Pure-Flo. Bio-Pure.
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1 Pure-Flo Bio-Pure
2 The Bio-Pure is the compact solution for the most demanding Biopharm applications. vailable in fractional sizes and a wide selection of body materials and end connections the Bio-Pure is the ideal choice for sampling and other low flow, high value processes. Bioreactors, chromatography systems, filtration skids are just a small number of applications that will benefit from the compact, reliable performance. Bio-Pure is capable of withstanding typical Steam in Place (SIP) and Clean in Place (CIP) protocols. For demanding Clean out of Place (COP) requirements the manual COP option is the solution for reliable trouble free operation. standard 2 piece PTFE diaphragm prevents separation of the diaphragm, which is common in laminated diaphragm designs. Typical pplications Sampling Bioreactors Chromatography systems Filtration skids Portable vessels Size Range.25,.375,.5 (DN 8, 10, 15) Service Pressure/Temperature 150 psi at 220ºF (10.34 bar at 104ºC) See sizing charts on pg. 6 for exact shutoff pressures Standard Body Materials: STM 182 Grade 316, DIN STM 479 Other materials available upon request vailable End Connections:.5 (DN 15) 16 Gauge.25,.375 (DN 8, 10) 20 Gauge DIN/ISO Tri-Clover Tri-Clamp Corrosion Resistance: Resists alcohol, chloride and most caustic washdowns. 2
3 s vailable Types PTFE Grade TM17 (two piece design) EPDM Grade 17 EPDM Grade E1 Type Size Temperature Compliance Grade Material Inch DN F C FD USP 17, E1 EPDM TM17 PTFE Regulatory Compliance to: FD 21CFR Part 177 US Pharmacopea 31 Class VI Pressure Equipment Directive 97/23/EC EME/4 10/01 - TSE/BSE (Transmitting nimal Spongiform Encephalopathy) 1 For high temperature and/or high cycle applications, contact ITT. 2 Temperature range is as follows: F ( C) for liquid applications F ( C) for continuous steam F ( C) for intermittent steam Interchangeability ll Bio-Pure valves feature a common diaphragm connection. Elastomer and PTFE diaphragms can be interchanged as required on both the manual and actuated bonnets. Installation Bio-Pure diaphragm installation is simplified by utilizing a bayonet diaphragm connection. The diaphragm is inserted into the compressor and turned 90º. The bayonet design provides float to eliminate point loading on PTFE diaphragms. ctuator downward thrust ctuator Stem Compressor Bayonet connection (PTFE, EPDM) Backing Cushion (PTFE diaphragm only) Bayonet diaphragm connection floats along axis 90º General Information Flow Rates Size (in) Size (DN) C v (g/m) K v (m3/h) , , ,36 Note: C v at 1 psi pressure drop, K v at 1 bar pressure drop Weights (Including ctuator and Forged Body) Topworks Lbs Kg Manual 0.6 0,3 ctuated 1.5 0,7 Drain ngle - 30º 3
4 Bio-Pure with Manual Handwheel (BPM) djustable Travel Stop prolongs diaphragm life Robust T-slot compressor/spindle connection Weep hole Visual position indicator Top entry in-line maintenance Standard Features djustable travel stop utoclavable T-Slot compressor Common diaphragm connection (Elastomer, PTFE) Weep hole PTFE and Elastomer diaphragms utilize a common compressor connection Bayonet connection simplifies diaphragm installation and prevents point loading Materials of Construction Bonnet: Stainless steel Spindle: Stainless steel Compressor: Stainless steel Handwheel: PES (polyethersulfone) Dimensions NSI (USOD) Tri-Clamp Buttweld DIN/ISO B Closed B Open In mm 64,3 89,0 89,0 56,6 60,7 31,8 C 4
5 Bio-Pure with Manual COP Handwheel (BPMC) BPM features plus O-Ring seals for clean out of place protocols Standard Features djustable travel stop utoclavable T-Slot compressor Common diaphragm connection (Elastomer, PTFE) O-ring seals Materials of Construction Bonnet: Stainless steel Spindle: Stainless steel Compressor: Stainless steel Handwheel: PES (polyethersulfone) O-ring - FD compliant FKM Dimensions NSI (USOD) Tri-Clamp Buttweld DIN/ISO B Closed B Open In mm 64,3 89,0 89,0 66,4 70,4 31,8 C 5
