SECTION 1: Identification of the substance/mixture and of the company/undertaking

Transcription

1 Safety data sheet Page: 1/159 SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Product identifier Lorol C Chemical name: Dodecanol-1 REACH registration number: , Relevant identified uses of the substance or mixture and uses advised against Relevant identified uses: Oleochemical raw material For the detailed identified uses of the product see appendix of the safety data sheet Details of the supplier of the safety data sheet Company: BASF SE Ludwigshafen GERMANY Contact address: BASF plc PO Box 4, Earl Road, Cheadle Hulme, Cheadle, Cheshire SK8 6QG, UNITED KINGDOM Telephone: address: product-safety-north@basf.com 1.4. Emergency telephone number International emergency number: Telephone: SECTION 2: Hazards Identification

2 Page: 2/ Classification of the substance or mixture According to Regulation (EC) No 1272/2008 [CLP] Eye Dam./Irrit. 2 Aquatic Acute 1 Aquatic Chronic 2 H319, H411, H400 For the classifications not written out in full in this section the full text can be found in section Label elements According to Regulation (EC) No 1272/2008 [CLP] Pictogram: Signal Word: Warning Hazard Statement: H319 H411 H400 Causes serious eye irritation. Toxic to aquatic life with long lasting effects. Very toxic to aquatic life. Precautionary Statements (Prevention): P273 Avoid release to the environment. P280 Wear eye/face protection. P264 Wash with plenty of water and soap thoroughly after handling. Precautionary Statements (Response): P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P391 Collect spillage. P337 + P311 If eye irritation persists: Call a POISON CENTER or doctor/physician. Precautionary Statements (Disposal): P501 Dispose of contents/container to hazardous or special waste collection point Other hazards According to Regulation (EC) No 1272/2008 [CLP]

3 Page: 3/159 No specific dangers known, if the regulations/notes for storage and handling are considered. SECTION 3: Composition/Information on Ingredients 3.1. Substances Chemical nature CAS Number: EC-Number: For the classifications not written out in full in this section, including the hazard classes and the hazard statements, the full text is listed in section Mixtures Not applicable SECTION 4: First-Aid Measures 4.1. Description of first aid measures If adverse health effects develop seek medical attention. If inhaled: not relevant. On skin contact: After contact with skin, wash immediately with plenty of water. On contact with eyes: In case of contact with the eyes, rinse immediately for at least 15 minutes with plenty of water. Seek medical attention if necessary. On ingestion: Rinse mouth and then drink ml of water Most important symptoms and effects, both acute and delayed Symptoms: The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11., Further important symptoms and effects are so far not known. Hazards: No hazard is expected under intended use and appropriate handling.

4 Page: 4/ Indication of any immediate medical attention and special treatment needed Treatment: Treat symptomatically. SECTION 5: Fire-Fighting Measures 5.1. Extinguishing media Suitable extinguishing media: water spray, carbon dioxide, dry powder, foam 5.2. Special hazards arising from the substance or mixture harmful vapours Evolution of fumes/fog. The substances/groups of substances mentioned can be released in case of fire Advice for fire-fighters Further information: Dispose of fire debris and contaminated extinguishing water in accordance with official regulations. SECTION 6: Accidental Release Measures 6.1. Personal precautions, protective equipment and emergency procedures Use personal protective clothing Environmental precautions Do not discharge into drains/surface waters/groundwater Methods and material for containment and cleaning up For small amounts: Pick up with suitable absorbent material. For large amounts: Dike spillage. Pump off product. Dispose of absorbed material in accordance with regulations Reference to other sections Information regarding exposure controls/personal protection and disposal considerations can be found in section 8 and 13. SECTION 7: Handling and Storage 7.1. Precautions for safe handling Handle in accordance with good industrial hygiene and safety practice. Protection against fire and explosion: Take precautionary measures against static discharges. Avoid all sources of ignition: heat, sparks, open flame Conditions for safe storage, including any incompatibilities Suitable materials for containers: High density polyethylene (HDPE)

5 Page: 5/159 Further information on storage conditions: Keep container tightly closed and dry; store in a cool place. Storage stability: Storage temperature: >= 25 C 7.3. Specific end use(s) For the relevant identified use(s) listed in Section 1 the advice mentioned in this section 7 is to be observed. SECTION 8: Exposure Controls/Personal Protection 8.1. Control parameters Components with occupational exposure limits No occupational exposure limits known. PNEC Data refer to the product Components with PNEC : freshwater: mg/l marine water: mg/l intermittent release: No PNEC value available. STP: mg/l sediment (freshwater): 1.1 mg/kg sediment (marine water): 0.11 mg/kg soil: mg/kg oral (secondary poisoning): No PNEC value available. DNEL Data refer to the product Components with DNEL : worker: Short-term exposure - systemic effects, dermal: 125 mg/kg worker: Short-term exposure - systemic effects, Inhalation: 220 mg/m3 worker: Long-term exposure- systemic effects, dermal: 125 mg/kg worker: Long-term exposure- systemic effects, Inhalation: 220 mg/m3 consumer: Short-term exposure - systemic effects, dermal: 75 mg/kg consumer: Short-term exposure - systemic effects, Inhalation: 65 mg/m3 consumer: Short-term exposure - systemic effects, oral: 75 mg/kg consumer: Long-term exposure- systemic effects, dermal: 75 mg/kg

