MCP Standard. Multi-purpose Saves individual application parameters! Applications. Interfaces. Robust, powerful drive Ideal for dispensing and filling

Size: px

Start display at page:

Download "MCP Standard. Multi-purpose Saves individual application parameters! Applications. Interfaces. Robust, powerful drive Ideal for dispensing and filling"

Liliana O’Connor’
6 years ago
Views:

khz) Start/Stop, Rotation direction, Autostart Pre-programmed tube sizes and pump-heads allow you to work with flow rates Membrane key-pad, LED display 4 program memories for saving individual

1 . 37 Drive for tubing pump-head Multi-purpose Saves individual application parameters! Robust, powerful drive Ideal for dispensing and filling Interfaces PC-controllable: RS3 Speed control ( 5 or V, or 4 ma) Speed output ( V DC or 7. khz) Start/Stop, Rotation direction, Autostart Pre-programmed tube sizes and pump-heads allow you to work with flow rates Membrane key-pad, LED display 4 program memories for saving individual application parameters More than pump-heads available Bayonet coupling system enables a system change without tools Flow rates, channels, rollers and differential pressure depend on the pump-head mounted (see Pages to 5) Dispensing and calibrating function see Page 5 drive (pump-heads on Pages 5) Specifications Motor type DC motor Speed 4 rpm Speed setting rpm, resolution. rpm Flow rate setting µl/min,, l/min Power consumption W Mains connections 3V AC /5Hz,5V AC /Hz adjustable Protection rating IP 3 Depth/Width/Height x 55 x mm (without pump-head) Weight.4 kg (without pump-head) Ordering information The complete pump system consists of: Drive ISM 44 Pump-head Pages to 5 Pages 3 to 39 Accessories Page Foot switch IS 39 Applications With pump-head 3 Filling of pharmaceutical solutions at small production scale (5 to units) in syrup bottles. Controlled via foot switch. With PTFE- pump-head Used as trickle funnel, time-controlled addition of organic solvents during synthesis (small scale pilot plant) US: Germany: /9 3 7

Single-channel pump-heads.45 37 Gentle pumping This pump-head is gentle enough for pumping highly concentrated viable cells Instantly interchangeable pump system IP 5 IP 5 Pro-.

(higher max. flow rate but more pulsation than with 3 rollers) For tubing with mm wall thickness 5 bar differential pressure Pro- 3. 3 ISM 793 Same pump-head as Pro-, but For tubing with.

2 Single-channel pump-heads Gentle pumping This pump-head is gentle enough for pumping highly concentrated viable cells Instantly interchangeable pump system IP 5 IP 5 Pro ISM 75 Coated aluminum pump-head Can be dismantled for cleaning Self-centering tube-track thanks to concave tube-bed and convex rollers, which lengthens the tube-life stainless steel rollers (higher max. flow rate but more pulsation than with 3 rollers) For tubing with mm wall thickness 5 bar differential pressure Pro ISM 793 Same pump-head as Pro-, but For tubing with.4 mm wall thickness.5 bar differential pressure Flow rates/ Model Pro- R-33/R-37 R-33/R-37 MF.49 MF SC MF MF3. SC SC34 37 BVP Standard ISM 444 ISM 44 BVP Process ISM 9 Especially suitable for: Chemical, biotechnological and pharmaceutical applications Food industry Elevated differential pressures (Pro- and Pro-3) Viscous fluids Fluids containing a high content of sensitive solids Applications requiring hygienic conditions, durability and reliability MCP Process ISM 95 Comparisons to gear, piston and centrifugal pumps proved that peristaltic pumps are the only suitable and sterilisable pump system for gently pumping media containing living cells. Pro ISM 79 Same pump-head as Pro-, but 3 stainless steel rollers (less pulsation but lower max. flow rate than with rollers) Pro ISM 797 Same pump-head design as Pro-, but 3 stainless steel rollers (less pulsation but lower max. flow rate than with rollers) For tubing with.4 mm wall thickness.5 bar differential pressure Flow rates/ Model Pro-3 MF.45 MF SC MF3. 5 MF SC SC Flow rates/ R-33/R-37 Model Pro- MF MF33. 5 SC SC Differential pressure depends on tubing material; tubing with small i.d. s enable higher pressures. The flow rates are based on a drive speed of (or.4) to 4 rpm. For the BVP Standard drive the indicated min. flow rates must be multiplied by factor.4. Approx. values: determined with water, at C, no differential pressure, Tygon tubing. Flow rates/ R-33/R-37 Model Pro-3 min max MF MF SC5.. SC US: Germany: /9 3

.45 37 Single-channel pump-heads Application Pumping animal cell cultures A comparison between different peristaltic pump systems was made by Ms Fan Guo and Prof. Dr. U.

