Class II, Biological Safety Cabinets Probably the Most Advanced Energy-Efficient, Safe, and Ergonomic Biosafety Cabinet in the World

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Class II, Biological Safety Cabinets Probably the Most Advanced Energy-Efficient, Safe, and Ergonomic Biosafety Cabinet in the World esafe Class II, Biosafety Cabinet, Model EC2-4L8.

Airflow Sensor Monitors real-time airflow for safety Alert the user if airflow is insufficient High-end Accusense sensor made by Degree C Sentinel TM Platinum Microprocessor Controller Large graphical LCD to illustrate cabinet operating parameters Displays all safety information on one screen Centered and angled down for easy reach & viewing Unique Stainless Steel and Glass Hybrid Wall (L-Series) Large corner radius for easy cleaning Glass side walls to improve visibility Electrical outlets, service fixtures VHP / HPV ports on the side wall Motorized Window Conveniently move the window by fingertips Window automatically stops at safe operating height 2 Multi-pieces Work Tray (L-Series) Easy to be lifted for cleaning Simple design, without support beams Raised Arm Rest Helps prevent grille blocking Comfortable working posture Horizontal and angled arm placement Angled Drain Pan Easy to clean Available in 1.2, 1.5, and 1.8 meter width Does not harbor contaminants Biological Safety Cabinets EC2 Class II Biological Safety Cabinets

Energy Efficient ECM Motor Powered by latest generation ECM motor, that is more efficient than legacy ECM and VFD motors 70% Energy savings compared to AC motor Stable airflow, despite building voltage fluctuations & filter loading Night Setback mode to further reduce power consumption by 60% High Grade H14 Filter 10x Filtration efficiency of conventional H13 HEPA filter Creates ISO Class 3 work zone instead of industry-standard ISO Class 5 Esco cabinets use high grade H14 filter that offers 99.999% efficiency for particle sizes of 0.1 to 0.3 micron, better than conventional H13 HEPA filters that only offers 99.99 % efficiency at 0.3 micron. Dynamic Chamber Blower plenum and side walls Prevent contaminants from escaping outside 3 Positive pressure Negative pressure Isocide TM Powder Coat Silver-ion impregnated powder coat Inhibit microbial growth to improve safety Certified by TÜV-Nord Germany Biosafety Cabinets Air Quality Filtration Electrical Safety Standards Compliance EN 12469, Europe ISO 14644.1, Class 3, Worldwide JIS B9920, Class 3, Japan JIS BS5295, Class 3, Japan US Fed Std 209E, Class 1 USA EN-1822 (H14), Europe IEST-RP-CC001.3, USA IEST-RP-CC007, USA IEST-RP-CC034.1, USA IEC61010-1, Worldwide EN-61010-1, Europe UL-C-61010-1, USA CAN/ CSA22.2, No.61010-1 The TÜV-Nord certified cabinet models are: EC2-4L8, EC2-4S8, EC2-5L8, EC2-5S8, EC2-6L8, and EC2-6S8

