Product Stewardship Summary 2-Ethylhexyl acrylate General Statement 2-Ethylhexyl acrylate is a building block in the production of polymer coatings, sealants, and adhesives that improves the water and sun resistance of the final product. 2-Ethylhexyl acrylate is a moderate hazard material and risk of adverse health effects associated with both occupational and consumer use of this chemical is anticipated to be moderate. Chemical Identity Name: 2-Ethylhexyl acrylate Brand Names: Not Applicable Chemical name (IUPAC): 2-ethylhexyl prop-2-enoate CAS number(s): 103-11-7 EC number: 203-080-7 Molecular formula: C11H20O2 Structure: Uses and Applications 2-Ethylhexyl acrylate is used in the production of homopolymers, co-polymers, and pressure sensitive adhesives. 2- Ethylhexyl acrylate is also used in paint additives and plasticizers. Registered trademark, Ashland or its subsidiaries, registered in various countries TM Trademark, Ashland or its subsidiaries, registered in various countries * Trademark owned by a third party 2016, Ashland
Physical/Chemical Properties Phys/Chem Safety Assessment Property Form Substance Physical state Liquid Color Colorless Odor Pleasant/Sweet Density 0.88 g/cm 3 @ 20 C Value Melting / boiling point -90 / 215 C Flammability Not flammable Explosive properties Not explosive Self-ignition temperature 245 C at 1013 hpa Vapor pressure 0.24 hpa @ 25 C Mol weight 184.28 g/mol Water solubility 9.6 mg/l @ 25 C Flash point 86 C Octanol-water partition coefficient (Logkow) 4.64 @25 C Exposure, Hazard and Safety Assessment The following section describes possible exposures scenarios and hazards associated with 2-ethylhexyl acrylate. The exposure assessment describes both the amount of and the frequency with which a chemical substance reaches a person, a population of people, or the environment. Hazard refers to the inherent properties of a substance that make it capable of causing harm to human health or the environment. The safety assessment reports the possibility of a harmful event arising from exposure to a chemical or physical agent under specific conditions. Just because a substance may possess potentially harmful properties does not mean that it automatically poses a risk. It is not possible to make that determination without understanding the exposure. Human Health Effects Human Exposure Assessment Consumer: 2-Ethylhexyl acrylate is used in the production of polymer coatings and finishes, adhesives, sealants, and plastics. It is not anticipated to be present as an ingredient in consumer products. Consumer exposure is most likely limited to extremely low levels of residual monomer that may be present within polymers used in consumer products. Worker: In industrial settings, 2-ethylhexyl acrylate is manufactured and handled in closed processes as much as possible, which ensures that worker exposure to 2-ethylhexyl acrylate is minimized. The proper use of personal protective equipment during loading, unloading, sampling or during maintenance operations, will further minimize potential exposures to 2-ethylhexyl acrylate. Human Hazard Assessment: 2-Ethylhexyl acrylate has low acute and repeat exposure toxicity following both oral and dermal exposures. Skin contact can result in severe irritation and may result in skin sensitization. 2-Ethylhexyl acrylate is associated with slight reversible eye irritation. 2-Ethylhexyl acrylate is neither mutagenic or genotoxic and is not associated with reproductive or developmental toxicity. Dermal exposures to high concentrations in some test animals have caused skin tumors; however, these findings are believed to be secondary to chronic irritation/tissue injury.
