IPR M2i Tablet Press Pictures INDUSTRIAL PHARMACEUTICAL RESOURCES, INC PAGE 1 OF 3

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IPR M2i Tablet Press Pictures M2i Tablet Press Rotary Feeder INDUSTRIAL PHARMACEUTICAL RESOURCES, INC PAGE 1 OF 3

IPR M2i Tablet Press Pictures Upper Pressure Roll with Punch Penetration Drive Motor & Gearbox, Feeder Motor, and Overload System INDUSTRIAL PHARMACEUTICAL RESOURCES, INC PAGE 2 OF 3

SPECIFICATIONS OF IPR'S M2i TABLET PRESS M2i: 39, 51, 55, 61 Stations 1. General Specifications 2. Compression Sub-System 3. Feeding Sub-System 4. Drive Sub-System 5. Lubrication 6. Weight Control 7. Access, Cleanability and Tooling Changeover 8. Machine Control Sub-System (PLC) Outline - Ver. 2.0 IPR Confidential Page 1

Phone: 630-823-4700 1.0 General Specifications M2i Double Sided Press M2i Single Sided Press with Precompression Number of Stations: 39 51 55 61 39 51 55 61 1.11 Press Output Tablets Per Minute (TPM) 3,744 9,293 10,022 11,115 1,872 4,647 5,011 5,558 Tablets Per Hour (TPH) 224,640.00 557,593.20 601,326.00 666,925.20 112,320.00 278,796.60 300,663.00 333,462.60 Revolutions Per Minute (RPM) 48.00 91.11 91.11 91.11 48.00 10 Ton Main 10 91.11 6.5 Ton Main 91.11 6.5 Ton Main 91.11 6.5 Ton Main 1.12 Overload Pressure 10 Ton Main 6.5 Ton Main 6.5 Ton Main 6.5 Ton Main Ton Pre 6.5 Ton Pre 6.5 Ton Pre 6.5 Ton Pre 1.13 Depth of Fill (max) 13/16" 20.63mm 11/16" 17.46mm 11/16" 17.46mm 11/16" 17.46mm 13/16" 20.63mm 11/16" 17.46mm 11/16" 17.46mm 11/16" 17.46mm 1.14 Tablet Diameter (max) 1" 25.4mm 5/8" 15.87mm 7/16" 11.11mm 7/16" 11.11mm 1" 25.4mm 5/8" 15.87mm 7/16" 11.11mm 7/16" 11.11mm 1.15 Die Outer Diameter 1.5" 38.1mm 1.187" 30.16mm 0.945" 24mm 0.945" 24mm 1.5" 38.1mm 1.187" 30.16mm 0.945" 24mm 0.945" 24mm 1.16 Punch Size (Per TSM Specifications) D Size B Size BB Size BB Size D Size B Size BB Size BB Size 1.17 Upper Punch Entry 1/8" - 5/16" 3.1mm - 7.9mm 1/8" - 5/16" 3.1mm - 7.9mm 1.18 Height of Machine 1.19 Drive Motor Horsepower Speed (60 Cycle) 1.20 Dimensions Floor Space Space - Guards Open Height - Guards Open Approx. Net Weight (kg) 77.4" 77.4" 10 10 1800 RPM 1800 RPM 45.8" W x 59.1" D x 77.4" H 45.8" W x 59.1" D x 77.4" H 85.8" W x 87" D x 86" H 85.8" W x 87" D x 86" H 86" 86" 2360 Kg 2360 Kg NOTE: 1) All models are designed and manufactured to operate at maximum compaction forces of 10 tons (100 kn). B machines can be provided with 6.5 ton (65kN) tie rods which offer better sensitivity for weight control. Regardless of the tie rods used, the maximum compaction force will be dictated by the compressive strength of the punch tip. 2) * ates increased number of stations from standard turret. Stainless Steel Die Table required. General Specs. - Ver. 2.0 IPR Confidential Page 2

