AS , EN12469 (Microbiological Testing Method)

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AS 1386.5, EN12469 (Microbiological Testing Method)

Main Features Esco antimicrobial surface on all painted surfaces. Sentinel Microprocessor controller supervises all functions. Sterile work zone environment created for optimum product protection. Long-life ULPA filter for supply airflow. Spillage-retention work surface with recessed central area. (Not applicable for Model ES1604) Available in 0.9, 1.2, 1.5 and 1.8 meter models (3', 4', 5' and 6') g g supplier of laminar flow clean benches to the life sciences and laboratory markets. Horizontal and Vertical Laminar Flow Clean Benches Esco Labculture Laminar Flow Clean Benches are available in both horizontal and vertical flow models. In both models, air is taken in from above the cabinet and passed through a ULPA filter. In horizontal flow models filtered air is then passed laminar (unidirectional) air stream before being exhausted through the front opening of the cabinet. In horizontal flow cabinets (Model ES17 there is a slightly reduced level of turbulence compared to vertical flow cabinets (Model ES16) due to the airflow not striking th work surface. However vertical flow cabinets generate less turbulence around large pieces of equipment as compared to horizontal flow cabinets. Labculture Vertical Laminar Flow Clean Bench Laminar Flow Clean Benches, Horizontal and Vertical

Touchpad data entry buttons permit control settings and access to diagnostics, default settings and hierarchical hical menus. Color coded d indicator lamps display green for primary function (fan operation); blue for secondary function (fluorescent e lights and electrical ca outlet); and orange for Programmable automatic UV light timer simplifies operation, enhances contamination control, extends UV lamp life and saves energy. A graphical interface indicates cabinet performance. Digital read-out with alpha-numeric display indicates all input, status and alarm functions. All functions can be user activated through touch-pad programming access; see Operations Manual. When programmed ON, an airflow alarm warns of deviations from normal velocities. Applications Uses include applications where there is no generation of biohazardous materials and operator protection is not required. protocols pharmaceutical, aerospace, and medical devices industries Designed for Enhanced Usability Esco Laminar Flow Clean Benches incorporate a number of features to ensure operator comfort and enhanced productivity. stainless steel, making the work zone not chip, rust or generate particles. with a recessed central area ensures that all liquid spills are contained. with a curved front edge is designed for maximum operator comfort. On our horizontal flow models a raised edge at the back of the work zone prevents spills from damaging the filter. ballasted, 5000k lighting provides excellent illumination of the work and instant start. on all models provides protection to the filter and improves airflow uniformity. On the horizontal flow benches, the diffuser provides additional protection in the event of an accidental spillage and is easy to clean. User-Friendly Control System control system supervises all cabinet functions. user requirements and come equipped with a number of enhanced features. technology, measures all critical cabinet airflow parameters allowing superior sensors ensure increased accuracy. with integral RFI and noise filters, are superior to conventional step" controllers and offer infinite adjustment from zero to maximum setting. Esco ULPA Filter Efficiency can be set to restrict access to the main menu. product protection by alerting the user in the event of low airflow. provides continuous monitoring of cabinet airflow. cally adjusts to maintain airflow as the filter becomes loaded with particulates, eliminating the need for constant adjustment and ensuring optimum performance and product protection. Enhanced Filtration System horizontal and vertical flow cabinets is designed to provide the highest level of air quality within the work zone, meeting all relevant standards (see technical specifications for details). Esco cabinets use ULPA filters (per IEST-RP-CC001.3) instead of conventional HEPA filters commonly found in biological safety cabinets. While HEPA filters offer 99.99% typical efficiency at 0.3 micron level, ULPA filters provide >99.999% typical efficiency for particle sizes of 0.1 to 0.3 micron level.

