CANCER of the KIDNEY and RENAL PELVIS

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1 CANCER of the KIDNEY and RENAL PELVIS Data Highlights There were 1,695 cases of cancer of the kidney and renal pelvis diagnosed in 1997 among residents of Pennsylvania, the highest annual number since statewide reporting began in Males had an average annual ( ) age-adjusted incidence rate about twice that of females (14.1 and 7.1 per 1,, respectively). Annual numbers of cases and age-adjusted incidence rates by sex and race for 1988 through 1997 have all been on the increase. There are few understood causes of kidney cancer; however, cigarette smoking is an important risk factor. Approximately a quarter of all cases are caused by this behavior. As with age-adjusted rates, age-specific incidence rates were much higher among males for almost all age groups. Fifty-eight percent of all the cases for 1997 were diagnosed during the local stage of the disease. During the five-year period of , over 7 percent of the cases of kidney and renal pelvis cancers were diagnosed among residents 6 years of age or older. In 1997, there were 631 resident deaths due to cancer of the kidney and renal pelvis, the highest annual number recorded between 1988 and The average annual ( ) age-adjusted death rate (3.5 per 1,) was over 65 percent lower than the average annual incidence rate (1.1 per 1,). The death rates were also much higher for males, as occurred with the incidence rates. There were no apparent trends for the mortality rates among the four sex/race groups. FIGURE 18 Average Annual Age-Adjusted Incidence and Mortality Rates* by Sex and Race, Incidence Mortality Race/Sex All Cases/Deaths All Males All Females Age-Adjusted Rate Risk Factors Cigarette smoking. Etiological factors are obscure. *per 1, 197 U.S. standard million population. Early Detection None proven to be effective or currently being evaluated. Pennsylvania Department of Health - Pennsylvania Cancer Incidence and Mortality Page 156

2 Cancer of the Kidney and Renal Pelvis: INCIDENCE TABLE 18-A Number of Cancer Cases, Age-Adjusted Incidence Rates and Range for 95% Confidence Intervals by Sex, Race and Year, Pennsylvania Residents, All Cases* All Races* White Black All Races* White Black Year No. Rate CI+/- No. Rate CI+/- No. Rate CI+/- No. Rate CI+/- No. Rate CI+/- No. Rate CI+/- No. Rate CI+/ , , , , , , , , , , , , * Includes any unknowns. NOTES: Age-adjusted rates are per 1, and are computed by the direct method using the 197 U.S. standard million population. Rates based on less than 2 events are considered statistically unreliable. The value of CI+/- added to and subtracted from the age-adjusted rate = 95% confidence interval. The value of CI+/- was calculated using a formula for estimating the standard error or SE (see Technical Notes). 25 FIGURE 18-A Age-Adjusted Incidence Rates by Sex and Race Pennsylvania Residents, Rate per 1, Year Pennsylvania Department of Health - Pennsylvania Cancer Incidence and Mortality Page 157

3 Cancer of the Kidney and Renal Pelvis: INCIDENCE TABLE 18-B Average Annual Age-Specific Incidence Rates by Sex and Race Age Group All Cases All Races White Black All Races White Black Total Under NOTE: Rates are per 1, population ( ) for each specified group. FIGURE 18-B Average Annual Age-Specific Incidence Rates by Sex and Race 1 8 RATE PER 1, Under AGE GROUP 85+ Pennsylvania Department of Health - Pennsylvania Cancer Incidence and Mortality Page 158

4 Cancer of the Kidney and Renal Pelvis: INCIDENCE TABLE 18-C Total Number of Cancer Cases by Age, Sex and Race Age Group All Cases* All Races* White Black All Races* White Black Total 7,959 4,83 4, ,156 2, Under , , , * Includes any unknowns. FIGURE 18-C Stage of Disease at Diagnosis, Percent by Sex and Race Pennsylvania Residents, In Situ Local Regional Distant Percent Number and Percent of Cases Microscopically Confirmed: 1, % Pennsylvania Department of Health - Pennsylvania Cancer Incidence and Mortality Page 159