2. Compression Sub-System M2i Double Sided Press M2i Single Sided Press with Precompression 2.1 Turret 3 piece construction 3 piece construction Punch Seals Upper & Lower Punch Seals Upper & Lower Punch Seals Pitch Circle Diameter 53 cm 53 cm Upper & Lower Section Material Cast Iron construction Cast Iron construction Die Table Material 400 series Stainless Steel 400 series Stainless Steel 2.2 Camming Cycloidal Cycloidal B Fill Cams 5/16", 1/2", 11/16" 5/16", 1/2", 11/16" D Fill Cams 5/16", 9/16", 13/16" 5/16", 9/16", 13/16" Material High Density Plastic, Steel, or Aluminum Bronze High Density Plastic, Steel, or Aluminum Bronze Guards Lower Cam Guards Lower Cam Guards 2.3 Pressure Rolls One Piece with Pre-lubricated Sealed Bearings One Piece with Pre-lubricated Sealed Bearings Diameter 30 cm (Main Compression Roll) 30 cm (Main & Pre Compression Roll) Material D2 or A2 Steel D2 or A2 Steel Max Main Compression 10 tons 10 tons Max Pre Compression None 10 tons 2.4 Overload System Hydro-pneumatic with Adjustable Setting Hydro-pneumatic with Adjustable Setting Main Compression Rating 10 tons or 6.5 Tons 10 tons or 6.5 Tons Pre Compression Rating None 10 tons or 6.5 Tons 2.5 Strain Gauging Wheatstone Bridge Wheatstone Bridge Main Compression Element Tie Rod Tie Rod Pre Compression Element None Tie Rod or Roll Pin Compression System - Ver. 1.0 IPR Confidential Page 3

Phone: 630-823-4700 3. Feeding Sub-System 3.1 Feeder 3 Paddle, Tool-less Changeover w/ powder discharge chute Material Teflon Impregnated Anodized Aluminum Feeder Length 29 cm Feeder Platform Gimbal Mount 3.2 Feeder Regulation Three Paddles Variable Speed 0-60 RPM Inlet Diameter 4.0" 3.3 Feeder Control Gear Driven from beneath the tablet press Motor Lenze DC Motor with Gearbox RPM 3000 RPM Gearbox Ratio 25:1 Controller Lenze Controller Feeding System - Ver. 1.0 IPR Confidential Page 4

4. Drive Sub-System 4.1 Drive Arrangement Gearbox Ring Gear Rotation Direct Drive utilizing Variable Frequency Drive & Tooth Timing Belt Wormshaft with Ring Gear Transmitted by VFD Replaceable and mounted to the underside of the turret Clockwise 4.2 Drive Motor Three Phase, AC Induction RPM 300-1800 Horsepower 10 Turret Speed 10-91 RPM B Size Machine / 10-50 RPM D Size Machine 4.3 VFD Horsepower Brake Noise Enclosure CE Certified 15 HP Programmable Dynamic Brake Integral Noise Filters Protected Enclosure 4.4 Handwheel Safety Metal Handwheel to allow manual rotation of turret Protected By Interlocked Door and Located Inside of Press Drive System - Ver. 2.0 IPR Confidential Page 5

5. Lubrication Sub-System 5.1 Tooling Lubrication Punch Heads Upper Punch Barrels Lower Punch Barrels Intermittent Lubrication to Upper & Lower Punches Grease Applied to Upper & Lower Punch Heads via metering cam & timer Oil Applied to Upper Punch Barrels via felt pad & timer Oil Applied to Lower Punch Barrels via turret groove & timer 5.2 Centralized Lubrication Pressure Rolls Turret Drive Continuous Lubrication from totally enclosed oil reservoir Sealed Pre-lubricated Bearings Oil Applied via Turret Column & Bushings Oil Applied via Helical Gears & Bearings and Worm & Worm Wheel 5.3 Self Lubrication Feeder Weight Adjustment Compression Integrate Self Lubricating Parts where applicable Feeder gear train - phenolic & metal gears Weight adjustment mechanisms Pressure cylinder forks, trunions, pressure shafts 5.4 Maintenance Lubrication Motor Reservoirs Periodic Lubrication Requirements due to Press Maintenance Bearings Visual Sight Levels for Periodic Refilling 5.5 Lubrication Alarms Alarm 1 Alarm 2 Shutdown Press & Notify Operator Due To Insufficient Lubrication Low Circuit Pressure Low Oil Tank Level Lubrication - Ver. 1.0 IPR Confidential Page 6

