In-line diaphragm seal with sterile connection For sanitary applications Model , aseptic connection per DIN 11864

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Diaphragm seals In-line diaphragm seal with sterile connection For sanitary applications Model 981.51, aseptic connection per DIN 11864 WIKA data sheet DS 98.51 Applications For direct, quickly removable installation in pipelines For flowing, pure media Food and beverage production Pharmaceutical industry, biotechnology industry, production of active ingredients Production of aseptic basic materials in the chemical industry Special features Completely round diaphragm (Europ. Pat. No. 0609846) to avoid dead spaces Self-draining in all mounting positions Quick cleaning of measuring point, without residue Suitable for SIP and CIP EHEDG certified and 3-A compliant Description Diaphragm seals are used to protect the pressure measuring instrument from aggressive, adhesive, crystallising, corrosive, highly viscous, environmentally hazardous or toxic media. A diaphragm made of the appropriate material provides for the separation from the medium to be measured. Thus even the most difficult measuring requirements can be met by combining measuring instruments with diaphragm seals. A fluid inside the system, which can be chosen to suit the particular application, hydraulically transmits the pressure to the measuring instrument. Almost limitless application possibilities exist due to the large number of available variants, such as diaphragm seal designs or materials. The type of process connection (flange, threaded and sterile connection) and the basic method of manufacture are important design differentiation criteria. For further technical information on diaphragm seals and diaphragm seal systems see IN 00.06 Application, operating principle, designs. In-line diaphragm seal with sterile connection, model 981.51 The model 981.51 in-line diaphragm seal with aseptic connection per DIN 11864 can be mounted directly into the pipeline, meaning no special measuring point connection is required. Through the integration into the process line, turbulences, dead spaces, corners and other obstructions can be avoided. For this diaphragm seal WIKA uses a completely round diaphragm, which, due to the unobstructed flow of the media, produces an automatic cleaning of the chamber. The diaphragm seal systems can withstand the cleaning vapour temperatures occurring in the SIP processes and thus ensure a sterile connection between the medium to be measured and the diaphragm seal. Assembly of the diaphragm seal and measuring instrument is made via a direct assembly as standard or optionally via a cooling element or a flexible capillary. For the material selection WIKA offers a variety of solutions, in which the main body and the diaphragm are made of identical materials. Stainless steel 316L (1.4435) is used as standard material, other special materials are available on request. Measuring systems with model 981.51 WIKA diaphragm seals are successfully used in the life science industry, in food production, pharmaceutical and biotechnology applications. WIKA data sheet DS 98.51 09/2016 Page 1 of 7 Data sheets showing similar products: Version with thread; model 981.18... 21; see data sheet DS 98.40 Version with NEUMO BioConnect ; model 981.50; see data sheet DS 98.50 Version with clamp connection; models 981.22, 981.52 and 981.53; see data sheet DS 98.52