6 Page: 6/159 consumer: Long-term exposure- systemic effects, Inhalation: 65 mg/m3 consumer: Long-term exposure- systemic effects, oral: 75 mg/kg 8.2. Exposure controls Personal protective equipment Respiratory protection: Respiratory protection not required. Hand protection: Hand protection not required. Eye protection: Safety glasses with side-shields (frame goggles) (e.g. EN 166) Body protection: Body protection must be chosen depending on activity and possible exposure, e.g. apron, protecting boots, chemical-protection suit (according to EN in case of splashes or EN ISO in case of dust). General safety and hygiene measures Handle in accordance with good industrial hygiene and safety practice. No eating, drinking, smoking or tobacco use at the place of work. Handle in accordance with good industrial hygiene and safety practice. Environmental exposure controls For information regarding environmental exposure controls, see Section 6. SECTION 9: Physical and Chemical Properties 9.1. Information on basic physical and chemical properties Form: liquid Colour: colourless Odour: nutty Odour threshold: not applicable ph value: not applicable freezing range: C (DIN ISO 3841) Boiling range: C (DIN 51751) Flash point: C (DIN EN 22719; ISO 2719) Evaporation rate: Value can be approximated from Henry's Law Constant or vapor pressure. Flammability: not flammable Flammability of Aerosol Products: not applicable, the product does not form flammable aerosoles

7 Page: 7/159 Lower explosion limit: For liquids not relevant for classification and labelling. Upper explosion limit: For liquids not relevant for classification and labelling. Ignition temperature: 275 C Vapour pressure: not determined Density: g/cm3 (DIN 51757) (30 C) g/cm3 (55 C) (DIN 51757) Relative vapour density (air): not applicable Solubility in water: insoluble Solubility (qualitative) solvent(s): distilled water insoluble Partitioning coefficient n-octanol/water (log Kow): 5.4 (OECD Guideline 117) Self ignition: Temperature: 275 C Thermal decomposition: No decomposition if stored and handled as prescribed/indicated. Viscosity, dynamic: mpa*s (ASTM D ) Viscosity, kinematic: not determined Explosion hazard: not explosive Fire promoting properties: not fire-propagating 9.2. Other information Other Information: If necessary, information on other physical and chemical parameters is indicated in this section. No further information available. SECTION 10: Stability and Reactivity Reactivity No hazardous reactions if stored and handled as prescribed/indicated Chemical stability The product is stable if stored and handled as prescribed/indicated Possibility of hazardous reactions None if used for intended purpose Conditions to avoid See MSDS section 7 - Handling and storage.

8 Page: 8/ Incompatible materials Substances to avoid: No substances known that should be avoided Hazardous decomposition products Hazardous decomposition products: No hazardous decomposition products known. SECTION 11: Toxicological Information Information on toxicological effects Acute toxicity Assessment of acute toxicity: Virtually nontoxic after a single ingestion. Experimental/calculated data: LD50 rat (oral): > 5,000 mg/kg (OECD Guideline 401) Irritation Assessment of irritating effects: Eye contact causes irritation. Not irritating to the skin. Experimental/calculated data: Skin corrosion/irritation human: non-irritant (Human patch test) Serious eye damage/irritation rabbit: Irritant. (OECD Guideline 405) Respiratory/Skin sensitization Assessment of sensitization: No sensitizing effect. Experimental/calculated data: Guinea pig maximization test guinea pig: Non-sensitizing. (OECD Guideline 406) Germ cell mutagenicity Assessment of mutagenicity: Results from a number of mutagenicity studies with microorganisms, mammalian cell culture and mammals are available. Taking into account all of the information, there is no indication that the substance is mutagenic.