Experimental target: Gentle cell delivery Cell viability remains high Cell damage remains low Pump comparison: Cell concentration Test results Pumping application Production monitoring by analyzing

The cells are continuously pumped through an external loop at a constant flow rate ( / reactor volume / hour = 5 ml/h) until a identifiable cell death is observed.

3 Single-channel pump-heads Application Pumping animal cell cultures A comparison between different peristaltic pump systems was made by Ms Fan Guo and Prof. Dr. U. Graf-Hausner of Zurich Technical University Winterthur, and Dr. Joanne Laukart of Ismatec. Experimental target: Gentle cell delivery Cell viability remains high Cell damage remains low Pump comparison: Cell concentration Test results Pumping application Production monitoring by analyzing by-pass cell streams and reactor innoculation. Pump comparison: Viability Method Cultivation of hybridoma cells in spinner bottles. The cells are continuously pumped through an external loop at a constant flow rate ( / reactor volume / hour = 5 ml/h) until a identifiable cell death is observed. Cells ml _ Viability Incubation time (h) With the pump-head Pro- cell death was observed only after 5 hours whilst with the Easy-Load pump-head death occured already after 9 hours. Pumps tested (Colors according to diagram) MCP Process Pro- convex, non-springloaded rollers MCP Process 3AD 3 convex, non-springloaded rollers cell conc. without pump cell conc. with Pro- cell conc. with WM5 cell conc. with 3 AD cell conc. with Easy-Load MCP Process WM5 straight, spring-loaded rollers MCP Process Easy Load 3 straight, nonspring-loaded rollers Comparative parameters Number of pump rollers: or 3. Rollers: spring-loaded vs. non-spring- loaded 3. Tube-bed / roller geometry: convex vs. straight rollers Incubation time (h) Viability without pump Viability with Pro- Viability with WM5 Viability with 3 AD Viability with Easy-Load With the pump-head Pro- a viability of 7% was observed after 5 hours. With the Easy-Load head a viability of only 7% was observed already after 9 hours. The winner: Pro- Thanks to convex rollers and a concave tubebed, the MCP Process Pro- proved to be the gentlest pump system with respect to cell viability and cell concentration. The secret of the Pro- Before the roller totally closes the squeezed tubing, the cells can escape through a gap towards the tubing wall and, hence, are neither «squashed» nor damaged. The pump-head Pro- has convex rollers and the tube-bed is concave. Conclusion The Pro- (mounted either on an MCP or BVP Process drive) is a uniquely designed pump system especially suited for use in biotechnology. It has been tested for use in laboratory scale and small production scale up to 3 liters. US: Germany: /9 3

Single-channel pump-heads.7 3 Multi-purpose single-channel pump-heads For MCP and BVP drives Change the pump-heads within seconds without the use of tools 3.

design thanks to the concave tube-bed and convex rollers (lengthens tube-life) Rotor for tubing i.d. from. to.4 mm with mm wall thickness 3 stainless steel rollers 5 bar differential pressure 3.

4 3 ISM 75 Pressure on tubing adjustable via rollers Rotor accepts tubing with and.4 mm wall thickness and to mm i.d. 3 stainless steel rollers 5 bar differential pressure (with tubing wall thickness mm).

4 Single-channel pump-heads.7 3 Multi-purpose single-channel pump-heads For MCP and BVP drives Change the pump-heads within seconds without the use of tools ISM 79 Easily accessible flip-up tube-bed guarantees easy and rapid tube change-over Transparent protection cover allows monitoring the tube and the revolving rotor Self-centering tube-track design thanks to the concave tube-bed and convex rollers (lengthens tube-life) Rotor for tubing i.d. from. to.4 mm with mm wall thickness 3 stainless steel rollers 5 bar differential pressure 3.44 ISM 7 Same design as pump-head 3, but larger size For tubing i.d. from to 9.5 mm with mm wall thickness 5 bar differential pressure Ideal for sterile media 3AD.4 3 ISM 75 Pressure on tubing adjustable via rollers Rotor accepts tubing with and.4 mm wall thickness and to mm i.d. 3 stainless steel rollers 5 bar differential pressure (with tubing wall thickness mm).5 bar differential pressure (with tubing wall thickness.4 mm) Ideal for media with high viscosity or a certain level of solid content Flow rates / Model 3 R-33/R-37 OEM MF..7 7 MF. MF SC An OEM version of this pump-head is also available. Ask for the detailed data sheet. Flow rates / Model 3 R-33/R-37 MF.44 MF SC MF3. 4 MF3.. SC Differential pressure depends on tubing material; tubing with small i.d. s may enable higher pressures. Flow rates / R-33/R-37 WS iø Model 3AD min. max. MF MF SC MF3. 5 MF SC SC MF MF33. 5 The flow rates are based on a drive speed of (or.4) to 4 rpm. For the BVP Standard drive the indicated min. flow rates must be multiplied by factor.4. Approx. values: determined with water, at C, no differential pressure, and Tygon tubing. US: Germany: /9 3

