Paramount Chemical Guide

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Paramount Chemical Guide Use this table to evaluate additional chemicals that you may decide to use after the Paramount has been set up for its intended application. Following the table is a chart key and explanation of how to determine if additional and/or alternative chemical applications are appropriate for use in the Paramount Filtered Enclosure.

CHEMICAL NIOSH TWA Odor Thrsh. Estimated Filter Life in Hours at Inlet Concentration 1 PPM 5 PPM 10 PPM 25 PPM 50 PPM PPM = ml/min x 1,1,1,2 Tetrachloro- 2,2 difluoroethane 500 1530 390 236 100 52 25 1,3 1,1,2 Trichloro- 1,2,2 Tri-fluoroethane 1000 200 1318 379 213 98 54 26 1,2 1,2,3 Trimethylbenzene 25 2700 530 270 140 57 23 3 1,2,4 Trimethylbenzene 25 2330 520 265 140 60 23 2,3 1,3 Butadiene 1000 0.45 160 70 54 30 16 38 1,2 1,3,5 Trimethylbenzene 25 2.4 2400 525 265 135 60 22 3 1,2-Dichloro-ethylene 200 17 255 120 85 46 31 41 1,2 2-Butanone 200 30 685 240 155 77 47 35 1,2 2-Butoxyethanol 5 0.1 2100 500 260 105 55 24 2,3 2-Diethylaminoethanol 10 0.011 2090 485 300 125 65 24 2,3 2-Hexanone 50 0.085 1898 451 306 140 77 25 3 2-Pentanone 150 7.7 1325 360 201 91 54 29 1,3 5-Methyl-3-heptanone 25 6 3052 736 385 163 84 20 3 a-methyl styrene 50 0.3 2295 545 280 120 60 24 3 Acetic acid 10 0.15 300 190 151 50 26 55 2,3 Acetic anhydride 5 0.014 1835 510 295 125 65 33 2,3 Acetone 250 653 200 95 70 43 30 43 1,2 Acrylic acid 2 0.092 285 47 26 13 6 46 2,3 Butyl acrylate 10 0.1 2378 627 338 147 78 22 2,3 Carbon disulfide 1 0.42 108 50 35 21 14 52 2,3 Chlorobenzene 75 1.3 1570 437 245 115 63 31 2,3 Chlorobromomethane 200 400 150 85 61 42 30 47 1,2 Crotonaldehyde 2 0.2 920 339 210 109 65 39 3 Cumene 50 0.132 2380 633 342 149 79 22 2,3 Cyclohexanol 50 0.16 1885 685 353 145 74 30 2,3 Cyclohexanone 25 3.5 3000 505 280 125 67 30 2,3 Cyclohexene 300 0.018 930 285 170 82 46 31 1,2 Cyclohexylamine 10 2.6 1980 520 400 130 55 27 2,3 Cyclopentadiene 75 1.8 383 140 87 46 28 38 3 Cyclopentane 600 620 210 148 72 42 33 1,3 Diacetone alcohol 50 0.27 2235 515 275 115 60 25 2,3 Diethylene triamine 1 4394 1066 558 237 124 29 3 Diethyl ketone 200 1126 370 219 107 62 29 1,3 Difluorodibromomethane 100 419 145 88 45 27 34 1,3 Diisobutyl ketone 25 0.31 1785 380 199 82 44 18 2,3 Diisopropylamine 5 0.13 1350 325 175 77 43 22 2,3 Dipropyl ketone 50 2427 646 348 153 81 22 3 Ethyl acetate 400 18 860 270 160 80 52 32 1,2 Ethyl benzene 100 0.6 1760 440 236 102 55 26 1,2 Ethyl bromide 200 3.1 256 105 69 38 24 42 1,2 Ethyl butyl ketone 50 0.35 2150 475 245 102 52 23 3 Ethyl chloride 1000 4.2 64 30 21 12 9 108 1,2 Ethyl ether 400 7 570 185 110 57 32 30 1,3 Ethyl formate 100 20 320 132 161 80 47 39 1,3 Furfural 8 0.636 2310 655 166 86 45 38 2,3 Furfuryl alcohol 10 8 2895 742 460 199 100 36 3 Hexone 50 7.8 1662 488 275 127 70 25 2,3 Isoamyl acetate 100 0.22 1795 410 212 87 47 21 1,2 Isoamyl alcohol (primary) 100 0.072 2100 520 283 122 65 29 1,2 Isoamyl alcohol (secondary) 100 0.072 1520 474 275 131 74 29 1,3 Isobutyl acetate 150 1.1 1590 390 207 91 42 23 1,2 Isobutyl alcohol 50 3.6 1450 430 255 116 66 34 2,3 Isobutyronitrile 8 853 323 202 106 64 34 3 Isophorone 4 0.19 3312 802 417 174 90 21 2,3 Isopropoxyethanol 25 1731 497 276 125 68 27 3 Isopropyl alcohol 400 610 590 237 155 87 52 41 1,2 Detection Method