9 Page: 9/159 Experimental/calculated data: Ames-test Bacteria: negative (Directive 84/449/EEC, B.14) Micronucleus assay mouse: negative (OECD Guideline 474) Carcinogenicity Assessment of carcinogenicity: The whole of the information assessable provides no indication of a carcinogenic effect. Reproductive toxicity Assessment of reproduction toxicity: The information available on the product provides no indication of reproductive toxicity. Developmental toxicity Assessment of teratogenicity: No indications of a developmental toxic / teratogenic effect were seen in animal studies. Specific target organ toxicity (single exposure) Assessment of STOT single: Based on the available information there is no specific target organ toxicity to be expected after a single exposure. Repeated dose toxicity and Specific target organ toxicity (repeated exposure) Assessment of repeated dose toxicity: The information available on the product provides no indication of toxicity on target organs after repeated exposure. Aspiration hazard No aspiration hazard expected. SECTION 12: Ecological Information Toxicity Toxicity to fish: LC50 > 1-10 mg/l, Pimephales promelas (DIN EN ISO ) Aquatic invertebrates: EC50 > mg/l, Daphnia magna (OECD Guideline 202, part 1)

10 Page: 10/159 Aquatic plants: EC50 > mg/l, Desmodesmus subspicatus (OECD Guideline 201) Microorganisms/Effect on activated sludge: EC0 > 100 mg/l, Pseudomonas putida (OECD Guideline 209) Chronic toxicity to fish: No observed effect concentration <= 1 mg/l The product has not been tested. The statement has been derived from substances/products of a similar structure or composition. Chronic toxicity to aquatic invertebrates: No observed effect concentration > mg/l, Daphnia magna (OECD Guideline 211) Persistence and degradability Assessment biodegradation and elimination (H2O): Readily biodegradable (according to OECD criteria) Bioaccumulative potential Assessment bioaccumulation potential: Significant accumulation in organisms is not to be expected Mobility in soil Assessment transport between environmental compartments: Volatility: The substance will slowly evaporate into the atmosphere from the water surface. Adsorption in soil: Adsorption to solid soil phase is expected Results of PBT and vpvb assessment According to Annex XIV of Regulation (EC) No.1907/2006 concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH): The product does not contain a substance fulfilling the PBT (persistent/bioaccumulative/toxic) criteria or the vpvb (very persistent/very bioaccumulative) criteria. Self classification Other adverse effects The substance is not listed in Regulation (EC) 1005/2009 on substances that deplete the ozone layer. SECTION 13: Disposal Considerations Waste treatment methods Must be disposed of or incinerated in accordance with local regulations.

11 Page: 11/159 The UK Environmental Protection (Duty of Care) Regulations (EP) and amendments should be noted (United Kingdom). This product and any uncleaned containers must be disposed of as hazardous waste in accordance with the 2005 Hazardous Waste Regulations and amendments (United Kingdom) SECTION 14: Transport Information Land transport ADR UN number UN3082 UN proper shipping name: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S. (contains FATTY ALCOHOL C12) Transport hazard class(es): 9, EHSM Packing group: III Environmental hazards: yes Special precautions for Tunnel code: E user: RID UN number UN3082 UN proper shipping name: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S. (contains FATTY ALCOHOL C12) Transport hazard class(es): 9, EHSM Packing group: III Environmental hazards: yes Special precautions for None known user: Inland waterway transport ADN UN number UN3082 UN proper shipping name: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S. (contains FATTY ALCOHOL C12) Transport hazard class(es): 9, EHSM Packing group: III Environmental hazards: yes Special precautions for None known user: Transport in inland waterway vessel Not evaluated

12 Page: 12/159 Sea transport IMDG UN number: UN 3082 UN proper shipping name: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S. (contains FATTY ALCOHOL C12) Transport hazard class(es): 9, EHSM Packing group: III Environmental hazards: yes Marine pollutant: YES Special precautions for None known user: Air transport IATA/ICAO UN number: UN 3082 UN proper shipping name: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S. (contains FATTY ALCOHOL C12) Transport hazard class(es): 9, EHSM Packing group: III Environmental hazards: yes Special precautions for None known user: UN number See corresponding entries for UN number for the respective regulations in the tables above UN proper shipping name See corresponding entries for UN proper shipping name for the respective regulations in the tables above Transport hazard class(es) See corresponding entries for Transport hazard class(es) for the respective regulations in the tables above Packing group See corresponding entries for Packing group for the respective regulations in the tables above Environmental hazards See corresponding entries for Environmental hazards for the respective regulations in the tables above Special precautions for user

13 Page: 13/159 See corresponding entries for Special precautions for user for the respective regulations in the tables above Transport in bulk according to Annex II of MARPOL and the IBC Code Regulation: Not evaluated Shipment approved: Not evaluated Pollution name: Not evaluated Pollution category: Not evaluated Ship Type: Not evaluated Further information This product is subject to the most recent edition of "The Carriage of Dangerous Goods and Use of Transportable Pressure Equipment Regulations" and their amendments (United Kingdom). SECTION 15: Regulatory Information Safety, health and environmental regulations/legislation specific for the substance or mixture If other regulatory information applies that is not already provided elsewhere in this safety data sheet, then it is described in this subsection. The data should be considered when making any assessment under the Control of Substances Hazardous to Health Regulations (COSHH), and related guidance, for example, 'COSHH Essentials' (United Kingdom). This product may be subject to the Control of Major Accident Hazards Regulations (COMAH), and amendments if specific threshold tonnages are exceeded (United Kingdom) Chemical Safety Assessment Chemical Safety Assessment performed SECTION 16: Other Information Information on intended use: This product is of industrial quality and unless otherwise specified or agreed intended exclusively for industrial use. This includes the mentioned and recommended usage. Any other intended applications should be discussed with the manufacturer. In particular this concerns the application for products that are the object of special standards and regulations. Full text of the classifications, including the hazard classes and the hazard statements, if mentioned in section 2 or 3: Eye Dam./Irrit. Serious eye damage/eye irritation Aquatic Acute Hazardous to the aquatic environment - acute Aquatic Chronic Hazardous to the aquatic environment - chronic H319 Causes serious eye irritation. H411 Toxic to aquatic life with long lasting effects.

