Five Years of Accelerator Operation Experience at HIT Andreas Peters Heidelberg Ion Beam Therapy Centre (HIT), Head Accelerator Operations

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Five Years of Accelerator Operation Experience at HIT Andreas Peters Heidelberg Ion Beam Therapy Centre (HIT), Head Accelerator Operations HIT Betriebs GmbH am Universitätsklinikum Heidelberg http://www.hit-centrum.de

Outline The HIT Facility A Short Overview From Commissioning by GSI to Operation by HIT Five Years of HIT Accelerator Operation at a Glance Continuous Improvement Process Examples: Ion Source and RFQ Test Bench Magnetic Field Control in the Synchrotron ACS Optimization Dynamic Intensity Control Acknowledgements IPAC12, New Orleans, USA, 22 nd May 2012 2

The HIT Facility A Short Overview HIT: Heidelberg Ion Beam Therapy Centre University Campus Im Neuenheimer Feld IPAC12, New Orleans, USA, 22 nd May 2012 3

The HIT Facility A Short Overview HIT: Heidelberg Ion Beam Therapy Centre University Campus Im Neuenheimer Feld HIT is located directly beside the National Centre for Tumour Diseases (NCT) and university hospitals IPAC12, New Orleans, USA, 22 nd May 2012 4

The HIT Facility A Short Overview IPAC12, New Orleans, USA, 22 nd May 2012 5

The HIT Facility A Short Overview Ion sources and Linac Synchrotron Gantry To Experiment Place Three Irradiation rooms; Patient Treatment started 15 th Nov, 2009 IPAC12, New Orleans, USA, 22 nd May 2012 6

The HIT Facility A Short Overview HIT synchrotron p: 48 221 MeV C: 88 430 MeV/u (255 energy steps, also for O and He) Patient positioning in horizontal treatment room (medical equipment IONTRIS by Siemens) IPAC12, New Orleans, USA, 22 nd May 2012 7

From Commissioning by GSI to Operation by HIT Commissioning Steps: June 2007 2006 Ion Sources and Linac Hand-over to HIT: 06/2007 2007/08 Synchrotron and HEBT Lines Hand-over to HIT: 04/2008 February 2007 March 2007 April 2008 IPAC12, New Orleans, USA, 22 nd May 2012 8

Five Years of HIT Accelerator Operation Building up of the team from a core to the full operating crew Training of the team done by GSI, companies and in-house Internal organization of three technical teams Establish regular shift operation from 16/5 to 24/7 for further commissioning steps including therapy control system evaluation IPAC12, New Orleans, USA, 22 nd May 2012 9

Five Years of HIT Accelerator Operation Building up of the team from a core to the full operating crew Training of the team done by GSI, companies and in-house Internal organization of three technical teams Establish regular shift operation from 16/5 to 24/7 for further commissioning steps including therapy control system evaluation Troubleshooting: e.g. a destroyed magnet connection box repair within two days IPAC12, New Orleans, USA, 22 nd May 2012 10

Five Years of HIT Accelerator Operation Establish routine operation of the accelerator, especially consolidation of control system Achieved availability of about 98% in average no longer break than 3 hours at daytime Daily Accelerator QA retuning of linac, synchrotron and HEBT only every 3 4 months except intensity readjusting (weekly) IPAC12, New Orleans, USA, 22 nd May 2012 11

Five Years of HIT Accelerator Operation Establish routine operation of the accelerator, especially consolidation of control system Achieved availability of about 98% in average no longer break than 3 hours at daytime Daily Accelerator QA retuning of linac, synchrotron and HEBT only every 3 4 months except intensity readjusting (weekly) Patients treatment started on 15th November 2009 in one horizontal room Daily intensity checks (position and profiles) IPAC12, New Orleans, USA, 22 nd May 2012 12

Five Years of HIT Accelerator Operation Establish routine operation of the accelerator, especially consolidation of control system Achieved availability of about 98% in average no longer break than 3 hours at daytime Daily Accelerator QA retuning of linac, synchrotron and HEBT only every 3 4 months except intensity readjusting (weekly) Patients treatment started on 15th November 2009 in one horizontal room Daily intensity checks (position and profiles) IPAC12, New Orleans, USA, 22 nd May 2012 13

Five Years of HIT Accelerator Operation IPAC12, New Orleans, USA, 22 nd May 2012 14

Five Years of HIT Accelerator Operation Restart of beam optical commissioning of the gantry after solving severe problems with the drag chain IPAC12, New Orleans, USA, 22 nd May 2012 15

Five Years of HIT Accelerator Operation Restart of beam optical commissioning of the gantry after solving severe problems with the drag chain 37,000 settings per ion needed, but only ~ 1% interpolation points are needed adjustment sustained by an ion optical code (MIRKO by GSI) IPAC12, New Orleans, USA, 22 nd May 2012 16

Five Years of HIT Accelerator Operation Restart of beam optical commissioning of the gantry after solving severe problems with the drag chain 37,000 settings per ion needed, but only ~ 1% interpolation points are needed adjustment sustained by an ion optical code (MIRKO by GSI) Accuracy achieved: Pencil beam within limits for scanning possible treatment field 180 x 180 mm 2 ; long-term stability under test now Courtesy by A.v.Knobloch, Siemens IPAC12, New Orleans, USA, 22 nd May 2012 17

Five Years of HIT Accelerator Operation 2012 Year of the Gantry : Patient treatment start scheduled for end of October Major change in shutdown strategy during longer maintenance breaks of 2-3 weeks patients have to be phased out Ramping down and ramping up necessary Since 2012 instead of two long shutdowns now six short maintenance periods of four days each (effectively 2.5 days) Feasibility was successfully demonstrated! (Summer 2011) IPAC12, New Orleans, USA, 22 nd May 2012 18