Standard version Type of process connection connection per DIN 11864, sealing form A threaded pipe connection per DIN 11864-1 flange connection per DIN 11864-2 clamp connection per DIN 11864-3 For pipes per DIN 11866 row A and row B (or DIN 11850 and DIN EN ISO 1127) For exact designs and nominal widths see tables on page 4 to 6 Nominal pressure see tables on page 4 to 6 Measuring ranges Threaded connection: 0... 0.6 bar to 0... 40 bar (to DN 40) 0... 0.6 bar to 0... 25 bar (from DN 50) Flange connection: 0... 0.6 bar to 0... 25 bar (to DN 40) 0... 0.6 bar to 0... 16 bar (from DN 50) Clamp connection: 0... 0.6 bar to 0... 40 bar (to DN 40) 0... 0.6 bar to 0... 25 bar (to DN 65) 0... 0.6 bar to 0... 16 bar (from DN 80) (also vacuum and +/- measuring ranges) Material of main body Stainless steel 1.4435 (316L) Material of wetted parts Diaphragm: Stainless steel 1.4435 (316L) Surface roughness of wetted parts Ra 0.76 µm per ASME BPE SF3 (except for weld seam) Installation example In-line diaphragm seal, sterile connection, model 981.51 with directly assembled pressure gauge in a pipeline Level of cleanliness of wetted parts Oil and grease free per ASTM G93-03 level E (WIKA standard) and ISO 15001 (< 550 mg/m 2 ) Connection to the measuring instrument Axial weld-in connection Options Other nominal widths and aseptic connections on request Surface roughness of wetted parts Ra 0.38 µm per ASME BPE SF4, only with electropolished surface (except for weld seam) connection per DIN 11864, sealing form B Connection to the measuring instrument G 1/2, G 1/4, 1/2 NPT or 1/4 NPT (female) Origin of wetted parts (EU, CH, USA) Marking of the diaphragm seal in accordance with the applicable 3-A standard Materials Upper body Standard Stainless steel 1.4435 (316L) Option Stainless steel 1.4435 (316L), electropolished Stainless steel 1.4539 (904L) Wetted part: Diaphragm Stainless steel 1.4435 (316L) Stainless steel 1.4435 (316L), electropolished Stainless steel 1.4539 (904L) Hastelloy C276 (2.4819) Hastelloy C276 (2.4819) Hastelloy C22 (2.4602) Hastelloy C22 (2.4602) Further material combinations on request Pressure measuring instrument (pressure gauge or transmitter) Direct assembly Diaphragm seal Diaphragm, in-line diaphragm (welded with diaphragm seal) Grooved union nut Sealing Welding socket Not included in delivery P4_Z_1889.02 Page 2 of 7 WIKA data sheet DS 98.51 09/2016

Additional information for diaphragm seal systems See Technical information IN 00.06 Diaphragm seals, application, operating principle, designs Pressure measuring instrument model Connection to the measuring instrument: Direct assembly (for types of instrument connection see below, calibrated in the mounting position selected for the in-line diaphragm seal) Process temperature Ambient temperature System fill fluid - Recommendation for the food and beverage production: Neobee KN 59 (FDA 21 CFR 172.856, 21 CFR 174.5) - Recommendation for pharmaceutical and cosmetics applications: Medicinal white mineral oil KN 92 (FDA 21 CFR 