H14-filtered air Unfiltered / potentially contaminated air Room air / Inflow air Cabinet Filtration System Ambient air is pulled through front grille to create inflow, without going into the work surface. Inflow is joined by half of the downflow, to create front air curtain that is fine-tuned to create a large performance envelope. The combined air stream travels through the back air column towards the blower. Approximately 1/3 of the air in the common plenum is exhausted through the ULPA filter to the room. The remaining 2/3 of the air is passed through the downflow ULPA filter and into the work area as a vertical laminar flow air to create ISO Class 3 work surface and prevents cross contamination. Near the work surface, the downflow splits. About Half goes to the front grille, and half goes to the rear grille. A small portion enters the the side capture zones to prevent dead air corners (small blue arrows). The design was optimized to give large performance envelope, that provides operator and product protection at wide Inflow and Downflow variation from the Nominal point. The Performance Envelope Concept Nominal Airflow Personnel / Product Protection Area of Personnel / Product Protection Nominal 0.35, 0.50 m/s No Personnel / Product Protection Area of no Personnel / Product Protection EC2 Biological Safety Cabinet Engineering Drawing 1 10 11 2 3 4 4 12 13 14 15 16 5 6 7 8 9 650 mm (25.6 ) 1450 mm (57.1 ) 18 19 21 22 17 1. Exhaust Collar (Optional) 2. ECM Downflow Blower 3. ECM Exhaust Blower 4. Downflow H14 filter 5. Downflow Sensor by Degree C 6. UV Lamp Provision 7. Bioquell Cable Port 8. Steris VHP / Bioquell HPV Port 630 mm (24.8 ) 1220 mm / 1525mm / 1830 mm 820 mm (32.3) (48.0 ) / (60.0 ) / (72.0 ) 857 mm (33.7) 1340 mm / 1645 mm /1950 mm (52.8 ) / (64.8 ) / (76.8 ) Stainless Steel Side Wall Variant 9. Optional Solenoid Valve (mandatory for gas valve) 10. Exhaust H14 Filter 11. Electrical / Electronics Panel 12. T5 Fluorescent Lamps 13. IV Bar Retrofit Kit Provision 14. Standard Electrical Outlet Retrofit (2 on each side) 15. Side Tempered Glass (L-Series). SS & EG double walls (S-Series) 16. Service Fixture Retrofit Kit Provision (2 on each side) 17. Stainless Steel Dual Posture Arm Rest 18. Sentinel TM Platinum Microprocessor Control System 19. Laminated Glass Motorized Sliding Sash Window 20. Stainless Steel Work Tray 21. Exhaust Sensor by Degree C 22. Power Inlet and Cable Clip Optional Exhaust Collar Positions for Thimble-Ducting for EC2 Models ø250 mm (ø9.8") 20 165 mm (6.5") 4' 463 mm (18.2") 5' 581 mm (22.9") 6' 705 mm (27.8") 260 mm (10.2") Side View - All Sizes Top View - All Sizes Biological Safety Cabinets EC2 Class II Biological Safety Cabinets

Hybrid Glass and Stainless Steel Side Wall (L-Series) Side glass for visibility and Stainless Steel curved wall for good cleanability. 4x electrical outlets and 4x service fixtures total on side walls, for easy reach. Built-in VHP / HPV port and HPV cable port on right side. Multi-piece trays that are easy to lift for cleaning. Double Layer Stainless Steel & EG Side Wall (S-Series) Negative pressure between two layer side walls improves leak protection. 4x electrical outlets and 4x service fixtures total on side walls, for easy reach. Built-in VHP / HPV port and HPV cable port on right side. Single-piece tray with sump prevents spillage to drain pan and easy to clean. 5 Angled Arm Rest Prevent grille blocking Comfortable Dual posture: horizontal or angled arm placement