CHEMICAL NIOSH TWA Odor Thrsh. Estimated Filter Life in Hours at Inlet Concentration 1 PPM 5 PPM 10 PPM 25 PPM 50 PPM PPM = ml/min x Isopropyl ether 500 0.017 1180 295 162 72 40 22 1,2 m-xylene 100 0.62 1800 442 237 102 55 25 1,2 Mesityl oxide 10 0.017 1730 445 242 104 52 27 3 Methyl (n-anyl) ketone 100 0.19 2403 646 348 153 81 22 1,3 Methyl acetate 200 180 310 135 95 50 34 39 1,3 Methyl acrylate 10 0.02 444 155 95 49 29 35 2,3 Methylal 1000 525 175 125 65 40 35 1,3 Methyl cyclohexane 400 1620 405 235 100 55 25 2,3 Methyl isopropyl ketone 200 4.8 1740 500 290 125 65 29 1,3 Methyl methacrylate 100 0.049 1600 410 240 115 60 29 1,2 Methyl isoamyl ketone 50 0.013 2000 465 244 101 52 22 3 Morpholine 20 0.011 1410 440 259 122 57 36 2,3 n-amyl acetate 100 7.3 1840 420 215 92 48 21 1,2 n-butyl acetate 150 0.31 1700 410 220 95 51 24 1,2 n-butyl alcohol 50 11 1815 500 285 132 72 34 2,3 n-butyl lactate 5 7 2818 698 370 159 84 21 3 n-butyronitrile 8 1160 365 203 90 48 37 3 n-pentane 120 1147 560 187 112 56 33 27 2,3 n-propyl acetate 200 0.18 1440 370 205 90 50 26 1,2 n-propyl alcohol 200 41 840 315 200 105 65 42 1,2 Naphthalene 10 0.038 2955 650 330 134 69 28 2,3 o-dichlorobenzene 50 0.7 2340 560 299 125 65 28 2,3 o- Chlorotoluene 50 0.32 2295 560 305 130 85 27 3 o-methylcyclohexanone 400 3118 820 439 191 101 26 2,3 o-sec-butylphenol 5 2050 440 285 90 40 19 3 o-xylene 100 20 1860 456 245 107 56 26 1,2 p-tert-butyltoluene 10 5 1890 400 205 84 44 18 3 p-xylene 100 5.4 1790 437 235 102 55 25 1,2 Phenol 5 0.06 3100 780 480 195 100 35 2,3 Propionitrile 6 410 190 96 42 24 44 2,3 Pyridine 5 1.9 1010 340 172 75 41 39 2,3 sec-amyl acetate 125 0.002 2427 638 341 149 78 21 1,3 sec-butyl acetate 200 7 1687 483 270 123 66 23 1,3 sec-butyl alcohol 100 3.2 1340 400 232 112 62 34 1,2 sec-hexyl acetate 50 0.39 1860 400 205 85 44 19 3 Styrene 50 1.9 150 52 34 19 13 27 2,3 tert-butyl acetate 200 47 1454 425 239 110 61 23 1,3 tert-butyl alcohol 100 957 1090 330 193 91 52 33 1,2 Tetrahydrofuran 200 31 390 160 105 60 37 39 1,2 Toluene 100 1.6 1380 375 212 97 52 30 1,2 Trichloroacetic acid 1 3585 770 385 160 80 31 2,3 Turpentine 100 50 2859 702 365 153 79 20 1,2 Vinyl toluene 100 10 2920 752 395 169 88 24 1,3 Vinylacetate 4 0.12 720 212 120 53 29 34 2,3 Detection Method

Chart Key NIOSH TWA: Recommended time weighted exposure limit as determined by NIOSH for each chemical given in parts per million, based on 10 hours per day, 4 days per week. Odor Threshold: Concentration in PPM that must be reached for odor to be detected. Threshold limits are somewhat subjective due to varying odor sensitivity from person to person. Estimated Filter Life: Estimation of time (in hours) before filter change is required. The table lists 5 different inlet concentrations in PPM. To calculate concentration, see instructions below. PPM = ml/min x: Conversion factors for turning chemical evaporation (ml/min) into inlet concentration. Use the estimated ml/min and multiply by this factor to determine inlet concentration in PPM. Detection Method: Recommended method(s) for monitoring chemical concentrations in the Paramount. The recommendations are given as a number representing primary detection method, followed by a secondary detection method. The number 1 stands for Labconco s Safety-First Vapor Sensor The number 2 represents the use of a chemical detector tube. The number 3 refers to the use of an analytical instrument. Steps for Calculating PPM 1) Determine the amount of the proposed chemical lost to evaporation over a given amount of time. For example, if you use Toluene and lose approximately 500 ml per week during 2 hours of use per day. 2) Convert the amount lost into ml/min. For this example: 500 ml week 1 week 10 hours use 10 hours 600 minutes 500 ml lost 600 minutes X X = =.83 ml/min 3) Convert ml/min to PPM by multiplying ml/min by the conversion factor found in the second to the last column on the right. For Toluene, this would be.83 x 30 = 24.9 PPM. 4) Find the PPM value on the chart that comes closest to the value you just calculated in step #3. In this example, 25 PPM is close to the calculated 24.9. We may approximate the filter life to be around 100 hours of actual use. 5) Insert the estimated filter life into the estimated usage to determine how long filters will last. 100 hours filter life 10 hours per week use = 10 weeks before filter saturation 3-01-7/00-A-400-R3