Five Years of HIT Accelerator Operation 2012 Year of the Gantry : Patient treatment start scheduled for end of October Major change in shutdown strategy during longer maintenance breaks of 2-3 weeks patients have to be phased out Ramping down and ramping up necessary Since 2012 instead of two long shutdowns now six short maintenance periods of four days each (effectively 2.5 days) Feasibility was successfully demonstrated! HIT accelerator team members during May shutdown IPAC12, New Orleans, USA, 22 nd May 2012 19

Five Years of HIT Accelerator Operation - Statistics 1200 1000 800 Total Shifts (Numbers for 2012-2014 estimated) 600 Operation days 400 200 0 2007 2008 2009 2010 2011 2012 2013 2014 Treatment days Patients treated 2013: Major Upgrade of IONTRIS Treatment Software Year IPAC12, New Orleans, USA, 22 nd May 2012 20

Ion Source and RFQ Test Bench A test bench was set-up to study a very compact ion source/lebt version for proton and He beams to minimize space charge effects Introducing a four electrode extraction system in the ion source lead to more brilliant beams Modification of one ion source branch in the production machine already done in 2011 IPAC12, New Orleans, USA, 22 nd May 2012 21

Ion Source and RFQ Test Bench Before Upgrade IPAC12, New Orleans, USA, 22 nd May 2012 22

Ion Source and RFQ Test Bench Before Upgrade After Upgrade IPAC12, New Orleans, USA, 22nd May 2012 23

Ion Source and RFQ Test Bench After the ion source tests the enhanced RFQ version with a new input radial matcher (design: GSI) and better alignment was installed. IPAC12, New Orleans, USA, 22 nd May 2012 24

Ion Source and RFQ Test Bench After the ion source tests the enhanced RFQ version with a new input radial matcher (design: GSI) and better alignment was installed. IPAC12, New Orleans, USA, 22 nd May 2012 25

Ion Source and RFQ Test Bench After the ion source tests the enhanced RFQ version with a new input radial matcher (design: GSI) and better alignment was installed. First tests in April May this year with rebuncher at first in dummy position showed promising results with transmissions up to 60% - the investigations are ongoing. IPAC12, New Orleans, USA, 22 nd May 2012 26

Magnetic Field Control in the Synchrotron Magnetic effects cause dead times: Dipoles Eddy currents have to die out before extraction process Development of high sensitive measuring and feedback system IPAC12, New Orleans, USA, 22 nd May 2012 27

Magnetic Field Control in the Synchrotron Magnetic effects cause dead times: Dipoles Eddy currents have to die out before extraction process Development of high sensitive measuring and feedback system IPAC12, New Orleans, USA, 22 nd May 2012 28

Magnetic Field Control in the Synchrotron Magnetic effects cause dead times: Dipoles Eddy currents have to die out before extraction process Development of high sensitive measuring and feedback system System in use since end of 2011: Long-term stability successfully demonstrated; time saving per synchrotron cycle: 600 ms See poster THPPD002 for more details! A similar system will be used for the quadrupoles to avoid washing procedures needed because of hysteresis effects IPAC12, New Orleans, USA, 22 nd May 2012 29

ACS Optimization After running the accelerator for some time an initiative was started to optimize the control system while maintaining the high safety level needed for patient treatment Example: Shortening of the dead time between machine cycles --> huge amount of database operations take place. Detailed analysis lead to optimized table structures and access strategies. In addition, server hardware significantly updated. Saving: ~100 ms IPAC12, New Orleans, USA, 22 nd May 2012 30

Dynamic Intensity Control HIT uses scanned beams for tumour treatment Treatment time per voxel ~ some ms (Animation by courtesy of Siemens) IPAC12, New Orleans, USA, 22 nd May 2012 31

Dynamic Intensity Control HIT uses scanned beams for tumour treatment Adjustable but predefined amplitude curve drive the transverse RFknockout exciter producing more or less rectangular shaped spills. A feedback loop has been implemented to avoid imperfections see. Next step: A dynamic intensity adaptation during one spill with respect to the particular treatment plan is under investigation. IPAC12, New Orleans, USA, 22 nd May 2012 32

Dynamic Intensity Control HIT uses scanned beams for tumour treatment Adjustable but predefined amplitude curve drive the transverse RFknockout exciter producing more or less rectangular shaped spills. A feedback loop has been implemented to avoid imperfections see. Next step: A dynamic intensity adaptation during one spill with respect to the particular treatment plan is under investigation. See THEPP06 for more details! Treatment time per voxel ~ some ms (Animation by courtesy of Siemens) IPAC12, New Orleans, USA, 22 nd May 2012 33

Dynamic Intensity Control HIT uses scanned beams for tumour treatment Adjustable but predefined amplitude curve drive the transverse RFknockout exciter producing more or less rectangular shaped spills. A feedback loop has been implemented to avoid imperfections see. Next step: A dynamic intensity adaptation during one spill with respect to the particular treatment plan is under investigation. Shortening of treatment times of 20 40% possible! IPAC12, New Orleans, USA, 22 nd May 2012 34

Acknowledgement I would like to express my gratitude to my co-authors Rainer Cee, Eike Feldmeier, Michael Galonska, Thomas Haberer, Klaus Höppner, Stefan Scheloske, Christian Schömers and Tim Winkelmann as well as the whole HIT accelerator team for valuable discussions and for providing me their material used in the talk and in the proceedings. Thank you! And thank you for your attention! IPAC12, New Orleans, USA, 22 nd May 2012 35