EC2 Sentinel TM Platinum Microprocessor Controller Cabinet status summary (safe / unsafe). Fixed touch pad buttons to control primary functions. Color-coded LEDs to indicate activation of primary functions. Multi Language: English, German. Large graphical LCD illustrates the cabinet inflow, downflow, sash opening, and filter life. Also showing the date, time, and airflow & sash status. Variable touchpad buttons to control secondary functions. Grouped menu, set, and arrow buttons for fast menu navigation. Accessories for esafe Biological Safety Cabinets SPC-_A0 gen2 Model Description SPL-_A0 gen2 Leveling Feet Stand, Sitting Posture, Adjustable 28 to 30" (711-762 mm), _ = Size in Feet (4,5,6), Example: SPL-4A0 gen2 for 4 ft, Shipped Flat SPL-_B0 gen2 Leveling Feet Stand, Standing Posture, Adjustable 34 (864-914 mm), _ = Size in Feet (4,5,6), Example: SPL-4B0 gen2 for 4 ft, Shipped Flat SPL-_B0 gen2 SPC-_A0 gen2 Caster Wheel Stand, Sitting Posture, 28" (711 mm) Fixed Height, _ = Size in Feet (4,5,6), Example: SPC-4A0 gen2 for 4 ft, Shipped Flat SPC-_B0 gen2 Caster Wheel Stand, Standing Posture, 34" (864 mm) Fixed Height, _ = Size in Feet (4,5,6), Example: SPC-4B0 gen2 for 4 ft, Shipped Flat STL-_A0 Telescoping Feet Stand, Manually Adjustable 28" to 36" (711-914 mm) by Pins, _ = Size in Feet (4,5,6), Example: STL-4A0 for 4 ft, Shipped Flat STL-_A0 6 SPM-_A1 Hydraulic Stand, Electrically Adjustable 28" to 36" (711-914 mm), _ = Size in Feet (4,5,6), Example: SPM-4A1 for 4 ft, Shipped assembled SF-1G20 Gas Service Fixture Kit, must be ordered with solenoid valve SPM-_A1 SF-1W20 Water Service Fixture Kit SF-1V20 Vacuum Service Fixture Kit IV-XXXX IV bar kit, Includes 6 hooks, Max Load 6 Kg (13 lbs), Specify model when ordering, Field installed. XXXX = Cabinet internal width, minus 10 mm SF-1G20 DAMPER 10 Air Tight Damper for all BSC, 9.8" (250mm) diameter x 9.8 height (250 mm) fits inside 10" (254 mm) duct ECO-EC2-_ Thimble exhaust transition. Specify size when ordering (e.g. ECO-EC2-4) ABBV-10 Anti Blow Back Valve, automatically shuts exhaust, preventing back flow in the duct,10" diameter ECO-EC2-_ TEM-4 Tri-Safe Exhaust Module. 4ft / 1.2 m only. (Comes with extra H14 filter, damper, VHP / HPV port, and Ø250 mm (10 ") exhaust collar) DCN-BAG Plastic decon bag for formalin decon on all BSC FOOT REST Ergonomic Foot Rest, free-standing, angled surface, easily adjustable from 75 to 275 mm increment, 500 mm wide, Black Rubber Matte TEM-4 Comprehensive Performance Testing At Esco Every esafe model manufactured by Esco is individually tested, documented by serial number and validated with the following test methods: Inflow and downflow velocity. PAO aerosol challenge for filter integrity. Airflow pattern visualization. Electrical safety to IEC61010-1. Additional KI-Discus containment and microbiological testing are performed on statistical sampling basis. Biological Safety Cabinets EC2 Class II Biological Safety Cabinets

TECHNICAL SPECIFICATIONS Glass Side : 230 V, 50 / 60 Hz EC2-4L8 EC2-5L8 EC2-6L8 Stainless Steel Side: 230 V, 50 / 60 Hz EC2-4S8 EC2-5S8 EC2-6S8 Nominal Size 4ft / 1.2 m 5ft / 1.5 m 6ft / 1.8 m Width 1340 mm (52 ¾") 1645 mm (64 ¾") 1950 mm (76 ¾") External Dimensions (W x D x H) Depth without arm rest and front sash cover removed 790 mm (30 ") Depth with arm rest 857 mm (33 4 5 ") Height 1450 mm (57") Gross Internal Dimensions (W x D x H) Width 1220 mm (48") 1525 mm (60") 1830 mm (72") Depth 630 mm (22 ¾") Height 650 mm (25 ½") Usable Work Area 0.63 m 2 (6.8 ft 2 ) 0.79 m 2 (8.5 ft 2 ) 0.95 m 2 (10.2 ft 2 ) Tested Opening 175 mm (7") Working Opening Average Airflow Velocity Inflow Downflow 190 mm (7 ½") 0.50 m/s (100 fpm) 0.35 m/s (70 fpm) Inflow 385 m 3 / h (227 cfm) 482 m 3 / h (284 cfm) 518 m 3 / h (305 cfm) Airflow Volume Downflow 892 m 3 / h (525 cfm) 1118 m 3 / h (658 cfm) 1339 m 3 / h (788 cfm) Exhaust 385 m 3 / h (227 cfm) 482 m 3 / h (284 cfm) 518 m 3 / h (305 cfm) Required Exhaust Volume With Optional Thimble Exhaust Collar Required Static Pressure For Optional Thimble Exhaust Collar 538 m 3 / h (317 cfm) 615 m 3 / h (362 cfm) 823 m 3 / h (485 cfm) 31 Pa / 0.12 in H 2 O 35 Pa / 0.14 in H 2 O 47 Pa / 0.18 in H 2 O 7 HEPA Filter Typical Efficiency >99.999% at 0.1 to 0.3 micron as per IEST-RP-CC001.3 USA (ULPA) >99.999% at MPPS as per EN 1822 EU (H-14) Sound Emission* NSF / ANSI 49 56 59 59 EN 12469 53 56 56 Fluorescent Lamp Intensity (lux) Main body 1340 lux (124 ft-cd) max (adjustable) 1610 lux (150 ft-cd) max (adjustable) 1457 lux (135 ft-cd) max (adjustable) 1.5 mm (0.06") 18 gauge electro-galvanized steel with white oven-baked epoxy-polyester Isocide TM antimicrobial powder-coated finish Cabinet Construction Work Zone Side Walls (L-Series) Side Walls (S-Series) 1.5 mm (0.06") 16 gauge stainless steel, type 304, with 4B finish UV absorbing tempered glass, 6 mm (0.2"), colorless and transparent 1.5 mm (0.06") 16 gauge stainless steel, type 304, with 4B finish 1.5 mm (0.06") 16 gauge stainless steel, type 304, with 4B finish Electrical Cabinet Full Load Amps (FLA) 10.5 11.1 11.3 Heat Generation (BTU / Hr)** 751 887 1228 Nominal Power Consumption 220 W 315 W 360 W Net Weight *** 259 Kg (571 lbs) 303 Kg (668 lbs) 350 Kg (772 lbs) Shipping Weight *** 289 Kg (637 lbs) 343 Kg (756 lbs) 400 Kg (882 lbs) Shipping Dimensions, Maximum (W x D x H) *** 1520 mm x 920 mm x 1750 mm (59" x 37" x 69") 1710 mm x 920mm x 1750 mm (67" x 37" x 69") 2120 mm x 920 mm x 1750 mm (83" x 37" x 69") Shipping Volume, Maximum *** 2.4 m 3 (85 ft 3 ) 2.7 m 3 (95 ft 3 ) 3.4 m 3 (120 ft 3 ) * Noise reading in open field condition / anechoic chamber. Noise reading in normal room varies by room size, layout, and background noise, but may reach roughly 3-4 dba above these values. ** Cabinet Heat Load (BTU/Hr) = Cabinet nominal power x 3.412 *** Cabinet only, excludes optional stand.