Horizontal Laminar Flow Clean Bench Blower Supply ULPA Filter Horizontal Laminar Flow of Clean Air ULPA-filtered air Room air / Inflow air Room air is taken in from the top of the cabinet through a disposable pre-filter with 85% arrestance, trapping larger particles and prolonging the life of the main filter. Air is forced evenly through an ULPA filter resulting in a stream of clean, horizontal, laminar air within the main chamber with a velocity of 0.475 m/s (95 fpm), flushing all contaminants from the work zone. The purified air travels across the work zone in a horizontal (unidirectional) stream and is exhausted through the entire open front of the cabinet. significantly cleaner than the usual Class 5 classification on cabinets offered by the competition. improved minipleated separation technique to maximize surface area (improving efficiency and extending the life of the filter), operate at a typical micron sizes, providing superior product protection over conventional HEPA filters. all models traps large particles in the inflow air prior to reaching the main filter, protecting it against damage and prolonging its life. slots at the back of the work zone which recirculate air back into the blower plenum, minimizing turbulence, eliminating dead air zones, prolonging main filter life and enhancing protection. Mini-pleat Separatorless Filter (left) vs. Conventional Aluminium Separator Filter (right) Esco cabinets use Swedish Camfil Farr mini-pleat filters without aluminum separators to increase filter efficiency, minimize the chance of leakage, and to prolong filter life. Filters include a lightweight aluminum frame for structural stability and elimination of swelling common to conventional wood frames. The Highest Quality Cabinet Construction All Esco products are manufactured for the most demanding laboratory applications. chemical resistance and enhanced durability for a long service life. steel. Esco Centrifugal Fan with External Rotor Motor (left) vs. ight) co cabinets use German made ebm-papst ermanently lubricated, centrifugal motor/ blowers th external rotor designs. tegrated blades narrow the profile and eliminate eed for a motor shaft. otors are selected for energy efficiency, compact esign, and flat profile. The completely integrated sembly optimizes motor cooling. l rotating parts are unitized and balanced for mooth, quiet, vibration-free operation. compatible. Blower Efficiency incorporate permanently lubricated direct drive centrifugal blowers. design reduces operating costs and has extremely low noise and vibration levels. airflow as the filter becomes loaded, ensuring optimum efficiency and product protection. Designed and Built to Exceed Safety Criteria All components used in Esco products meet or exceed all applicable safety requirements. tested for safety and performance in accordance with international standards. UL recognized, ensuring superior electrical safety for the operator. meet general safety requirements set by independent testing laboratories (see technical specifications for details). contamination and product protection using microbiological testing methods. Laminar Flow Clean Benches, Horizontal and Vertical

ESCO ESCO Horizontal Laminar Flow Clean Bench Technical Specifications (A-Series) 4 11 12 5 6 7 8 9 10 1 2 3 13 14 50 mm (2.0") 1. Airflow sensor 2. Removable filter diffuser 3. ULPA filter 4. Pre-filter 5. Blower 6. Fluorescent lamp 7. IV Bar Retrofit Kit provisions 8. Front cover Retrofit Kit 9. UV light Retrofit Kit provision* 10. Service fixture Retrofit Kit provisions (2 on each side) 11. Esco Sentinel microprocessor control 12. Internal stainless steel side panel 13. Stainless steel work surface with Front curved edge 14. Electrical outlet Retrofit Kit provision (LHC-3: 1 single outlet; LHC-4 and above: 2 single outlets) Vertical Laminar Flow Clean Bench Technical Specifications (A-Series) 11 4 5 6 3 2 12 7 8 9 1 10 13 14 1. Downflow velocity sensor 2. Downflow filter diffuser 3. ULPA filter 4. Pre-filter 5. Blower 6. Fluorescent lamp 7. IV bar Retrofit Kit provision 8. Optional front cover 9. UV lamp Retrofit Kit provision 10. Service fixture Retrofit Kit provision (2 on each side) 11. Esco Sentinel microprocessor control 12. Internal stainless steel panel 13. Stainless steel work surface with curved front edge 14. Electrical outlet Retrofit Kit provision (LVC-3: 1 single outlet, LVC-4 and above: 2 single outlets)

Vertical Laminar Flow Clean Bench Blower Supply ULPA Filter Vertical Laminar Flow of Clean Air Auto-Purge Slots Room air is taken from the top of the cabinet through a disposable pre-filter with 85% arrestance, trapping larger particles and prolonging the life of the main filter. Air is forced evenly through a ULPA filter resulting in a stream of clean, vertical, laminar air within the main chamber with a velocity of 0.475 m/s (95 fpm), flushing all contaminants from the work zone. ULPA-filtered air Room air / Inflow Air The purified air travels across the work zone in a vertical (unidirectional) stream and is exhausted through the entire open front of the cabinet and through Auto- Purge slots in the back wall. The Auto- Purge slots are designed to eliminate air turbulence and dead-air corners in the work zone. In addition, the Auto-Purge Slots prolong the filter life. Warranty All Esco Labculture vertical and horizontal flow clean benches come with an extended parts and accessories. Contact your local representative for specific warranty details. Accessories and Options Esco offers a variety of options and accessories to meet local applications. tative for ordering information. Support Stands Electrical Outlets and Utility Fixtures North America Cabinet Accessories (recommended when UV lamp is used) Cabinet Performance Air Quality Filtration Electrical Safety Standards Compliance Antimicrobial Powder-Coating Bacterial Population (10 folds) 8 6 4 2 All exterior painted surfaces are powder-coated with Esco Isocide, an antimicrobial inhibitor to diminish contamination. Isocide is integrated into the coating substrate and cannot wash out or diminished by repeated cleaning. Performance results are available upon request. Contact Esco or your Esco Sales Representative for details. 0 4 hours 8 hours 12 hours 16 hours 20 hours 24 hours Contact Time in Hours Laminar Flow Clean Benches, Horizontal and Vertical