.7 Single-channel pump-heads The pump-head for PTFE tubing Easy-Load 7 MF 33/ISM73 Easily accessible pump-head Allows rapid tube change-over PSF housing (Polysulfone) Rotor for tubing with mm wall

7 Differential pressure depends on tubing material; tubing with small i.d. s may enable higher pressures.

rollers.7 bar differential pressure Flow rates / R -33/R-37 Model Easy-Load II ml/mi n m in. max. M F. 4 5 M F3.9 S C379 9 4 M F3. 4 73 M F3. 3 pump-heads can be mounted on one drive.

5 .7 Single-channel pump-heads The pump-head for PTFE tubing Easy-Load 7 MF 33/ISM73 Easily accessible pump-head Allows rapid tube change-over PSF housing (Polysulfone) Rotor for tubing with mm wall thickness Rotor with 3 stainless steel rollers.7 bar differential pressure Flow rates / Tygon ST R -33/R-37 Model Easy-Load ml/mi n m in. max. M F.. M F M F3.9 S C M F M F3. 7 Differential pressure depends on tubing material; tubing with small i.d. s may enable higher pressures. Easy-Load II 4 MF 44/ISM73 Same specifications as Easy-Load, but Adjustable pressure setting Improved, automatic tubing retention PPS housing (Polyphenylene sulfide) Rotor with 4 stainless steel rollers.7 bar differential pressure Flow rates / R -33/R-37 Model Easy-Load II ml/mi n m in. max. M F. 4 5 M F3.9 S C M F M F3. 3 pump-heads can be mounted on one drive. (Special mounting sets must be ordered separately). PTFE-Tube.7 45 MF 33/ISM77 Pump-head for PTFE tubing stainless steel rollers Stainless steel rotor Anodized aluminum body Adjustable tube-bed pressure with locking knob Up to.9 bar differential pressure Ideal for dispensing and pumping aggressive chemicals and for the filtration of organic solvents. Flow rates for PTFE- i.d. Flow rates mm.7 to 5 4 mm.9 to 45 See ordering information and tubing below. Ordering information for pump-head PTFE tubing Article Specifications Pack size PTFE pump tubing, 3 cm long mm i.d. / 4 mm o.d., for.7 5 MF 33 pieces PTFE pump tubing, 3 cm long 4 mm i.d. / mm o.d., for.9 45 MF 33 pieces Tube connectors (straight) ( connectors are needed for one tube) for tubing with mm i.d. MF pieces Tube connectors (straight) ( connectors are needed for one tube) for tubing with 4 mm i.d. MF 334 pieces PTFE extension tubing, 3.5 m long for tubing with mm i.d. SC 7BO x 3.5 m PTFE extension tubing, 3.5 m long for tubing with 4 mm i.d. SC BO x 3.5 m grooving tool Important for connections which must withstand (Use only tubing with 4 mm i.d.). bar (4 psi) or greater. MF 337 pieces US: Germany: /9 3 3

3 (with cassettes for 4 channels) (with cassettes for channels) (with cassettes for channels) CA Click n go cassettes (spare cassettes, see Page )

can take different tube sizes -stop tubing,.3 to 3.7 mm i.d. bar differential pressure Ideal pump-head for multi-channel applications at higher flow rates SB3V ISM 734 + ISM Standard tubing.

9 to 53 (depends on tube-bed) Spring-loaded, exchangeable tube-beds Individual and continuously adjustable pressure setting rollers, to 3 channels,

5. SC5.5.34. SC.7.74 SC.3 3 SC4. 4 SC7 5. SC 5.3 SC3.54. 5 SC 3.7.94 3 OEM OEM versions of these pump-heads are also available.

