List of nationally authorised medicinal products

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1 8 February 2018 EMA/88406/2018 Human Medicines Evaluation Division Active substance: benserazide / levodopa Procedure no.: PSUSA/ / Churchill Place Canary Wharf London E14 5EU United Kingdom Telephone +44 (0) Facsimile +44 (0) Send a question via our website An agency of the European Union European Medicines Agency, Reproduction is authorised provided the source is acknowledged.

2 Madopar "125" not available 6366 ROCHE A/S DK Madopar "125" not available ROCHE A/S DK Madopar 125 hörð hylki not available ROCHE A/S IS Madopar 125 töflur not available ROCHE A/S IS Madopar 250 töflur not available ROCHE A/S IS Madopar 250 hörð hylki not available ROCHE A/S IS Madopar 62,5 hörð not available ROCHE A/S IS hylki Madopar 100 mg + 25 not available ROCHE S.P.A. IT mg capsule rigide Madopar 100 mg + 25 not available ROCHE S.P.A. IT mg capsule rigide a rilascio prolungato Madopar 100 mg + 25 not available ROCHE S.P.A. IT mg compresse dispersibili Madopar 100 mg/25 mg not available ROCHE AUSTRIA GMBH AT - lösliche Tabletten Madopar 100 mg/25 mg not available ROCHE AUSTRIA GMBH AT - Tabletten Madopar 100 mg/25 mg not available ROCHE LATVIJA SIA LV cietās kapsulas Madopar 100 mg/25 mg not available 9882 ROCHE OY FI depotkapslar Madopar 100 mg/25 mg not available ROCHE EESTI OÜ EE dispergeeruvad tabletid Madopar 100 mg/25 mg not available ROCHE LATVIJA SIA LV disperģējamās tabletes Madopar 100 mg/25 mg not available LT/1/94/0936/002 UAB "ROCHE LIETUVA" LT disperguojamosios tabletės Madopar 100 mg/25 mg Dispersible Tablets not available PL 00031/0221 ROCHE PRODUCTS LTD UK Madopar 100 mg/25 mg disperzibilne tablete not available H/96/00958/001 ROCHE FARMACEVTSKA DRUŽBA D.O.O. SI EMA/88406/2018 Page 2/12

3 Madopar 100 mg/25 mg not available OGYI-T-1157/02 ROCHE (MAGYARORSZÁG) HU diszpergálódó tabletta KFT Madopar 100 mg/25 mg not available MA060/00603 ROCHE PRODUCTS LTD MT Madopar 100 mg/25 mg not available PL 00031/0073 ROCHE PRODUCTS LTD UK Madopar 100 mg/25 mg not available LT/1/94/0936/003 UAB "ROCHE LIETUVA" LT kietosios kapsulės Madopar 100 mg/25 mg not available ROCHE EESTI OÜ EE kõvakapslid Madopar 100 mg/25 mg not available OGYI-T-1157/03 ROCHE (MAGYARORSZÁG) HU retard kemény kapszula KFT Madopar 100 mg/25 mg not available H/96/00958/002 ROCHE FARMACEVTSKA SI tablete DRUŽBA D.O.O. Madopar 100 mg/25 mg not available 9672 ROCHE OY FI tabletter Madopar 100mg/25mg not available PA 50/43/6 ROCHE PRODUCTS LTD IE Dispersible Tablets Madopar 12,5/50 not available 6694 F. HOFFMANN-LA ROCHE AG NO kapsler, harde Madopar 125 mg, 100 not available R/0950 ROCHE POLSKA SP.O.O. PL mg + 25 mg, kapsułki Madopar 125 mg, 100 not available 7487 ROCHE POLSKA SP.O.O. PL mg + 25 mg, tabletki do sporządzania zawiesiny doustnej Madopar 125 mg, not available RVG ROCHE NEDERLAND B.V. NL dispergeerbare tabletten Madopar 125 mg, not available RVG ROCHE NEDERLAND B.V. NL tabletten Madopar 125 tablete not available HR-H ROCHE D.O.O. HR Madopar 200 mg + 50 mg compresse divisibili not available ROCHE S.P.A. IT EMA/88406/2018 Page 3/12