14 Page: 14/159 H400 Very toxic to aquatic life. If you have any queries relating to this MSDS, it's contents or any other product safety related questions, please write to the following address: The data contained in this safety data sheet are based on our current knowledge and experience and describe the product only with regard to safety requirements. This safety data sheet is neither a Certificate of Analysis (CoA) nor technical data sheet and shall not be mistaken for a specification agreement. Identified uses in this safety data sheet do neither represent an agreement on the corresponding contractual quality of the substance/mixture nor a contractually designated use. It is the responsibility of the recipient of the product to ensure any proprietary rights and existing laws and legislation are observed. Vertical lines in the left hand margin indicate an amendment from the previous version.

15 Page: 15/159 Annex: Exposure Scenarios Index 1. Formulation of mixtures (industrial, professional, consumer) SU10; ERC2; PROC1, PROC2, PROC3, PROC4, PROC5, PROC8a, PROC8b, PROC9, PROC14, PROC15 2. End use (industrial, professional) SU3, SU8; ERC6a; PROC1, PROC2, PROC3, PROC4, PROC8a, PROC8b, PROC9, PROC15 3. End use (industrial, professional) SU3; ERC5; PROC1, PROC2, PROC3, PROC4, PROC5, PROC7, PROC8a, PROC8b, PROC10, PROC13, PROC15 4. End use (industrial, professional) SU22; ERC8f; PROC1, PROC2, PROC3, PROC4, PROC5, PROC8a, PROC8b, PROC10, PROC11, PROC13, PROC15, PROC19 5. Consumer applications SU21; ERC8f; PC9a 6. End use (industrial, professional) SU3, SU15; ERC4; PROC1, PROC2, PROC3, PROC4, PROC5, PROC7, PROC8a, PROC8b, PROC9, PROC10, PROC13, PROC17, PROC18 7. End use (industrial, professional) SU22, SU15; ERC8d; PROC1, PROC2, PROC3, PROC5, PROC8a, PROC8b, PROC9, PROC10, PROC11, PROC13, PROC17, PROC18 8. End use (industrial, professional) SU2; ERC4; PROC1, PROC2, PROC3, PROC4, PROC5, PROC8a, PROC8b, PROC9, PROC16, PROC17, PROC18 9. End use (industrial, professional) SU5, SU6; ERC4; PROC1, PROC2, PROC3, PROC4, PROC7, PROC8a, PROC8b, PROC End use (industrial, professional) SU3; ERC4; PROC1, PROC2, PROC3, PROC4, PROC7, PROC8a, PROC8b, PROC9, PROC10, PROC13, PROC End use (industrial, professional) SU22; ERC8d; PROC1, PROC2, PROC3, PROC4, PROC8a, PROC8b, PROC9, PROC10, PROC11, PROC13, PROC Consumer applications SU21; ERC8d; PC Consumer applications SU21; ERC8d; PC39

16 Page: 16/ End use (industrial, professional) SU3; ERC4; PROC1, PROC2, PROC3, PROC4, PROC6, PROC7, PROC8b, PROC10, PROC13, PROC End use (industrial, professional) SU22; ERC8d; PROC1, PROC2, PROC3, PROC4, PROC6, PROC8a, PROC8b, PROC10, PROC11, PROC13, PROC14, PROC End use (industrial, professional) SU19; ERC8d; PROC7, PROC8a, PROC8b, PROC9, PROC10, PROC End use (industrial, professional) SU3; ERC3; PROC1, PROC2, PROC3, PROC4, PROC5, PROC6, PROC7, PROC8a, PROC8b, PROC9, PROC10, PROC13, PROC14, PROC15, PROC21, PROC End use (industrial, professional) SU22; ERC3; PROC1, PROC2, PROC3, PROC4, PROC5, PROC6, PROC8a, PROC8b, PROC9, PROC10, PROC11, PROC13, PROC14, PROC15, PROC21, PROC End use (industrial, professional) SU1, SU22; ERC8d; PROC1, PROC2, PROC8a, PROC8b, PROC10, PROC11, PROC Consumer applications SU21; ERC8d; PC12 * * * * * * * * * * * * * * * * 1. Short title of exposure scenario Formulation of mixtures (industrial, professional, consumer) SU10; ERC2; PROC1, PROC2, PROC3, PROC4, PROC5, PROC8a, PROC8b, PROC9, PROC14, PROC15 Control of exposure and risk management measures ERC2: Formulation of preparations Annual amount used in the EU Minimum emission days per year ,710,000 kg Emission factor air Emission factor water Emission factor soil Receive Surf. Water (Flow Rate). 0 % % 0 % 18,000 m3/d