5 Cancer of the Kidney and Renal Pelvis: MORTALITY TABLE 18-D Number of Deaths, Age-Adjusted Death Rates and Range for 95% Confidence Intervals by Sex, Race and Year, Pennsylvania Residents, All Deaths* All Races* White Black All Races* White Black Year No. Rate CI+/- No. Rate CI+/- No. Rate CI+/- No. Rate CI+/- No. Rate CI+/- No. Rate CI+/- No. Rate CI+/ * Includes any unknowns. NOTES: Age-adjusted rates are per 1, and are computed by the direct method using the 197 U.S. standard million population. Rates based on less than 2 events are considered statistically unreliable. The value of CI+/- added to and subtracted from the age-adjusted rate = 95% confidence interval. The value of CI+/- was calculated using a formula for estimating the standard error or SE (see Technical Notes). 1 FIGURE 18-D Age-Adjusted Death Rates by Sex and Race Pennsylvania Residents, Rate per 1, Year Pennsylvania Department of Health - Pennsylvania Cancer Incidence and Mortality Page 16

6 Cancer of the Kidney and Renal Pelvis: MORTALITY TABLE 18-E Number of Deaths and Average Annual Age-Specific Death Rates by Sex and Race All Deaths* All Races* White Black All Races* White Black Age Group No. Rate No. Rate No. Rate No. Rate No. Rate No. Rate No. Rate Total* 2, , , , , Under * Includes any unknowns. NOTE: Rates are per 1, population ( ) for each specified group. FIGURE 18-E Average Annual Age-Specific Death Rates by Sex and Race 8 6 Rate per 1, 4 2 Under Age Group Pennsylvania Department of Health - Pennsylvania Cancer Incidence and Mortality Page 161

7 Cancer of the Kidney and Renal Pelvis: INCIDENCE TABLE 18-F Number of Cases, Average Annual Age-Adjusted Incidence Rates and Range for 95% Confidence Intervals by County and Sex, Total Total County Cases No. Rate CI+/- No. Rate CI+/- County Cases No. Rate CI+/- No. Rate CI+/- All Counties 7,959 4, , Adams Juniata Allegheny Lackawanna Armstrong Lancaster Beaver Lawrence Bedford Lebanon Berks Lehigh Blair Luzerne Bradford Lycoming Bucks McKean Butler Mercer Cambria Mifflin Cameron Monroe Carbon Montgomery Centre Montour Chester Northampton Clarion Northumberland Clearfield Perry Clinton Philadelphia 1, Columbia Pike Crawford Potter Cumberland Schuylkill Dauphin Snyder Delaware Somerset Elk Sullivan Erie Susquehanna Fayette Tioga Forest Union Franklin Venango Fulton Warren Greene Washington Huntingdon Wayne Indiana Westmoreland Jefferson Wyoming York NOTES: Age-adjusted rates are per 1, and are computed by the direct method using the 197 U.S. standard million population. Rates based on less than 2 events are considered statistically unreliable. The value of CI+/- added to and subtracted from the age-adjusted rate = 95% confidence interval. The value of CI+/- was calculated using a formula for estimating the standard error or SE (see Technical Notes). Pennsylvania Department of Health - Pennsylvania Cancer Incidence and Mortality Page 162

8 Cancer of the Kidney and Renal Pelvis: MORTALITY TABLE 18-G Number of Deaths, Average Annual Age-Adjusted Death Rates and Range for 95% Confidence Intervals By County and Sex, Total Total County Deaths No. Rate CI+/- No. Rate CI+/- County Deaths No. Rate CI+/- No. Rate CI+/- All Counties 2,963 1, , Adams Juniata Allegheny Lackawanna Armstrong Lancaster Beaver Lawrence Bedford Lebanon Berks Lehigh Blair Luzerne Bradford Lycoming Bucks McKean Butler Mercer Cambria Mifflin Cameron Monroe Carbon Montgomery Centre Montour Chester Northampton Clarion Northumberland Clearfield Perry Clinton Philadelphia Columbia Pike Crawford Potter Cumberland Schuylkill Dauphin Snyder Delaware Somerset Elk Sullivan Erie Susquehanna Fayette Tioga Forest Union Franklin Venango Fulton Warren Greene Washington Huntingdon Wayne Indiana Westmoreland Jefferson Wyoming York NOTES: Age-adjusted rates are per 1, and are computed by the direct method using the 197 U.S. standard million population. Rates based on less than 2 events are considered statistically unreliable. The value of CI+/- added to and subtracted from the age-adjusted rate = 95% confidence interval. The value of CI+/- was calculated using a formula for estimating the standard error or SE (see Technical Notes). Pennsylvania Department of Health - Pennsylvania Cancer Incidence and Mortality Page 163

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