4 Madopar 200 mg + 50 mg comprimidos Madopar 200 mg + 50 mg comprimidos - Tabletten comprimate tablete tabletes tabletės tabletid tabletta tabletter Madopar 200mg/50mg Madopar 25/100 kapsler, harde Madopar 250 kapsler, hårde Madopar 250 mg, 200 mg + 50 mg, tabletki Madopar 250 mg, tabletten not available ROCHE FARMACÊUTICA QUÍMICA, LDA. PT not available ROCHE FARMACÊUTICA PT QUÍMICA, LDA. not available ROCHE AUSTRIA GMBH AT not available 8133/2006/01 ROCHE ROMANIA SRL RO not available MA060/00604 ROCHE PRODUCTS LTD MT not available PL 00031/0074 ROCHE PRODUCTS LTD UK not available H/96/00958/003 ROCHE FARMACEVTSKA SI DRUŽBA D.O.O. not available ROCHE LATVIJA SIA LV not available LT/1/94/0936/001 UAB "ROCHE LIETUVA" LT not available ROCHE EESTI OÜ EE not available OGYI-T-1157/01 ROCHE (MAGYARORSZÁG) HU KFT not available 8611 ROCHE OY FI not available PA 50/43/2 ROCHE PRODUCTS LTD IE not available 5967 F. HOFFMANN-LA ROCHE AG NO not available 6367 ROCHE A/S DK not available R/0951 ROCHE POLSKA SP.O.O. PL not available RVG ROCHE NEDERLAND B.V. NL EMA/88406/2018 Page 4/12

5 Madopar 250 tablety not available 27/391/01-C ROCHE S. R. O. CZ Madopar 250, tabletter not available ROCHE A/S DK Madopar 50 mg/12,5 mg not available ROCHE AUSTRIA GMBH AT - Kapseln Madopar 50 mg/12.5 mg not available PL 00031/0220 ROCHE PRODUCTS LTD UK Dispersible Tablets Madopar 50 mg/12.5 mg not available MA060/00602 ROCHE PRODUCTS LTD MT Madopar 50 mg/12.5 mg not available PL 00031/0125 ROCHE PRODUCTS LTD UK Madopar 50mg/12.5mg not available PA 50/43/5 ROCHE PRODUCTS LTD IE Dispersible Tablets Madopar 62,5 kapsler, not available 9821 ROCHE A/S DK hårde Madopar 62,5 mg, 50 mg not available R/0949 ROCHE POLSKA SP.O.O. PL + 12,5 mg, kapsułki Madopar 62,5 mg, 50 mg not available 7486 ROCHE POLSKA SP.O.O. PL + 12,5 mg, tabletki do sporządzania zawiesiny doustnej Madopar 62,5 mg, not available RVG ROCHE NEDERLAND B.V. NL capsules Madopar 62,5 rozpustné not available 27/029/04-C ROCHE S. R. O. CZ tablety Madopar CR 100 mg/25 not available ROCHE AUSTRIA GMBH AT mg - Kapseln Madopar CR 100 mg/25 not available MA060/00601 ROCHE PRODUCTS LTD MT mg Prolonged Release Madopar CR 100 mg/25 not available PL 00031/0227 ROCHE PRODUCTS LTD UK mg Prolonged Release Madopar DEPOT 100 mg/25 mg hörð forðahylki not available ROCHE A/S IS EMA/88406/2018 Page 5/12

6 Madopar Depot 25/100 depotkapsler Madopar DEPOT, depotkapsler, hårde Madopar Dispersible 125 mg dispergovateľné tablety Madopar HBS 100 mg + 25 mg cápsulas de libertação prolongada Madopar HBS 100 mg/25 mg ilgstošās darbības cietās kapsulas Madopar HBS 100 mg/25 mg pailginto atpalaidavimo kietosios kapsulės Madopar HBS 100 mg/25 mg toimeainet prolongeeritult vabastavad kõvakapslid Madopar HBS 125 mg, capsules met gereguleerde afgifte Madopar HBS 125 mgtvrdé kapsuly s riadeným uvolnovaním Madopar HBS capsule cu eliberare modificată Madopar HBS capsule cu eliberare modificată Madopar HBS tvrdé tobolky s řízeným uvolňováním not available 7430 F. HOFFMANN-LA ROCHE AG NO not available ROCHE A/S DK not available 27/0156/00-S ROCHE SLOVENSKO S.R.O. SK not available ROCHE FARMACÊUTICA QUÍMICA, LDA. not available ROCHE LATVIJA SIA LV not available LT/1/94/0936/004 UAB "ROCHE LIETUVA" LT not available ROCHE EESTI OÜ EE not available RVG ROCHE NEDERLAND B.V. NL not available 27/0168/89-C/S ROCHE SLOVENSKO S.R.O. SK not available 7678/2006/01 ROCHE ROMANIA SRL RO not available 7678/2006/02 ROCHE ROMANIA SRL RO not available 27/168/89-C ROCHE S. R. O. CZ PT EMA/88406/2018 Page 6/12