17 Page: 17/159 Dilution factor river Dilution factor coast Risk Management Measures Type of STP Municipal STP Assumed sewage treatment plant flow (m3/d) 2,000 m3/d and reference to its source EASY TRA v3.5, ECETOC TRA v3.0, Environment Risk Characterization Ratio (RCR) Risk from environmental exposure is driven by marine water Maximum amount of safe use kg/d Risk from environmental exposure is driven by marine water. Annual amount used in the EU Minimum emission days per year 300 ERC2: Formulation of preparations 44,710,000 kg Emission factor air Emission factor water Emission factor soil Receive Surf. Water (Flow Rate). Dilution factor river Dilution factor coast 0 % % 0 % 18,000 m3/d Risk Management Measures Type of STP Assumed sewage treatment plant flow (m3/d) Municipal STP 2,000 m3/d

18 Page: 18/159 and reference to its source EASY TRA v3.5, ECETOC TRA v3.0, Environment Risk Characterization Ratio (RCR) Risk from environmental exposure is driven by marine water. 2, Maximum amount of safe use kg/d Risk from environmental exposure is driven by marine water. Annual amount used in the EU Minimum emission days per year 300 Emission factor air Emission factor water Emission factor soil Receive Surf. Water (Flow Rate). Dilution factor river Dilution factor coast ERC2: Formulation of preparations 44,710,000 kg % 0.02 % 0 % 18,000 m3/d Risk Management Measures Type of STP Municipal STP Assumed sewage treatment plant flow (m3/d) 2,000 m3/d and reference to its source EASY TRA v3.5, ECETOC TRA v3.0, Environment Risk Characterization Ratio (RCR) Risk from environmental exposure is driven by marine water. 5, Maximum amount of safe use kg/d Risk from environmental exposure is driven by marine water. ERC2: Formulation of preparations

19 Page: 19/159 Annual amount used in the EU Minimum emission days per year 300 Emission factor air Emission factor water Emission factor soil Receive Surf. Water (Flow Rate). Dilution factor river Dilution factor coast 44,710,000 kg % % 0 % 18,000 m3/d Risk Management Measures Type of STP Municipal STP Assumed sewage treatment plant flow (m3/d) 2,000 m3/d and reference to its source EASY TRA v3.5, ECETOC TRA v3.0, Environment Risk Characterization Ratio (RCR) Risk from environmental exposure is driven by marine water. 29, Maximum amount of safe use kg/d Risk from environmental exposure is driven by marine water. Annual amount used in the EU Minimum emission days per year 300 ERC2: Formulation of preparations 44,710,000 kg Emission factor air Emission factor water Emission factor soil Receive Surf. Water (Flow Rate) % 0.02 % 0 % 18,000 m3/d

20 Page: 20/159 Dilution factor river Dilution factor coast Risk Management Measures Type of STP Municipal STP Assumed sewage treatment plant flow (m3/d) 2,000 m3/d and reference to its source EASY TRA v3.5, ECETOC TRA v3.0, Environment Risk Characterization Ratio (RCR) Risk from environmental exposure is driven by marine water. 2, Maximum amount of safe use kg/d Risk from environmental exposure is driven by marine water. PROC1: Use in closed process, no likelihood of exposure. and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR)

21 Page: 21/159 PROC2: Use in closed, continuous process with occasional controlled exposure. and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC3: Use in closed batch process (synthesis or formulation).

22 Page: 22/159 and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC4: Use in batch and other process (synthesis) where opportunity for exposure arises. and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR)

23 Page: 23/159 PROC5: Mixing or blending in batch processes for formulation of preparations and articles (multistage and/or significant contact). and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC8a: Transfer of substance or preparation (charging/discharging) from/to ves-sels/large containers at non-dedicated facilities

24 Page: 24/159 and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC8b: Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at dedicated facilities and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR)

25 Page: 25/159 PROC9: Transfer of substance or preparation into small containers (dedicated filling line, including weighing). and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC14: Production of preparations or articles by tabletting, compression, extrusion, pelettisation.