General Specifications, Labculture Vertical Laminar Flow Clean Benches Note to customer: Insert electrical voltage number into last model number digit _ when ordering. Model ES1601 ES1602 ES1603 ES1604 Nominal Size External Dimensions (W x D x H) Internal Work Area, Dimensions (W x D x H) Laminar Airflow Velocity Pre-Filter ULPA Filter Typical Efficiency Sound Emission Per IEST-RP-CC002.2* <59 dba <59 dba Fluorescent Lamp Intensity At Zero Ambient Main Body Cabinet Construction >900 Lux Coated with Isocide antimicrobial coating Shipping Weight*** Shipping Dimensions, Maximum (W x D x H)*** Shipping Volume, Maximum*** Electrical** Model Voltage Ø Ø Ø Additional voltages may be available; contact Esco for ordering information. ***Cabinet only; excludes optional stand. General Specifications, Labculture Horizontal Laminar Flow Clean Benches Note to customer: Insert electrical voltage number into last model number digit _ when ordering. Model ES1701 ES1702 ES1703 ES1704 Nominal Size External Dimensions (W x D x H) Internal Work Area, Dimensions (W x D x H) Laminar Airflow Velocity Pre-Filter ULPA Filter Typical Efficiency Sound Emission Per IEST-RP-CC002.2* <59.5 dba <59 dba Fluorescent Lamp Intensity At Zero Ambient Cabinet Construction Main Body >2500 Lux Coated with Isocide antimicrobial coating Shipping Weight*** Shipping Dimensions, Maximum (W x D x H)*** Shipping Volume, Maximum*** (95.0 cu.ft) Model Voltage Electrical** Ø Ø Ø **Additional voltages may be available; contact Esco for ordering information. ***Cabinet only; excludes optional stand.

General Specifications, Labculture Horizontal Laminar Flow Clean Benches Model ES1705 ES1706 ES1707 ES1708 Nominal Size External Dimensions (W x D x H) Internal Work Area, Dimensions (W x D x H) Laminar Airflow Velocity Pre-Filter ULPA Filter Typical Efficiency Sound Emission Per IEST-RP-CC002.2* <59.5 dba <59 dba Fluorescent Lamp Intensity At Zero Ambient Cabinet Construction Main Body >2500 Lux Coated with Isocide antimicrobial coating Shipping Weight*** Shipping Dimensions, Maximum (W x D x H)*** Shipping Volume, Maximum*** (95.0 cu.ft) Electrical** Model Voltage Ø Ø Ø **Additional voltages may be available; contact Esco for ordering information. ***Cabinet only; excludes optional stand. General Specifications, Labculture Horizontal Laminar Flow Clean Benches Note to customer: Insert electrical voltage number into last model number digit _ when ordering. Model ES1709 ES1710 ES1711 Nominal Size External Dimensions (W x D x H) Internal Work Area, Dimensions (W x D x H) Laminar Airflow Velocity Pre-Filter ULPA Filter Typical Efficiency Sound Emission Per IEST-RP-CC002.2* <59 dba Fluorescent Lamp Intensity At Zero Ambient Cabinet Construction Main Body >2500 Lux Coated with Isocide antimicrobial coating Shipping Weight*** Shipping Dimensions, Maximum (W x D x H)*** Shipping Volume, Maximum*** Model Voltage Electrical** 1 Ø 2 3 Ø **Additional voltages may be available; contact Esco for ordering information. ***Cabinet only; excludes optional stand. Laminar Flow Clean Benches, Horizontal and Vertical

10 escoglobal.com LIVE SUPPORT PCR Cabinets Esco Global Offices Esco Micro Pte Ltd 9010019_Laminar Flow_LHC_Brochure_A4_vB1_12/11 Esco can accept no responsibility for possible errors in catalogues, brochures and other printed materials. Esco reserves the right to alter its products and specifications without notice. All trademarks and logotypes in this material are the property of Esco and the respective companies.