7 Madopar HBS, 100 mg + not available R/3775 ROCHE POLSKA SP.O.O. PL 25 mg, kapsułki Madopar Quick "125" not available ROCHE A/S DK Madopar Quick "62,5" not available ROCHE A/S DK Madopar Quick 62,5 not available ROCHE A/S IS lausnartöflur Madopar QUICK 100 not available ROCHE OY FI mg/25 mg lösliga tabletter Madopar Quick 125 not available ROCHE A/S IS lausnartöflur Madopar RETARD 100/25 not available ROCHE FARMA, S.A. ES mg cápsulas duras de liberación prolongada Madopar Solubile not available 8052 F. HOFFMANN-LA ROCHE AG NO 12,5/50 oppløselige tabletter Madopar, 200 mg + 50 not available R/0952 ROCHE POLSKA SP.O.O. PL mg, kapsułki Madopar not available 85847/15/ ROCHE (HELLAS) SA GR MADOPAR 100 mg/25 not available 9882 ROCHE OY FI mg depotkapseli MADOPAR 100 mg/25 not available 9672 ROCHE OY FI mg tabletti Madopar 125 mg not available ROCHE PHARMA AG DE Hartkapseln Madopar 125 mg T not available ROCHE PHARMA AG DE Tabletten MADOPAR not available 8611 ROCHE OY FI 200 mg/50 mg tabletti Madopar 250 not available ROCHE FARMA S.A. ES EMA/88406/2018 Page 7/12

8 Madopar 250 mg Tabletten Levodopa 200 mg Benserazid 50 mg (als Benserazidhydrochlorid) Madopar 62,5 mg Hartkapseln Levodopa 50 mg Benserazid 12,5 mg (als Benserazidhydrochlorid) Madopar Depot Hartkapseln, retardiert Levodopa 100 mg Benserazid 25 mg (als Benserazidhydrochlorid) Madopar LT Tabletten zur Herstellung einer Suspension zum Einnehmen Levodopa 100 mg Benserazid 25 mg (als Benserazidhydrochlorid) MADOPAR QUICK 100 mg/25 mg liukeneva tabletti Madopark 100 mg/25 mg tabletter Madopark DEPOT 100 mg/25 mg depotkapslar, hårda Madopark Quick 100 mg/25 mg tabletter Madopark Quick mite 50 mg/12,5 mg tabletter not available ROCHE PHARMA AG DE not available ROCHE PHARMA AG DE not available ROCHE PHARMA AG DE not available ROCHE PHARMA AG DE not available ROCHE OY FI not available ROCHE AB SE not available ROCHE AB SE not available ROCHE AB SE not available ROCHE AB SE EMA/88406/2018 Page 8/12

9 Maдопар 100 mg/25 mg диспергиращи се таблетки Maдопар 200 mg/50 mg таблетки Modopar 125 (100 mg/25 mg), gélule Modopar 125 (100 mg/25 mg), gélule Modopar 125 (100 mg/25 mg), gélule Modopar 125 (100 mg/25 mg), gélule Modopar 125 (100 mg/25 mg), gélule Modopar 125 (100 mg/25 mg), gélule MODOPAR 125 DISPERSIBLE (100 mg/25 mg), comprimé sécable pour suspension buvable MODOPAR 125 DISPERSIBLE (100 mg/25 mg), comprimé sécable pour suspension buvable Modopar 250 (200 mg/50 mg), gélule Modopar 250 (200 mg/50 mg), gélule Modopar 250 (200 mg/50 mg), gélule Modopar 250 (200 mg/50 mg), gélule not available ROCHE BULGARIA EOOD BG not available ROCHE BULGARIA EOOD BG not available ROCHE FR not available ROCHE FR not available ROCHE FR not available ROCHE FR not available ROCHE FR not available ROCHE FR not available ROCHE FR not available ROCHE FR not available ROCHE FR not available ROCHE FR not available ROCHE FR not available ROCHE FR EMA/88406/2018 Page 9/12