26 Page: 26/159 and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC15: Use a laboratory reagent. and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) * * * * * * * * * * * * * * * *

27 Page: 27/ Short title of exposure scenario End use (industrial, professional) SU3, SU8; ERC6a; PROC1, PROC2, PROC3, PROC4, PROC8a, PROC8b, PROC9, PROC15 Control of exposure and risk management measures ERC6a: Industrial use resulting in manufacture of another substance (use of intermediates) Annual amount used in the EU Minimum emission days per year 300 Emission factor air Emission factor water Emission factor soil Receive Surf. Water (Flow Rate). Dilution factor river Dilution factor coast 270,000,000 kg 0.05 % % % 390,000 m3/d Risk Management Measures Type of STP Municipal STP Assumed sewage treatment plant flow (m3/d) 10,000 m3/d and reference to its source EASY TRA v3.5, ECETOC TRA v3.0, Environment Risk Characterization Ratio (RCR) Risk from environmental exposure is driven by marine water. 395, Maximum amount of safe use kg/d Risk from environmental exposure is driven by marine water. ERC6a: Industrial use resulting in manufacture of another substance (use of intermediates)

28 Page: 28/ ,000,000 kg Annual amount used in the EU Minimum emission days per year 200 Emission factor air Emission factor water Emission factor soil Receive Surf. Water (Flow Rate). Dilution factor river Dilution factor coast 0.05 % % % 18,000 m3/d Risk Management Measures Type of STP Municipal STP Assumed sewage treatment plant flow (m3/d) 2,000 m3/d and reference to its source EASY TRA v3.5, ECETOC TRA v3.0, Environment Risk Characterization Ratio (RCR) Risk from environmental exposure is driven by marine water. 1, Maximum amount of safe use t/d Risk from environmental exposure is driven by marine water. PROC1: Use in closed process, no likelihood of exposure. and reference to its source

29 Page: 29/ mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC2: Use in closed, continuous process with occasional controlled exposure. and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC3: Use in closed batch process (synthesis or formulation).

30 Page: 30/159 and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC4: Use in batch and other process (synthesis) where opportunity for exposure arises. and reference to its source

31 Page: 31/ mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC8a: Transfer of substance or preparation (charging/discharging) from/to ves-sels/large containers at non-dedicated facilities and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC8b: Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at dedicated facilities

32 Page: 32/159 and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC9: Transfer of substance or preparation into small containers (dedicated filling line, including weighing). and reference to its source

33 Page: 33/ mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC15: Use a laboratory reagent. and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) * * * * * * * * * * * * * * * * 3. Short title of exposure scenario End use (industrial, professional) SU3; ERC5; PROC1, PROC2, PROC3, PROC4, PROC5, PROC7, PROC8a, PROC8b, PROC10, PROC13, PROC15

34 Page: 34/159 Control of exposure and risk management measures ERC5: Industrial use resulting in inclusion into or onto a matrix Annual amount used in the EU Minimum emission days per year 40 Emission factor air Emission factor water Emission factor soil Receive Surf. Water (Flow Rate). Dilution factor river Dilution factor coast 7,800,000 kg 0.01 % 0.01 % 0.01 % 18,000 m3/d Risk Management Measures Type of STP Municipal STP Assumed sewage treatment plant flow (m3/d) 2,000 m3/d and reference to its source EASY TRA v3.5, ECETOC TRA v3.0, Environment Risk Characterization Ratio (RCR) Risk from environmental exposure is driven by marine water Maximum amount of safe use kg/d Risk from environmental exposure is driven by marine water. ERC5: Industrial use resulting in inclusion into or onto a matrix Annual amount used in the EU 7,800,000 kg Minimum emission days per year 300

35 Page: 35/ % Emission factor air Emission factor water Emission factor soil Receive Surf. Water (Flow Rate). Dilution factor river Dilution factor coast 0.03 % 0.01 % 18,000 m3/d Risk Management Measures Type of STP Municipal STP Assumed sewage treatment plant flow (m3/d) 2,000 m3/d and reference to its source EASY TRA v3.5, ECETOC TRA v3.0, Environment Risk Characterization Ratio (RCR) Risk from environmental exposure is driven by marine water Maximum amount of safe use kg/d Risk from environmental exposure is driven by marine water. PROC1: Use in closed process, no likelihood of exposure. and reference to its source

36 Page: 36/ mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC2: Use in closed, continuous process with occasional controlled exposure. and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC3: Use in closed batch process (synthesis or formulation).

37 Page: 37/159 and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC4: Use in batch and other process (synthesis) where opportunity for exposure arises. and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR)

38 Page: 38/ mg/m³ Risk Characterization Ratio (RCR) PROC5: Mixing or blending in batch processes for formulation of preparations and articles (multistage and/or significant contact). and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC7: Industrial spraying

39 Page: 39/159 Risk Management Measures Wear suitable respiratory protection. Effectiveness: 90 % and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC8a: Transfer of substance or preparation (charging/discharging) from/to ves-sels/large containers at non-dedicated facilities and reference to its source mg/kg bw/day

40 Page: 40/159 Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC8b: Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at dedicated facilities and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC10: Roller application or brushing

41 Page: 41/159 and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC13: Treatment of articles by dipping and pouring. and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR)