6. Weight Control Sub-System 6.1 Punch Flight Flight Control Cam Threaded Punch Plug Provide resistance to Lower Punch for tight weight control Provide slight pull down of punch immediately following scrape-off Provide positive lower punch restraint with quick change feature 6.2 Tail-Over-Die Contact with Turret Material Cover filled die until upper punch enters the die Spring Loaded to float with die table High Density Plastic 6.3 Feeder Feeder Pan Head Pressure Three Paddle Variable Speed for optimum flow & weight control Flat within 0.001" for optimum yields Site glass to monitor feeder volume 6.4 Discard Chute Material Control Tablet Reject (Optional) Discard Tablets During Start-up & Shutdown Stainless Steel Timer Incorporated with PAC System to discard out-of-spec tablets 6.5 PAC System Hardware Software DSP Feature Recipe Drive Troubleshooting Quality Assurance Quality Control Control Tablet Weight & Reject Out-of-spec tablets via force feedback loop Standard off the shelf components Windows Compatible Digitize forces to analyze compression waveforms Reduce Changeover & Set-up Time Diagnosis Problems (I.e. Sticking punches, starved feeder/hopper, etc.) Real-time Process Validation & Weight Scale Feedback / Verification Reject out-of-tolerance tablets Weight Control - Ver. 1.0 IPR Confidential Page 7

7. Access, Cleanbility and Tooling Changeover Sub-System 7.1 Access Upper Access Lower Access Enclosures Round Pillar Construction with removable doors & guards 360 Degrees with 4 Hinged Guards 360 Degrees with 2 removable doors & 2 removable enclosures Removable panel to access electronic components 7.2 Tooling / De-tooling Lower Punches Upper Punches Feeder Support Plate Handwheel Provide quick & easy access to install & remove punches Single Piece Threaded Lower Punch Flight Restraint For Quick Changeover Removable retaining plate for installing & removing upper punches Removable insert to access die locks without removing feeder support plate Easy access to handwheel for turret rotation 7.3 Tool-less Features Feeder Assembly Cam Guards Scraper Assembly Lower Guards Provide tool-less features where applicable for quick changeover Incorporates tool-less design Thumb Screws for tool-less installation & removal Quick disconnect without removing feeder assembly Quick release handles to remove lower doors & enclosures 7.4 Dust Extraction Upper Guards Die Table Lower Cabinet Optional Feature Air Requirements Eliminate dust and reduce changeover time Downward Air Flow Two dust extraction covers with tool-less design Provide vacuum extraction at bottom of press Add dust extraction within lower cabinet for additional cleanliness 275 CFM @ 6" W.C. Access & Changeover - Ver. 1.0 IPR Confidential Page 8

8. Machine Control Sub-System (PLC) 8.1 Hardware 8.2 Drive System Specification User Interface Optional Feature Safety Alarms Manual Start/Stop Utilize a PLC for machine control Allen Bradley PLC 6" color touch screen 10" color touch screen Control start and stop of press via PLC Provide E-Stop on front & back of press Shutdown press if alarm occurs & display cause Manual Start / Stop Button also provided 8.3 Tablet Thickness LVDT Stepper Motor Thickness Assembly Controller Incorporate LVDT & Stepper motors to adjust tablet thickness Display Position of Compression Roll Pacific Scientific Motor located in roof of press Gear Driven Allen Bradley Controller 8.4 Feeder(s) 8.5 Lubrication 8.6 Air Pressure 8.7 Safety Alarm (Optional) Alarms Alarms Electronic Guards Alarms Display & Adjust Feeder Speeds via PLC touch screen Shutdown press via sensor in hopper or feeder inlet Control lubrication sub-systems via PLC Shutdown press due to low lubrication levels or pressure Control Hydraulic Overload Pressure Shutdown press due to low air pressure levels Electronic component & cabinet guards interlocked with main power Upper & Lower machine guards interlocked Shutdown & Alarm Display of individual door status Machine Control - Ver. 1.0 IPR Confidential Page 9