61 23 28 2 8 Trizivir 26 16 7 1 2 42 26 11 1 4 5,688 9,243 Pharmaceutical turnover includes co-promotion income. US dollar amounts shown above are a convenience translation of the sterling amounts.

Consumer Healthcare Year ended 31 December 2013 wellness 1,935 3,038 Oral care 1,884 2,958 Nutrition 1,096 1,721 Skin health 272 427 5,187 8,144 USA 951 1,493 Europe 1,819 2,856 Rest of World 2,417 3,795 5,187 8,144 Consumer Healthcare Three months ended 31 December 2013 wellness 469 766 Oral care 447 731 Nutrition 235 386 Skin health 67 109 1,218 1,992 USA 242 394 Europe 435 711 Rest of World 541 887 1,218 1,992

Balance sheet 31 December 2013 m 31 December 2013 $m ASSETS Non-current assets Property, plant and equipment 8,872 14,728 Goodwill 4,205 6,980 Other intangible assets 9,283 15,410 Investments in associates and joint ventures 323 536 Other investments 1,202 1,995 Deferred tax assets 2,084 3,459 Derivative financial instruments 1 2 Other non-current assets 889 1,476 non-current assets 26,859 44,586 Current assets Inventories 3,900 6,474 Current tax recoverable 129 214 Trade and other receivables 5,442 9,034 Derivative financial instruments 155 257 Liquid investments 66 110 Cash and cash equivalents 5,534 9,186 Assets held for sale 1 2 current assets 15,227 25,277 TOTAL ASSETS 42,086 69,863 LIABILITIES Current liabilities Short-term borrowings (2,789) (4,630) Trade and other payables (8,317) (13,806) Derivative financial instruments (127) (211) Current tax payable (1,452) (2,410) Short-term provisions (992) (1,647) current liabilities (13,677) (22,704) Non-current liabilities Long-term borrowings (15,456) (25,657) Deferred tax liabilities (693) (1,150) Pensions and other post-employment benefits (2,189) (3,634) Other provisions (552) (916) Derivative financial instruments (3) (5) Other non-current liabilities (1,704) (2,829) non-current liabilities (20,597) (34,191) TOTAL LIABILITIES (34,274) (56,895) NET ASSETS 7,812 12,968 EQUITY Share capital 1,336 2,218 Share premium account 2,595 4,308 Retained earnings 913 1,515 Other reserves 2,153 3,574 Shareholders equity 6,997 11,615 Non-controlling interests 815 1,353 TOTAL EQUITY 7,812 12,968 US dollar amounts shown above are a convenience transaction of the sterling amounts.