Bringing Renewable Elastomers to Market

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Bringing Renewable Elastomers to Market Damien Perriman Vice President, Business Development May 14, 2014

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GENO Genomatica Process Technologies from fossil fuels to alternative feedstock A better way to make chemicals exact same chemicals better economics smaller footprint 3

1 st Commercial: The GENO BDO Process Licensed to BASF, Novamont Sugars $4Bn Biomass A better way to make BDO: Smaller environmental footprint Safer Better economics 4

Genomatica Recognized as a Clear Leader technology platform, BDO process, industry leadership, corporate culture 2014 Winner 5

BUTADIENE Integral part of important value chains SBR (32%) PBR (29%) ABS (12%) Latex (10%) Brands

On-purpose Butadiene: Addressing the Need Customer Needs Access to new butadiene supply Balancing supply with demand Economic viability Help with establishing the new value chain Solution Process technology from new feedstock On-purpose production of ingredients Access to new raw materials reduces dependency on fossil fuels Partnerships to develop and commercialize and renewable. 7

Shale Gas Transforming Supply Chains Worldwide The Shale Oil Boom is Going Global Dr. Kent Moors, July 18th, 2013 8

Natural Gas Liquids Industry Feedstock Shift Opportunities for On-Purpose C4 Production, and Use of Natural Gas Abundant availability of shale gas leading to use of natural gas liquids (ethane, propane, butane) for petrochemical production Prime beneficiary is ethylene and derivatives of C2 chemicals Shortfall in output of major co-products produced with ethylene production including propylene (C3), butadiene (C4), benzene (C6) On-purpose C3 production expanding to meet shortfall Limited on-purpose options for C4 production U.S. Cracker Output of Co-Products (as % of Total Ethylene Output) Propylene C3 Butadiene C4 Benzene C6 30% 10% 10% 25% 8% 8% 20% 15% 10% 5% ~42% decline vs. high in 2002 6% 4% 2% ~40% decline vs. high in 2005 6% 4% 2% ~47% decline vs. high in 2001 VALUE CHAINS FOR BDO AND MEG Case BDO Syngas / Methane Methanol Methane Formaldehyde Acetylene BDO Sugar BDO 0% 2000 2005 2010 2015 2020 0% 2000 2005 2010 2015 2020 0% 2000 2005 2010 2015 2020 9

New butadiene supply required to meet consumption forecast Presented by Rand Rabenhorst, Principal, Nexant Inc Dec 2013, ICIS Butadiene Americas Conference 10

Genomatica s 2 nd Process: Butadiene (BDE) Fast start with $100M in industry support and commercialization intent $20B ENI Versalis and Braskem invested as first sponsors Joint development for multiple pathways and feedstocks 11

Versalis: JV for butadiene Process technology for on-purpose butadiene from biomass #1 Italian chemical company #2 BDE producer in Europe ENI subsidiary A united approach Biomass to polymer-grade butadiene Versalis to build first commercial plants Shared licensing revenues Biomass Fermentable sugars 1,3-BDO Intermediate Butadiene Elastomers 12

Braskem: Joint Development for Butadiene Funded development, plans for first plants in Americas Funded development for sugar to butadiene Build pilot & demonstration plants Certain rights for commercial plants in the Americas #1 producer of biopolymers in the world #3 producer of butadiene in the world Shared licensing revenues Sucrose Butadiene 13

Example: Direct Production of Butadiene Figure below from issued U.S. patent 8,580,543 (issued Nov 2013)

Enables technologies to reach major markets worldwide Bio-Butadiene Process Technologies 15

Opportunities for more partners to add momentum Technology access Feedstock supply Sustainable marketing Sampling Prepaid license or license option Access to earlyadopter incentives 16

Thank You Damien Perriman dperriman@genomatica.com Follow 17