Effect Assessment Acute Toxicity Oral / inhalation / dermal Irritation / corrosion Skin / eye / respiratory test Toxicity after repeated exposure Oral / inhalation / dermal Genotoxicity / Mutagenicity Carcinogenicity Reproductive/Developmental Toxicity Result Low acute toxicity Inhalation may cause respiratory irritation Skin contact causes moderate to severe irritation. Eye contact with liquid or vapor could result in slight, temporary eye irritation. May cause an allergic skin reaction. Does not cause significant toxicity to internal organs after repeated exposure in animal studies. The predominant effect is local irritation. Neither mutagenic or genotoxic. 2-Ethylhexyl acrylate is not classifiable as to its carcinogenicity to humans. Dermal exposures to high concentrations in some test animals have caused skin tumors; however, these findings are believed to be secondary to chronic irritation/tissue injury. Does not cause reproductive effects in animal studies. Did not cause developmental effects in animal exposure studies. Human Health Safety Assessment Consumer: 2-Ethylhexyl acrylate is not used as a raw material in consumer product formulations. Therefore, no appreciable consumer exposures or associated health risks are anticipated. Worker: In industrial settings 2-ethylhexyl acrylate is manufactured and handled primarily in closed processes, which limit exposure. Based on good manufacturing processes and industrial hygiene, the occupational health risk associated with 2-ethylhexyl acrylate is low. Environmental Effects Environmental Exposures 2-Ethylhexyl acrylate is readily biodegradable and has moderate potential for bioaccumulation. If released into water, 2-ethylhexyl acrylate is expected to adsorb moderately to suspended solids and sediment. In air 2-ethylhexyl acrylate will be rapidly degraded. If released to soil, 2-ethylhexyl acrylate is expected to have moderate mobility. Volatilization from moist soil surfaces is expected to be an important fate process.. Environmental Hazard Assessment Aquatic toxicity Effect Assessment Result Highly toxic to aquatic organisms. Fate and behavior Result Biodegradation Readily biodegradable. Bioaccumulation potential Moderate potential to bioaccumulative (log Kow = 4.64) PBT / vpvb conclusion Not considered to be either PBT or vpvb.
Environmental Safety Assessment 2-Ethylhexyl acrylate is acutely toxic to aquatic organisms. In spite of a relatively high toxicity it is anticipated to present a low overall risk to aquatic environments. This conclusion is based on the fact that 2-ethylhexyl acrylate will be quickly removed from the aquatic environment through degradation, partitioning to sediment, and evaporation. Risk Management Recommendations Exposure to 2-ethylhexyl acrylate in the workplace can be controlled by sufficient ventilation, proper handling and storage techniques, and the use of appropriate personal protective equipment as recommended in the SDS. Consumer products are not anticipated to contain significant levels of 2-ethylhexyl acrylate. Occupational exposure limits are presented, below: MAK: 5 ppm, 38 mg/m 3 Regulatory Agency Review 2-Ethylhexyl acrylate is on the following lists: Australian Inventory of Chemical Substances (AICS) Austria - Occupational Exposure Limits (OELs) China - Chemical Inventory of Existing Chemical Substances (IECSC) - CAS Numbers DOE Protective Action Criteria (PAC) ECHA - List of Pre-registered Substances Environment Canada - Chemical Management Plan - Status of Prioritized Substances Environment Canada - Domestic Substances List (DSL) Environment Canada - Domestic Substances List (DSL) - Human Health Categorization Environment Canada - Domestic Substances List (DSL) Categorization of Existing Substances Environment Canada - Hazardous Products Act (HPA) - Ingredient Disclosure List (IDL) EPA - 40CFR - Table 1 to Subpart F of Part 63 Synthetic Organic Chemical Manufacturing Industry Chemicals EPA - Chemical Update System (CUS) - 2002 EPA - Inert Ingredients in Pesticide Products EPA - Inert Ingredients Permitted for Use In Nonfood Pesticide Products EPA - Master Testing List EPA - Master Testing List (1996) EPA - Office of Pollution Prevention and Toxics (OPPT) High Production Volume (HPV) Program - 1990 EPA - TSCA - 8(a) - Preliminary Assessment Information Rules (PAIR) EPA - TSCA - Chemical Hazard Information Profiles (CHIPS) EPA - TSCA - Inventory EPA - TSCA - Test Submissions - Section 4 ETUC - Priority List for REACH Authorisation EU - Cosmetic Ingredients and Fragrance Inventory EU - European Inventory of