ESCO Global Network 8 ART Equipment Biological Safety Cabinets CO 2 Incubators Compounding Pharmacy Equipment Containment / Pharma Products Ductless Fume Hoods Freeze Dryer Lab Animal Research Products Laboratory Fume Hoods Laboratory Ovens and Incubators Laminar Flow Clean Benches PCR Cabinets PCR Thermal Cyclers Powder Weighing Balance Enclosures Ultra-low Freezers The Esco Group of Companies is a global life sciences tools provider with sales in over 100 countries. The group is active in lab equipment, pharma equipment and medical devices. Manufacturing facilities are located in Asia and Europe. R&D is conducted worldwide spanning the US, Europe and Asia. Sales, service and marketing subsidiaries are located in 12 major markets including the US, UK, Singapore, Japan, China and India. Regional distribution centers are located in the US, UK, and Singapore. escoglobal.com LIVE SUPPORT Life Science Chemical Research Assisted Reproductive Technology (ART) Pharmaceutical Equipment General Equipment Esco Technologies, Inc. 2940 Turnpike Drive, Units 15-16 Hatboro, PA 19040, USA Toll-Free USA and Canada 877-479-3726 Tel 215-441-9661 Fax 215-441-9660 us.escoglobal.com usa@escoglobal.com Esco Micro Pte. Ltd. 21 Changi South Street 1 Singapore 486 777 Tel +65 6542 0833 Fax +65 6542 6920 mail@escoglobal.com www.escoglobal.com Esco Global Offices Manama, Bahrain Beijing, China Chengdu, China Guangzhou, China Shanghai, China Bangalore, India Delhi, India Mumbai, India Jakarta, Indonesia Osaka, Japan Kuala Lumpur, Malaysia Melaka, Malaysia Manila, Philippines Singapore Seoul, South Korea Salisbury, UK Philadelphia, PA, USA Hanoi, Vietnam Esco Micro Pte Ltd Cert. No: 651076 9010188_Biological Safety Cabinet_EC2_brochure_A4_Sept-2013 Esco can accept no responsibility for possible errors in catalogues, brochures and other printed materials. Esco reserves the right to alter its products and specifications without notice. All trademarks and logotypes in this material are the property of Esco and the respective companies. PT Esco Bintan Indonesia Cert. No: 651333/E