42 Page: 42/ mg/m³ Risk Characterization Ratio (RCR) PROC15: Use a laboratory reagent. and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) * * * * * * * * * * * * * * * * 4. Short title of exposure scenario End use (industrial, professional) SU22; ERC8f; PROC1, PROC2, PROC3, PROC4, PROC5, PROC8a, PROC8b, PROC10, PROC11, PROC13, PROC15, PROC19 Control of exposure and risk management measures ERC8f: Wide dispersive outdoor use resulting in inclusion into or onto a matrix

43 Page: 43/159 Annual amount used in the EU Minimum emission days per year 365 Emission factor air Emission factor water Emission factor soil Receive Surf. Water (Flow Rate). Dilution factor river Dilution factor coast 7,800,000 kg 0.01 % 0.01 % % 18,000 m3/d Risk Management Measures Type of STP Municipal STP Assumed sewage treatment plant flow (m3/d) 2,000 m3/d and reference to its source EASY TRA v3.5, ECETOC TRA v3.0, Environment Risk Characterization Ratio (RCR) Risk from environmental exposure is driven by marine water Maximum amount of safe use kg/d Risk from environmental exposure is driven by marine water. PROC1: Use in closed process, no likelihood of exposure. Use domain: professional

44 Page: 44/159 and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC2: Use in closed, continuous process with occasional controlled exposure. Use domain: professional and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR)

45 Page: 45/159 PROC3: Use in closed batch process (synthesis or formulation). Use domain: professional and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC4: Use in batch and other process (synthesis) where opportunity for exposure arises. Use domain: professional and reference to its source

46 Page: 46/ mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC5: Mixing or blending in batch processes for formulation of preparations and articles (multistage and/or significant contact). Use domain: professional and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC8a: Transfer of substance or preparation (charging/discharging) from/to ves-sels/large containers at

47 Page: 47/159 non-dedicated facilities Use domain: professional Risk Management Measures Local exhaust ventilation Effectiveness: 80 % and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC8b: Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at dedicated facilities Use domain: professional

48 Page: 48/159 and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC10: Roller application or brushing Use domain: professional and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC11: Non industrial spraying Use domain: professional

49 Page: 49/159 Risk Management Measures Local exhaust ventilation Effectiveness: 80 % and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC13: Treatment of articles by dipping and pouring. Use domain: professional and reference to its source

50 Page: 50/ mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC15: Use a laboratory reagent. Use domain: professional and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC19: Hand-mixing with intimate contact and only PPE available. Use domain: professional

51 Page: 51/159 Risk Management Measures Wear chemically resistant gloves in combination with basic employee Effectiveness: 90 % training. and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) Short title of exposure scenario Consumer applications SU21; ERC8f; PC9a * * * * * * * * * * * * * * * * Control of exposure and risk management measures ERC8f: Wide dispersive outdoor use resulting in inclusion into or onto a matrix Annual amount used in the EU Minimum emission days per year 365 Emission factor air 7,800,000 kg 0.01 % Emission factor water 0.01 %

52 Page: 52/159 Emission factor soil Receive Surf. Water (Flow Rate). Dilution factor river Dilution factor coast % 18,000 m3/d Risk Management Measures Type of STP Municipal STP Assumed sewage treatment plant flow (m3/d) 2,000 m3/d and reference to its source EASY TRA v3.5, ECETOC TRA v3.0, Environment Risk Characterization Ratio (RCR) Risk from environmental exposure is driven by marine water Maximum amount of safe use kg/d Risk from environmental exposure is driven by marine water. PC9a: Coatings and paints, thinners, paint removers Exposure duration: 132 min 1 uses per day Relevant for inhalative exposure estimates Temperature (Application) body weight 70 kg Uptake fraction 100 % Release duration 120 min Contact rate 30 mg/min Release area cm² Release area increases over time and reference to its source

53 Page: 53/159 EASY TRA v3.5, ConsExpo v4.1, Dermal model: constant application rate, Uptake model: Uptake fraction Consumer - dermal, long-term - systemic mg/kg bw/day Risk Characterization Ratio (RCR) The calculation is based on the internal chronic dose. EASY TRA v3.5, ConsExpo v4.1, Inhalation model: exposure to vapour - evaporation Consumer - inhalation, long-term - systemic mg/m³ Risk Characterization Ratio (RCR) The exposure calculation is based on the mean concentration on the day of exposure. For scaling see: * * * * * * * * * * * * * * * * 6. Short title of exposure scenario End use (industrial, professional) SU3, SU15; ERC4; PROC1, PROC2, PROC3, PROC4, PROC5, PROC7, PROC8a, PROC8b, PROC9, PROC10, PROC13, PROC17, PROC18 Control of exposure and risk management measures ERC4: Industrial use of processing aids in processes and products, not becoming part of articles Annual amount used in the EU Minimum emission days per year ,000 kg Emission factor air Emission factor water Emission factor soil Receive Surf. Water (Flow Rate). Dilution factor river Dilution factor coast 0 % % 0.05 % 18,000 m3/d

54 Page: 54/159 Risk Management Measures Type of STP Municipal STP Assumed sewage treatment plant flow (m3/d) 2,000 m3/d and reference to its source EASY TRA v3.5, ECETOC TRA v3.0, Environment Risk Characterization Ratio (RCR) Risk from environmental exposure is driven by marine water. 1, Maximum amount of safe use kg/d Risk from environmental exposure is driven by marine water. PROC1: Use in closed process, no likelihood of exposure. and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC2: Use in closed, continuous process with occasional controlled exposure.

