GKF HiProTect True Containment Capsule Filling. Packaging Technology
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1 GKF HiProTect True Containment Capsule Filling Packaging Technology
2 Wide Range of Filling Combinations Weighing The GKF HiProTect employs a modular machine design for 3 stages of check weighing. One station is the statistical gross weight control to determine the weight of a filled capsule. In combination with the second weight control for empty capsules you get a statistical value of the net filling weight. Another option is an integrated 100 % capsule control that means every fill weight will be determined online. The weighing station provides automatic feedback to the dosing station. The filling unit can then be automatically adjusted to fill the product within the defined tolerances. The 100% capsule control unit ensures real time quality control, resulting in a constantly controlled process for high product quality. Filling The GKF HiProTect is suitable for a wide range of filling options, such as powder, tablets, pellets, liquids and combination filling. The modular design concept also accommodates for future production needs by allowing additional filling stations to be easily integrated later. The flexibility of a large variety of filling combinations enables production to respond to changing market demands and ensures a long-term costeffective investment. All of the filling stations are based on the proven technology from the standard GKF line with improvements to meet the requirements for containment and automatic cleaning. Powder The filling station with the patented slide gate principle ensures minimum product waste and maximum filling accuracy. The innovative design of the filling unit sets a new standard in filling efficiency. With a microdosing kit, the design also makes it possible to fill products at weights less than 2 mg. Pellets Pellet filling and powder filling can be accomplished with the same station, offering a high degree of flexibility and avoiding the need for additional filling equipment. The design focuses on smooth pellet handling and the highest filling precision. Tablets A tablet counting station can be integrated for high accuracy tablet dispensing. This proven solution is well known as a gentle and accurate filling unit. Liquids Liquid filling is based on the proven technology of the GKF 1400L and can process a wide range of liquid viscosity levels from oils to pastes. The ability to adjust individual parameters makes it possible to have the best filling results. Automatic Cleaning System Product or batch changes usually require a cleaning process. The GKF HiProTect has an integrated cleaning system to maintain the level of operator protection during this process step. A principle philosophy used in the design was to avoid unnecessary product waste. The no cap/no fill function prevents contamination inside the production environment. The filling unit will only dose the product when a complete empty capsule is present. Several spray nozzles, which move inside the machine during the cleaning cycle, clean every square inch with desalinated water, acids, or caustic cleaning solutions. A programmable washing system stores and recalls cleaning protocols, guaranteeing a reproducible cleaning result for your individual wash-in-place or clean-in-place process. The GKF employs 316L stainless steel and FDA-approved plastics in compliance with industry standards.
3 GKF HiProTect True Containment Capsule Filling The GKF HiProTect is a capsule filling machine with containment for processing potent substances. This system answers the growing need for pharmaceutical researchers and manufacturers to be completely isolated from active substances during operation, maintenance, and cleaning. The GKF HiProTect does this through an array of automated processes and provides a true containment solution. The GKF HiProTect is designed to provide easy accessibility to all stations, making it simple to interact with the machine components inside the contained area. The machine is upgradeable and additional stations can be easily added to accommodate future production needs making it adaptable to exact customer applications. Containment system to process highly potent pharmaceutical products Modular design provides filling flexibility for specific applications Automated cleaning system provides consistency and ensures operator safety Integrated weighing concept for real time quality control
4 A Total System Supplier for All Your Containment Needs Bosch can integrate the needed equipment to provide a complete line solution. This means integrating components such as a contained capsule polisher with metal detector, an air management system, a WIP center to supply cleaning materials, or any other components that the system may need. An automated remote monitoring system also offers lights out operation capabilities, providing manufacturers with high productivity Containment system meets the trend towards high protency pharmaceuticals Modular design provides flexibility to customize equipment applications Automated cleaning system reduces downtime
5 We are Your Containment Specialists For nearly 40 years, Bosch Packaging Technology has been an innovative force in the global pharmaceutical industry. From packaging to processing, we offer the industry highly flexible, modular systems as well as the expertise to enable customers to grow and succeed in a competitive market. Bosch A recognized supplier of isolator technology for many years GKF HiProTect A capsule filling machine specifically designed for handling highly active substances GKF HiProTect Capsule filling and integrated checkweighing in one innovative platform. With the growth of highly potent applications in the pharmaceutical and biopharmaceutical industries, containment is increasingly necessary to reduce contact between humans and the production process. As a longtime supplier for isolator technology, we can also offer capsule filling machines which meet the requirements for containment. Our system reduces operator exposure by providing the required OEL OEL 5 < 1μg/m 3 2 1
6 Robert Bosch GmbH Packaging Technology Product Division Pharma Solid Stuttgarter Straße Waiblingen Germany Phone PA-PH % chlorine free paper All rights reserved
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