172.878, 21 CFR 178.3620(a); USP, EP, JP) Options for diaphragm seal systems Connection to the measuring instrument via cooling element or capillary Further pressure measuring instruments possible Vacuum service (suitable for vacuum operation) Higher level of cleanliness of wetted parts Oil and grease free per ASTM G93-03 level C and ISO 15001 (< 66 mg/m 2 ) Height difference between measuring point and pressure measuring instrument with capillary in metre increments (max. 7 m with silicone oils/edible oils) Mounting bracket (required for connection to the measuring instrument via capillary, model 910.16, data sheet AC 09.07) - Form H per DIN 16281, 100 mm, aluminium, black - Form H per DIN 16281, 100 mm, stainless steel - Bracket for pipe mounting, for pipe Ø 20... 80 mm, steel Special version - Complete measuring assembly autoclavable, on request Assembly of the pressure measuring instrument For s Variant 1 Lower mount (LM) Variant 2 Lower mount (LM) - Pointer shaft: Parallel to flow Variant 3 Lower back mount (LBM) For vertical pipelines Variant 1 Connection location at 3 o'clock vertical pipeline Variant 2 Connection location at 9 o'clock vertical pipeline Variant 3 Lower back mount (LBM) vertical pipeline Variant 4 Connection location at 12 o'clock WIKA data sheet DS 98.51 09/2016 Page 3 of 7

Dimensions in mm Type of process connection: threaded pipe connection DIN 11864-1 form A (O-ring) Specification of the process connection: With collar connecting sleeve and grooved union nut or with threaded coupling with collar connecting sleeve and grooved union nut with threaded coupling Assembly alternatively by direct welding or via capillary 2411720.02 2411712.02 F Legend: Ø Mb Effective diameter of diaphragm Ø G 1 Thread F Grooved union nut (form F) per DIN 11851 Pipe standard: Pipes per DIN 11866 row A or DIN 11850 row 2 L Mb d 6 d 11 G D b O-ring 25 29 x 1.5 40 128 26 42.9 43 RD 52 x 1/6 63 14 28 x 3.5 32 35 x 1.5 40 128 32 48.9 49 RD 58 x 1/6 70 14 34 x 5 40 41 x 1.5 40 160 38 54.9 55 RD 65 x 1/6 78 14 40 x 5 50 53 x 1.5 25 170 50 66.9 67 RD 78 x 1/6 92 14 52 x 5 65 70 x 2 25 182 66 84.9 85 RD 95 x 1/6 112 16 68 x 5 80 85 x 2 25 182 81 98.9 99 RD 110 x 1/4 127 20 83 x 5 100 104 x 2 25 182 100 118.9 119 RD 130 x 1/4 148 20 102 x 5 Pipe standard: Pipes per DIN 11866 row B or DIN ISO 1127 row 1 L Mb d 6 d 11 G D b O-ring 26.9 26.9 x 1.6 40 128 23.7 42.9 43 RD 52 x 1/6 63 14 26 x 3.5 33.7 33.7 x 2.0 40 128 29.7 48.9 49 RD 58 x 1/6 70 14 32 x 5 42.4 42.4 x 2.0 25 160 38.4 54.9 55 RD 65 x 1/6 78 14 40.5 x 5 48.3 48.3 x 2.0 25 170 44.3 66.9 67 RD 78 x 1/6 92 14 46.5 x 5 60.3 60.3 x 2.0 25 182 56.3 84.9 85 RD 95 x 1/6 112 16 58.5 x 5 76.1 76.1 x 2.0 25 182 72.1 98.9 99 RD 110 x 1/4 127 20 73.5 x 5 88.9 88.9 x 2.3 25 182 84.3 118.9 119 RD 130 x 1/4 148 20 86.5 x 5 Pipe standard: Pipes per DIN 11866 row C or ASME BPE 1997 L Mb d 6 d 11 G D b O-ring 1" 25.4 x 1.65 40 128 22.1 42.9 43 RD 52 x 1/6 63 14 24 x 3.5 1 ½" 42.4 x 1.65 40 160 34.8 54.9 55 RD 65 x 1/6 78 14 37 x 5 2" 48.3 x 1.65 25 170 47.5 66.9 67 RD 78 x 1/6 92 14 50 x 5 2 ½" 60.3 x 1.65 25 182 60.2 84.9 85 RD 95 x 1/6 112 16 62 x 5 3" 76.1 x 1.65 25 182 72.9 98.9 99 RD 110 x 1/4 127 20 75 x 5 4" 88.9 x 2.11 25 182 97.4 118.9 119 RD 130 x 1/4 148 20 100 x 5 1) Permissible pressure in bar; these pressures may only be applied when using suitable sealing materials up to a temperature from -10 to +140 C. Page 4 of 7 WIKA data sheet DS 98.51 09/2016