55 Page: 55/159 and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC3: Use in closed batch process (synthesis or formulation). and reference to its source

56 Page: 56/ mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC4: Use in batch and other process (synthesis) where opportunity for exposure arises. Risk Management Measures Local exhaust ventilation Effectiveness: 90 % and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC5: Mixing or blending in batch processes for formulation of preparations and articles (multistage and/or significant contact).

57 Page: 57/159 and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC7: Industrial spraying Risk Management Measures Local exhaust ventilation Effectiveness: 95 % and reference to its source

58 Page: 58/ mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC8a: Transfer of substance or preparation (charging/discharging) from/to ves-sels/large containers at non-dedicated facilities and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC8b: Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at dedicated facilities

59 Page: 59/159 and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC9: Transfer of substance or preparation into small containers (dedicated filling line, including weighing). and reference to its source

60 Page: 60/ mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC10: Roller application or brushing and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC13: Treatment of articles by dipping and pouring.

61 Page: 61/159 and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC17: Lubrication at high energy conditions and in partly open process. Risk Management Measures Local exhaust ventilation Effectiveness: 90 % and reference to its source mg/kg bw/day

62 Page: 62/159 Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC18: Greasing at high energy conditions. and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) * * * * * * * * * * * * * * * * 7. Short title of exposure scenario End use (industrial, professional) SU22, SU15; ERC8d; PROC1, PROC2, PROC3, PROC5, PROC8a, PROC8b, PROC9, PROC10, PROC11, PROC13, PROC17, PROC18 Control of exposure and risk management measures

63 Page: 63/159 ERC8d: Wide dispersive outdoor use of processing aids in open systems Annual amount used in the EU Minimum emission days per year 365 Emission factor air Emission factor water Emission factor soil Receive Surf. Water (Flow Rate). Dilution factor river Dilution factor coast 130,000 kg 0 % 0.11 % 0.2 % 18,000 m3/d Risk Management Measures Type of STP Municipal STP Assumed sewage treatment plant flow (m3/d) 2,000 m3/d and reference to its source EASY TRA v3.5, ECETOC TRA v3.0, Environment Risk Characterization Ratio (RCR) Risk from environmental exposure is driven by marine water Maximum amount of safe use kg/d Risk from environmental exposure is driven by marine water. PROC1: Use in closed process, no likelihood of exposure. Use domain: professional

64 Page: 64/159 and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC2: Use in closed, continuous process with occasional controlled exposure. Use domain: professional and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR)

65 Page: 65/159 PROC3: Use in closed batch process (synthesis or formulation). Use domain: professional and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC5: Mixing or blending in batch processes for formulation of preparations and articles (multistage and/or significant contact). Use domain: professional

66 Page: 66/159 and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC8a: Transfer of substance or preparation (charging/discharging) from/to ves-sels/large containers at non-dedicated facilities Use domain: professional and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR)

67 Page: 67/159 PROC8b: Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at dedicated facilities Use domain: professional and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC9: Transfer of substance or preparation into small containers (dedicated filling line, including weighing). Use domain: professional

68 Page: 68/159 and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC10: Roller application or brushing Use domain: professional and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC11: Non industrial spraying

69 Page: 69/159 Use domain: professional Risk Management Measures Local exhaust ventilation Effectiveness: 80 % Wear chemically resistant gloves in combination with basic employee Effectiveness: 90 % training. and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC13: Treatment of articles by dipping and pouring. Use domain: professional

70 Page: 70/159 and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) PROC17: Lubrication at high energy conditions and in partly open process. Use domain: professional and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR)

71 Page: 71/159 PROC18: Greasing at high energy conditions. Use domain: professional and reference to its source mg/kg bw/day Risk Characterization Ratio (RCR) mg/m³ Risk Characterization Ratio (RCR) * * * * * * * * * * * * * * * * 8. Short title of exposure scenario End use (industrial, professional) SU2; ERC4; PROC1, PROC2, PROC3, PROC4, PROC5, PROC8a, PROC8b, PROC9, PROC16, PROC17, PROC18 Control of exposure and risk management measures ERC4: Industrial use of processing aids in processes and products, not becoming part of articles Annual amount used in the EU Minimum emission days per year ,000 kg Emission factor air 0 %