6 Multi-channel pump-heads. Pump-heads up to 4 channels For MCP and BVP drives Change the pump-heads in seconds without tools SBV ISM ISM Standard tubing 3. to. mm i.d. thickness mm CA-4, CA-, CA- ISM 7 CA 4 ISM 73 CA ISM 733 CA. 3 (with cassettes for 4 channels) (with cassettes for channels) (with cassettes for channels) CA Click n go cassettes (spare cassettes, see Page ) Automatic pressure setting Easy and rapid tube change-over; each channel separately, even while pump is running rollers 4 to channels, each channel can take different tube sizes -stop tubing,.3 to 3.7 mm i.d. bar differential pressure Ideal pump-head for multi-channel applications at higher flow rates SB3V ISM ISM Standard tubing. to 4. mm i.d. thickness mm SB V / SB 3V.9 ISM Tube-bed set: -channel, SB V ISM for Standard tubing to 3-channel, SB 3V ISM for Standard tubing.9 to 53 (depends on tube-bed) Spring-loaded, exchangeable tube-beds Individual and continuously adjustable pressure setting rollers, to 3 channels, for Standard tubing Differential pressure 5 bar Ideal for sensitive substances requiring a smooth pressure adjustment Flow rates / R-33/R-37 SC.3..3 SC.5. SC SC.7.74 SC.3 3 SC4. 4 SC7 5. SC 5.3 SC SC OEM OEM versions of these pump-heads are also available. Ask for the detailed data sheet. Flow rates / SBV R-33/R-37 MF3 3. SC MF MF3. 4. R-33/R-37 WT Flow rates / SB3V WT MF..9 MF. 3 MF SC US: Germany: /9 3

. Multi-channel pump-heads IP 5 Instantly interchangeable pump system Choose from 4 drives Memory for up to 4 user-defined programs.

IP 5 for aggressive media, see Page 35. BVP Standard ISM 444 ISM 44 BVP Process ISM 9 MCP Process ISM 95 MS/CA 4-. 57 ISM 735 + max.

rollers for extremely low pulsation 4 channels, extendable up to channels 3 extension blocks with 4 channels each 3-stop tubing,.3 to 3.7 mm i.d. bar differential pressure MS/CA -. ISM 74 + max.

7 . Multi-channel pump-heads IP 5 Instantly interchangeable pump system Choose from 4 drives Memory for up to 4 user-defined programs. Pump-heads and tubing are pre-programmed, which enables you to work with varying flow rates. See Pages 4 to 9. Single-channel pump-heads for MCP and BVP drives: See Pages to 3. IP 5 for aggressive media, see Page 35. BVP Standard ISM 444 ISM 44 BVP Process ISM 9 MCP Process ISM 95 MS/CA ISM max. 3 extension blocks ISM 737 Click n go cassettes (spare cassettes, Page ) Each channel can take different tube sizes. Tube change-over is possible even while pump is running. rollers for extremely low pulsation 4 channels, extendable up to channels 3 extension blocks with 4 channels each 3-stop tubing,.3 to 3.7 mm i.d. bar differential pressure MS/CA -. ISM 74 + max. extension blocks ISM 5 Click n go cassettes (spare cassettes, Page ) Each channel can take different tube sizes. Tube change-over is possible even while pump is running. rollers channels, extendable up to 4 channels extension blocks with channels each 3-stop tubing,.3 to 3.7 mm i.d. bar differential pressure Flow rates / R-33/R-37 SC9.3.. SC SC SC SC SC.75 SC SC SC SC Flow rates / R-33/R-37 SC SC5.5.5 SC SC5.7.4 SC59.73 SC. 4 SC SC 5. 5 SC SC Differential pressure depends on tubing material; tubing with small i.d. s and/or cassettes with the pressure lever (see Page ) may enable higher pressures. The flow rates are based on a drive speed of (or.4) to 4 rpm. For the BVP Standard drive the indicated min. flow rates must be multiplied by factor.4. The indicated flow rates are approx. values: determined with water, at C, no differential pressure, and Tygon tubing. US: Germany: /9 3 5

2009 Catalog. For Dispensing and Filling Applications 0.4 µl/min to 13 liters/min. Featuring Tubing, Gear and Piston Pumps for:

2009 Catalog. For Dispensing and Filling Applications 0.4 µl/min to 13 liters/min. Featuring Tubing, Gear and Piston Pumps for: Ismatec Laboratory Pumps 009 Catalog For Dispensing and Filling Applications 0.4 µl/min to 3 liters/min Featuring Tubing, Gear and Piston Pumps for: Analytics Sampling Biotechnology Process Control ISMATEC,