10 Modopar 250 (200 mg/50 mg), gélule Modopar 250 (200 mg/50 mg), gélule Modopar 62,5 (50 mg/12,5 mg), gélule Modopar 62,5 (50 mg/12,5 mg), gélule Modopar L.P. 125 (100 mg/25 mg), gélule a liberation prolongee Modopar L.P. 125 (100 mg/25 mg), gélule a liberation prolongee Modopar L.P. 125 (100 mg/25 mg), gélule a liberation prolongee MODOPAR L.P mg/25 mg, gélule à libération prolongée MODOPAR L.P mg/25 mg, gélule à libération prolongée MODOPAR L.P mg/25 mg, gélule à libération prolongée Prolopa 125, 100 mg/25 mg, capsules, hard Prolopa 125, 100 mg/25 mg, comprimés dispersibles Prolopa 125, 100 mg/25 mg, comprimés dispersibles not available ROCHE FR not available ROCHE FR not available ROCHE FR not available ROCHE FR not available ROCHE FR not available ROCHE FR not available ROCHE FR not available ROCHE FR not available ROCHE FR not available ROCHE FR not available BE N.V. ROCHE S.A. BE not available BE N.V. ROCHE S.A. BE not available 0178/ N.V. ROCHE S.A. LU EMA/88406/2018 Page 10/12

11 Prolopa 125, 100 mg/25 not available BE N.V. ROCHE S.A. BE mg, dispergeerbare tabletten Prolopa 125, 100 mg/25 not available BE N.V. ROCHE S.A. BE mg, gélules Prolopa 125, 100 mg/25 not available 0178/ N.V. ROCHE S.A. LU mg, gélules Prolopa 125, 100 mg/25 not available BE N.V. ROCHE S.A. BE mg, Hartkapseln Prolopa 125, 100 mg/25 not available 0178/ N.V. ROCHE S.A. LU mg, Hartkapseln Prolopa 125, 100 mg/25 not available BE N.V. ROCHE S.A. BE mg, Tabletten zur Herstellung einer Suspension zum Einnehmen Prolopa 125, 100 mg/25 not available 0178/ N.V. ROCHE S.A. LU mg, Tabletten zur Herstellung einer Suspension zum Einnehmen Prolopa 250 comprimés not available 0178/ N.V. ROCHE S.A. LU Prolopa 250, 200 mg/50 not available BE N.V. ROCHE S.A. BE mg, comprimés Prolopa 250, 200 mg/50 not available BE N.V. ROCHE S.A. BE mg, tabletten Prolopa 250, 200 mg/50 not available BE N.V. ROCHE S.A. BE mg, Tabletten Prolopa 250, 200 mg/50 not available 0178/ N.V. ROCHE S.A. LU mg, Tabletten Prolopa HBS 125, 100 mg/25 mg, capsules met verlengde afgifte, hard not available BE N.V. ROCHE S.A. BE EMA/88406/2018 Page 11/12

12 Prolopa HBS 125, 100 mg/25 mg, gélules à libération prolongée Prolopa HBS 125, 100 mg/25 mg, gélules à libération prolongée Prolopa HBS 125, 100 mg/25 mg, Hartkapseln, retardiert Prolopa HBS 125, 100 mg/25 mg, Hartkapseln, retardiert RESTEX 100 mg/25 mg Retardkapseln RESTEX 100 mg/25 mg Tabletten Restex 100 mg/25 mg Tabletten Restex 100 mg/25 mg Hartkapseln, retardiert Мадопар HBS 100 mg/25 mg твърди капсули с удължено освобождаване not available BE N.V. ROCHE S.A. BE not available 0178/ N.V. ROCHE S.A. LU not available BE N.V. ROCHE S.A. BE not available 0178/ N.V. ROCHE S.A. LU DE/H/0371/ ROCHE AUSTRIA GMBH AT DE/H/0371/ ROCHE AUSTRIA GMBH AT DE/H/0371/ ROCHE PHARMA AG DE DE/H/0371/ ROCHE PHARMA AG DE not available ROCHE BULGARIA EOOD BG EMA/88406/2018 Page 12/12

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