Type of process connection: flange connection DIN 11864-2 form A (O-ring) Specification of the process connection: With aseptic flange with groove or with flange with notch with flange with groove with flange with notch Assembly alternatively by direct welding or via capillary 2411941.02 Legend: Ø Mb Effective diameter of diaphragm b 1 Flange width for aseptic flange with groove b 2 Flange width for aseptic flange with notch 11147202.02 Pipe standard: Pipes per DIN 11866 row A or DIN 11850 row 2 L Mb d 5 d 6 d 13 d 11 d 10 b 1 b 2 O-ring 25 29 x 1.5 40 128 26 53 38.3 4 x Ø 9 38.4 70 11.5 10 28 x 3.5 32 35 x 1.5 40 128 32 59 47.6 4 x Ø 9 47.7 76 11.5 10 34 x 5 40 41 x 1.5 40 160 38 65 53.6 4 x Ø 9 53.7 82 11.5 10 40 x 5 50 53 x 1.5 25 170 50 77 65.6 4 x Ø 9 65.7 94 11.5 10 52 x 5 65 70 x 2 25 182 66 95 81.6 8 x Ø 9 81.7 113 11.5 10 68 x 5 80 85 x 2 25 182 81 112 97.6 8 x Ø 11 97.7 133 13.5 12 83 x 5 100 104 x 2 25 182 100 137 116.6 8 x Ø 11 116.7 159 13.5 14 102 x 5 Pipe standard: Pipes per DIN 11866 row B or DIN ISO 1127 row 1 L Mb d 5 d 6 d 13 d 11 d 10 b 1 b 2 O-ring 26.9 26.9 x 1.6 40 128 23.7 52 36 4 x Ø 9 36.1 69 11.5 10 26 x 3.5 33.7 33.7 x 2.0 40 128 29.7 57 45.3 4 x Ø 9 45.4 74 11.5 10 32 x 5 42.4 42.4 x 2.0 25 160 38.4 65 54 4 x Ø 9 54.1 82 11.5 10 40.5 x 5 48.3 48.3 x 2.0 25 170 44.3 71 59.9 4 x Ø 9 60 88 11.5 10 46.5 x 5 60.3 60.3 x 2.0 25 182 56.3 85 71.9 4 x Ø 9 72 103 11.5 10 58.5 x 5 76.1 76.1 x 2.0 25 182 72.1 104 88.1 8 x Ø 11 88.2 125 13.5 12 73.5 x 5 88.9 88.9 x 2.3 25 182 84.3 116 100.9 8 x Ø 11 101 137 13.5 12 86.5 x 5 Pipe standard: Pipes per DIN 11866 row C or ASME BPE 1997 L Mb d 5 d 6 d 13 d 11 d 10 b 1 b 2 O-ring 1" 25.4 x 1.65 40 128 22.1 49 34.3 4 x Ø 9 34.4 66 11.5 10 24 x 3.5 1 ½" 42.4 x 1.65 40 160 34.8 62 50.4 4 x Ø 9 50.5 79 11.5 10 37 x 5 2" 48.3 x 1.65 25 170 47.5 75 63.4 4 x Ø 9 63.5 92 11.5 10 50 x 5 2 ½" 60.3 x 1.65 25 182 60.2 89 75.8 8 x Ø 9 75.9 107 11.5 10 62 x 5 3" 76.1 x 1.65 25 182 72.9 104 89.5 8 x Ø 11 89.6 125 13.5 12 75 x 5 4" 88.9 x 2.11 25 182 97.4 135 114.2 8 x Ø 11 114.3 157 13.5 14 100 x 5 1) Permissible pressure in bar; these pressures may only be applied when using suitable sealing materials up to a temperature from -10 to +140 C. WIKA data sheet DS 98.51 09/2016 Page 5 of 7

Type of process connection: clamp connection DIN 11864-3 form A (O-ring) Specification of the process connection: With clamp with groove or with clamp with notch with clamp with groove with clamp with notch Assembly alternatively by direct welding or via capillary 11147075.02 Legend: Ø Mb Effective diameter of diaphragm 11147105.02 Pipe standard: Pipes per DIN 11866 row A or DIN 11850 row 2 L Mb d 6 d 11 d 10 O-ring 25 29 x 1.5 40 114 26 38.3 38.4 50.5 28 x 3.5 32 35 x 1.5 40 146 32 47.6 47.7 50.5 34 x 5 40 41 x 1.5 40 146 38 53.6 53.7 64 40 x 5 50 53 x 1.5 25 156 50 65.6 65.7 77.5 52 x 5 65 70 x 2 25 156 66 81.6 81.7 91 68 x 5 80 85 x 2 16 156 81 97.6 97.7 106 83 x 5 100 104 x 2 16 156 100 116.6 116.7 130 102 x 5 Pipe standard: Pipes