6 Bio-Pure with dvantage Excel - Series S ctuator Mounting pattern for switches Visual Position Indicator 1/8 NPT air connections positioned in 90º increments for use in tight space applications Stainless steel cylinder and bonnet Maintenance free (welded) construction PTFE and Elastomer diaphragms utilize a common compressor connection Bayonet connection simplifies diaphragm installation and prevents point loading Standard Features Modes of operation Fail close (reverse acting) Fail open (direct acting) Double cting (air to open, air to close) Visual Position indicator Maintenance free design Switch mounting bolt pattern 1/8 NPT air port orientation: In line and perpendicular to flow T-Slot compressor Common diaphragm connection (Elastomer, PTFE) Weep hole Dimensions Materials of Construction Bonnet and housing: Stainless steel Spindle: Stainless steel Compressor: Stainless steel O-rings - FD compliant FKM Fail Close Fail Open Double cting Upper Lower Upper Lower Upper Lower in cm 3 24,47 17,70 26,24 20,86 26,24 24, NSI (USOD) Tri-Clamp Buttweld DIN/ISO B C D Open In mm 64,3 89,0 89,0 90,2 44,5 99,1
7 ctuator Sizing (psi) Fail Close ctuators - ir-to-open, Spring-To-Close (Reverse cting) Maximum Line Pressure ir pressure Spring Package required to open 100% P 0% P for full stroke at 0 psi line pressure Elastomer 60# # PTFE 60# # Fail Open ctuators - ir-to-close, Spring-To-Open (Direct cting) Double cting ctuators - ir-to-close, ir-to-open Line Pressure ir Pressure Required to Close 100% P 0% P 100% P 0% P The exposure of the diaphragm to steam may increase the air requirements to close by as much as 30%. Elastomer PTFE 1 ctuator Sizing (bar) Fail Close ctuators - ir-to-open, Spring-To-Close (Reverse cting) Maximum Line Pressure ir pressure Spring Package required to open 100% P 0% P for full stroke at 0 psi line pressure Elastomer 4 bar 10,34 8,62 4,00 6 bar 10,34 10,34 5,79 PTFE 4 bar bar 10,34 9,65 6,00 Fail Open ctuators - ir-to-close, Spring-To-Open (Direct cting) Double cting ctuators - ir-to-close, ir-to-open Line Pressure ir Pressure Required to Close 100% P 0% P 100% P 0% P 1,38 3,17 2,96 1,45 1,03 2,76 3,38 3,31 1,65 1,38 4,14 3,59 3,59 1,86 1,65 5,52 3,72 3,93 2,00 2,00 6,89 3,93 4,21 2,21 2,28 8,62 4,14 4,62 2,41 2,69 10,34 4,34 4,96 2,62 3,03 1,38 4,96 4,21 3,24 2,48 2,76 5,17 4,55 3,45 2,83 4,14 5,31 4,83 3,59 3,10 5,52 5,45 5,10 3,72 3,38 6,89 5,58 5,38 3,86 3,65 8,62 5,79 5,72 4,07 4,00 10,34 5,93 6,07 4,21 4,34 1 The exposure of the diaphragm to steam may increase the air requirements to close by as much as 30%. Elastomer PTFE 1 7
8 How to Order Body Type Code Description BP Forging Types Code Description 17 EPDM E1 EPDM Pure-Life NGE TM17 PTFE Note: See PFORD brochure for complete figure number definitions. Manual Bonnets Code Description BPM Manual bonnet BPMC Manual bonnet sealed (COP) ctuated Bonnets Code Description XS29 Fail Closed 90# spring package XS26 Fail Closed 60# spring package XS1 Fail Open XS3 Double cting Example.5 Bio-Pure body with Tri-clamp ends 25 μ-in. ID, electropolish ID and OD, modified PTFE diaphragm with EPDM backing cushion. Standard manual bonnet. Figure Number:.5-BP TM17-BPM Main Valve Configuration Example.5 BP TM17 BPM Valve Size.5 Body Type BP Body Ends 419 Mechanical Polish - Interior 6 Mechanical Polish - Exterior 0 Electropolish 3 TM17 Manual Bonnet BPM For more information, please contact: Pure-Flo Headquarters 33 Centerville Road Lancaster, P US Phone +1 (800) Phone +1 (717) Fax +1 (800) Pure-Flo Richards Street Kirkham, Lancashire PR4 2HU, England Phone Fax Website: pureflo.custserv@itt.com 8 BP ITT Corporation Industrial Process
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