Existing Commercial Substances (EINECS) EU - High Production Volume Chemicals - Priority List 1 EU - Table 3.1 of Annex VI to the CLP Regulation EU - Table 3.2 of Annex VI to the CLP Regulation FDA - Inventory of Effective Food Contact Substance (FCS) Notifications FDA - List of Indirect Additives Germany - Occupational Exposure Limits (OELs) IARC- Group 3 Massachusetts Department of Public Health - Massachusetts Substance List (MSL) Mexico - National Inventory of Chemical Substances National Cancer Institute - SMILES Notations New Zealand - Inventory of Chemicals (NZIoC) NFPA - Hazard Ratings OECD - High Production Volume (HPV) Chemicals - 2004 OECD - High Production Volume (HPV) Chemicals - 2007 Pennsylvania - Hazardous Substance List
Philippine Inventory of Chemicals and Chemical Substances (PICCS) Poland - Occupational Exposure Limits (OELs) Rhode Island - Hazardous Substance List Russia - Occupational Exposure Limits (OELs) Switzerland - Occupational Exposure Limits (OELs) Technischen Regeln für Gefahrstoffe (TRGS) - TRGS900 Turkey - First List of Priority Substances Regulatory Information / Classification and Labeling Under the Globally Harmonized System for classification and labeling (GHS), substances are classified according to their physical, health, and environmental hazards. The hazards are communicated via specific labels and the (Extended) SDS. GHS attempts to standardize hazard communication so that the intended audience (workers, consumers, transport workers, and emergency responders) can better understand the hazards of the chemicals in use. GHS Classification: Skin Irritation, Category 2 Skin Sensitization, Category 1 Specific Target Organ Toxicity - Single Exposure (STOT-SE), Category 3 Hazard Statements: H315: Causes skin irritation H317: May cause allergic skin reaction H335: May cause respiratory irritation Signal Word: Warning Precautionary Statements: P210: Keep away from heat/sparks/open flames/hot surfaces. - No smoking. P261: Avoid breathing dust/ fume/gas/mist/vapors/spray. P264: Wash skin thoroughly after handling. P271: Use only outdoors or in a well-ventilated area. P272: Contaminated work clothing must not be allowed out of the workplace. P280: Wear eye protection/face protection/protective gloves. P302: IF ON SKIN: Wash with plenty of soap and water. P333: If skin irritation or rash occurs: Get medical advice/ attention. P337: If eye irritation persists: Get medical advice/ attention. P362: Take off contaminated clothing and wash before reuse. P370: In case of fire: Use dry sand, dry chemical or alcohol-resistant foam for extinction. P403: Store in a well-ventilated place. P405: Store locked up. P501: Dispose of contents/ container to an approved waste disposal plant Hazard Pictograms:
Conclusion 2-Ethylhexyl acrylate is used as a reactive component to produce polymers and copolymers, which are used in coatings and inks, adhesives, sealants, textiles, plastics and elastomers. Consumer products will not contain appreciable levels of 2-ethylhexyl acrylate and, therefore, exposure and health risks to consumers are considered negligible. In the occupational setting, responsible handling of 2-ethylhexyl acrylate will prevent the potential for skin or eye irritation and skin sensitization allowing workers to use materials containing 2-ethylhexyl acrylate safely. Contact Information with Company Ashland Inc. 5200 Blazer Parkway Dublin, Ohio 43017 http://www.ashland.com/contact Date of Issue: October 17, 2016 Revision: 1 Additional Information For more information on GHS, visit http://www.osha.gov/dsg/hazcom/ghsguideoct05.pdf or http://live.unece.org/trans/danger/publi/ghs/ghs_welcome_e.html. Ashland product stewardship summaries are located at http://www.ashland.com/sustainability/product/product-stewardship Disclaimer All statements, information and data presented herein are believed to be accurate and reliable, but are not to be taken as a guarantee, an express warranty, or an implied warranty of merchantability or fitness for a particular purpose, or representation, express or implied, for which Ashland Inc. and its subsidiaries assume legal responsibility. REACH registration is specific to Importers/Manufacturers that place the chemical on the EU market, and is specific to registered uses. Inclusion on the list of REACH Registered Substances does not automatically imply registration by Ashland. Inclusion on the New Zealand Inventory of Chemicals applies only to the pure substance listed. The importer of record must determine whether or not their substances are in compliance.