per DIN 11866 row B or DIN ISO 1127 row 1 L Mb d 6 d 11 d 10 O-ring 26.9 26.9 x 1.6 40 114 23.7 36 36.1 50.5 26 x 3.5 33.7 33.7 x 2.0 40 114 29.7 45.3 45.4 50.5 32 x 5 42.4 42.4 x 2.0 25 146 38.4 54 54.1 64 40.5 x 5 48.3 48.3 x 2.0 25 146 44.3 59.9 60 64 46.5 x 5 60.3 60.3 x 2.0 25 156 56.3 71.9 72 91 58.5 x 5 76.1 76.1 x 2.0 25 156 72.1 88.1 88.2 106 73.5 x 5 88.9 88.9 x 2.3 25 156 84.3 100.9 101 119 86.5 x 5 Pipe standard: Pipes per DIN 11866 row C or ASME BPE 1997 L Mb d 6 d 11 d 10 O-ring 1" 25.4 x 1.65 40 114 22.1 34.3 34.4 50.5 24 x 3.5 1 ½" 42.4 x 1.65 40 145 34.8 50.4 50.5 64 37 x 5 2" 48.3 x 1.65 25 156 47.5 63.4 63.5 77.5 50 x 5 2 ½" 60.3 x 1.65 25 156 60.2 75.8 75.9 91 62 x 5 3" 76.1 x 1.65 25 156 72.9 89.5 89.6 106 75 x 5 4" 88.9 x 2.11 25 156 97.4 114.2 114.3 130 100 x 5 1) Permissible pressure in bar; these pressures may only be applied when using suitable sealing materials up to a temperature from -10 to +140 C. Page 6 of 7 WIKA data sheet DS 98.51 09/2016

Approvals Logo Description Country EU declaration of conformity European Union Pressure equipment directive 3-A USA Sanitary Standard EHEDG Hygienic Equipment Design European Union Certificates (option) 2.2 test report per EN 10204 (e.g. state-of-the-art manufacturing, material proof, indication accuracy for diaphragm seal systems) 3.1 inspection certificate per EN 10204 (e.g. material proof for wetted metallic parts, indication accuracy for diaphragm seal systems) FDA conformity of the system fill fluid 3-A conformity of the diaphragm seal, based on a third party verification EHEDG conformity Manufacturer s declaration for food contact materials regarding regulation (EC) No. 1935/2004 Others on request Approvals and certificates, see website Ordering information Diaphragm seal: Diaphragm seal model / Process connection (type and specification of process connection, pipe standard, pipe dimension) / Material (base body, diaphragm) / Surface roughness of wetted parts / Sealing form / Zero point stabilisation (ZPS) / Connection to the measuring instrument / Level of cleanliness of wetted parts / Origin of wetted parts / Certificates Diaphragm seal system: Diaphragm seal model / Process connection (type and specification of process connection, pipe standard, pipe dimension) / Material (base body, diaphragm) / Surface roughness of wetted parts / Sealing form / Zero point stabilisation (ZPS) / Pressure measuring instrument model (per data sheet) / Assembly (direct assembly horizontal/vertical, cooling element horizontal/ vertical, capillary) / min. and max. process temperature / min. and max. ambient temperature / Vacuum service / System fill fluid / Certificates / Height difference / Level of cleanliness of wetted parts / Origin of wetted parts / Mounting bracket 06/2003 WIKA Alexander Wiegand SE & Co. KG, all rights reserved. The specifications given in this document represent the state of engineering at the time of publishing. We reserve the right to make modifications to the specifications and materials. 09/2016 EN WIKA data sheet DS 98.51 09/2016 Page 7 of 7 WIKA Alexander Wiegand SE & Co. KG Alexander-Wiegand-Straße 30 63911 Klingenberg/Germany Tel. +49 9372 132-0 Fax +49 9372 132-406 info@wika.de www.wika.de